公开(公告)号：US3957874A

公开(公告)日：1976-05-18

申请号：US487236

申请日：1974-07-10

申请人： Toni Dockner ,  Herbert Krug

发明人： Toni Dockner ,  Herbert Krug

IPC分类号： C07B61/00 ,  B01J21/00 ,  C07C67/00 ,  C07C209/00 ,  C07C209/18 ,  C07C211/46 ,  C07C211/48 ,  C07C211/50 ,  C07C87/62 ,  C07C121/50

CPC分类号： C07C209/18

摘要： An improved process for the continuous production of N-alkylarylamines by reaction of arylamines with alkanols and/or dialkyl ethers in the gas phase at a temperature of from 180.degree. to 450.degree.C in the presence of carrier substances which contain an oxyacid of phosphorus. The improvement consists in using silicic acid having an internal surface area of from 50 to 500 square meters per gram and a content of from 0.1 to 20% by weight of phosphoric acid and in the continuous supply of phosphoric acid and/or an alkyl phosphate to the catalyst during the reaction. N-alkylarylamines are starting materials for the production of dyes, pesticides, plant protection agents and growth regulators. They are also suitable as additives to mineral oils or to coating compositions and other polymerized systems.

公开(公告)号：US5900125A

公开(公告)日：1999-05-04

申请号：US119649

申请日：1998-07-21

申请人： Herbert Exner ,  Karl Baur ,  Toni Dockner ,  Christiane Potthoff ,  Albrecht Dams

发明人： Herbert Exner ,  Karl Baur ,  Toni Dockner ,  Christiane Potthoff ,  Albrecht Dams

IPC分类号： C07C67/08 ,  C07C67/54 ,  C07C69/54 ,  B01D3/34 ,  C07C69/52

CPC分类号： C07C67/08

摘要： In a process and an apparatus for the continuous preparation of alkyl esters of (meth)acrylic acid by reacting (meth)acrylic acid and monohydric alkanols of 1 to 8 carbon atoms in the homogeneous, liquid, solvent-free phase at elevated temperatures and in the presence of an acidic esterification catalyst, by feeding the (meth)acrylic acid, the alkanol and the acid catalyst continuously to a reaction zone, the reaction zone consists of a cascade of at least two reaction regions connected in series, and the discharge stream of one reaction region forms a feed stream of a downstream reaction region. The cascade may have from two to four reaction regions is spatially separated from one another.

摘要翻译： 在（甲基）丙烯酸的烷基酯的连续制备方法和装置中，通过使（甲基）丙烯酸和1至8个碳原子的一元链烷醇在均相，液体，无溶剂相中在高温和 酸性酯化催化剂的存在通过将（甲基）丙烯酸，链烷醇和酸催化剂连续进料到反应区，反应区由串联连接的至少两个反应区的级联组成，排出流 的一个反应区域形成下游反应区域的进料流。 级联可能具有两到四个反应区域在空间上彼此分离。

公开(公告)号：US5637760A

公开(公告)日：1997-06-10

申请号：US541414

申请日：1995-10-10

申请人： Toni Dockner ,  Helmut Lermer ,  Klaus Bittins ,  Gerhard Nestler ,  Gundo Brauch

发明人： Toni Dockner ,  Helmut Lermer ,  Klaus Bittins ,  Gerhard Nestler ,  Gundo Brauch

IPC分类号： B01J27/02 ,  C07B61/00 ,  C07C67/08 ,  C07C67/60 ,  C07C69/54 ,  C07C67/48

CPC分类号： C07C67/60

摘要： 1,4-butanediol mono(meth)acrylate is prepared by esterification of (meth)acrylic acid with 1,4-butanediol, by a process in which an aqueous solution of unconverted 1,4-butanediol is obtained, wherein the 1,4-butanediol present in the aqueous solution is converted into readily volatile tetrahydrofuran in the presence of a catalytic amount of a strong acid and the tetrahydrofuran is separated off from the aqueous solution.

摘要翻译： 1,4-丁二醇单（甲基）丙烯酸酯通过（甲基）丙烯酸与1,4-丁二醇的酯化反应来制备，其中获得未转化的1,4-丁二醇的水溶液，其中1,4 丁二醇在催化量的强酸存在下转化为容易挥发的四氢呋喃，四氢呋喃与水溶液分离。

公开(公告)号：US5015785A

公开(公告)日：1991-05-14

申请号：US564323

申请日：1990-08-08

申请人： Werner Steck ,  Helmut Lermer ,  Matthias Schwarzmann ,  Toni Dockner

发明人： Werner Steck ,  Helmut Lermer ,  Matthias Schwarzmann ,  Toni Dockner

IPC分类号： C07C37/00

CPC分类号： C07C37/00 ,  B01J29/40 ,  B01J35/023 ,  B01J37/0009 ,  B01J38/12 ,  B01J2229/42 ,  Y02P20/584

摘要： A process for the preparation of mixtures of isomeric cresols with a molar ratio of para- to meta-cresol of from 0.6:1 to 10:1 by isomerization of cresol mixtures or ortho- and/or metal-cresol on zeolite catalysts of the pentasil type in the gas phase at from 300.degree. to 600.degree. C. under from 0.01 to 50 bar entails the mean particle size of the zeolite catalyst being at leat 3 .mu.m, and the selectivity in the established test for the disproportionation of ethylbenzene to diethylbenzene isomers being at least 60% for para-diethylbenzene.

摘要翻译： 通过将甲酚混合物或邻 - 和/或金属 - 甲酚异构化在戊二烯沸石催化剂上进行异构化，制备异构甲酚与间甲酚摩尔比为0.6:1至10:1的混合物的方法 在300〜600℃的气相中，在0.01〜50巴条件下，沸石催化剂的平均粒径为3微米，乙苯分解成二乙苯时的选择性 对二乙基苯的异构体为至少60％。

公开(公告)号：US4973751A

公开(公告)日：1990-11-27

申请号：US275663

申请日：1988-11-22

申请人： Toni Dockner ,  Eckhard Hickmann ,  Herbert Krug

发明人： Toni Dockner ,  Eckhard Hickmann ,  Herbert Krug

IPC分类号： C07C41/28 ,  C07D307/46

CPC分类号： C07D307/46 ,  C07C41/28

摘要： Compounds of the formula IR.sup.1 --CH.dbd.CH--R.sup.2 Iwhere R.sup.1 is hydrogen or alkyl and R.sup.2 is alkoxy or acylamino, and R.sup.1 and R.sup.2 together may form a heterocyclic ring, are prepared by elimination of the radical R.sup.3 OH from a compound of the formula II ##STR1## where R.sup.1 and R.sup.2 have the above meanings and R.sup.3 is alkyl, by a method in which the elimination is carried out by passing the compound of the formula II in a liquid or gaseous state into a high-boiling mineral oil above the boiling point of compound I being formed, compound I is taken off in gaseous form, and the high-boiling mineral oil enriched with by-products is removed and replaced with fresh mineral oil.

摘要翻译： 式ⅠR1-CH = CH-R2I的化合物，其中R1是氢或烷基，R2是烷氧基或酰基氨基，R1和R2可以一起形成杂环，是通过从 式II其中R1和R2具有上述含义，R3是烷基，其中通过使式II化合物以液态或气态进入高沸点矿物油中进行消除的方法， 在形成化合物I的沸点之上，将化合物I以气态形式除去，并且除去富含副产物的高沸点矿物油并用新的矿物油代替。

公开(公告)号：US4943671A

公开(公告)日：1990-07-24

申请号：US189362

申请日：1988-05-02

申请人： Toni Dockner ,  Manfred Sauerwald ,  Herbert Krug ,  Matthias Irgang

发明人： Toni Dockner ,  Manfred Sauerwald ,  Herbert Krug ,  Matthias Irgang

IPC分类号： C07C1/30 ,  B01J23/745 ,  B01J27/043 ,  C07B61/00 ,  C07C1/00 ,  C07C1/26 ,  C07C11/06 ,  C07C15/04 ,  C07C17/23 ,  C07C17/354 ,  C07C67/00

CPC分类号： C07C1/26 ,  C07C17/23 ,  C07C2523/745 ,  C07C2527/043

摘要： Organic halogen compounds in which one or more halogen atoms are covalently bonded to the carbon are subjected to reductive dehalogenation by reaction with a hydrocarbon in the presence of carbon at elevated temperatures with formation of a hydrogen halide, by a process in which the dehalogenation is carried out in the presence of iron powder or an iron compound as a cocatalyst, at from 100.degree. to 450.degree. C.

摘要翻译： 其中一个或多个卤素原子与碳共价结合的有机卤素化合物通过在碳存在下在碳的存在下在高温下通过卤化氢的形成，通过进行脱卤作用的方法在烃上进行还原脱卤 在铁粉或铁化合物作为助催化剂存在下，在100-450℃下。

公开(公告)号：US4900825A

公开(公告)日：1990-02-13

申请号：US201051

申请日：1988-06-01

申请人： Hermann Koehler ,  Toni Dockner

发明人： Hermann Koehler ,  Toni Dockner

IPC分类号： A61K31/44 ,  A61K31/4427 ,  A61P37/00 ,  C07D233/92 ,  C07D233/94 ,  C07D401/12 ,  C07D473/00 ,  C07D473/38

CPC分类号： C07D233/92 ,  C07D401/12 ,  C07D473/38

摘要： 4-Nitro-5-imidazolyl ethers and thioethers of the formula I ##STR1## where R.sup.1 is alkyl, alkoxyalkyl, cycloalkyl, aryl, aralkyl or alkylaryl, R.sup.2 is hydrogen, alkyl, cycloalkyl, aryl, aralkyl or alkylaryl, R.sup.3 is alkyl, cycloalkyl, aryl, aralkyl, alkylaryl or a heterocyclic or heteroaromatic radical or a counter-ion of the corresponding alcoholate or thiolate or, where X is sulfur, R.sup.3 is hydrogen, and X is oxygen or sulfur, and the stated organic radicals may furthermore carry substituents which are inert under the reaction conditions, are prepared by reacting a dinitroimidazole of the formula II ##STR2## with an alcohol or thiol of the formula IIIR.sup.3 --XH (III)in a solvent or diluent at a pH of the from 4 to 16.

摘要翻译： 4-硝基-5-咪唑基醚和式I的硫醚其中R1是烷基，烷氧基烷基，环烷基，芳基，芳烷基或烷基芳基，R2是氢，烷基，环烷基，芳基，芳烷基或烷基芳基，R3 是烷基，环烷基，芳基，芳烷基，烷基芳基或杂环或杂芳族基团或相应的醇化物或硫醇盐的反离子，或其中X是硫，R 3是氢，X是氧或硫，并且所述有机基团 还可以在反应条件下进行惰性的取代基，其通过使式II（II）的二硝基咪唑与式IIIR 3 -XH（III）的醇或硫醇在溶剂或稀释剂中反应而制备， pH为4至16。

公开(公告)号：US4864030A

公开(公告)日：1989-09-05

申请号：US238121

申请日：1988-08-30

申请人： Hermann Koehler ,  Toni Dockner ,  Helmut Karn

发明人： Hermann Koehler ,  Toni Dockner ,  Helmut Karn

IPC分类号： C07D233/90

CPC分类号： C07D233/90

摘要： Process for the preparation of 1-alkylimidazoles of the general formula (I) ##STR1## where R.sup.1 is alkyl, R.sup.2 and R.sup.3 are hydrogen, alkyl, aryl, arylalkyl, or alkylaryl, R.sup.4 is carboxy, alkoxycarbonyl R.sup.5 OCC--, carbamoyl, or cyano, and R.sup.5 is an alkyl of from 1 to 8 carbon atoms--by the reaction of imidazoles of the general formula (II) ##STR2## with dialkyl sulfates of the general formula (III)(R.sup.1 O).sub.2 SO.sub.2 (III)at elevated temperatures in the presence of a carboxylic acid or anhydride or of both acid and anhydride.

摘要翻译： 制备通式（I）的1-烷基咪唑的方法其中R 1是烷基，R 2和R 3是氢，烷基，芳基，芳基烷基或烷基芳基，R 4是羧基，烷氧基羰基，R 5 OCC - ，氨基甲酰基 ，或氰基，R 5是1至8个碳原子的烷基 - 通式（II）的咪唑与（II）的二烷基硫酸盐（R 1 O）2 SO 2（ III）在羧酸或酸酐或酸和酸酐的存在下在升高的温度下进行。

公开(公告)号：US4845247A

公开(公告)日：1989-07-04

申请号：US76612

申请日：1987-07-23

申请人： Wolfgang Spiegler ,  Norbert Goetz ,  Manfred Sauerwald ,  Toni Dockner ,  Rolf Fischer

发明人： Wolfgang Spiegler ,  Norbert Goetz ,  Manfred Sauerwald ,  Toni Dockner ,  Rolf Fischer

IPC分类号： C07D309/22 ,  C07D309/28 ,  C07D309/32

CPC分类号： C07D309/32 ,  C07D309/22 ,  C07D309/28

摘要： 3,4-dihydro-2H-pyrans I ##STR1## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each H or C.sub.1 -C.sub.6 -alkyl and R.sup.3 is not C.sub.2 -C.sub.4 -alkyl when A is COOR.sup.5 and A is COOR.sup.5, .dbd.CHOR.sup.5, in which R.sup.5 is C.sub.1 -C.sub.4 -alkyl, or CH.sub.2 OR.sup.6, in which R.sup.6 is C.sub.1 -C.sub.4 -alkyl or is benzyl which is unsubstituted or substituted by C.sub.1 -C.sub.4 -alkyl, alkoxy or halogen, or is formyl, C.sub.2 -C.sub.4 -alkylcarbonyl or benzoyl which is unsubstituted or substituted by C.sub.1 -C.sub.4 -alkyl, alkoxy or halogen, are prepared by eliminating an alcohol from a 2-alkoxytetrahydropyran II ##STR2## where R.sup.7 is C.sub.1 -C.sub.18 -alkyl and A' is COOR.sup.5, CH(OR.sup.5).sub.2 or CH.sub.2 OR.sup.6, in which R.sup.5 and R.sup.6 have the meanings stated for I, the elimination being carried out by passing II, in the liquid or gaseous state, into a high boiling mineral oil at above the boiling point of the resulting dihydropyran I, removing I in gaseous form, replenishisng the high boiling mineral oil when it becomes enriched with byproducts, and removing the said mineral oil enriched with byproducts.

摘要翻译： 3,4-二氢-2H-吡喃酮其中R 1，R 2，R 3和R 4各自是H或C 1 -C 6烷基，当A是COOR 5 + L时，R 3不是C 2 -C 4 - 烷基，A是 COOR 5 = CHOR 5，其中R 5是C 1 -C 4 - 烷基或CH 2 OR 6，其中R 6是C 1 -C 4烷基或是未被取代或被C 1 -C 4 - 烷基，烷氧基或卤素取代的苄基，或是甲酰基， 未取代或被C 1 -C 4 - 烷基，烷氧基或卤素取代的C 2 -C 4 - 烷基羰基或苯甲酰基通过从2-烷氧基四氢吡喃II中除去醇来制备，其中R 7是C 1 -C 18烷基和A' 是COOR 5，CH（OR 5）2或CH 2 OR 6，其中R 5和R 6具有I所述的含义，通过使II在液体或气态下进行的消除在高于沸点的高沸点矿物油中进行 的所得二氢吡喃I，除去气体形式的I，当富含副产物时补充高沸点矿物油，并除去富含副产物的所述矿物油。

公开(公告)号：US4803283A

公开(公告)日：1989-02-07

申请号：US126867

申请日：1987-11-30

申请人： Toni Dockner ,  Uwe Kempe ,  Hermann Koehler

发明人： Toni Dockner ,  Uwe Kempe ,  Hermann Koehler

IPC分类号： C07D233/92 ,  C07D233/91

CPC分类号： C07D233/92

摘要： 4(5)-nitroimidazole-5(4)-carboxylic acids are prepared by reacting an imidazole-4(5)-carboxylic acid with a mixture of sulfuric acid and nitric acid at not less than 80.degree. C., the water content of the reaction mixture at the beginning of the reaction being no higher than 5% by weight, based on the reaction mixture.

摘要翻译： 通过使咪唑-4（5） - 羧酸与硫酸和硝酸的混合物在不低于80℃下反应制备4（5） - 硝基咪唑-5（4） - 羧酸， 基于反应混合物，反应开始时的反应混合物不高于5重量％。