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公开(公告)号:US20190264278A9
公开(公告)日:2019-08-29
申请号:US16212441
申请日:2018-12-06
Applicant: 10X GENOMICS, INC.
Inventor: Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Serge Saxonov , Paul Hardenbol , Rajiv Bharadwaj , Xinying Zheng , Phillip Belgrader
IPC: C12Q1/6874 , C12Q1/6869 , C12Q1/6806 , C12Q1/6855
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号:US10253364B2
公开(公告)日:2019-04-09
申请号:US15980473
申请日:2018-05-15
Applicant: 10X GENOMICS, INC.
Inventor: Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mima Jarosz , Serge Saxonov , Paul Hardenbol , Rajiv Bharadwaj , Xinying Zheng , Phillip Belgrader
IPC: C12Q1/68 , C12Q1/6874 , C12Q1/6806 , C12Q1/683 , C12Q1/6804
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号:US20190032129A1
公开(公告)日:2019-01-31
申请号:US16144832
申请日:2018-09-27
Applicant: 10X GENOMICS, INC.
Inventor: Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Serge Saxonov , Rajiv Bharadwaj
IPC: C12Q1/6874 , C12Q1/683 , C12Q1/6804 , C12Q1/6806
CPC classification number: C12Q1/6874 , C12Q1/6804 , C12Q1/6806 , C12Q1/683 , C12Q2525/191 , C12Q2535/122 , C12Q2537/143 , C12Q2537/149 , C12Q2563/149 , C12Q2563/159 , C12Q2563/179 , C12Q2565/629
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号:US20190024166A1
公开(公告)日:2019-01-24
申请号:US16138448
申请日:2018-09-21
Applicant: 10X GENOMICS, INC.
Inventor: Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Serge Saxonov , Paul Hardenbol , Rajiv Bharadwaj , Xinying Zheng , Phillip Belgrader
IPC: C12Q1/6874 , C12Q1/683 , C12Q1/6804 , C12Q1/6806
CPC classification number: C12Q1/6874 , C12Q1/6804 , C12Q1/6806 , C12Q1/683 , C12Q2525/191 , C12Q2535/122 , C12Q2537/143 , C12Q2563/149 , C12Q2563/159 , C12Q2563/179 , C12Q2565/629
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号:US20190017115A9
公开(公告)日:2019-01-17
申请号:US15980473
申请日:2018-05-15
Applicant: 10X GENOMICS, INC.
Inventor: Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mima Jarosz , Serge Saxonov , Paul Hardenbol , Rajiv Bharadwaj , Xinying Zheng , Phillip Belgrader
IPC: C12Q1/6874 , C12Q1/683 , C12Q1/6804 , C12Q1/6806
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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36.
公开(公告)号:US10150117B2
公开(公告)日:2018-12-11
申请号:US15717847
申请日:2017-09-27
Applicant: 10X Genomics, Inc.
Inventor: Rajiv Bharadwaj , Kevin Ness , Debkishore Mitra , Donald Masquelier , Anthony Makarewicz , Christopher Hindson , Benjamin Hindson , Serge Saxonov
Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.
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公开(公告)号:US09975122B2
公开(公告)日:2018-05-22
申请号:US14934044
申请日:2015-11-05
Applicant: 10X Genomics, Inc.
Inventor: Donald A. Masquelier , Benjamin Hindson , Kevin Ness , Rajiv Bharadwaj
CPC classification number: B01L3/50273 , B01L9/527 , B01L2200/027 , B01L2200/0673 , B01L2200/10 , B01L2300/043 , B01L2300/0609 , B01L2300/0636 , B01L2300/0864 , B01L2300/10 , B01L2300/14 , B01L2300/18 , B01L2400/0487 , B01L2400/0605 , C12Q1/6874 , F16K99/0057 , F16K2099/0084
Abstract: An integrated system for processing and preparing samples for analysis may include a microfluidic device including a plurality of parallel channel networks for partitioning the samples including various fluids, and connected to a plurality of inlet and outlet reservoirs, at least a portion of the fluids comprising reagents, a holder including a closeable lid hingedly coupled thereto, in which in a closed configuration, the lid secures the microfluidic device in the holder, and in an open configuration, the lid is a stand orienting the microfluidic device at a desired angle to facilitate recovery of partitions or droplets from the partitioned samples generated within the microfluidic device, and an instrument configured to receive the holder and apply a pressure differential between the plurality of inlet and outlet reservoirs to drive fluid movement within the channel networks.
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38.
公开(公告)号:US20180015473A1
公开(公告)日:2018-01-18
申请号:US15717847
申请日:2017-09-27
Applicant: 10X Genomics, Inc.
Inventor: Rajiv Bharadwaj , Kevin Ness , Debkishore Mitra , Donald Masquelier , Anthony Makarewicz , Christopher Hindson , Benjamin Hindson , Serge Saxonov
CPC classification number: B01L3/502761 , B01L3/0241 , B01L3/502784 , B01L2200/0673 , B01L2300/0816 , B01L2400/049 , B01L2400/086 , G01N35/085 , G01N2035/00237 , G01N2035/1034
Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.
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公开(公告)号:US20170114390A1
公开(公告)日:2017-04-27
申请号:US15376582
申请日:2016-12-12
Applicant: 10X Genomics, Inc.
Inventor: Benjamin Hindson , Serge Saxonov , Kevin Ness , Paul Hardenbol , Michael Schnall-Levin , Mirna Jarosz
IPC: C12Q1/68
CPC classification number: C12Q1/6874 , C12Q1/6806 , C12Q1/6855 , C12Q1/6869 , C12Q2525/161 , C12Q2535/122 , C12Q2563/159 , C12Q2563/179 , C12Q2565/514
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号:US20150376700A1
公开(公告)日:2015-12-31
申请号:US14752589
申请日:2015-06-26
Applicant: 10X Genomics, Inc.
Inventor: Michael Schnall-Levin , Mirna Jarosz , Christopher Hindson , Kevin Ness , Serge Saxonov , Benjamin Hindson , Grace X. Y. Zheng , Patrick Marks , John Stuelpnagel
CPC classification number: C12Q1/6883 , C12Q1/6827 , C12Q2600/156 , G16B30/00 , C12Q2535/122 , C12Q2537/16 , C12Q2563/159 , C12Q2565/629
Abstract: The present disclosure relates to methods, compositions and systems for haplotype phasing and copy number variation assays. Included within this disclosure are methods and systems for combining the barcode comprising beads with samples in multiple separate partitions, as well as methods of processing, sequencing and analyzing barcoded samples.
Abstract translation: 本公开涉及用于单倍型定相和拷贝数变异测定的方法,组合物和系统。 本公开内容包括用于将包含珠粒的条形码与多个单独分区中的样本组合的方法和系统,以及处理,排序和分析条形码样本的方法。
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