公开(公告)号：US20060167058A1

公开(公告)日：2006-07-27

申请号：US11335669

申请日：2006-01-20

申请人： Yukiyoshi Yamazaki ,  Tsutomu Toma ,  Masahiro Nishikawa ,  Hajime Yamada ,  Hidefumi Ozawa ,  Ayumu Okuda ,  Kazutoyo Abe

发明人： Yukiyoshi Yamazaki ,  Tsutomu Toma ,  Masahiro Nishikawa ,  Hajime Yamada ,  Hidefumi Ozawa ,  Ayumu Okuda ,  Kazutoyo Abe

IPC分类号： A61K31/4439 ,  A61K31/428 ,  A61K31/423 ,  A61K31/4184

CPC分类号： C07D263/58

摘要： The present invention provides a compound selectively activating PPARα, which is useful as a medicament. The present invention is specifically directed to a benzoic acid derivative represented by the following general formula (1): wherein A represents an oxygen atom, a nitrogen atom, or a sulfur atom; R represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group, a cycloalkyl group, a cycloalkyl-alkyl group, an aryl group, an aryl-alkyl group an aryl-oxy-alkyl group, a pyridyl-alkyl group, an alkoxycarbonyl-alkyl group, or a carboxy-alkyl group; X represents an oxygen atom, an NH group, or an S(O)n group (wherein n represents an integer of 0, 1, or 2); and m represents an integer from 2 to 8; or a salt thereof. The present invention also provides a medicament comprising the benzoic acid derivative or the salt thereof as an active ingredient.

摘要翻译： 本发明提供选择性活化PPARα的化合物，其可用作药物。 本发明具体涉及由以下通式（1）表示的苯甲酸衍生物：其中A表示氧原子，氮原子或硫原子; R表示氢原子，烷基，烯基，炔基，环烷基，环烷基 - 烷基，芳基，芳基 - 烷基，芳氧基 - 烷基，吡啶基 - 烷基 ，烷氧基羰基 - 烷基或羧基 - 烷基; X表示氧原子，NH基或S（O）n N（其中n表示0,1或2的整数）; m表示2〜8的整数， 或其盐。 本发明还提供了包含苯甲酸衍生物或其盐作为活性成分的药物。

公开(公告)号：US07002437B2

公开(公告)日：2006-02-21

申请号：US10456173

申请日：2003-06-06

申请人： Masaki Takeuchi ,  Hajime Yamada ,  Hideki Kawamura ,  Daisuke Nakamura ,  Yukio Yoshino

发明人： Masaki Takeuchi ,  Hajime Yamada ,  Hideki Kawamura ,  Daisuke Nakamura ,  Yukio Yoshino

IPC分类号： H03H9/15 ,  H03H9/54

CPC分类号： H03H9/02133 ,  H03H9/0095 ,  H03H9/02102 ,  H03H9/02149 ,  H03H9/174

摘要： A piezoelectric thin-film resonator includes a supporting substrate. A piezoelectric thin-film is formed on the supporting substrate. A lower electrode and an upper electrode are formed with the piezoelectric thin-film therebetween. The stiffness of at least one of the lower and upper electrodes is higher than that of the piezoelectric thin-film.

摘要翻译： 压电薄膜谐振器包括支撑衬底。 在支撑基板上形成压电薄膜。 下电极和上电极之间形成有压电薄膜。 下电极和上电极中的至少一个的刚度高于压电薄膜的刚度。

公开(公告)号：US06609367B2

公开(公告)日：2003-08-26

申请号：US09820683

申请日：2001-03-30

申请人： Tetsuya Nakayasu ,  Mikio Sagara ,  Kyo Takahashi ,  Noritoshi Iwase ,  Hajime Yamada ,  Atsushi Murakami

发明人： Tetsuya Nakayasu ,  Mikio Sagara ,  Kyo Takahashi ,  Noritoshi Iwase ,  Hajime Yamada ,  Atsushi Murakami

IPC分类号： F01N700

CPC分类号： F01N13/14 ,  F01N3/28 ,  F01N3/2853 ,  F01N2240/36 ,  F01N2410/10 ,  F01N2590/04 ,  F02B61/02 ,  F02B2075/1816 ,  F02D9/04 ,  F02M35/10013 ,  F02M35/10039 ,  F02M35/10065 ,  F02M35/10216 ,  F02M35/10255 ,  F02M35/112 ,  F02M35/162 ,  F16K5/0647 ,  F16K31/465 ,  Y10T137/86566

摘要： In an exhaust control valve having a valve housing and a valve body rotatably contained in the valve housing, a transmission member is fitted to an outer end of the valve shaft and protrudes from the outside of the valve housing. A bearing bushing for rotatably bearing an external circumferential surface of the valve shaft by its internal circumferential surface and rotatably bearing an end face of the valve body by its end face is mounted in the valve housing. The valve body is urged by load from a thrust spring for achieving a pressure contact seal condition between the opposed end faces of the bearing bush and the valve body.

摘要翻译： 在具有阀壳体和可旋转地容纳在阀壳体中的阀体的排气控制阀中，传动构件装配到阀轴的外端并从阀壳体的外部突出。 用于通过其内周表面可旋转地支承阀轴的外周表面并通过其端面可旋转地支承阀体的端面的轴承衬套安装在阀壳体中。 阀体由推力弹簧的负载推动，以实现轴承衬套的相对端面与阀体之间的压力接触密封状态。

公开(公告)号：US5885978A

公开(公告)日：1999-03-23

申请号：US626963

申请日：1996-04-03

申请人： Hajime Yamada ,  Akira Yamada

发明人： Hajime Yamada ,  Akira Yamada

IPC分类号： A61K9/08 ,  A61K31/00 ,  A61K31/57 ,  A61K31/573 ,  A61K47/36 ,  A61K47/40 ,  A61K47/48 ,  A61P17/00 ,  A61P29/00 ,  A61K31/56

CPC分类号： B82Y5/00 ,  A61K47/48969

摘要： The present invention provides an external therapeutic composition for dermatitis comprising an aqueous solution including a therapeutically effective amount of an adrenal cortical steroid, a cyclodextrin, polysaccharides, and a carrier such as water, prepared by clathrating the adrenal cortical steroid in the cyclodextrin using a homomixer to form a clathrate, and adding the clathrate to an aqueous solution of polysaccharides, while being stirred uniformly, to dissolve the clathrate in the aqueous solution, as well as a method for the treatment of dermatitis in a mammalian subject, which comprises administering to said subject a therapeupically effective amount of the external therapeutic composition for dermatitis described above. The external therapeutic composition for dermatitis according to the present invention is extremely safe and can cure dermatitis such as an atopic dermatitis or the like without side effects.

摘要翻译： 本发明提供了一种外用皮炎治疗组合物，其包含水溶液，其包含治疗有效量的肾上腺皮质类固醇，环糊精，多糖和载体如水，其通过使用均质混合器将环糊精中的肾上腺皮质类固醇包合在环糊精中 以形成包合物，并且在均匀搅拌的同时将包合物加入到多糖的水溶液中，以将包合物溶解在水溶液中，以及在哺乳动物受试者中治疗皮炎的方法，其包括对所述 服用有效量的上述皮炎外用治疗组合物。 根据本发明的用于皮炎的外用治疗组合物是非常安全的，可以治疗诸如特应性皮炎等的皮炎而没有副作用。

公开(公告)号：US5826683A

公开(公告)日：1998-10-27

申请号：US789267

申请日：1997-01-28

申请人： Yukio Murata ,  Hajime Yamada

发明人： Yukio Murata ,  Hajime Yamada

IPC分类号： F16D65/14 ,  F16D65/18 ,  B60L7/00 ,  F16D55/08

CPC分类号： F16D65/18 ,  B60T8/326 ,  B60T8/321 ,  F16D2121/28 ,  F16D2125/10

摘要： A magnetostrictive brake is provided with an electrically-driven actuator for moving friction materials back and forth toward a rotary member by utilizing a magnetostrictive element which extends and contracts by means of magnetostriction, a fluid-type displacement enlarging mechanism which is provided between the magnetostrictive element and the friction materials and used for enlarging the displacement of the magnetostrictive element and transmitting the enlarged displacement to the friction materials, and bias magnetic field applying means for applying a bias magnetic field to the magnetostrictive element.

摘要翻译： 磁致伸缩制动器设置有电驱动致动器，用于通过利用通过磁致伸缩延伸和收缩的磁致伸缩元件使摩擦材料向旋转构件前后移动;流体型位移放大机构，设置在磁致伸缩元件 和摩擦材料，用于扩大磁致伸缩元件的位移并将扩大的位移传递到摩擦材料，以及用于向磁致伸缩元件施加偏置磁场的偏置磁场施加装置。

公开(公告)号：USD325363S

公开(公告)日：1992-04-14

申请号：US454866

申请日：1989-12-20

申请人： Hajime Yamada ,  Shuichi Etoh ,  Munehiro Sugimoto

设计人： Hajime Yamada ,  Shuichi Etoh ,  Munehiro Sugimoto

公开(公告)号：US4461142A

公开(公告)日：1984-07-24

申请号：US366907

申请日：1982-04-09

申请人： Osamu Nagata ,  Satoru Matsukura ,  Hajime Yamada ,  Yozo Sasaki

发明人： Osamu Nagata ,  Satoru Matsukura ,  Hajime Yamada ,  Yozo Sasaki

IPC分类号： C21B9/00 ,  C21B7/00 ,  F02C1/00 ,  F02C1/05 ,  F02C6/00 ,  F02C9/16 ,  F02C9/18

CPC分类号： F02C1/05 ,  C21B7/002 ,  C21B7/007 ,  F02C9/18

摘要： A method of recovery of furnace gas energy for use to recover excess gas energy from a single or a plurality of furnace gas energy recovering plants each including an expansion turbine mounted in each exhaust system of each blast furnace. In one embodiment, excess gas beyond the power of the respective expansion turbine to recover is removed from each exhaust system of each blast furnace concerned through a branch line, and the removed excess gas is introduced into another expansion turbine through a pressure control valve, to thereby recover the energy possessed by the excess gas. In another embodiment, excess gas is removed through a branch line from each exhaust system of each plant having excess gas beyond the power of the respective expansion turbine to recover mounted in each blast furnace, and the removed excess gas is introduced through a pressure control valve and a flow distribution valve into at least one plant having reserve in the furnace gas energy recovering capacity to thereby recover the energy possessed by the excess gas.The pressure control valve is regulated by pressure control valve regulating means having the functions of furnace gas pressure control and backflow prevention.

摘要翻译： 一种回收炉气能量的方法，用于从单个或多个炉煤气能量回收装置回收多余的气体能量，每个炉气能量回收装置包括安装在每个高炉的每个排气系统中的膨胀涡轮机。 在一个实施例中，通过分支管线从超过相应的膨胀涡轮机的功率超过相应膨胀涡轮机的功率的过剩气体通过分支管路从每个相关高炉的排气系统中排除，并且将去除的过量气体通过压力控制阀引入另一个膨胀涡轮机， 从而回收多余气体所具有的能量。 在另一个实施方案中，通过分支管线将多余的气体从具有超过相应膨胀涡轮机的功率的过量气体的每个设备的每个排气系统移除，以恢复安装在每个高炉中，并且将去除的过量气体通过压力控制阀 以及流量分配阀，其进入至少一个具有炉内气体能量回收能力的设备，从而回收过量气体所具有的能量。 压力控制阀由具有炉内气体压力控制和回流防​​止功能的压力调节阀调节装置调节。

公开(公告)号：US20150022465A1

公开(公告)日：2015-01-22

申请号：US13945491

申请日：2013-07-18

申请人： Hajime Yamada

发明人： Hajime Yamada

IPC分类号： G06F3/0481

CPC分类号： G06F3/04817 ,  B60K35/00 ,  B60K37/06 ,  B60K2370/1438 ,  B60K2370/158 ,  G06F3/0488 ,  G06F2203/04809

摘要： One or more embodiments of techniques or systems for user to vehicle interaction are provided herein. A touchpad can include sensing areas and contoured edges. The sensing areas and contoured edges can be configured to receive inputs. These inputs can be routed to user interface (UI) applications. Additionally, aspects of the UI application can be displayed. Because portions of the touchpad can be contoured, a user or driver can keep their eyes on the road while operating the vehicle, rather than looking away from the windshield or road toward an instrument display. In one or more embodiments, hints related to one or more of the UI applications can be provided to alert a user that potential inputs may be used or that additional features may be available. In this manner, safer driving may be promoted by mitigating how often a driver looks away from the road.

摘要翻译： 本文提供用于用户到车辆交互的技术或系统的一个或多个实施例。 触摸板可以包括感测区域和轮廓边缘。 传感区域和轮廓边缘可配置为接收输入。 这些输入可以路由到用户界面（UI）应用程序。 另外，可以显示UI应用的各个方面。 因为触摸板的部分可以是轮廓，所以在操作车辆时，用户或驾驶员可以将他们的眼睛保持在道路上，而不是远离挡风玻璃或道路朝向仪器显示。 在一个或多个实施例中，可以提供与一个或多个UI应用相关的提示，以提醒用户潜在的输入可以被使用或附加的特征可能是可用的。 以这种方式，可以通过减轻驾驶员从道路上远离的频率来促进更安全的驾驶。

公开(公告)号：US08667537B2

公开(公告)日：2014-03-04

申请号：US13122688

申请日：2009-10-05

申请人： Toshinori Shimizu ,  Ryuhsuke Watanabe ,  Hajime Yamada

发明人： Toshinori Shimizu ,  Ryuhsuke Watanabe ,  Hajime Yamada

IPC分类号： H04N5/445 ,  H04N7/173

CPC分类号： H04N21/435 ,  H04N7/17318 ,  H04N21/235 ,  H04N21/4305 ,  H04N21/4345 ,  H04N21/4432 ,  H04N21/6405 ,  H04N21/64322

摘要： Upon start of processing, a digital broadcast receiver can acquire a CDN configuration information file (XML) after newly connected to a CDN by a user's operation. Next, the digital broadcast receiver acquires a PF configuration information file written in the CDN configuration information. The digital broadcast receiver judges whether there is an IP broadcast or not. If there is an IP broadcast, the digital broadcast receiver connects to a multicast address described in the PF configuration information file (XML), and acquires information on all channels in the PF from a SI dedicated stream (all station SI including no video or audio) (channel scan). The URL of a SNTP is described in the CDN configuration information file. Time information is acquired through the SNTP at the same time as (or at a timing near the timing of, such as immediately before or immediately after) the channel scan. The above processing enables easy time acquisition which is a problem peculiar to an IPTV with which viewing of an IP broadcast is possible.

摘要翻译： 在处理开始时，数字广播接收机可以通过用户的操作获得新连接到CDN之后的CDN配置信息文件（XML）。 接下来，数字广播接收器获取写入CDN配置信息的PF配置信息文件。 数字广播接收机判断是否有IP广播。 如果存在IP广播，则数字广播接收机连接到PF配置信息文件（XML）中描述的多播地址，并且从SI专用流（包括没有视频或音频的所有站SI）获取关于PF中的所有信道的信息 ）（通道扫描）。 CDN配置信息文件中描述了SNTP的URL。 在信道扫描的同时（或者在紧邻或紧随其后的定时附近的时刻）通过SNTP获取时间信息。 上述处理使得能够容易地进行时间获取，这是可以观看IP广播的IPTV所特有的问题。

公开(公告)号：US20140011823A1

公开(公告)日：2014-01-09

申请号：US14005046

申请日：2012-03-13

申请人： Toru Miura ,  Seiichi Sato ,  Hajime Yamada ,  Junya Tagashira ,  Toshiaki Watanabe ,  Ryohei Sekimoto ,  Rie Ishida ,  Hitomi Aoki ,  Tadaaki Ohgiya

发明人： Toru Miura ,  Seiichi Sato ,  Hajime Yamada ,  Junya Tagashira ,  Toshiaki Watanabe ,  Ryohei Sekimoto ,  Rie Ishida ,  Hitomi Aoki ,  Tadaaki Ohgiya

IPC分类号： C07D413/14 ,  C07D401/14

CPC分类号： C07D413/14 ,  A61K31/506 ,  C07D401/14

摘要： The present invention provides: a compound represented by general formula (I) below, that has both angiotensin II receptor antagonism and a PPARγ activation effect and that is useful as a preventative and/or therapeutic agent for high blood pressure, cardiac disease, arteriosclerosis, type-2 diabetes, and the like; and a drug composition containing the compound. General formula (I) (in the formula: ring A represents a pyridine ring; ring B represents a tetrazole ring or an oxadiazol-5(4H)-one ring; X represents C—R5 or a nitrogen atom; R1 represents an alkyl group; R2 represents an alkyl group or a cycloalkyl group; and R3, R4, and R5 each independently represents a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group or similar.

摘要翻译： 本发明提供：下述通式（I）表示的化合物，既具有血管紧张素II受体拮抗作用又具有PPARγ活化作用，可用作高血压，心脏病，动脉硬化等的预防和/或治疗剂， 2型糖尿病等; 和含有该化合物的药物组合物。 通式（I）（式中，环A表示吡啶环;环B表示四唑环或恶二唑-5（4H） - 酮环; X表示C-R5或氮原子; R1表示烷基 ; R 2表示烷基或环烷基; R 3，R 4和R 5各自独立地表示氢原子，卤素原子，烷基，烷氧基等。