FABRICATION OF SILK FIBROIN PHOTONIC STRUCTURES BY NANOCONTACT IMPRINTING
    21.
    发明申请
    FABRICATION OF SILK FIBROIN PHOTONIC STRUCTURES BY NANOCONTACT IMPRINTING 有权
    通过纳米压印制造丝光纤光电结构

    公开(公告)号:US20120121820A1

    公开(公告)日:2012-05-17

    申请号:US12741066

    申请日:2008-11-05

    IPC分类号: C08J7/18 B29C59/16

    摘要: A method of manufacturing a nanopatterned biophotonic structure includes forming a customized nanopattern mask on a substrate using E-beam lithography, providing a biopolymer matrix solution, depositing the biopolymer matrix solution on the substrate, and drying the biopolymer matrix solution to form a solidified biopolymer film. A surface of the film is formed with the nanopattern mask, or a nanopattern is machined directly on a surface of the film using E-beam lithograpy such that the biopolymer film exhibits a spectral signature corresponding to the E-beam lithograpy nanopattern. The resulting bio-compatible nanopatterned biophotonic structures may be made from silk, may be biodegradable, and may be bio-sensing devices. The biophotonic structures may employ nanopatterned masks based on non-periodic photonic lattices, and the biophotonic structures may be designed with specific spectral signatures for use in probing biological substances, including displaying optical activity in the form of opalescence.

    摘要翻译: 制造纳米图案生物光子结构的方法包括使用电子束光刻在基底上形成定制的纳米图案掩模,提供生物聚合物基质溶液,将生物聚合物基质溶液沉积在基材上,以及干燥生物聚合物基质溶液以形成固化的生物聚合物膜 。 用纳米图案掩模形成膜的表面,或者使用电子束光刻直接在膜的表面上加工纳米图案,使得生物聚合物膜显示对应于电子束光刻纳米图案的光谱特征。 所得的生物相容纳米图案的生物光子结构可以由丝制成,可以是可生物降解的,并且可以是生物感测装置。 生物光子结构可以使用基于非周期性光子晶格的纳米图案掩模,并且生物光子结构可以被设计成用于探测生物物质的特定光谱特征,包括以乳光的形式显示光学活性。

    AUTHENTICATION SYSTEM, DATA DEVICE, AND METHODS FOR USING THE SAME
    23.
    发明申请
    AUTHENTICATION SYSTEM, DATA DEVICE, AND METHODS FOR USING THE SAME 有权
    认证系统,数据设备及其使用方法

    公开(公告)号:US20050236481A1

    公开(公告)日:2005-10-27

    申请号:US10709208

    申请日:2004-04-21

    摘要: An authentication system may comprise: a first light source, a second light source, and at least three optically filtered light sensing devices for detecting analog emission intensity in a spectral sensitivity range, wherein each light sensing device is in operable communication with the first light source and/or the second light source. The first light source can have a first light source spectral distribution and can be capable of providing sufficient excitation to produce a photoluminescent emission from a medium comprising a luminescent tag and a color. The second light source can have a visible multi-wavelength spectral distribution and can be capable of providing sufficient visible multi-wavelength illumination of the medium to generate a second analog response, wherein the second analog response is different from the photoluminescent emission. Each light sensing device can have a different device spectral sensitivity range which includes at least a portion of the visible multi-wavelength spectral distribution, with the device spectral sensitivity range of at least one of the light sensing devices including at least a portion of a desired photoluminescent emission wavelength range.

    摘要翻译: 认证系统可以包括:第一光源,第二光源和用于检测光谱灵敏度范围中的模拟发射强度的至少三个光学滤波光感测装置,其中每个光感测装置与第一光源可操作地连通 和/或第二光源。 第一光源可以具有第一光源光谱分布,并且能够提供足够的激发以从包含发光标签和颜色的介质产生光致发光发射。 第二光源可以具有可见的多波长光谱分布,并且能够提供媒介的足够的可见多波长照明以产生第二模拟响应,其中第二模拟响应不同于光致发光发射。 每个光感测装置可以具有不同的装置光谱灵敏度范围,该范围包括可见多波长光谱分布的至少一部分,其中至少一个光感测装置的装置光谱灵敏度范围包括至少一部分期望的 光致发光波长范围。

    System for accessing patient information
    24.
    发明申请
    System for accessing patient information 审中-公开
    用于访问患者信息的系统

    公开(公告)号:US20050021376A1

    公开(公告)日:2005-01-27

    申请号:US10785305

    申请日:2004-02-24

    摘要: Certain exemplary embodiments provide a system for accessing patient medical information in a network. The network comprises a plurality of servers. Certain exemplary embodiments of the network further comprise a repository including patient identifiers and associated server identifiers for use in identifying one or more servers that store medical information associated with a particular patient. To respond to a received command or request to display a particular patient's medical information, certain exemplary embodiments of the network comprise a search processor for initiating a search of the repository to locate a particular server identifier associated with an identifier of a particular patient. To respond to a user command, certain exemplary embodiments of the network comprise an interface processor for generating a uniform resource locator (URL) address incorporating a located particular server identifier in a data field and for initiating a request to access stored medical information of a particular patient at a generated URL address hosted by a server.

    摘要翻译: 某些示例性实施例提供用于访问网络中的患者医疗信息的系统。 该网络包括多个服务器。 网络的某些示例性实施例还包括存储库,其包括用于识别存储与特定患者相关联的医疗信息的一个或多个服务器的患者标识符和相关联的服务器标识符。 为了响应所接收的命令或请求来显示特定患者的医疗信息,网络的某些示例性实施例包括搜索处理器,用于发起存储库的搜索以定位与特定患者的标识符相关联的特定服务器标识符。 为了响应用户命令,网络的某些示例性实施例包括接口处理器,用于在数据字段中生成包含定位的特定服务器标识符的统一资源定位符(URL)地址,并且用于发起访问特定服务器的存储医疗信息的请求 在由服务器托管的生成的URL地址的病人。

    Compositions comprising azelastine and methods of use thereof
    27.
    发明申请
    Compositions comprising azelastine and methods of use thereof 审中-公开
    包含氮卓斯汀的组合物及其使用方法

    公开(公告)号:US20070020330A1

    公开(公告)日:2007-01-25

    申请号:US11486454

    申请日:2006-07-14

    摘要: The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comprise one or more pharmaceutically acceptable carriers or excipients that reduce the amount of post-nasal drip, and/or that minimize or mask the unpleasant bitter taste associated with post-nasal drip, of the compositions into the oral cavity, upon intranasal or ocular administration of the compositions. Especially effective excipients used in the compositions of the present invention are hypromellose as a viscosity modifier and sucralose as a taste-masking agent. The invention also provides methods of treating or preventing certain disorders, or symptomatic relief therefrom, by administering the compositions of the invention to a patient, e.g., for the symptomatic relief of allergic rhinitis, non-allergic vasomotor rhinitis, allergic conjunctivitis, as well as other disorders. The compositions and methods of the present invention provide significant value in terms of patient acceptability, convenience, and compliance.

    摘要翻译: 本发明提供包含氮卓斯汀或其药学上可接受的盐或酯的药物组合物,包括盐酸萘曲斯汀和任选的一种或多种另外的活性剂。 优选的这种组合物还包含一种或多种药学上可接受的载体或赋形剂,其减少鼻后滴液的量,和/或将组合物与鼻腔滴注相关的令人不快的苦味最小化或掩盖到口腔中 鼻内或眼部给药组合物。 用于本发明组合物中的特别有效的赋形剂是作为粘度调节剂的羟丙甲纤维素和作为掩味剂的三氯蔗糖。 本发明还提供了通过将本发明的组合物给予患者来治疗或预防某些疾病或症状缓解的方法,例如用于过敏性鼻炎,非过敏性血管舒缩性鼻炎,过敏性结膜炎的症状缓解以及 其他疾病。 本发明的组合物和方法在患者可接受性,方便性和依从性方面提供了显着的价值。

    Wrapping materials for smoking articles
    28.
    发明申请
    Wrapping materials for smoking articles 审中-公开
    用于吸烟物品的包装材料

    公开(公告)号:US20060124146A1

    公开(公告)日:2006-06-15

    申请号:US11351688

    申请日:2006-02-10

    IPC分类号: A24D1/02

    CPC分类号: A24D1/025

    摘要: Smokable rods of cigarettes are manufactured using wrapping materials that incorporate at least one fibrous material (e.g., flax fibers, hardwood pulp fibers and/or softwood pulp fibers) at least one filler material (e.g., calcium carbonate in particulate form). The wrapping materials possess multi-layer coatings. The wrapping materials include coatings in the form of series of spaced apart bands, each band having a series of layers. At least one of the coating layers can have a filler material dispersed or suspended within a film-forming material of that layer. Flavoring agent(s) are included in one or more of the wrapping material itself, a seam adhesive, and/or bands included on the wrapping material.

    摘要翻译: 可吸烟的香烟棒使用包含至少一种纤维材料(例如亚麻纤维,硬木浆纤维和/或软木浆纤维)至少一种填充材料(例如颗粒形式的碳酸钙)的包装材料制造。 包装材料具有多层涂层。 包裹材料包括一系列间隔带形式的涂层,每个带具有一系列层。 涂层中的至少一层可以具有分散或悬浮在该层的成膜材料中的填料。 调味剂包括在包装材料本身,接缝粘合剂和/或包装材料中包含的带中的一种或多种中。

    OPHTHALMIC FORMULATION DERIVED FROM SILK PROTEIN
    30.
    发明申请
    OPHTHALMIC FORMULATION DERIVED FROM SILK PROTEIN 审中-公开
    从丝蛋白衍生的眼科配方

    公开(公告)号:US20140235554A1

    公开(公告)日:2014-08-21

    申请号:US14179034

    申请日:2014-02-12

    摘要: An ophthalmic composition is described for the treatment of dry eye syndrome in a human or mammal. The composition comprises an aqueous solution including an effective amount of silk protein. The aqueous solution comprises from about 0.01% by weight to about 30% by weight of the silk protein. In one embodiment, the silk protein may be fibroin. A method of treating an eye having an ocular surface is also described. The method comprises providing an ophthalmic composition comprising an aqueous solution including an effective amount of silk protein, and administering the ophthalmic composition topically to the ocular surface.

    摘要翻译: 描述了用于治疗人或哺乳动物的干眼综合征的眼用组合物。 组合物包含含有有效量的丝蛋白的水溶液。 该水溶液占丝蛋白质的约0.01重量%至约30重量%。 在一个实施方案中,丝蛋白可以是丝心蛋白。 还描述了一种治疗具有眼表面的眼睛的方法。 该方法包括提供一种眼用组合物,其包含含有有效量的丝蛋白的水溶液,并将眼用组合物局部施用于眼表面。