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公开(公告)号：US08247219B2
公开(公告)日：2012-08-21
申请号：US11811504
申请日：2007-06-11
Applicant: Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
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公开(公告)号：US08119423B2
公开(公告)日：2012-02-21
申请号：US11400610
申请日：2006-04-07
Applicant: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: G01N33/53
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品中多种所选分析物中一种或多种的存在，不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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公开(公告)号：US08067226B2
公开(公告)日：2011-11-29
申请号：US11431363
申请日：2006-05-10
Applicant: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: G01N33/553
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品中多种所选分析物中一种或多种的存在，不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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公开(公告)号：US08062883B2
公开(公告)日：2011-11-22
申请号：US11651317
申请日：2007-01-09
Applicant: Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: C12M1/34
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. The device includes a substrate which defines a sample-distribution network having (i) a sample inlet, (ii) one or more detection chambers, and (iii) channel means providing a dead-end fluid connection between each of the chambers and the inlet Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品的一种或多种选择的分析物的存在，不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 该装置包括限定样品分配网络的基板，其具有（i）样品入口，（ii）一个或多个检测室，以及（iii）通道装置，其在每个室之间提供死端流体连接，并且入口 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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公开(公告)号：US07687280B2
公开(公告)日：2010-03-30
申请号：US11807536
申请日：2007-05-29
Applicant: Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: G01N33/543 , G01N15/06 , G01N33/53 , G01N33/566 , G01N21/00 , C12Q1/68 , B32B5/02 , B32B27/12 , B01L3/00 , C12M1/34
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品中多种所选分析物中一种或多种的存在，不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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Patent Agency Ranking
公开(公告)号：US07381571B2
公开(公告)日：2008-06-03
申请号：US11362475
申请日：2006-02-24
Applicant: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: G01N33/543 , G01N15/06 , G01N33/53 , G01N33/566 , G01N21/00 , C12Q1/68 , B32B5/02 , B32B27/12 , B01L3/00 , C12M1/34
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及一种用于同时测试样品中多种所选分析物中一种或多种的存在，不存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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公开(公告)号：US07381570B2
公开(公告)日：2008-06-03
申请号：US11350320
申请日：2006-02-08
Applicant: Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy M. Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
IPC: G01N33/543 , G01N15/06 , G01N33/53 , G01N33/566 , G01N21/00 , C12M1/34 , C12Q1/68 , B32B5/02 , B32B27/12 , B01L3/00
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
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公开(公告)号：US20060188917A1
公开(公告)日：2006-08-24
申请号：US11400610
申请日：2006-04-07
Applicant: Timothy Woudenberg , Michael Albin , Reid Kowallis , Yefim Raysberg , Robert Ragusa , Emily Winn-Deen
Inventor： Timothy Woudenberg , Michael Albin , Reid Kowallis , Yefim Raysberg , Robert Ragusa , Emily Winn-Deen
IPC: C12Q1/68
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include an analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
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公开(公告)号：US20050186684A1
公开(公告)日：2005-08-25
申请号：US11104156
申请日：2005-04-12
Applicant: Timothy Woudenberg , Michael Albin , Reid Kowallis , Yefim Raysberg , Robert Ragusa , Emily Winn-Deen
Inventor： Timothy Woudenberg , Michael Albin , Reid Kowallis , Yefim Raysberg , Robert Ragusa , Emily Winn-Deen
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: A method for making a test device is provided. The method can comprise providing (a) a substrate comprising a plurality of wells, wherein each well comprises at least one dimension no greater than 1 mm; (ii) a robotic dispensing system comprising at least one piezoelectric dispenser; and (iii) a liquid solution comprising at least one analyte-specific reagent. The method further comprises delivering a volume of the liquid solution into at least some of the wells using the at least one piezoelectric dispenser. The volume can be no greater than about 1 microliter. The method can further comprise placing a cover over the wells.
Abstract translation: 提供了一种制造测试装置的方法。 该方法可以包括提供（a）包含多个孔的基底，其中每个孔包括至少一个不大于1mm的尺寸; （ii）包括至少一个压电分配器的机器人分配系统; 和（iii）包含至少一种分析物特异性试剂的液体溶液。 该方法还包括使用至少一个压电分配器将一定体积的液体溶液输送到至少一些孔中。 体积可以不大于约1微升。 所述方法还可以包括在所述孔上放置盖。
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公开(公告)号：US07888108B2
公开(公告)日：2011-02-15
申请号：US11811501
申请日：2007-06-11
Applicant: Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
Inventor： Timothy Woudenberg , Michael Albin , Reid B. Kowallis , Yefim Raysberg , Robert P. Ragusa , Emily S. Winn-Deen
CPC classification number: C12Q1/6816 , B01J2219/00317 , B01J2219/00599 , B01J2219/00722 , B01L3/5027 , B01L3/502715 , B01L3/50851 , B01L7/52 , B01L2200/027 , B01L2200/0642 , B01L2300/0816 , B01L2300/0864 , B01L2300/1827 , B01L2400/049 , C12Q1/08 , C40B40/06 , C40B50/08 , C40B60/14 , G01N21/6452 , G01N2035/00148 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/809 , Y10T436/143333 , Y10T436/25 , C12Q2565/631
Abstract: The invention is directed to a method and device for simultaneously testing a sample for the presence, presence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, device for detecting or quantitating a plurality of different analytes in a liquid sample. Each chamber may include analyte-specific reagent effective to react with a selected analyte that may be present in the sample, and detection means for detecting the signal. Also disclosed are methods utilizing the device.
Abstract translation: 本发明涉及用于同时测试样品中多种所选分析物中一种或多种的存在，存在和/或量的方法和装置。 本发明在一个方面包括用于检测或定量液体样品中的多种不同分析物的装置。 每个室可以包括有效地与可能存在于样品中的选定分析物反应的分析物特异性试剂和用于检测信号的检测装置。 还公开了利用该装置的方法。
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