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116 条记录 (耗时 0.061 秒)

    Method of molding Y-adapter with a sideport radius
    31.
    发明授权
    Method of molding Y-adapter with a sideport radius 失效
    Y侧适配器侧边半径成型方法

    公开(公告)号：US5470522A

    公开(公告)日：1995-11-28

    申请号：US273811

    申请日：1994-07-12

    申请人： Scott P. Thome ,  Thomas J. Holman

    发明人： Scott P. Thome ,  Thomas J. Holman

    IPC分类号： A61M39/10 ,  B29C45/36 ,  B29C45/44

    CPC分类号： A61M39/10 ,  A61M2039/1077 ,  A61M2039/1083 ,  Y10S425/058

    摘要： A method of molding the main body of a Y-adapter that has a straight passageway extending from one extremity to the other and an arcuate passageway that is generated along the arc of a circle. Core pins for the straight and arcuate passageways are placed in a mold such that they merges together to form a single, smooth lumen in the Y-adapter. The arcuate core pin can be withdrawn from the finished Y-adapter as a result of its circular arc.

    摘要翻译： 将具有从一个末端延伸到另一个末端的直通道的Y型适配器的主体成型的方法和沿着圆弧产生的弓形通道的方法。 直线和弓形通道的芯针放置在模具中，使得它们合并在一起以在Y适配器中形成单个光滑的内腔。 弓形芯销可以由于其圆弧而从完成的Y型适配器中取出。

    Self locking guide catheter
    32.
    发明授权
    Self locking guide catheter 失效
    自锁导向导管

    公开(公告)号：US5224939A

    公开(公告)日：1993-07-06

    申请号：US888748

    申请日：1992-05-22

    申请人： Thomas J. Holman ,  Henry J. Pepin ,  William H. Penny

    发明人： Thomas J. Holman ,  Henry J. Pepin ,  William H. Penny

    IPC分类号： A61M5/158 ,  A61M25/00 ,  A61M25/088

    CPC分类号： A61M5/158 ,  A61M25/0014 ,  A61M2025/0098 ,  A61M25/0097

    摘要： A guide catheter in which the components of the hub include a ratchet mechanism that is operative to lock the hub components together and compress an integral flange of the catheter shaft therebetween to form a seal between the hub and catheter shaft without the use of bonding agents that will not become loosened accidently or inadvertently.

    摘要翻译： 一种引导导管，其中所述轮毂的部件包括棘轮机构，所述棘轮机构可操作以将所述轮毂部件锁定在一起并将所述导管轴的整体凸缘压缩在其间，以在所述轮毂和导管轴之间形成密封，而不使用粘结剂 不会意外或不经意地松动。

    Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power
    38.
    发明申请
    Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power 有权
    用于与电力源一起递送治疗剂的内部医疗装置

    公开(公告)号：US20080262412A1

    公开(公告)日：2008-10-23

    申请号：US12077603

    申请日：2008-03-20

    申请人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    发明人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    IPC分类号： A61N1/30 ,  A61M25/10

    CPC分类号： A61N1/325 ,  A61N1/05 ,  A61N1/306 ,  A61N1/327

    摘要： The invention generally relates to internal (e.g., implantable, insertable, etc.) drug delivery devices which contain the following: (a) one or more sources of one or more therapeutic agents; (b) one or more first electrodes, (c) one or more second electrodes and (d) one or more power sources for applying voltages across the first and second electrodes. The power sources may be adapted, for example, to promote electrically assisted therapeutic agent delivery within a subject, including electroporation and/or iontophoresis. In one aspect of the invention, the first and second electrodes are adapted to have tissue of a subject positioned between them upon deployment of the medical device within the subject, such that an electric field may be generated, which is directed into the tissue. Furthermore, the therapeutic agent sources are adapted to introduce the therapeutic agents into the electric field. In another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of ion-conductive polymers and one or more types of charged therapeutic agents. In yet another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of electrically conductive polymers and one or more types of charged therapeutic agents.

    摘要翻译： 本发明一般涉及含有以下物质的内部（例如，可植入，可插入等）药物递送装置：（a）一种或多种一种或多种治疗剂来源; （b）一个或多个第一电极，（c）一个或多个第二电极和（d）用于在第一和第二电极上施加电压的一个或多个电源。 电源可以适应于例如促进受试者内的电辅助治疗剂递送，包括电穿孔和/或离子电渗疗法。 在本发明的一个方面中，第一和第二电极适于在医疗装置在受试者内展开时使被检体的组织位于它们之间，使得可以产生被引导到组织中的电场。 此外，治疗剂源适于将治疗剂引入电场。 另一方面，治疗剂来源是含有一种或多种类型的离子导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。 在另一方面，治疗剂来源是含有一种或多种类型的导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。

    Memory module having a memory controller to interface with a system bus
    39.
    发明授权
    Memory module having a memory controller to interface with a system bus 有权
    存储器模块具有与系统总线接口的存储器控​​制器

    公开(公告)号：US07240145B2

    公开(公告)日：2007-07-03

    申请号：US11365295

    申请日：2006-02-28

    申请人： Thomas J. Holman

    发明人： Thomas J. Holman

    IPC分类号： G06F12/00

    CPC分类号： G11C5/04 ,  G06F13/1689 ,  G06F13/1694 ,  G11C5/00 ,  G11C5/025

    摘要： A memory module includes a memory module controller to be coupled to a system memory controller by a system memory bus and a plurality of memory devices coupled to the memory module controller, where signaling between the memory module controller and one or more of the memory devices is independent of signal loading or operating voltage of the system memory bus.

    摘要翻译： 存储器模块包括存储器模块控制器，其通过系统存储器总线耦合到系统存储器控制器，以及耦合到存储器模块控制器的多个存储器件，其中存储器模块控制器与一个或多个存储器件之间的信令是 独立于系统存储器总线的信号负载或工作电压。