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公开(公告)号：US20210315557A1
公开(公告)日：2021-10-14
申请号：US17313150
申请日：2021-05-06
发明人： Erez ILAN , Yotam GURMAN , Moti MERON
IPC分类号： A61B17/00
摘要： The invention relates to a device suitable for application of a curable fluid composition to encircle a bodily organ. The device comprises a monolithic piece of a flexible material having a length dimension with an inner surface and an outer surface, a first end and a second end, a width dimension, and two spaced-apart sides, wherein a portion of the length dimension proximal to the first end is configured to contact a portion of the length dimension proximal to the second end, the inner surface defining a hollow area between the two spaced-apart sides; and at least one inlet providing fluid communication between the outer surface and the inner surface, for introduction of the fluid into the hollow area. The device deployable around the bodily organ such that when the portion of the length dimension proximal to the first end contacts the portion of the length dimension proximal to the second end, an outer surface of the bodily organ and the hollowed area define an enclosed volume encircling the bodily organ, the enclosed volume suitable for containing the fluid therein.
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公开(公告)号：US11123397B2
公开(公告)日：2021-09-21
申请号：US15700655
申请日：2017-09-11
发明人： Tamar Auerbach-Nevo , Ashley Deanglis , Israel Nur
摘要： Provided are pharmaceutical foam compositions comprising a peptone, a peptide hydrolysate or an enzymatically-hydrolyzed protein prepared by enzymatic hydrolysis of a full-length protein; methods of preparation and uses thereof.
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公开(公告)号：US20210228783A1
公开(公告)日：2021-07-29
申请号：US17228432
申请日：2021-04-12
发明人： Eve Montia , Dwayne Looney , Theresa Scheuble , Ronen Eavri , Roi Mashiach
摘要： Disclosed are compositions comprised of Oxidized Cellulose (OC), such as oxidized regenerated cellulose (ORC), and an antibiotic comprised of minocycline, methods of preparation thereof and uses thereof.
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公开(公告)号：US11008560B2
公开(公告)日：2021-05-18
申请号：US15922301
申请日：2018-03-15
发明人： Tamar Auerbach-Nevo , Nadav Orr , Israel Nur
IPC分类号： C12N9/74 , C12Q1/56 , G01N33/49 , C07K14/745 , A61K38/00
摘要： Provided is a method for purifying α-thrombin and for quantifying α-thrombin and its degradation polypeptides in a liquid proteinatious solution. The method employs a one-step anion exchange chromatography method. The method allows purification and/or quantification of a homogenous post-translationally modified α-thrombin. The method can also be used for purification and/or quantification of β-thrombin.
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公开(公告)号：US10466258B2
公开(公告)日：2019-11-05
申请号：US15477692
申请日：2017-04-03
发明人： Elena Grimberg , Roberto Meidler , Yonit Tiberman , Nadav Orr , Nadav Ashkenazy
摘要： Provided is a method, device and system for an in-situ preparation of a sample, for example, for use in detecting the presence of, and/or quantifying, clottable fibrinogen in such a sample.
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公开(公告)号：US10357589B2
公开(公告)日：2019-07-23
申请号：US15467191
申请日：2017-03-23
发明人： Yair Pilpel , Ashley Deanglis , Yuri Zherdev , Sivan Doron , Israel Nur
摘要： Provided herein are stable liquid sealant formulations comprising fibrin monomers and a reversible fibrin polymerization blocking agent, methods of preparing and using the formulations.
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公开(公告)号：US10092695B2
公开(公告)日：2018-10-09
申请号：US14848534
申请日：2015-09-09
发明人： Erez Ilan , Kfir Regev , Yotam Gurman , Robert J. Tannhauser
摘要： The presently disclosed subject matter relates to an addition to a medical applicator in general and in particular to an addition to a medical applicator for applying on a surface a curable liquid substance having multi components.
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公开(公告)号：US10066224B2
公开(公告)日：2018-09-04
申请号：US15051821
申请日：2016-02-24
发明人： Tamar Auerbach-Nevo , Nadav Orr , Israel Nur
IPC分类号： C12Q1/56 , C12N9/74 , G01N33/49 , C07K14/745 , A61K38/00
CPC分类号： C12N9/6429 , A61K38/00 , C07K14/745 , C12Q1/56 , C12Y304/21005 , G01N33/491 , G01N2333/96463
摘要： Provided is a method for purifying α-thrombin and for quantifying α-thrombin and its degradation polypeptides in a liquid proteinatious solution. The method employs a one-step anion exchange chromatography method. The method allows purification and/or quantification of a homogenous post-translationally modified α-thrombin. The method can also be used for purification and/or quantification of β-thrombin.
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公开(公告)号：US09867852B2
公开(公告)日：2018-01-16
申请号：US14134033
申请日：2013-12-19
发明人： Lior Weissman , Itai Podoler , Israel Nur , Tamara Byk-Tennenbaum
CPC分类号： A61K35/19 , A61K38/1825 , A61K38/1858 , A61L2/00 , A61L2/0005 , A61L2/0088 , A61L2202/22
摘要： The invention relates to a viral inactivated biological liquid or dry mixture and to its preparation. Principally, the invention relates, but is not limited, to a mixture derived from a platelet source.
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公开(公告)号：US09211555B2
公开(公告)日：2015-12-15
申请号：US13484616
申请日：2012-05-31
申请人： Moti Meron , Roee Atlas , Assaf Gershonovitch , Amatzia Gantz , John Goodman
发明人： Moti Meron , Roee Atlas , Assaf Gershonovitch , Amatzia Gantz , John Goodman
IPC分类号： B05B7/06 , B05B7/24 , A61B17/00 , B01F5/02 , B01F13/00 , B05B7/08 , A61M11/00 , A61M15/00 , A61M11/02 , A61M35/00
CPC分类号： B05B7/2472 , A61B17/00491 , A61B2017/00495 , A61B2017/00522 , A61M11/00 , A61M11/007 , A61M11/02 , A61M15/0003 , A61M35/003 , B01F5/0262 , B01F13/0023 , B05B7/061 , B05B7/08
摘要： The invention relates to an applicator tip for spraying and/or mixing at least two fluids that react together, the tip comprising: at least two fluid conduits for carrying the at least two fluids, each conduit having at least one outlet opening, the openings are positioned substantially on a same plane; at least two gas conduits for carrying a gas volume, each gas conduit comprises a proximal gas tube and a distal gas tube, each distal gas tube is bent as compared to the position of the proximal gas tube, and each distal gas tube has one gas opening positioned distal from the plane of the outlet openings; and a housing for accommodating the at least two fluid conduits and the at least two gas conduits. The device allows efficient spraying in close proximity to a surface.
摘要翻译： 本发明涉及一种用于喷射和/或混合至少两种反应在一起的流体的施用器尖端，所述尖端包括：用于承载至少两种流体的至少两个流体导管，每个导管具有至少一个出口开口，所述开口是 基本位于同一平面上; 用于承载气体体积的至少两个气体管道，每个气体导管包括近端气体管和远端气体管，每个远端气体管与近侧气体管的位置相比弯曲，并且每个远端气体管具有一个气体 开口位于远离出口开口的平面; 以及用于容纳所述至少两个流体导管和所述至少两个气体导管的壳体。 该装置允许在表面附近有效地喷涂。
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