公开(公告)号：US20110105446A1

公开(公告)日：2011-05-05

申请号：US12763030

申请日：2010-04-19

Applicant: John Daniel Dobak

Inventor： John Daniel Dobak

IPC: A61K31/137 ,  A61K31/167 ,  A61K31/56 ,  A61K31/573 ,  A61K31/58 ,  A61K31/4535 ,  A61P43/00

CPC classification number: A61K31/138 ,  A61K9/0014 ,  A61K9/0019 ,  A61K9/0021 ,  A61K9/5031 ,  A61K31/167 ,  A61K31/195 ,  A61K31/4535 ,  A61K31/567 ,  A61K31/573 ,  A61K31/58 ,  A61K47/10 ,  A61K47/14 ,  A61K47/34 ,  A61K47/36

Abstract: Compositions, formulations, methods, and systems for treating regional fat deposits comprise contacting a targeted fat deposit with a composition comprising long acting beta-2 adrenergic receptor agonist and a compound that reduces desensitization of the target tissue to the long acting beta-2 adrenergic receptor agonist, for example, glucocorticosteroids and/or ketotifen. Embodiments of the composition are administered, for example, by injection, and/or transdermally.

Abstract translation: 用于治疗局部脂肪沉积物的组合物，制剂，方法和系统包括使目标脂肪沉积物与包含长效β-2肾上腺素能受体激动剂和减少靶组织对长效β-2肾上腺素能受体脱敏的化合物接触 激动剂，例如糖皮质激素和/或酮替芬。 组合物的实施方案例如通过注射和/或经皮施用。

公开(公告)号：US07937144B2

公开(公告)日：2011-05-03

申请号：US11804498

申请日：2007-05-17

Applicant: John Daniel Dobak

Inventor： John Daniel Dobak

IPC: A61N1/32

CPC classification number: A61N1/36085 ,  A61N1/36007 ,  A61N1/36017 ,  A61N1/36071

Abstract: A method is described for the treatment of obesity or other disorders, by electrical activation or inhibition of the sympathetic nervous system. This activation or inhibition can be accomplished by electrically stimulating the greater splanchnic nerve or other portion of the sympathetic nervous system using an implantable pulse generator. This nerve activation can result in reduced food intake and increased energy expenditure. Reduced food intake may occur through a variety of mechanisms that reduce appetite and cause satiety. Increased adrenal gland hormone levels will result in increased energy expenditure. Fat and carbohydrate metabolism, which are also increased by sympathetic nerve activation, will accompany the increased energy expenditure.

公开(公告)号：US20110046421A1

公开(公告)日：2011-02-24

申请号：US12734610

申请日：2008-11-07

Applicant: Berian John Daniel ,  Benjamin Patrick Gracey

Inventor： Berian John Daniel ,  Benjamin Patrick Gracey

IPC: C07C29/149

CPC classification number: C07C29/149 ,  C07C51/12 ,  C07C67/00 ,  Y02E50/32 ,  Y02P20/582 ,  C07C31/08 ,  C07C53/08 ,  C07C69/14

Abstract: The present invention relates to a process for the production of ethanol from a carbonaceous feedstock, wherein the carbonaceous feedstock is first converted to synthesis gas which is then converted to ethanoic acid, which is then subject to a two stage hydrogenation process by which at least a part of the ethanoic acid is converted by a primary hydrogenation process to ethyl ethanoate, which ethyl ethanoate is converted by a secondary hydrogenation process to produce ethanol.

Abstract translation: 本发明涉及从含碳原料生产乙醇的方法，其中碳质原料首先转化为合成气，然后将其转化成乙酸，然后将其转化为两阶段氢化方法，通过该方法将至少一种 乙酸的一部分通过初级氢化方法转化成乙酸乙酯，乙酸乙酯通过二级氢化方法转化成乙醇。

公开(公告)号：US07874448B1

公开(公告)日：2011-01-25

申请号：US12247173

申请日：2008-10-07

Applicant: John Daniel Doherty ,  Claudio Marino

Inventor： John Daniel Doherty ,  Claudio Marino

IPC: B65D25/14 ,  B05C21/00

CPC classification number: B44D3/126

Abstract: The paint tray liner apparatus provides removable fit to an existing paint tray, thereby providing a disposable liner. Flexible sides are collapsible and the liner bottom relatively rigid. The collapsible sides provide for reduced space storage of the apparatus, whether prior to use or after when discarded. The collapsible sides each has an inner panel spaced apart from an outer panel. Each inner and outer panel is connected by the continuous shelf. The side panels thereby fit the sides of a paint tray, with the apparatus tray bottom against a paint tray bottom.

Abstract translation: 油漆盘衬垫装置提供可拆卸的装配到现有的油漆盘，从而提供一次性衬垫。 柔性侧面是可折叠的，并且衬垫底部相对刚性。 可折叠的侧面提供装置的减少的空间存储，无论是在使用之前还是在丢弃之后。 可折叠的侧面各自具有与外板间隔开的内板。 每个内外板通过连续架连接。 侧板由此装配在油漆盘的侧面，装置托盘底部抵靠油漆盘底部。

公开(公告)号：US20110004034A1

公开(公告)日：2011-01-06

申请号：US12734629

申请日：2008-11-07

Applicant: Berian John Daniel ,  Jon Michael Stewart Deeley ,  Benjamin Patrick Gracey ,  Cong Rong Li

Inventor： Berian John Daniel ,  Jon Michael Stewart Deeley ,  Benjamin Patrick Gracey ,  Cong Rong Li

IPC: C07C31/08

CPC classification number: C07C29/159 ,  C07C29/149 ,  C07C29/1518 ,  C07C51/12 ,  C07C67/08 ,  C23F14/02 ,  Y02P20/582 ,  C07C31/08 ,  C07C31/04 ,  C07C53/08 ,  C07C69/14

Abstract: The present invention relates to an improved process for the production of ethanol from a carbonaceous feedstock; wherein the carbonaceous feedstock is first converted to synthesis gas which is then converted to ethanoic acid, which is then esterified and which is then hydrogenated to produce ethanol.

Abstract translation: 本发明涉及一种用于从碳质原料生产乙醇的改进方法; 其中碳质原料首先转化为合成气，然后将其转化为乙酸，然后将其酯化，然后将其氢化生成乙醇。

公开(公告)号：US20100317948A1

公开(公告)日：2010-12-16

申请号：US12817585

申请日：2010-06-17

Applicant: Thomas M. DiMauro ,  Jeffrey K. Sutton ,  Mohamed Attawia ,  Hassan Serhan ,  John Daniel Malone ,  Timothy Beardsley

Inventor： Thomas M. DiMauro ,  Jeffrey K. Sutton ,  Mohamed Attawia ,  Hassan Serhan ,  John Daniel Malone ,  Timothy Beardsley

IPC: A61B5/1459

CPC classification number: A61L31/146 ,  A61B17/866 ,  A61F2/30767 ,  A61F2/34 ,  A61F2/36 ,  A61F2/3662 ,  A61F2/38 ,  A61F2/4455 ,  A61F2002/30663 ,  A61F2002/30929 ,  A61F2002/30981 ,  A61F2002/3611 ,  A61F2002/3625 ,  A61F2002/443 ,  A61F2310/00023 ,  A61F2310/00604 ,  A61F2310/0061 ,  A61F2310/00616 ,  A61L27/06 ,  A61L27/427 ,  A61L27/56 ,  A61L31/022 ,  A61L31/124 ,  A61M5/158 ,  A61N5/0601 ,  A61N5/0624 ,  A61N2005/0651 ,  A61N2005/0661 ,  B01J35/004

Abstract: An implant comprises a photocatalytic layer on at least one surface and is adapted to act as a sensor. In some embodiments, the photocatalytic layer is a semiconductor oxide that is doped. According to some embodiments, the implant comprises a wave guide. According to some embodiments the implant comprises a light port. According to some embodiments, the implant comprises a reflective material on a surface of the waveguide. According to some embodiments the implant comprises a composite material comprising a first material that has a transmissivity when exposed to a predetermined wavelength of light and a second material that has photocatalytic activity when exposed to the predetermined wavelength of light. According to some embodiments the implant comprises a light source adapted to irradiate the photocatalytic surface.

Abstract translation: 植入物包括在至少一个表面上的光催化层，并且适于作为传感器。 在一些实施方案中，光催化层是掺杂的半导体氧化物。 根据一些实施例，植入物包括波导。 根据一些实施例，植入物包括光端口。 根据一些实施例，植入物在波导的表面上包括反射材料。 根据一些实施例，植入物包括复合材料，其包括当暴露于预定波长的光时具有透射率的第一材料和当暴露于预定波长的光时具有光催化活性的第二材料。 根据一些实施例，植入物包括适于照射光催化表面的光源。

公开(公告)号：US07757791B2

公开(公告)日：2010-07-20

申请号：US12059940

申请日：2008-03-31

Applicant: John Daniel Belnap ,  Stewart N. Middlemiss

Inventor： John Daniel Belnap ,  Stewart N. Middlemiss

IPC: E21B10/46

CPC classification number: E21B10/567 ,  B22F7/06 ,  B22F2005/001 ,  B22F2998/00 ,  Y10T428/30 ,  B22F2207/03

Abstract: Cutting elements of this invention include an ultra hard body joined with a metallic substrate. The body includes an uppermost layer comprising a plurality of bonded ultra hard crystals and interstitial regions, and that form a body working surface. The uppermost layer includes a thermally stable outer region that is substantially free of a catalyst material. The body includes an intermediate layer joined to the uppermost layer, comprising a plurality of bonded ultra hard crystals, and having a wear resistance less than that of the uppermost layer remaining region. The intermediate material can include a catalyst and other materials. The ultra hard crystals can be diamond, and the volume fraction of crystals in the uppermost layer can be greater than that in the intermediate layer. The body may additionally include a lowermost PCD layer interposed between and attached to the intermediate layer and the substrate.

Abstract translation: 本发明的切割元件包括与金属基底连接的超硬体。 主体包括包含多个粘结的超硬晶体和间隙区域的最上层，并且形成身体工作表面。 最上层包括基本上不含催化剂材料的热稳定的外部区域。 主体包括连接到最上层的中间层，包括多个结合的超硬晶体，并且具有比最上层剩余区域的耐磨性更低的耐磨性。 中间材料可以包括催化剂和其它材料。 超硬晶体可以是金刚石，并且最上层中的晶体的体积分数可以大于中间层中的晶体的体积分数。 主体可以另外包括介于中间层和衬底之间并附着于中间层和衬底的最下面的PCD层。

公开(公告)号：US20100137267A1

公开(公告)日：2010-06-03

申请号：US12445571

申请日：2007-10-16

Applicant: John Daniel Dobak

Inventor： John Daniel Dobak

IPC: A61K31/567 ,  A61P3/04

CPC classification number: A61K31/58 ,  A61K9/0014 ,  A61K9/0019 ,  A61K9/0048 ,  A61K9/0053 ,  A61K9/06 ,  A61K9/08 ,  A61K9/16 ,  A61K31/135 ,  A61K31/137 ,  A61K31/167 ,  A61K31/569 ,  A61K31/575 ,  A61K45/06 ,  A61K2300/00

Abstract: Compositions, formulations, methods, and systems for treating regional fat deposits and fat-related conditions, dermal conditions, and muscular conditions. Methods comprise administering a composition comprising at least one compound that reduces desensitization of beta adrenergic receptors, for example a glucocorticosteroid, and/or at least one long-acting beta-2 adrenergic receptor agonist, for example, formoterol. Compositions to be administered include sustained release formulations comprising at least one long-acting beta-2 adrenergic receptor agonist, at least one compound that reduces desensitization of beta adrenergic receptors, or both in a sustained crystalline microparticle form.

Abstract translation: 用于治疗局部脂肪沉积物和脂肪相关病症，皮肤状况和肌肉状况的组合物，制剂，方法和系统。 方法包括施用包含至少一种减少β-肾上腺素能受体脱敏的化合物的组合物，例如糖皮质激素和/或至少一种长效β-2肾上腺素能受体激动剂，例如福莫特罗。 待施用的组合物包括包含至少一种长效β-2肾上腺素能受体激动剂的至少一种缓释制剂，至少一种减少β-肾上腺素能受体脱敏的化合物或两者以持续的结晶微粒形式。

公开(公告)号：US20100023049A1

公开(公告)日：2010-01-28

申请号：US12572769

申请日：2009-10-02

Applicant: John Daniel ,  Brian J. Lowe ,  Robert Cassell ,  Bradley F. Slaker ,  John E. Arnold, JR. ,  Thomas E. Broome

Inventor： John Daniel ,  Brian J. Lowe ,  Robert Cassell ,  Bradley F. Slaker ,  John E. Arnold, JR. ,  Thomas E. Broome

IPC: A61F2/01

CPC classification number: A61F2/013 ,  A61F2/01 ,  A61F2002/011 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61F2250/0023 ,  A61F2250/0098

Abstract: A filter disposed at the distal end of an elongate guidewire. Catheters are provided for delivering the filter to, and retrieving the filter from, a treatment site. The catheters can be over-the-wire or single operator exchange. The catheters include a housing for receiving the filter therein. The housing has an atraumatic distal end.

Abstract translation: 设置在细长导丝的远端的过滤器。 提供导管用于将过滤器输送到治疗部位并从治疗部位检索过滤器。 导管可以是线上或单个操作者交换。 导管包括用于在其中接收过滤器的壳体。 房屋有一个无创的远端。

公开(公告)号：US20100016947A1

公开(公告)日：2010-01-21

申请号：US12566622

申请日：2009-09-24

Applicant: John Daniel Dobak, III

Inventor： John Daniel Dobak, III

IPC: A61F2/06 ,  B21F1/00

CPC classification number: A61F2/82 ,  A61F2/07 ,  A61F2/89 ,  A61F2002/075 ,  A61F2002/30199 ,  A61F2230/0063 ,  A61F2240/004

Abstract: A system and method are provided for making a customized stent or stent graft, including the steps of obtaining a digital image of the endoluminal shape of an artery or the blood flow channel of an aneurysm, processing the obtained image to create a three dimensional model of the shape or channel, and fabricating a scaffold around the model such that the scaffold substantially conforms to the model.

Abstract translation: 提供一种用于制造定制的支架或支架移植物的系统和方法，包括以下步骤：获得动脉瘤的腔内形状或动脉瘤的血流通道的数字图像，处理所获得的图像以产生三维模型 形状或通道，以及围绕模型制造支架，使得支架基本上符合模型。