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116 条记录 (耗时 0.054 秒)

    Local perfusion device
    32.
    发明授权
    Local perfusion device 有权
    局部灌注装置

    公开(公告)号：US07963940B2

    公开(公告)日：2011-06-21

    申请号：US11208879

    申请日：2005-08-22

    申请人： Thomas J. Holman ,  Jan Weber ,  Tracee Eidenschink

    发明人： Thomas J. Holman ,  Jan Weber ,  Tracee Eidenschink

    IPC分类号： A61M29/00

    CPC分类号： A61F7/12 ,  A61F2007/0063 ,  A61F2007/126

    摘要： A device for providing a fluid to a target tissue region of a body vessel is described. The device includes an elongate member having a lumen to receive a fluid, and a structure deployable from a distal portion of the elongate member to channel blood flowing in the vessel. Also described are a method of, and a system for, providing a fluid to a target tissue region inside a body.

    摘要翻译： 描述了一种用于向身体血管的靶组织区域提供流体的装置。 该装置包括具有用于容纳流体的内腔的细长构件，以及可从细长构件的远侧部分展开以使在血管中流动的血液通道的结构。 还描述了向身体内的靶组织区域提供流体的方法和系统。

    Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power
    35.
    发明申请
    Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power 有权
    用于与电力源一起递送治疗剂的内部医疗装置

    公开(公告)号：US20080262412A1

    公开(公告)日：2008-10-23

    申请号：US12077603

    申请日：2008-03-20

    申请人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    发明人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    IPC分类号： A61N1/30 ,  A61M25/10

    CPC分类号： A61N1/325 ,  A61N1/05 ,  A61N1/306 ,  A61N1/327

    摘要： The invention generally relates to internal (e.g., implantable, insertable, etc.) drug delivery devices which contain the following: (a) one or more sources of one or more therapeutic agents; (b) one or more first electrodes, (c) one or more second electrodes and (d) one or more power sources for applying voltages across the first and second electrodes. The power sources may be adapted, for example, to promote electrically assisted therapeutic agent delivery within a subject, including electroporation and/or iontophoresis. In one aspect of the invention, the first and second electrodes are adapted to have tissue of a subject positioned between them upon deployment of the medical device within the subject, such that an electric field may be generated, which is directed into the tissue. Furthermore, the therapeutic agent sources are adapted to introduce the therapeutic agents into the electric field. In another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of ion-conductive polymers and one or more types of charged therapeutic agents. In yet another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of electrically conductive polymers and one or more types of charged therapeutic agents.

    摘要翻译： 本发明一般涉及含有以下物质的内部（例如，可植入，可插入等）药物递送装置：（a）一种或多种一种或多种治疗剂来源; （b）一个或多个第一电极，（c）一个或多个第二电极和（d）用于在第一和第二电极上施加电压的一个或多个电源。 电源可以适应于例如促进受试者内的电辅助治疗剂递送，包括电穿孔和/或离子电渗疗法。 在本发明的一个方面中，第一和第二电极适于在医疗装置在受试者内展开时使被检体的组织位于它们之间，使得可以产生被引导到组织中的电场。 此外，治疗剂源适于将治疗剂引入电场。 另一方面，治疗剂来源是含有一种或多种类型的离子导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。 在另一方面，治疗剂来源是含有一种或多种类型的导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。

    Memory module having a memory controller to interface with a system bus
    37.
    发明授权
    Memory module having a memory controller to interface with a system bus 有权
    存储器模块具有与系统总线接口的存储器控​​制器

    公开(公告)号：US07240145B2

    公开(公告)日：2007-07-03

    申请号：US11365295

    申请日：2006-02-28

    申请人： Thomas J. Holman

    发明人： Thomas J. Holman

    IPC分类号： G06F12/00

    CPC分类号： G11C5/04 ,  G06F13/1689 ,  G06F13/1694 ,  G11C5/00 ,  G11C5/025

    摘要： A memory module includes a memory module controller to be coupled to a system memory controller by a system memory bus and a plurality of memory devices coupled to the memory module controller, where signaling between the memory module controller and one or more of the memory devices is independent of signal loading or operating voltage of the system memory bus.

    摘要翻译： 存储器模块包括存储器模块控制器，其通过系统存储器总线耦合到系统存储器控制器，以及耦合到存储器模块控制器的多个存储器件，其中存储器模块控制器与一个或多个存储器件之间的信令是 独立于系统存储器总线的信号负载或工作电压。

    Method and apparatus for propagating error status over an ECC protected channel
    39.
    发明授权
    Method and apparatus for propagating error status over an ECC protected channel 有权

    公开(公告)号：US06622268B2

    公开(公告)日：2003-09-16

    申请号：US09725221

    申请日：2000-11-29

    申请人： Thomas J. Holman

    发明人： Thomas J. Holman

    IPC分类号： H03M1303

    CPC分类号： H03M13/03 ,  H03M13/01

    摘要： System and methods for propagating error status over an error checking and correcting (ECC) protected channel. A first device receives data and an error status associated with the data. The first device generates check bits for the data based on a first ECC code and combines the check bits with the data to form one or more code words. The first device sends the code words across the channel where the first device inserts a triple error into a nibble of at least one codeword sent if the error status indicated an uncorrectable error. A second device connected to the channel receives the code words sent across the channel. The second device detects triple errors within a nibble of any code word and any other single error in the code word using a second ECC code, where the second ECC code is the first ECC code with columns for check bits inserted.

    Catheter with removable balloon protector and stent delivery system with removable stent protector
    40.
    发明授权
    Catheter with removable balloon protector and stent delivery system with removable stent protector 有权

    公开(公告)号：US06416529B1

    公开(公告)日：2002-07-09

    申请号：US09528613

    申请日：2000-03-20

    申请人： Thomas J. Holman ,  Louis G. Ellis ,  Gregory K. Olson ,  Linda R. Lorentzen Cornelius ,  Richard J. Traxler ,  Scott M. Hanson ,  Tracee E. J. Eidenschink ,  Sonja J. K. Williams

    发明人： Thomas J. Holman ,  Louis G. Ellis ,  Gregory K. Olson ,  Linda R. Lorentzen Cornelius ,  Richard J. Traxler ,  Scott M. Hanson ,  Tracee E. J. Eidenschink ,  Sonja J. K. Williams

    IPC分类号： A61M2900

    CPC分类号： A61M25/104 ,  A61F2/0095 ,  A61F2/958 ,  A61F2002/9583 ,  A61M2025/1081

    摘要： A balloon catheter is provided having an expandable distal portion and balloon protector means comprising a first removable sleeve having a variable inner diameter to ease sliding the first sleeve over the balloon, and an optional second removable (outer) sleeve positioned over the inner sleeve, the second (outer) sleeve having a constrictive relationship with the first (inner) sleeve, said first and second sleeves being removed prior to use of the catheter. A stent delivery system is provided to facilitate introduction and placement of a stent, and includes a catheter having an expandable distal portion constructed and arranged for expanding the outer diameter of the catheter from a contracted state to an expanded state, said distal portion further comprising a balloon and at least one dam over which the balloon extends, and a stent positioned around the distal portion of the catheter around the balloon or gripper linear control device, said stent having a contracted condition, being sized in the contracted condition to closely surround the balloon in the contracted state, and being expandable to an expanded condition; a first removable (inner) sleeve in the region of the distal portion of the catheter positioned around the stent (and between the damns where the device comprises two dams), said first sleeve comprising a first end, a second end and a variable inner diameter to ease sliding the sleeve over the balloon and stent; an optional second removable (outer) sleeve positioned over the stent, first sleeve and at least one dam, said second (outer) sleeve having a constrictive relationship with the first (inner) sleeve, whereby when compressed by the outer sleeve, the inner sleeve will have an inner diameter approximately equal to or less than the outer profile of the collapsed balloon over the at least one dam, said first and second sleeves being removed prior to use of the stent delivery system and release of the stent by expansion of the balloon.