公开(公告)号：US20190022158A1

公开(公告)日：2019-01-24

申请号：US15451377

申请日：2017-03-06

Applicant: Vireo Health LLC

Inventor： Eric Greenbaum ,  Kyle Kingsley

IPC: A61K36/185 ,  A61K31/047 ,  A61K31/352 ,  A24D3/14 ,  A24D1/00 ,  A24B3/12 ,  A24B15/30

CPC classification number: A61K36/185 ,  A24B3/12 ,  A24B15/302 ,  A24B15/303 ,  A24D1/002 ,  A24D3/14 ,  A61K31/047 ,  A61K31/352 ,  A61K2236/37 ,  A61K2236/39

Abstract: A substantially pure fraction of at least one cannabinoid is added to smokable or smokeless tobacco products to reduce the harm associated with tobacco use. The harm to be reduced includes irritation and carcinogenicity of tobacco. In a preferred embodiment a whole plant cannabis extract is mixed directly with the tobacco during the curing or manufacturing process. For cigarette applications the cannabinoids may be inserted into a cigarette filter, and/or paper. In other embodiments the cannabinoids are purified.

公开(公告)号：US20180263277A1

公开(公告)日：2018-09-20

申请号：US15988004

申请日：2018-05-24

Applicant: R.J. REYNOLDS TOBACCO COMPANY

Inventor： Daniel Verdin Cantrell ,  Gong Chen ,  Matthew William Benford ,  Thaddeus Jude Jackson

IPC: A24B15/30 ,  A24B15/24 ,  A24B13/00 ,  A23G4/06 ,  A61K9/00 ,  A23G1/36 ,  A23G3/40 ,  A23G1/48 ,  A23G3/48

CPC classification number: A24B15/303 ,  A23G1/36 ,  A23G1/48 ,  A23G3/40 ,  A23G3/48 ,  A23G4/068 ,  A24B13/00 ,  A24B15/24 ,  A24B15/30 ,  A24B15/302 ,  A61K9/0056

Abstract: A meltable smokeless tobacco composition configured for insertion into the mouth of a user is provided. The smokeless tobacco composition includes a tobacco material and a lipid having a melting point of about 36° C. to about 45° C. An associated process is also provided. The process includes melting a lipid having a melting point of about 36° C. to about 45° C. to form a molten lipid composition, mixing a tobacco material with the molten lipid composition to form a molten smokeless tobacco composition, and cooling the molten smokeless tobacco composition to form a solidified smokeless tobacco composition.

公开(公告)号：US20180255834A1

公开(公告)日：2018-09-13

申请号：US15760139

申请日：2016-09-16

Applicant: Alexandra DILLMANN

Inventor： Alexandra DILLMANN ,  Katharina BIZU

IPC: A24F47/00 ,  A24B15/16 ,  A24B15/30 ,  A24B15/34 ,  A24B15/32 ,  A24B15/38 ,  A24B15/42 ,  A24B15/40 ,  A61K31/07 ,  A61K31/51 ,  A61K31/375 ,  A61K31/355 ,  A61K31/593 ,  A61K31/455 ,  A61K31/519 ,  A61K31/4188 ,  A61K31/198 ,  A61K33/04 ,  A61K33/30 ,  A61K31/525 ,  A61K31/4415 ,  A61K31/714 ,  A61K31/205 ,  A61K31/197 ,  A61K33/06 ,  A61K31/202 ,  A61K31/122 ,  A61K31/05 ,  A61K38/39 ,  A61K36/185 ,  A61K36/8945 ,  A61K31/5685 ,  A61K31/728 ,  A61K31/661 ,  A61K33/00 ,  A61K31/133 ,  A61K36/16 ,  A61K36/324 ,  A61K36/87 ,  A61K36/889 ,  A61K36/77 ,  A61K31/522 ,  A61M11/04 ,  A61M15/06

CPC classification number: A24F47/008 ,  A24B15/167 ,  A24B15/30 ,  A24B15/301 ,  A24B15/302 ,  A24B15/303 ,  A24B15/308 ,  A24B15/32 ,  A24B15/345 ,  A24B15/38 ,  A24B15/385 ,  A24B15/403 ,  A24B15/406 ,  A24B15/42 ,  A24F47/004 ,  A61K31/05 ,  A61K31/07 ,  A61K31/122 ,  A61K31/133 ,  A61K31/197 ,  A61K31/198 ,  A61K31/202 ,  A61K31/205 ,  A61K31/355 ,  A61K31/375 ,  A61K31/4188 ,  A61K31/4415 ,  A61K31/455 ,  A61K31/51 ,  A61K31/519 ,  A61K31/522 ,  A61K31/525 ,  A61K31/5685 ,  A61K31/593 ,  A61K31/661 ,  A61K31/714 ,  A61K31/728 ,  A61K33/00 ,  A61K33/04 ,  A61K33/06 ,  A61K33/30 ,  A61K36/16 ,  A61K36/185 ,  A61K36/324 ,  A61K36/77 ,  A61K36/87 ,  A61K36/889 ,  A61K36/8945 ,  A61K38/39 ,  A61M11/042 ,  A61M15/06 ,  A61M2205/3653 ,  A61M2205/8206

Abstract: The present invention relates to a dispensing arrangement (1), or to an e-cigarette (100) containing such a dispensing arrangement, for treating a flow of vaporized liquid provided via a flow channel (3) of an e-cigarette, comprising a dispensing unit (10) for adding an additional composition into the flow of vaporized liquid of the e-cigarette, and a composition reservoir (2) for retaining the additional composition, wherein the dispensing unit is in communication with a composition reservoir and in communication with the flow channel, wherein the composition reservoir is arranged separately to the flow channel, and wherein the dispensing arrangement is adapted to temper the vaporized liquid and/or the additional composition to a temperature of below 40° C. or below 35° C. before adding the additional composition into the flow of vaporized liquid, as well as methods for the oral intake of compositions, particularly those comprising temperature-sensitive compounds or compounds insoluble in the liquid carrier, such as certain anti-aging compounds, by virtue of an e-cigarette comprising said dispensing arrangement. The present invention also relates to uses of said dispensing arrangement or of an e-cigarette comprising said dispensing arrangement for the oral intake of additional compositions comprising at least one anti-aging compound to a user.

公开(公告)号：US09752174B2

公开(公告)日：2017-09-05

申请号：US14287837

申请日：2014-05-27

Applicant: PURECIRCLE SDN BHD ,  THE COCA-COLA COMPANY

Inventor： Avetik Markosyan ,  Indra Prakash ,  Cynthia Bunders ,  Pankaj Soni ,  Jarrin Cyrille ,  Aurélien Badie ,  Robert ter Halle

IPC: C12P19/56 ,  A23L2/60 ,  A24B15/10 ,  C07H15/256 ,  A24B15/30 ,  A23L27/30

CPC classification number: C12P19/56 ,  A23L2/60 ,  A23L27/33 ,  A23V2002/00 ,  A24B15/10 ,  A24B15/302 ,  C07H15/256 ,  Y02P20/582 ,  A23V2250/258

Abstract: Methods of preparing highly purified steviol glycosides, particularly rebaudiosides A, D and M are described. The methods include utilizing recombinant microorganisms for converting various staring compositions to target steviol glycosides. In addition, novel steviol glycosides reb D2 and reb M2 are disclosed, as are methods of preparing the same. The highly purified rebaudiosides are useful as non-caloric sweetener in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.

公开(公告)号：US20170215471A1

公开(公告)日：2017-08-03

申请号：US15013751

申请日：2016-02-02

Applicant: R.J. Reynolds Tobacco Company

Inventor： Christopher Junker ,  Michael Francis Dube ,  Anthony Richard Gerardi

IPC: A24B15/24 ,  A24B15/30 ,  D21C11/00

CPC classification number: A24B15/241 ,  A24B15/24 ,  A24B15/28 ,  A24B15/287 ,  A24B15/302 ,  D21C11/0007

Abstract: A method of isolating compounds from a tobacco-derived black liquor, including receiving a black liquor from a pulping process of an input material comprising a plant of the Nicotiana species, treating the black liquor with an acid to lower the pH of the black liquor to about 7 or lower in order to produce a precipitate and an acidified black liquor, separating the precipitate and the acidified black liquor, extracting the acidified black liquor with an organic solvent in order to produce an organic layer extract and an aqueous layer extract, and separating the organic layer extract and the aqueous layer extract.

公开(公告)号：US20160316814A1

公开(公告)日：2016-11-03

申请号：US15209981

申请日：2016-07-14

Applicant: R. J. REYNOLDS TOBACCO COMPANY

Inventor： William Monroe Coleman, III ,  Michael Francis Dube ,  Darlene Madeline Lawson

IPC: A24B15/30 ,  C12P13/04 ,  C12P7/22 ,  A24B15/24 ,  C12P7/64

CPC classification number: A24B15/307 ,  A24B15/24 ,  A24B15/302 ,  C12P7/22 ,  C12P7/6409 ,  C12P7/6427 ,  C12P7/6445 ,  C12P13/04

Abstract: A tobacco composition for use in a smoking article or a smokeless tobacco composition is provided, the composition including a component derived from a seed of the Nicotiana species. The component can be a seed of the Nicotiana species or a portion thereof in particulate form or in the form of seed isolate derived from a seed of the Nicotiana species. In certain embodiments, the seed isolate is in the form of a chemically transformed seed isolate, the chemical transformation being selected from hydrogenation, acid/base reaction, hydrolysis, thermal treatment, and enzymatic treatment. The invention also provides smoking articles and smokeless tobacco compositions that include the seed components described herein, and methods for preparing a component derived from a seed of the Nicotiana species for addition to a tobacco composition.

Abstract translation: 提供了用于吸烟制品或无烟烟草组合物的烟草组合物，该组合物包括衍生自烟草属种子的成分。 该组分可以是烟草属物种的种子或其一部分为颗粒形式或以种子分离物的形式来自烟草种子的种子。 在某些实施方案中，种子分离物是化学转化的种子分离物的形式，化学转化选自氢化，酸/碱反应，水解，热处理和酶处理。 本发明还提供了包含本文所述的种子成分的吸烟制品和无烟烟草组合物，以及用于制备衍生自烟草种子的成分的成分的方法，用于添加到烟草组合物中。

公开(公告)号：US20160227834A1

公开(公告)日：2016-08-11

申请号：US15099971

申请日：2016-04-15

Applicant: R. J. REYNOLDS TOBACCO COMPANY

Inventor： Medwick Vaughan Byrd, JR. ,  Paul Stuart Chapman ,  Samuel Mark Debusk ,  Grady Lance Dooly ,  Anthony Richard Gerardi ,  David Neil McClanahan

IPC: A24B15/30 ,  D21C3/02 ,  D21H11/02 ,  D21H11/12 ,  A24B15/24 ,  A24B13/00

CPC classification number: A24B15/302 ,  A24B13/00 ,  A24B15/12 ,  A24B15/241 ,  C08H8/00 ,  C08L1/04 ,  C08L97/02 ,  C09J101/04 ,  D21C3/02 ,  D21H11/02 ,  D21H11/12

Abstract: Methods for producing dissolving grade pulp and microcrystalline cellulose from tobacco are provided. The methods include chemical pulping a tobacco input to form a tobacco pulp. Chemical pulping the tobacco input includes combining the tobacco input with a strong base defining a weight from about 5% to about 50% of the tobacco input, and heating the tobacco input and the strong base with an H-factor from about 500 to about 3,300. Further, the methods include bleaching the tobacco pulp to produce a dissolving grade pulp. Bleaching the tobacco pulp may include chlorination of the tobacco pulp with a chlorine dioxide solution, and caustic extraction of the tobacco pulp with a second strong base. A related tobacco-derived microcrystalline cellulose product is also provided, which can be used as a binder, a filler, and/or a texturizer in a tobacco product, such as a smokeless tobacco product.

公开(公告)号：US20150320107A1

公开(公告)日：2015-11-12

申请号：US14805212

申请日：2015-07-21

Applicant: R.J. Reynolds Tobacco Company

Inventor： Michael Francis Dube ,  William Monroe Coleman, III

IPC: A24B13/00 ,  A24B15/10 ,  A24B15/24

CPC classification number: A24B13/00 ,  A24B15/10 ,  A24B15/24 ,  A24B15/302

Abstract: The invention provides a tobacco composition for use in a smoking article or a smokeless tobacco composition that comprises an extract derived from a component of a plant of the Nicotiana species. The invention also provides smoking articles and smokeless tobacco compositions that include the extracts described herein, and methods for preparing extracts derived from a component of a plant of the Nicotiana species for addition to a tobacco composition.

Abstract translation: 本发明提供一种用于吸烟制品或无烟烟草组合物的烟草组合物，其包含衍生自烟草属植物的组分的提取物。 本发明还提供了包含本文所述提取物的吸烟制品和无烟烟草组合物，以及用于制备来自烟草属植物的组分的提取物的方法，用于添加到烟草组合物中。

公开(公告)号：US20150313276A9

公开(公告)日：2015-11-05

申请号：US13940925

申请日：2013-07-12

Applicant: R.J. Reynolds Tobacco Company

Inventor： Jerry Wayne Marshall ,  Susan Marlene Adams ,  Darlene Madeline Lawson ,  Michael Francis Dube

IPC: A24B15/42

CPC classification number: A24B15/42 ,  A24B15/28 ,  A24B15/30 ,  A24B15/302

Abstract: A method of curing tobacco. The method comprises the steps of contacting a tobacco material with a curing additive comprising one or more salts and curing the tobacco material under conditions and temperature for a time sufficient to produce cured tobacco wherein the amount of the one or more salts contacted with the tobacco is at least 5 percent of the dry weight of the cured tobacco.

Abstract translation: 一种治疗烟草的方法。 该方法包括以下步骤：使烟草材料与包含一种或多种盐的固化添加剂接触，并在条件和温度下固化烟草材料足以产生固化烟草的时间，其中与烟草接触的一种或多种盐的量为 至少5％的干燥烟草干重。

公开(公告)号：US09010339B2

公开(公告)日：2015-04-21

申请号：US13117655

申请日：2011-05-27

Applicant: Michael Francis Dube ,  William Coleman

Inventor： Michael Francis Dube ,  William Coleman

IPC: C07C67/08 ,  C07C69/34 ,  A24B15/18 ,  A24B15/20 ,  A24B15/24 ,  A24B15/28 ,  C07C29/09 ,  A24B15/30 ,  C07C51/09

CPC classification number: A24B15/12 ,  A24B15/10 ,  A24B15/24 ,  A24B15/30 ,  A24B15/302 ,  C07C29/095 ,  C07C51/09 ,  C07C67/08 ,  C07C69/34 ,  C07C31/225 ,  C07C69/18 ,  C07C53/08

Abstract: A method for producing triacetin from one or more plants of genus Nicotiana is provided. The triacetin can be derived inter alia from Nicotiana species biomass or from seed. In certain embodiments, the triacetin is produced by condensation of glycerin, generated by hydrolysis of acylglycerol-containing starting material derived from tobacco biomass or seed, and acetic acid, also derived from tobacco biomass or seed. The invention also provides articles and compositions including tobacco articles and tobacco compositions that include triacetin produced from one or more plants of genus Nicotiana.

Abstract translation: 提供了从一种或多种烟草属植物生产三醋精的方法。 三醋精可以从烟草属物种生物量或种子中获得。 在某些实施方案中，通过由衍生自烟草生物质或种子的含酰基甘油的原料水解产生的甘油与来自烟草生物质或种子的乙酸的缩合产生三醋精。 本发明还提供了包括烟草制品和烟草组合物的制品和组合物，其包括由一种或多种烟草属植物产生的三醋精。