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21.
公开(公告)号:US20230392185A1
公开(公告)日:2023-12-07
申请号:US18451748
申请日:2023-08-17
Applicant: CAP DIAGNOSTICS, LLC, DBA PATHNOSTICS
Inventor: David A. Baunoch , Miguel F.R. Penaranda , Michael L. Opel , Maher Badir , Natalie Luke
CPC classification number: C12Q1/08 , G01N21/59 , G01N2021/593 , G01N21/5907
Abstract: Methods for identifying and providing information about inhibiting growth of polymicrobial infections, including but not limited to providing statistics or information about the likelihood of success in inhibiting growth of a polymicrobial infection with particular compositions or therapeutic solutions. The methods herein feature detection and identification of organisms of the polymicrobial sample (e.g., polymicrobial infection), phenotypic pooled sensitivity tests for determining the susceptibility or resistance of the polymicrobial sample (e.g., polymicrobial infection) in the sample to an antibiotic or other therapeutic agent, and identification of resistance genes, e.g., genetic markers that may indicate resistance to a particular treatment. Together, the data can be applied against databases of antibiotic/therapeutic susceptibility or resistance for particular known polymicrobial samples (e.g., polymicrobial infections) in order to provide information related to the likelihood of success of one or more therapeutic solutions for the polymicrobial sample (e.g., polymicrobial infection).
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公开(公告)号:US20150291994A1
公开(公告)日:2015-10-15
申请号:US14684049
申请日:2015-04-10
Applicant: MAK Wood, Inc.
Inventor: Mark A. Brudnak , Eric J. Baer
IPC: C12Q1/06
Abstract: This disclosure provides methods for enumeration of microorganisms within a freeze-dried powder suspected of containing Lactobacilli or Bifidobacteria.
Abstract translation: 本公开提供了在怀疑含有乳杆菌或双歧杆菌的冷冻干燥粉末中计数微生物的方法。
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公开(公告)号:US08247219B2
公开(公告)日:2012-08-21
申请号:US11811504
申请日:2007-06-11
Applicant: Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor: Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
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公开(公告)号:US08119423B2
公开(公告)日:2012-02-21
申请号:US11400610
申请日:2006-04-07
Applicant: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: G01N33/53
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品中多种所选分析物中一种或多种的存在,不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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公开(公告)号:US08067226B2
公开(公告)日:2011-11-29
申请号:US11431363
申请日:2006-05-10
Applicant: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: G01N33/553
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品中多种所选分析物中一种或多种的存在,不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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公开(公告)号:US08062883B2
公开(公告)日:2011-11-22
申请号:US11651317
申请日:2007-01-09
Applicant: Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor: Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: C12M1/34
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. The device includes a substrate which defines a sample-distribution network having (i) a sample inlet, (ii) one or more detection chambers, and (iii) channel means providing a dead-end fluid connection between each of the chambers and the inlet Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品的一种或多种选择的分析物的存在,不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 该装置包括限定样品分配网络的基板,其具有(i)样品入口,(ii)一个或多个检测室,以及(iii)通道装置,其在每个室之间提供死端流体连接,并且入口 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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公开(公告)号:US07687280B2
公开(公告)日:2010-03-30
申请号:US11807536
申请日:2007-05-29
Applicant: Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor: Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: G01N33/543 , G01N15/06 , G01N33/53 , G01N33/566 , G01N21/00 , C12Q1/68 , B32B5/02 , B32B27/12 , B01L3/00 , C12M1/34
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品中多种所选分析物中一种或多种的存在,不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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公开(公告)号:US07381571B2
公开(公告)日:2008-06-03
申请号:US11362475
申请日:2006-02-24
Applicant: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: G01N33/543 , G01N15/06 , G01N33/53 , G01N33/566 , G01N21/00 , C12Q1/68 , B32B5/02 , B32B27/12 , B01L3/00 , C12M1/34
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品中多种所选分析物中一种或多种的存在,不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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公开(公告)号:US07381570B2
公开(公告)日:2008-06-03
申请号:US11350320
申请日:2006-02-08
Applicant: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: G01N33/543 , G01N15/06 , G01N33/53 , G01N33/566 , G01N21/00 , C12M1/34 , C12Q1/68 , B32B5/02 , B32B27/12 , B01L3/00
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
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公开(公告)号:US20060281066A1
公开(公告)日:2006-12-14
申请号:US11150322
申请日:2005-06-13
Applicant: Samuel Martin
Inventor: Samuel Martin
IPC: A01N1/02
CPC classification number: G01N33/56905 , A01N1/02 , A01N1/0221 , C12Q1/08 , Y02A50/55
Abstract: Methods for the diagnosis of visceral, cutaneous and canine leishmaniasis in a subject suspected of being infected with the parasitic protozoa Leishmania is disclosed. Disclosed are antibody-capture enzyme-linked immunosorbent assays (ELISAs) for the detection of antibodies to Leishmania parasite soluble antigens and antigen-capture ELISAs for the detection of Leishmania parasite soluble antigens in host samples. Also disclosed are immunodiagnostic kits for the detection of Leishmania parasite circulating antigens or IgM and IgG antibodies in a sample from subject having visceral, cutaneous or canine leishmaniasis. In these methods and kits, detection may be done photometrically or visually. The methods and kits also allow the visualization of Leishmania amastigotes or promastigotes in a sample.
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