Abstract:
The present invention relates to a method for the diagnosis and prognosis of cancers using an epigenetic marker consisting of a specific single CpG site in TTP (Tristetraprolin) promoter and treatment of cancers by regulating its epigenetic status. Particularly, the present invention relates to a method for the diagnosis and prognosis of liver cancer by measuring specific methylation of C, the 32nd residue of the nucleic acid sequence represented by SEQ. ID. NO. 41, and a method for treatment of cancer by regulating the same. The present invention can be effectively used for the diagnosis and/or treatment of liver cancer characterized by TTP down-regulation and methylation of C, the 32nd residue of the nucleic acid sequence represented by SEQ. ID. NO. 41. The present invention can be further applied for the diagnosis and treatment of other cancers or inflammatory diseases that are characterized by TTP down-regulation and methylation of C, the 32nd residue of the nucleic acid sequence represented by SEQ. ID. NO. 41.
Abstract translation:本发明涉及使用由TTP(Tristetraprolin)启动子中的特定单个CpG位点组成的表观遗传标记和通过调节其表观遗传学状态来治疗癌症来诊断和预后的方法。 特别地,本发明涉及通过测定由SEQ ID NO:1表示的核酸序列的第32个残基的C的特异性甲基化来诊断和预测肝癌的方法。 ID。 没有。 41,以及通过调节癌症治疗癌症的方法。 本发明可有效地用于诊断和/或治疗特征为TTP下调和甲基化的肝癌,即SEQ SEQ ID NO:1所示的核酸序列的第32个残基。 ID。 没有。 41.本发明可以进一步应用于以TTP下调和甲基化为特征的其他癌症或炎性疾病的诊断和治疗,C是SEQ ID NO:1所示的核酸序列的第32个残基。 ID。 没有。 41。
Abstract:
A process for preparing a solid electrolytic capacitor comprising application of coverage enhancing catalyst followed by application of a conducting polymer layer. Coverage enhancing catalyst is removed after coating and curing.
Abstract:
A frequency tunable filter comprises a housing having a plurality of walls therein defining a plurality of cavities; a cover mounted on the housing; a plurality of resonators contained in the cavities; at least one sliding member located between the cover and the resonators; and a plurality of metal tuning elements attached to a lower part of the sliding member, wherein frequency tuning is performed by sliding of the sliding member.
Abstract:
A method of programming a nonvolatile memory device comprises applying positive pulses and negative pulses simultaneously to a memory cell array to program at least one memory cell included in the memory cell array.
Abstract:
A plasma reactor has high durability with performance to generate stable and uniform plasma. The reactor has a variety of advantages such as increasing the range of commercial applications since the reactor has a structure that allows simple and efficient installation and operation in a system at a position required by the system. The reactor includes a stack constructed by sequentially stacking plus and minus electrodes and spacers and a reactor body provided at one side of the stack to hold the stack. The plus and minus electrodes are arranged alternately with spacers to define passages through which gas is allowed to pass. Each of the plus and minus electrodes has deformation preventing means to disperse stress of the electrodes and to prevent a local thermal stress caused by thermal expansion and contraction, thereby increasing thermal shock-resistant performance. External terminals for connection to the plus and minus electrodes are provided on the reactor body. A projection is formed on a surface of the reactor body in a direction perpendicular to a stack direction of the stack to allow the reactor to be easily fixed to a case.
Abstract:
A method performed by a wireless node includes receiving policies for data offloading; identifying a user associated with a data flow to which a user device is attached; determining whether data offloading is permitted for the user based on the policies; and performing data offloading when it is determined that data offloading is permitted for the user, wherein data offloading includes routing the data flow away from at least one of a higher layer traffic aggregation device relative to the wireless node or a higher hierarchical controlling device relative to the wireless node.
Abstract:
A method, system, apparatus, article of manufacture, and computer readable storage medium provide the ability to reconstruct a pipe from point cloud data. Point cloud data is obtained. Primitive geometric shapes are detected in the point cloud data. A pipeline is determined by determining predecessor and successor primitive geometric shapes for each of the shapes. Diameters, coplanarity, and angles between the shapes are corrected. The shapes are connected and output.
Abstract:
An optical recording medium is provided, the optical recording medium including a plurality of zones configured to store data corresponding to an adaptive write pulse, the adaptive write pulse including a first pulse, a last pulse, and a multi-pulse train, the adaptive write pulse being different for each of the plurality of zones, the plurality of zones being reflected by a grouping table, the grouping table being configured to generate an adaptive write pulse waveform by varying a position of a rising edge of a first pulse of a mark to be written according to a length of the mark to be written and a leading space, the adaptive write pulse waveform being generated without regard for a trailing space of a present mark being written using the adaptive write pulse waveform, the adaptive write pulse being configured to correspond to the adaptive write pulse waveform, and store rising edge data of the first pulse of the adaptive write pulse waveform varying according to corresponding stored values of lengths of marks to be written. A width of the first pulse is varied by varying the position of the rising edge.
Abstract:
Disclosed is an electronic control brake system capable of ensuing pedal force upon regenerative braking or brake-by-wire control. The electronic control brake system having a simulation function includes a master cylinder for forming oil pressure corresponding to displacement of a brake pedal, an oil tank for providing oil to the master cylinder, a cut-off valve installed on a hydraulic supply pipe that connects an inlet of the master cylinder with an inlet valve of a hydraulic brake, an oil return pipe for connecting an outlet valve of the hydraulic brake with an inlet of the oil tank, and a simulation valve installed on a differential adjusting pipe, which connects the hydraulic supply pipe with the oil return pipe, to generate pedal force.
Abstract:
The present invention relates to novel fluorinated dyes or colorants having high solubility and low viscosity in halogenated, especially fluorinated, solvents. The dyes or colorants of the present invention have shown to improve the performance of electrophoretic displays. The invention is particularly directed to a fluorinated porphyrin dye or colorant expressed by Formula (VII).