公开(公告)号：US06319188B1

公开(公告)日：2001-11-20

申请号：US09299304

申请日：1999-04-26

申请人： Paul A. Lovoi

发明人： Paul A. Lovoi

IPC分类号： A61N500

CPC分类号： A61N5/1001 ,  A61N2005/1022 ,  H01J35/32 ,  H01J2235/164

摘要： A vascular X-ray probe is formed of an optical fiber cable with a high voltage conductor embedded in the optical fiber and an external ground coating, feeding power to a small X-ray tube at the end of the cable. The optical fiber provides a conduit for optical radiation, preferably a laser beam, fed to a thermionic cathode mounted at the end of the light path, so that the laser beam heats the cathode causing it to emit electrons. An anode/X-ray target is opposite the cathode within the evacuated X-ray tube, and the ground lead is fed to the anode via an external ground coating over the tube. The X-ray tube is in preferred embodiments is less than 3 mm in diameter, and more preferably about 1.5 mm. In one embodiment the tube is formed directly in the end of the optical fiber cable, with the anode mounted on an exit window.

摘要翻译： 血管X射线探针由具有嵌入在光纤中的高压导体的光纤电缆和外部地面涂层形成，向电缆端部的小X射线管供电。 该光纤提供用于光辐射的导管，优选地，激光束被馈送到安装在光路端部的热离子阴极，使得激光束加热阴极而使其发射电子。 阳极/ X射线靶与真空X射线管内的阴极相对，并且接地引线通过管上的外部地面涂层进入阳极。 在优选实施例中，X射线管直径小于3mm，更优选约1.5mm。 在一个实施例中，管直接形成在光纤电缆的端部，阳极安装在出口窗口上。

公开(公告)号：US5686790A

公开(公告)日：1997-11-11

申请号：US81913

申请日：1993-06-22

申请人： Christopher J. Curtin ,  Anthony P. Schmid ,  Paul A. Lovoi

发明人： Christopher J. Curtin ,  Anthony P. Schmid ,  Paul A. Lovoi

IPC分类号： G02F1/133 ,  G02F1/1333 ,  G02F1/13357 ,  G02F1/1362 ,  H01J5/04 ,  H01J9/24 ,  H01J29/86 ,  H01J61/30 ,  H01J63/00 ,  H01J63/06 ,  H01J1/30

CPC分类号： G02F1/1333 ,  G02F1/133617 ,  G02F1/1362 ,  H01J29/863 ,  H01J5/04 ,  H01J61/302 ,  H01J63/00 ,  H01J63/06 ,  H01J9/241 ,  G02F2001/133302 ,  G02F2001/133374 ,  H01J2329/00

摘要： According to the invention, a flat panel device includes a faceplate, a backplate made of a co-fired ceramic substrate and attached to the faceplate to form a sealed enclosure, and structure for producing light. The faceplate includes an active region. The light producing structure is divided into a matrix of "display elements," or a plurality of "light producing elements." Driver circuitry is formed on or attached to a surface of the backplate. The driver circuitry is connected to the display elements or light producing elements by electrically conductive vias formed entirely or partially through or within the ceramic substrate, and electrically conductive traces formed within or on one or more surfaces of the ceramic substrate. Each of the display elements or light producing elements is controlled by the driver circuitry to cause light emission at a corresponding pixel or pixels of the faceplate active region.

摘要翻译： 根据本发明，平板装置包括面板，由共烧陶瓷基板制成的背板，并附接到面板以形成密封外壳，以及用于产生光的结构。 面板包括一个活动区域。 光产生结构分为“显示元件”或多个“发光元件”的矩阵。 驱动器电路形成在背板的表面上或附着于背板的表面上。 驱动器电路通过完全或部分地穿过陶瓷衬底或陶瓷衬底内的导电通孔连接到显示元件或发光元件，以及形成在陶瓷衬底的一个或多个表面内或之上的导电迹线。 显示元件或发光元件中的每一个由驱动器电路控制，以在面板有源区域的相应像素或像素处引起发光。

公开(公告)号：US5667418A

公开(公告)日：1997-09-16

申请号：US449036

申请日：1995-05-24

申请人： Theodore S. Fahlen ,  Robert M. Duboc, Jr. ,  Paul A. Lovoi

发明人： Theodore S. Fahlen ,  Robert M. Duboc, Jr. ,  Paul A. Lovoi

IPC分类号： H01J3/02 ,  H01J9/14 ,  H01J9/18 ,  H01J17/49 ,  H01J29/02 ,  H01J29/08 ,  H01J29/46 ,  H01J31/12 ,  H01J61/30 ,  H01J9/26

CPC分类号： H01J61/30 ,  H01J17/49 ,  H01J29/028 ,  H01J29/085 ,  H01J29/467 ,  H01J3/022 ,  H01J31/123 ,  H01J31/126 ,  H01J31/127 ,  H01J9/14 ,  H01J9/185 ,  H01J2329/8625 ,  H01J2329/863 ,  H01J2329/864 ,  H01J2329/8645 ,  Y10S264/91

摘要： A flat panel device is provided with an internal support structure in the form of a spacer. In one fabrication technique, the spacer is formed as a laminate of multiple layers of ceramic, glass-ceramic, ceramic-reinforced glass, devitrified glass, or/and metal coated with electrically insulating material. The spacer is placed between a backplate structure and a faceplate structure which are connected together to form an enclosure that encases the spacer. In another fabrication technique, the spacer constitutes a spacer wall placed between the backplate and faceplate structures. When the backplate structure is connected to the faceplate structure to form an enclosure that encases the spacer wall, the spacer wall follows a corrugated path adjacent to at least one of the faceplate and backplate structures.

摘要翻译： 平板装置设置有间隔件形式的内部支撑结构。 在一种制造技术中，间隔件形成为多层陶瓷，玻璃陶瓷，陶瓷增强玻璃，失透玻璃，或/和涂覆有电绝缘材料的金属的叠层。 间隔件放置在背板结构和面板结构之间，所述背板结构和面板结构连接在一起以形成包围间隔件的外壳。 在另一种制造技术中，间隔件构成放置在背板和面板结构之间的间隔壁。 当背板结构连接到面板结构以形成围绕间隔壁的外壳时，间隔壁遵循邻近面板和背板结构中的至少一个的波纹路径。

公开(公告)号：US4986664A

公开(公告)日：1991-01-22

申请号：US180208

申请日：1988-04-11

申请人： Paul A. Lovoi

发明人： Paul A. Lovoi

IPC分类号： B23K7/06 ,  B23K26/03 ,  B23K26/36 ,  B23K26/40 ,  G01N21/25 ,  G01N21/55

CPC分类号： B23K26/032 ,  B23K26/40 ,  B23K26/402 ,  G01N21/25 ,  B23K2201/35 ,  B23K2203/30 ,  B23K2203/52 ,  B23K7/06 ,  G01N21/55

摘要： A method and apparatus for controlling the milling of an ablatable material and the like from substrate is disclosed. Embodiments for controlling the milling of ablatable materials and the like by pulses of high intensity radiant energy are described. The control process is accomplished by generating an electronic signal representative of the substrate surface topology through use of a structured light or other three dimensional mapping system and feeding the signal to a system control unit. By applying pre-programmed criteria regarding the final desired surface to the generated electronic signal, an electronic reference signal indicative of the dimensional coordinates of the final desired surface may be generated. An ablatable coating is then applied to a height sufficiently above the final desired surface to permit a milling off of the excess coating to produce the desired final surface topology. In the milling process the mapping system is used as a real-time feedback control mechanism for directing a laser. By scanning the surface ahead of the laser, the mapping system generates a new electronic signal representative of the coated surface topology, and this signal is compared to the desired-topology reference signal. At each spot where the comparison indicates the coated surface is above the final desired surface, the controller will order the laser to fire upon that spot, and this is reiterated until the surface features fall within the prescribed limits.

摘要翻译： 公开了一种用于控制可烧蚀材料等从衬底的研磨的方法和装置。 描述了通过高强度辐射能的脉冲控制可烧蚀材料等的研磨的实施例。 通过使用结构光或其他三维映射系统生成表示衬底表面拓扑的电子信号并将信号馈送到系统控制单元来实现控制过程。 通过对所生成的电子信号应用关于最终所需表面的预编程标准，可以产生指示最终期望表面的尺寸坐标的电子参考信号。 然后将可烧蚀的涂层施加到足够高于最终所需表面的高度，以允许磨掉多余的涂层以产生所需的最终表面拓扑。 在铣削过程中，映射系统被用作用于引导激光器的实时反馈控制机构。 通过扫描激光前的表面，映射系统产生代表涂覆表面拓扑的新电子信号，并将该信号与期望拓扑参考信号进行比较。 在比较表明涂层表面高于最终所需表面的每个点处，控制器将命令激光在该点上点燃，并且重复这一点，直到表面特征落入规定限度内。

公开(公告)号：US09022914B2

公开(公告)日：2015-05-05

申请号：US13251014

申请日：2011-09-30

申请人： James E. Clayton ,  Paul A. Lovoi

发明人： James E. Clayton ,  Paul A. Lovoi

IPC分类号： A61N5/00 ,  G21K1/02 ,  H05H15/00 ,  A61N5/10 ,  G21K1/00

CPC分类号： G21K1/025 ,  A61N5/1001 ,  A61N5/1017 ,  A61N5/103 ,  A61N5/1067 ,  A61N5/1071 ,  A61N2005/1022 ,  A61N2005/1088 ,  A61N2005/1089 ,  A61N2005/109 ,  G21K1/00 ,  H05H15/00

摘要： A laser accelerator driven electronic brachytherapy system, device, and method for particle based treatment of a tumor or other human diseases and conditions.

摘要翻译： 激光加速器驱动的电子近距离放射治疗系统，装置和方法，用于基于颗粒的治疗肿瘤或其他人类疾病和病症。

公开(公告)号：US08262555B2

公开(公告)日：2012-09-11

申请号：US11932974

申请日：2007-10-31

申请人： James E. Jervis ,  Paul A. Lovoi

发明人： James E. Jervis ,  Paul A. Lovoi

IPC分类号： A61N5/00

CPC分类号： A61N5/1015 ,  A61N5/103 ,  A61N5/1048

摘要： Radiation treatment methods for breast cancer following resection, both intraoperative and post operative, involve mapping preferably using an electronic x-ray source, and can include rotation of a direction source. By using a very rapid, near-instantaneous method of pathology of tissue margins following resection, the invention carries out intraoperative radiation treatment, preferably with the patient remaining anesthetized. Whether or not radiation is intraoperative, the invention preferably includes a mapping procedure using an electronic source that is progressed through the resection cavity while radiation dose is sensed at one or more points, to determine the shape of the resection cavity.

摘要翻译： 切除术后，术中和术后两者的乳腺癌的放射治疗方法都涉及优选使用电子X射线源进行测绘，并且可包括方向源的旋转。 通过使用切除术后组织边缘的非常快速，近瞬时的病理学方法，本发明进行术中放射治疗，优选在患者保持麻醉的情况下进行。 无论辐射是否在术中，本发明优选地包括使用电子源的映射程序，该电子源在一个或多个点处感测放射剂量时进入切除腔，以确定切除腔的形状。

公开(公告)号：US07727137B2

公开(公告)日：2010-06-01

申请号：US11871116

申请日：2007-10-11

申请人： Darius Francescatti ,  David J. Hoffmann ,  Scott Tremberth ,  Michael Klein ,  Paul A. Lovoi ,  James E. Jervis

发明人： Darius Francescatti ,  David J. Hoffmann ,  Scott Tremberth ,  Michael Klein ,  Paul A. Lovoi ,  James E. Jervis

IPC分类号： A61M36/00 ,  A61M36/04 ,  A61N5/00

CPC分类号： A61N5/1015 ,  A61M2025/1063

摘要： Methods and applicator apparatus are disclosed for brachytherapy treatment of tissue surrounding a cavity in a patient, particularly a resection cavity. In treatment regimes requiring recovery time between successive radiation treatments, applicators of the invention are retained under the skin, with the skin allowed to at least partially heal, and are re-accessed later for one or more subsequent treatments. To reduce patient discomfort an anesthetic agent can be infused through the applicator to patient tissue, for insertion, balloon inflation or removal of the applicator.

摘要翻译： 公开了用于近距离放射治疗患者，特别是切除腔中的腔周围的组织的方法和施用装置。 在需要在连续辐射治疗之间恢复时间的治疗方案中，本发明的施用器保留在皮肤下，允许皮肤至少部分愈合，并且稍后重新进行一次或多次随后的治疗。 为了减少患者的不适，麻醉剂可以通过施用器输注到患者组织，用于插入，球囊充气或去除涂抹器。

公开(公告)号：US07678040B2

公开(公告)日：2010-03-16

申请号：US11809836

申请日：2007-05-31

申请人： Darius Francescatti ,  Paul A. Lovoi

发明人： Darius Francescatti ,  Paul A. Lovoi

IPC分类号： A61N5/00

CPC分类号： A61N5/1016

摘要： A customized gynecological brachytherapy applicator is formed by placing a molded balloon, which is secured to a handle, into a vaginal cavity and then filling the mold balloon with a settable liquid material. The material may be an expanding foam or any other form of curable material that becomes solid, rigid or pliable, when set by chemical action, temperature change, oxidation, a curing means such as a light, or other curing regime. The mold balloon can be elastic or inelastic, depending on the degree to which the applicator is to conform its external surfaces to the vaginal contours. One or more lumina are provided in the set filler material to receive a radiation source, with additional lumina optionally provided for purposes such as drainage or administration of therapeutic agents. The applicator may be withdrawn and reinserted into the vagina during treatment, and selected tissues adjacent to the applicator are irradiated in accordance with a radiation prescription.

公开(公告)号：US20100023429A1

公开(公告)日：2010-01-28

申请号：US11404567

申请日：2006-04-13

申请人： Jarie G. Bolander ,  Paul A. Lovoi ,  Teri E. Judelson ,  Geoff A. Zawolkow

发明人： Jarie G. Bolander ,  Paul A. Lovoi ,  Teri E. Judelson ,  Geoff A. Zawolkow

IPC分类号： G06Q10/00 ,  G08B13/14 ,  G06Q50/00 ,  A61B5/00 ,  G06F17/00

CPC分类号： G06Q10/087

摘要： RFID tags of very small size are embedded in products or composed of products in a manufacturing process. The system employs different read and write modes to enable auto-tracking of material, some assembly, assembly and component items through various stages of the manufacturing process. As each item passes special predetermined points in the manufacturing process, the embedded tag is activated and placed in track mode. The tag transmits its ID and a track count representing the number of stations passed. The tag's track count is incremented and the updated track count is stored in non-volatile memory in the tag. The tags can be programmed so that once the count exceeds a predetermined count, a status bit is set in the tag's memory indicating that the item has been completely through the manufacturing process. Thus, the system can determine whether an item or product has been completed. After manufacture the same RFID tag can be used for tracking, inventory and item authentication.

摘要翻译： 非常小尺寸的RFID标签嵌入产品中或由制造过程中的产品组成。 该系统采用不同的读写模式，可以通过制造过程的各个阶段自动跟踪材料，组件，组件和组件。 当每个物品在制造过程中通过特定的预定点时，嵌入的标签被激活并被放置在轨道模式中。 标签发送其ID和表示通过的站数的轨迹计数。 标签的轨道数量增加，更新的轨道数量存储在标签中的非易失性存储器中。 可以对标签进行编程，使得一旦计数超过预定计数，在标签的存储器中设置状态位，指示该项目已经完全通过制造过程。 因此，系统可以确定物品或产品是否已经完成。 制造完成后，可以使用相同的RFID标签进行跟踪，库存和物品认证。

公开(公告)号：US20090299446A1

公开(公告)日：2009-12-03

申请号：US12156129

申请日：2008-05-28

申请人： Paul A. Lovoi ,  Robert G. Walsh

发明人： Paul A. Lovoi ,  Robert G. Walsh

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N1/0551 ,  A61N1/3605

摘要： A cardiac pacemaker, other CRT device or neurostimulator has one or more fine wire leads. Formed of a glass, silica, sapphire or crystalline quartz fiber with a metal buffer cladding, a unipolar lead can have an outer diameter as small as about 300 microns or even smaller. The buffered fibers are extremely durable, can be bent through small radii and will not fatigue even from millions of iterations of flexing. Bipolar leads can include several conductors side by side within a glass/silica fiber, or can be concentric metal coatings in a structure including several fiber layers. An outer protective sheath of a flexible polymer material can be included.

摘要翻译： 心脏起搏器，其他CRT装置或神经刺激器具有一根或多根细线。 由具有金属缓冲包层的玻璃，二氧化硅，蓝宝石或结晶石英纤维形成，单极引线可以具有小至约300微米甚至更小的外径。 缓冲的纤维是非常耐用的，可以弯曲通过小的半径，即使从数百万次的弯曲迭代也不会疲劳。 双极引线可以在玻璃/二氧化硅纤维内并排包括多个导体，或者可以是包括几个纤维层的结构的同心金属涂层。 可以包括柔性聚合物材料的外护套。