摘要:
A microarray printing device includes an elongate holder with a plurality of receiving slots and a plurality of printing pins. Each of the printing pins extends through and is linearly movable in a respective one of the slots in the holder, and has head, tip, and shank portions. The shank portion has a surface formed with at least one longitudinal flute extending from the head portion to the tip portion.
摘要:
A pin support assembly includes a pin support frame having a plurality of apertures for supporting an array of pins for dispensing fluids. The pins are supported for longitudinal or nullfloatingnull movement to prevent damage to the pins. An actuation assembly engages an end of each of the pins to ensure that the pins are properly seated in the support frame in a planar fashion. The actuation assembly engages the pins as the pins move relatively toward a head block and disengages the pins as the pins move relatively away from the head block.
摘要:
A holder rack has an array of tubular slots that cooperate with a holder to position an absorbent tip of the holder at a predetermined location. The racks fit over well plates to position each absorbent tip adjacent the bottom of a different well in the well plate to extract dried samples from the absorbent tips. The holders are transported in containers having a frame to receive the holders and a lid to keep them in the container. The absorbent tips can extend through a cap to dry, with the cap connected to the holder to enclose the absorbent tips for transport.
摘要:
A spotter that includes a plurality of spotting heads, each of the plurality of spotting heads having a discharging portion at a tip portion, the plurality of spotting heads form an m×n array (m, n>1) with m spotting heads arranged lengthwise and n spotting heads arranged crosswise; and a pitch varying mechanism configured to vary an array pitch of the plurality of spotting heads arrayed in a lengthwise direction and an array pitch of the plurality of spotting heads arrayed in a crosswise direction.
摘要:
An apparatus and method for transferring plurality of samples from one sample container to another one is disclosed wherein each sample is randomly accessible and can be “cherry picked”. The disclosed method of actuation allows for using a smaller number of actuators than the number of sample transferring channels or pins and thereby simplifies the design and control of the sample transferring apparatus.
摘要:
An apparatus and method for transferring plurality of samples from one sample container to another one is disclosed wherein each sample is randomly accessible and can be “cherry picked”. The disclosed method of actuation allows for using a smaller number of actuators than the number of sample transferring channels or pins and thereby simplifies the design and control of the sample transferring apparatus.
摘要:
The present invention relates to a samples delivering device, a method of manufacturing a samples applicator, a method of delivering samples, and a base activation device which can handle a plurality of various samples, efficiently and promptly. The invention is constructed so as to have: one or more sets of vessels capable of accommodating fluids containing predetermined samples to be delivered to a base or one or more sets of vessels, a samples supply section having a samples applicator, wherein two or more retention tips capable of retaining a small quantity of fluids by being dipped in each of the fluids accommodated in the vessels are arranged according to the vessels, and a transfer means for relatively moving between the base and the one or more sets of vessels, and the applicator.
摘要:
A device for support and protection of a tubular element having a single-piece construction, an open configuration and a closed configuration, comprising: a base portion, a side-portion and at least one living hinge interconnecting the side-portion to the base portion. The base portion comprises a plurality of recesses on a surface, each recess being delimited by a plurality of pins, each pin having an indentation. The plurality of indentations form a pocket by which the tubular element is held. The at least one living hinge opens such that the side-portion is substantially parallel to the base portion in the open configuration and the at least one living hinge closes such that the side-portion forms a protective shell about the base portion in the closed configuration.
摘要:
The invention is based on the realization that feedback control for the vertical drive of a pin head becomes unnecessary if one instead prealigns the relative heights of the spotting surface and the well plates such that the pins in the pin head are lowered to the same absolute height both for picking up liquid from the well plates and depositing it onto the spotting surface. By aligning the heights of the well plates and spotting surfaces, the vertical drive of the pin head needs only to be able to reproducibly and accurately arrive at a single lowered position. A pin head can provide this functionality by having a mechanically defined bottom point, obviating the need for a complex and costly feedback control system for height determination of the pins. A simple, low-cost micro-arrayer can thus be provided.