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    SURGICAL RETRACTOR TOOL
    23.
    发明申请
    SURGICAL RETRACTOR TOOL 有权

    公开(公告)号：US20210015514A1

    公开(公告)日：2021-01-21

    申请号：US16623027

    申请日：2018-06-08

    Applicant: Norwegian University of Science and Technology

    Inventor： Per Even STORLI ,  Lars Cato REKSTAD ,  Brynjulf YSTGAARD

    IPC: A61B17/29 ,  A61B17/28 ,  A61B17/22

    Abstract: A surgical retractor tool for removing an object from the stomach or from the oesophagus. The tool includes a flexible steerable tube for insertion into the body via the oral cavity and a gripper at the distal end of the tube for gripping an object in the stomach or the oesophagus in order to allow for removal of the object from the stomach or the oesophagus. The gripper includes first and second rotatable gripper surfaces and a clamping mechanism for moving the gripper surfaces to clamp the object. The rotatable gripper surfaces are arranged to rotate relative to the tube in order to allow a longitudinal axis of a gripped object to move into alignment with a longitudinal axis of the tube.

    Surgical stapler, anvil for a surgical stapler, and a method of stapling tissue
    24.
    发明授权
    Surgical stapler, anvil for a surgical stapler, and a method of stapling tissue 有权

    公开(公告)号：US10695067B2

    公开(公告)日：2020-06-30

    申请号：US15551385

    申请日：2017-06-28

    Applicant: Norwegian University of Science and Technology (NTNU)

    Inventor： Lars Cato Rekstad ,  Brynjulf Ystgaard

    IPC: A61B17/115 ,  A61B17/072

    Abstract: A surgical stapler includes a proximal end and a distal end and an anvil at the distal end for providing resistance to staples during the stapling operation of the surgical stapler. The anvil may include a number of segments arranged end-to-end. The anvil is elongated in the collapsed state, the anvil being elongated generally in a first direction D1. The anvil is configured such that the segments rotate about a rotation axis along a perpendicular second direction D2 when the anvil is actuated between the deployed and the collapsed states. The anvil is configured such that adjacent segments pivot relative to each other about a pivot axis along a third direction D3 when the anvil is actuated between the deployed and collapsed states. The stapler also includes an actuator mechanism, wherein the actuator mechanism is configured to be controlled from a location on the surgical stapler towards the proximal end.

    ANTI-BACTERIAL AGENTS AND THEIR USE IN THERAPY
    26.
    发明申请
    ANTI-BACTERIAL AGENTS AND THEIR USE IN THERAPY 审中-公开

    公开(公告)号：US20180141977A1

    公开(公告)日：2018-05-24

    申请号：US15570837

    申请日：2016-05-06

    Applicant: Norwegian University of Science and Technology (NTNU)

    Inventor： Marit OTTERLEI ,  Siri BACHKE

    IPC: C07K14/00 ,  A61K38/17 ,  A61K47/50 ,  C12N5/078 ,  A61L27/22 ,  A61L9/20

    CPC classification number: C07K14/003 ,  A61K38/1709 ,  A61K47/50 ,  A61L9/20 ,  A61L27/227 ,  C07K14/4738 ,  C12N5/0634 ,  Y02A50/402 ,  Y02A50/475 ,  Y02A50/478 ,  Y02A50/479 ,  Y02A50/481

    Abstract: The present invention provides an agent, or a composition containing an agent, for use in treating or preventing a bacterial infection in a subject, wherein said agent comprises: (i) an oligopeptidic compound comprising a PCNA interacting motif and a domain that facilitates the cellular uptake of said compound, wherein the PCNA interacting motif is X1X2X3X4X5X6 (SEQ ID NO: 1) and wherein: X1 is a basic amino acid; X2 is an aromatic amino acid; X3 is an aromatic amino acid or a hydrophobic amino acid that has an R group comprising at least three carbon atoms; X4 is an uncharged amino acid other than an aromatic amino acid, Glycine (G) and Proline (P); X5 is any amino acid other than an acidic amino acid or an aromatic amino acid; and X6 is any amino acid other than an acidic amino acid or an aromatic amino add, preferably a basic amino add or Proline (P), wherein when X3 is not an aromatic amino acid, X5 is not lysine (K) and X6 is a basic amino acid or Proline (P): or (ii) a nucleic acid molecule comprising a sequence encoding the oligopeptidic compound of (i). In certain aspects the agent and composition of the invention may be used as single agents, in other aspects of the invention the agents and composition may be used in conjunction with one or more addition active agents, such as antibiotics, or in combination with UV radiation.

    PROFILING CIRCUITRY
    27.
    发明申请
    PROFILING CIRCUITRY 有权

    公开(公告)号：US20250013471A1

    公开(公告)日：2025-01-09

    申请号：US18694318

    申请日：2022-09-23

    Applicant: Norwegian University of Science and Technology (NTNU) ,  Universiteit Gent

    Inventor： Magnus Jahre ,  Björn Gottschall ,  Lieven Eeckhout

    IPC: G06F9/38 ,  G06F9/30

    Abstract: Profiling circuitry for a processor includes state-determining circuitry that is configured to access information stored by the processor for committing inflight instructions in program order, and to use this information to determine a commit state of the processor. The profiling circuitry also has sampling circuitry which is configured, when the processor is in a first commit state, to output sample data to a sample register or a memory that identifies one or more instructions that are next to be committed by the processor, and, when the processor is in a second commit state, to output sample data to the sample register or memory that identifies an instruction that was last committed by the processor.

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