摘要:
A method of manufacturing a nanopatterned biophotonic structure includes forming a customized nanopattern mask on a substrate using E-beam lithography, providing a biopolymer matrix solution, depositing the biopolymer matrix solution on the substrate, and drying the biopolymer matrix solution to form a solidified biopolymer film. A surface of the film is formed with the nanopattern mask, or a nanopattern is machined directly on a surface of the film using E-beam lithograpy such that the biopolymer film exhibits a spectral signature corresponding to the E-beam lithograpy nanopattern. The resulting bio-compatible nanopatterned biophotonic structures may be made from silk, may be biodegradable, and may be bio-sensing devices. The biophotonic structures may employ nanopatterned masks based on non-periodic photonic lattices, and the biophotonic structures may be designed with specific spectral signatures for use in probing biological substances, including displaying optical activity in the form of opalescence.
摘要:
A lubricant containing a minor amount of a polyalkene-substituted succinimide of Mn 1800 to 2800, as a first base, is circulated through a lubricating system so that the succinimide forms salts with at least a portion of combustion acids therein. The lubricant is then contacted with an immobilised second base, stronger than the first base, that displaces at least a portion of the succinimide from the salts to form retained second base: combustion acid salts and release the succinimide into the lubricant.
摘要:
An authentication system may comprise: a first light source, a second light source, and at least three optically filtered light sensing devices for detecting analog emission intensity in a spectral sensitivity range, wherein each light sensing device is in operable communication with the first light source and/or the second light source. The first light source can have a first light source spectral distribution and can be capable of providing sufficient excitation to produce a photoluminescent emission from a medium comprising a luminescent tag and a color. The second light source can have a visible multi-wavelength spectral distribution and can be capable of providing sufficient visible multi-wavelength illumination of the medium to generate a second analog response, wherein the second analog response is different from the photoluminescent emission. Each light sensing device can have a different device spectral sensitivity range which includes at least a portion of the visible multi-wavelength spectral distribution, with the device spectral sensitivity range of at least one of the light sensing devices including at least a portion of a desired photoluminescent emission wavelength range.
摘要:
Certain exemplary embodiments provide a system for accessing patient medical information in a network. The network comprises a plurality of servers. Certain exemplary embodiments of the network further comprise a repository including patient identifiers and associated server identifiers for use in identifying one or more servers that store medical information associated with a particular patient. To respond to a received command or request to display a particular patient's medical information, certain exemplary embodiments of the network comprise a search processor for initiating a search of the repository to locate a particular server identifier associated with an identifier of a particular patient. To respond to a user command, certain exemplary embodiments of the network comprise an interface processor for generating a uniform resource locator (URL) address incorporating a located particular server identifier in a data field and for initiating a request to access stored medical information of a particular patient at a generated URL address hosted by a server.
摘要:
A method of manufacturing a biopolymer optofluidic device including providing a biopolymer, processing the biopolymer to yield a biopolymer matrix solution, providing a substrate, casting the biopolymer matrix solution on the substrate, embedding a channel mold in the biopolymer matrix solution, drying the biopolymer matrix solution to solidify biopolymer optofluidic device, and extracting the embedded channel mold to provide a fluidic channel in the solidified biopolymer optofluidic device. In accordance with another aspect, an optofluidic device is provided that is made of a biopolymer and that has a channel therein for conveying fluid.
摘要:
A method of manufacturing a microfluidic device having at least one cylindrical microchannel includes providing a substrate, casting an uncured polymer matrix solution onto the substrate, embedding an elongated rod in the uncured polymer matrix solution, curing the polymer matrix solution to form a solidified body, and extracting the elongated rod to form the cylindrical microchannel in the solidified body. In another embodiment, the method includes forming an optical feature on a surface of the microfluidic device. A microfluidic device is also provided, the device including a polymer body, and at least one cylindrical microchannel in the polymer body, the cylindrical microchannel having a diameter between approximately 40 ?m and 250 ?m, inclusive. An additional microfluidic device is provided that functions as an optofluidic spectrometer. The optofluidic spectrometer includes a polymer body, a diffraction grating integrated within the polymer body, and a cylindrical microchannel behind the diffraction grating on the polymer body.
摘要:
The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comprise one or more pharmaceutically acceptable carriers or excipients that reduce the amount of post-nasal drip, and/or that minimize or mask the unpleasant bitter taste associated with post-nasal drip, of the compositions into the oral cavity, upon intranasal or ocular administration of the compositions. Especially effective excipients used in the compositions of the present invention are hypromellose as a viscosity modifier and sucralose as a taste-masking agent. The invention also provides methods of treating or preventing certain disorders, or symptomatic relief therefrom, by administering the compositions of the invention to a patient, e.g., for the symptomatic relief of allergic rhinitis, non-allergic vasomotor rhinitis, allergic conjunctivitis, as well as other disorders. The compositions and methods of the present invention provide significant value in terms of patient acceptability, convenience, and compliance.
摘要:
Smokable rods of cigarettes are manufactured using wrapping materials that incorporate at least one fibrous material (e.g., flax fibers, hardwood pulp fibers and/or softwood pulp fibers) at least one filler material (e.g., calcium carbonate in particulate form). The wrapping materials possess multi-layer coatings. The wrapping materials include coatings in the form of series of spaced apart bands, each band having a series of layers. At least one of the coating layers can have a filler material dispersed or suspended within a film-forming material of that layer. Flavoring agent(s) are included in one or more of the wrapping material itself, a seam adhesive, and/or bands included on the wrapping material.
摘要:
Holographic storage media including a polymeric binder, a photoactive monomer, a photo-initiator, and a stable organic or organometallic dye material are described. The dye may be covalently attached to the polymeric binder, the photoactive monomer, or both. Data may be written into the holographic storage media using light of one wavelength and read using light of a different or the same wavelength.
摘要:
An ophthalmic composition is described for the treatment of dry eye syndrome in a human or mammal. The composition comprises an aqueous solution including an effective amount of silk protein. The aqueous solution comprises from about 0.01% by weight to about 30% by weight of the silk protein. In one embodiment, the silk protein may be fibroin. A method of treating an eye having an ocular surface is also described. The method comprises providing an ophthalmic composition comprising an aqueous solution including an effective amount of silk protein, and administering the ophthalmic composition topically to the ocular surface.