公开(公告)号：US08598314B2

公开(公告)日：2013-12-03

申请号：US12680539

申请日：2008-09-26

Applicant: Soumitra S. Ghosh ,  Josue Alfaro-Lopez ,  Lawrence J. D'Souza ,  Odile Esther Levy ,  Qing Lin ,  Christopher J. Soares

Inventor： Soumitra S. Ghosh ,  Josue Alfaro-Lopez ,  Lawrence J. D'Souza ,  Odile Esther Levy ,  Qing Lin ,  Christopher J. Soares

IPC: A61K38/00 ,  C07K5/00 ,  C07K7/00 ,  C07K16/00 ,  C07K17/00

CPC classification number: A61K47/64 ,  A61K47/545 ,  A61K47/55

Abstract: Peptide-peptidase inhibitor conjugate molecules and methods of manufacture thereof are disclosed. These conjugate molecules are useful as agents for the treatment and prevention of metabolic and cardiovascular diseases, disorders, and conditions. Such diseases, conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, insulin-resistance, obesity, and diabetes mellitus of any kind, and other diabetes-related disorders.

Abstract translation: 公开了肽肽酶抑制剂缀合物分子及其制备方法。 这些缀合物分子可用作治疗和预防代谢和心血管疾病，病症和病症的药剂。 这些疾病，病症和障碍包括但不限于高血压，血脂异常，心血管疾病，进食障碍，胰岛素抵抗，肥胖症和任何类型的糖尿病以及其它与糖尿病有关的疾病。

公开(公告)号：US08586707B2

公开(公告)日：2013-11-19

申请号：US12561107

申请日：2009-09-16

Applicant: Qing Lin ,  Mike Madden

Inventor： Qing Lin ,  Mike Madden

IPC: A61K38/00 ,  A61K38/04 ,  C07K5/00 ,  C07K7/00 ,  C07K16/00 ,  C07K17/00

CPC classification number: C07K1/045 ,  C07K1/107 ,  C07K1/1136

Abstract: A method for preparing stapled peptides. The stapled peptides, including helical stapled peptides, are prepared according to a photochemically-based method, a [3+2] cycloaddition reaction. The helical stapled peptides exhibit increased helicity, thermal stability and cell permeability.

Abstract translation: 一种制备缝合肽的方法。 根据光化学方法[3 + 2]环加成反应制备包装螺旋缝合肽的缝合肽。 螺旋缝合肽表现出增加的螺旋度，热稳定性和细胞渗透性。

公开(公告)号：US20130014289A1

公开(公告)日：2013-01-10

申请号：US13580935

申请日：2010-02-24

Applicant: Jinsong Zhang ,  Shouyi Chen ,  Canfang Niu ,  Biao Ma ,  Wanke Zhang ,  Qing Lin ,  Sijie He

Inventor： Jinsong Zhang ,  Shouyi Chen ,  Canfang Niu ,  Biao Ma ,  Wanke Zhang ,  Qing Lin ,  Sijie He

IPC: A01H5/00 ,  A01H1/02 ,  A01H5/10 ,  C12N15/82

CPC classification number: C07K14/415 ,  C12N15/8271

Abstract: Compositions and methods for imparting stress tolerance to plants using WRKY nucleic acid and polypeptides.

Abstract translation: 使用WRKY核酸和多肽赋予植物胁迫耐受性的组合物和方法。

公开(公告)号：US08076590B2

公开(公告)日：2011-12-13

申请号：US12198343

申请日：2008-08-26

Applicant: Hui-Chen Zhao ,  Qing-Lin Zhou

Inventor： Hui-Chen Zhao ,  Qing-Lin Zhou

IPC: H05K1/11 ,  H05K1/03

CPC classification number: H05K1/0245 ,  H05K1/0219 ,  H05K1/0222 ,  H05K1/115 ,  H05K2201/09227 ,  H05K2201/09236 ,  H05K2201/09636

Abstract: A printed circuit board includes a first signal via, a second signal via, and a first ground via. A distance between the first ground via and the first signal via is substantially equal to a distance between the first ground via and the second signal via.

Abstract translation: 印刷电路板包括第一信号通孔，第二信号通孔和第一接地通孔。 第一接地通孔和第一信号通孔之间的距离基本上等于第一接地通孔和第二信号通孔之间的距离。

公开(公告)号：US20110095731A1

公开(公告)日：2011-04-28

申请号：US12730155

申请日：2010-03-23

Applicant: Qing-Lin Zhao ,  Ming-Zhu Li ,  Zhi-Hong Ye ,  Xue-Feng Tang ,  Xin Guo ,  Yu-Li Feng

Inventor： Qing-Lin Zhao ,  Ming-Zhu Li ,  Zhi-Hong Ye ,  Xue-Feng Tang ,  Xin Guo ,  Yu-Li Feng

IPC: G05F1/70

CPC classification number: H02M1/4225 ,  Y02B70/126 ,  Y02P80/112

Abstract: A power factor correction controller is utilized for a power factor correction circuit in a critical conduction mode of an electric power converter. The power factor correction controller generates a control voltage according to an output voltage outputted from the electric power converter, and utilizes a first threshold value to detect the control voltage. The power factor correction controller can control the power factor correction circuit to operate in different modes according to various levels of a load. Therefore, an objective according to the present invention for reducing electric power consumption of the electric power converter in a light load or a no-load mode and improving energy transmission efficiency can be attained.

Abstract translation: 功率因数校正控制器用于电力转换器的临界导通模式中的功率因数校正电路。 功率因数校正控制器根据从电力转换器输出的输出电压产生控制电压，利用第一阈值检测控制电压。 功率因数校正控制器可以根据负载的各种级别控制功率因数校正电路在不同模式下工作。 因此，可以实现根据本发明的用于在轻负载或空载模式中降低功率转换器的功率消耗并提高能量传输效率的目的。

公开(公告)号：US20090041458A1

公开(公告)日：2009-02-12

申请号：US11934003

申请日：2007-11-01

Applicant: QING LIN

Inventor： QING LIN

IPC: H04J14/00

CPC classification number: H04Q11/0067 ,  H04L12/2861 ,  H04L12/2874 ,  H04L12/2885 ,  H04L45/62 ,  H04L67/00 ,  H04L69/22 ,  H04Q2011/0079

Abstract: A passive optical network (PON) system utilizing a data link layer protocol for communication is disclosed. The PON system may include an optical network unit (ONU). The PON system may also include an optical line terminal (OLT) configured to communicate with the ONU utilizing an Ethernet frame. The Ethernet frame may include at least a source application identifier and a destination application identifier. The source application identifier may represent a source application residing in at least one of the OLT and the ONU. The destination application identifier may represent one or more destination applications configured to receive data from the source application.

Abstract translation: 公开了一种利用数据链路层协议进行通信的无源光网络（PON）系统。 PON系统可以包括光网络单元（ONU）。 PON系统还可以包括被配置为使用以太网帧与ONU进行通信的光线路终端（OLT）。 以太网帧可以至少包括源应用标识符和目的应用标识符。 源应用标识符可以表示驻留在OLT和ONU中的至少一个中的源应用。 目的地应用标识符可以表示被配置为从源应用接收数据的一个或多个目的地应用。

公开(公告)号：US20080138339A1

公开(公告)日：2008-06-12

申请号：US11895207

申请日：2007-08-22

Applicant: Hualiang Huang ,  Xin Jiang ,  Min Fang ,  Jie Feng ,  Ping Zhou ,  Xiaocong Yu ,  Qing Lin

Inventor： Hualiang Huang ,  Xin Jiang ,  Min Fang ,  Jie Feng ,  Ping Zhou ,  Xiaocong Yu ,  Qing Lin

IPC: A61K39/395 ,  C12N15/11 ,  C07K16/18 ,  A61P43/00 ,  C12N15/00 ,  C12N1/20

CPC classification number: C07K16/2809 ,  C07K16/3069 ,  C07K2317/31 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/622

Abstract: The present invention provides an anti-ovarian cancer bispecific antibody. Said antibody includes two polypeptide domains connected by a polypeptide linker, one is anti-ovarian cancer antibody, or its Fab fragment, single complementarity determining region (CDR) antibody or single chain Fv (scFv) and the other is anti-CD3 antibody, or its Fab fragment, single CDR antibody or scFv. The present invention also provides DNA sequences encoding said antibody, an expression vector containing said DNA sequence, and a host cell containing said expression vector.

Abstract translation: 本发明提供了抗卵巢癌双特异性抗体。 所述抗体包括通过多肽接头连接的两个多肽结构域，一个是抗卵巢癌抗体或其Fab片段，单互补决定区（CDR）抗体或单链Fv（scFv），另一个是抗CD3抗体，或 其Fab片段，单CDR抗体或scFv。 本发明还提供编码所述抗体的DNA序列，含有所述DNA序列的表达载体和含有所述表达载体的宿主细胞。

公开(公告)号：US20190085591A1

公开(公告)日：2019-03-21

申请号：US16137487

申请日：2018-09-20

Applicant: Alan Qing-Lin ZHU

Inventor： Alan Qing-Lin ZHU

IPC: E04H17/20

Abstract: An elbow for fence post includes an elbow body and a connector. The elbow body and the fence post are connected through the connector. An insertion hole is opened in the middle of the connector, and the lower end of the elbow body is configured to be inserted into the insertion hole under an interference fit. The outer ring of the connector has an annular groove which is configured to be embeds into the upper end of the post and connects with the external diameter under an interference fit.

公开(公告)号：US20190085588A1

公开(公告)日：2019-03-21

申请号：US16137488

申请日：2018-09-20

Applicant: Alan Qing-Lin ZHU

Inventor： Alan Qing-Lin ZHU

IPC: E04H17/14 ,  E04H17/16

Abstract: A fence accessory includes at least two ornament bodies, each of the at least two ornament bodies including a first connecting part and a second connecting part at two opposing ends thereof. The first connecting part of one of the at least two ornament bodies and the second connecting part of an other one of the at least two ornament bodies are configured to be connected to a fence bar and clamped together as one unit. Moreover, each of the first connecting part and the second connecting part includes a hook and a slot at two opposing sides of the first connecting part and the second connecting part. The hook of the first connecting part of one ornament body is configured to connect to the slot of the second connecting part of an adjacent accessory body.

公开(公告)号：US08759295B2

公开(公告)日：2014-06-24

申请号：US12785396

申请日：2010-05-21

Applicant: Soumitra S. Ghosh ,  Josue Alfaro-Lopez ,  Lawrence J. D'Souza ,  Odile Esther Levy ,  Qing Lin ,  Christopher J. Soares

Inventor： Soumitra S. Ghosh ,  Josue Alfaro-Lopez ,  Lawrence J. D'Souza ,  Odile Esther Levy ,  Qing Lin ,  Christopher J. Soares

IPC: A61K38/26 ,  C07K14/605 ,  C07K19/00 ,  A61P3/10 ,  A61P9/00 ,  A61P9/04 ,  A61P9/08 ,  A61P9/10 ,  A61P9/12

CPC classification number: A61K47/48246 ,  A61K47/545 ,  A61K47/55 ,  A61K47/64

Abstract: Peptide-peptidase inhibitor conjugate molecules are disclosed. These conjugate molecules are useful as agents for the treatment and prevention of metabolic and cardiovascular diseases, disorders, and conditions. Such diseases, conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, insulin-resistance, obesity, and diabetes mellitus of any kind, and other diabetes-related disorders.

Abstract translation: 公开了肽 - 肽酶抑制剂缀合物分子。 这些缀合物分子可用作治疗和预防代谢和心血管疾病，病症和病症的药剂。 这些疾病，病症和障碍包括但不限于高血压，血脂异常，心血管疾病，进食障碍，胰岛素抵抗，肥胖症和任何类型的糖尿病以及其它与糖尿病有关的疾病。