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195 条记录 (耗时 0.029 秒)

    Copolymers of lactide and/or glycolide with 1,5-dioxepan-2-one
    34.
    发明授权
    Copolymers of lactide and/or glycolide with 1,5-dioxepan-2-one 失效
    丙交酯和/或乙交酯与1,5-二氧杂环庚烷-2-酮的共聚物

    公开(公告)号：US4470416A

    公开(公告)日：1984-09-11

    申请号：US505160

    申请日：1983-06-17

    申请人： Adel Kafrawy ,  Frank V. Mattei ,  Shalaby W. Shalaby

    发明人： Adel Kafrawy ,  Frank V. Mattei ,  Shalaby W. Shalaby

    IPC分类号： A61L17/12 ,  A61L17/14 ,  A61L27/18 ,  C08G63/664 ,  A61L17/00 ,  C08G63/08

    CPC分类号： C08G63/664 ,  A61L17/12 ,  A61L17/145 ,  A61L27/18

    摘要： Copolymers are prepared from 1,5-dioxepan-2-one and lactide and/or glycolide. The copolymers are useful in surgical applications such as sutures, suture lubricants, and allied surgical products. 1,5-Dioxepan-2-one is produced by a new process comprising first reacting ethylene glycol with an alkyl acrylate to form alkyl 3-(2-hydroxyethoxy)propionate, which is then cyclized by contacting with a trans-esterification catalyst.

    摘要翻译： 共聚物由1,5-二氧杂环庚烷-2-酮和丙交酯和/或乙交酯制备。 共聚物可用于外科应用，例如缝合线，缝线润滑剂和相关的手术产品。 通过包括首先使乙二醇与丙烯酸烷基酯反应形成3-（2-羟基乙氧基）丙酸烷基酯的新工艺生产1,5-二氧杂环庚烷-2-酮，然后通过与酯交换催化剂接触使其环化。

    Synthetic absorbable surgical devices of poly(alkylene oxalates)
    36.
    发明授权
    Synthetic absorbable surgical devices of poly(alkylene oxalates) 失效
    聚（亚烷基草酸盐）的合成可吸收外科手术装置

    公开(公告)号：US4140678A

    公开(公告)日：1979-02-20

    申请号：US806048

    申请日：1977-06-13

    申请人： Shalaby W. Shalaby ,  Dennis D. Damiolkowski

    发明人： Shalaby W. Shalaby ,  Dennis D. Damiolkowski

    IPC分类号： A61L17/10 ,  A61L27/18 ,  C08G63/16 ,  D01F6/62 ,  D01F6/84 ,  C08G63/12

    CPC分类号： D01F6/84 ,  A61L17/105 ,  A61L27/18 ,  C08G63/16 ,  D01F6/625 ,  Y10S623/926

    摘要： Synthetic filaments composed of homopolymers and copolymers of poly(alkylene oxalates) are absorbable in animal tissue with minimal adverse tissue reaction. Polymers prepared by reacting a dialkyl oxalate with an alkylene diol are melt spun and drawn to obtain oriented fibers having good tensile properties and a high level of flexibility and softness. The filaments are particularly useful in the preparation of surgical prosthesis comprising woven or knitted fabrics and meshes. Other absorbable surgical devices including films and molded items may also be prepared from the disclosed polymer.

    摘要翻译： 由聚（亚烷基草酸酯）的均聚物和共聚物组成的合成长丝在动物组织中是可吸收的，具有最小的不利组织反应。 通过使草酸二烷基酯与亚烷基二醇反应制备的聚合物被熔融纺丝并拉伸，得到具有良好拉伸性能和高柔性和柔软度的取向纤维。 长丝在制备包含织造或针织织物和网眼的手术假体中特别有用。 其它可吸收外科装置，包括膜和模制品也可以由所公开的聚合物制备。

    Selectively absorbable/biodegradable, fibrous composite constructs and applications thereof
    39.
    发明授权
    Selectively absorbable/biodegradable, fibrous composite constructs and applications thereof 有权
    选择性吸收/可生物降解的纤维复合结构及其应用

    公开(公告)号：US09011439B2

    公开(公告)日：2015-04-21

    申请号：US11983321

    申请日：2007-11-08

    申请人： Shalaby W. Shalaby ,  Shawn Peniston ,  Kimberly A. Carpenter

    发明人： Shalaby W. Shalaby ,  Shawn Peniston ,  Kimberly A. Carpenter

    IPC分类号： A61B17/04 ,  A61B17/56 ,  A61L27/48 ,  A61L27/58 ,  C08L23/06

    CPC分类号： A61L27/48 ,  A61L27/54 ,  A61L27/58 ,  C08L23/06 ,  C08L2203/12 ,  C08L67/04

    摘要： A family of selectively absorbable/biodegradable, fibrous composite constructs includes different combinations of biostable and absorbable/biodegradable yarns assembled as initially interdependent, load-bearing components, transitioning to exhibit independent functional properties during in vivo end-use. The family of constructs consists of two groups, one group is made of fiber-reinforced composites of high compliance, absorbable matrices of segmented polyaxial copolyesters reinforced with multifilament yarn constructs, which are combinations of ultrahigh molecular weight polyethylene fibers and at least one absorbable/biodegradable fiber selected from silk fibers and multifilament yarns made from linear segmented, l-lactide copolyesters and poly (3-hydroxyalkanoates, are useful in orthopedic, maxillofacial, urological, vascular, hernial repair and tissue engineering applications. The second group is made of coated and uncoated, warp-knitted mesh constructs for use in hernial, vascular, and urological tissue repair and tissue engineering.

    摘要翻译： 一系列可选择性吸收/可生物降解的纤维复合材料构造包括生物稳定和可吸收/可生物降解的纱线的不同组合，其组装为最初相互依赖的承载组分，在体内最终用途中转变为显示独立的功能特性。 构建体组由两组组成，一组由高柔顺性的纤维增强复合材料制成，由多丝纱构造物增强的分段多轴共聚酯的可吸收基质，其是超高分子量聚乙烯纤维和至少一种可吸收/可生物降解的组合 纤维选自由线性分段的丙交酯共聚酯和聚（3-羟基链烷酸酯）制成的丝纤维和复丝纱，可用于矫形，颌面，泌尿，血管，疝修补和组织工程应用中，第二组由涂层和 用于疝，血管和泌尿组织修复和组织工程的无涂层，经编网眼构造物。