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公开(公告)号：US3282983A
公开(公告)日：1966-11-01
申请号：US46684665
申请日：1965-06-24
Applicant: TEXACO INC
Inventor： LACHOWICZ DONALD R , KREUZ KENNETH L
IPC: C07C201/12 , C07C205/40 , C07C409/40 , C10L1/23
CPC classification number: C10L1/231 , C07C201/10 , C07C201/12 , C07C407/00 , C07C205/40 , C07C409/40
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公开(公告)号：US3087972A
公开(公告)日：1963-04-30
申请号：US6081460
申请日：1960-10-06
Applicant: ROHM & HAAS
Inventor： EMMONS WILLIAM D , WHITE ROBERT W
IPC: C07C201/10 , C07C205/06 , C07C205/12 , C07C205/57
CPC classification number: C07C201/10 , C07C205/06 , C07C205/12 , C07C205/57
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公开(公告)号：US2275173A
公开(公告)日：1942-03-03
申请号：US36761140
申请日：1940-11-28
Applicant: REMINGTON ARMS CO INC
Inventor： WILLI BRUN
IPC: C07C205/24
CPC classification number: C07C201/10 , C07B2200/13 , Y10S149/111 , C07C205/24
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公开(公告)号：US2275171A
公开(公告)日：1942-03-03
申请号：US36760940
申请日：1940-11-28
Applicant: REMINGTON ARMS CO INC
Inventor： WILLI BRUN
IPC: C07C205/24
CPC classification number: C07C201/10 , C07B2200/13 , C07C205/24
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公开(公告)号：US2137234A
公开(公告)日：1938-11-22
申请号：US67404933
申请日：1933-06-02
Applicant: REMINGTON ARMS CO INC
Inventor： WILLI BRUN
IPC: C07C205/24
CPC classification number: C07C201/10 , C07B2200/13 , C07C205/24
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Patent Agency Ranking
公开(公告)号：US20140371446A1
公开(公告)日：2014-12-18
申请号：US14467625
申请日：2014-08-25
Applicant: AbbVie Inc.
Inventor： Shashank Shekhar , Thaddeus S. Franczyk , David M. Barnes , Travis B. Dunn , Anthony R. Haight , Vincent S. Chan
IPC: C07F9/6571 , C07F9/6584 , C07C41/09 , C07C315/04 , C07C273/18 , C07C1/30 , C07D209/34 , C07F5/02 , C07C15/14 , C07D295/033 , C07C319/18 , C07F9/40 , C07F9/6568 , C07C201/10
CPC classification number: C07F9/657163 , B01J31/189 , B01J31/2423 , B01J31/2466 , B01J31/2485 , B01J31/249 , B01J2231/344 , B01J2231/4227 , B01J2231/4283 , B01J2231/4288 , B01J2231/4294 , B01J2531/0205 , B01J2531/0266 , B01J2531/0288 , B01J2531/824 , B01J2540/10 , B01J2540/40 , C07C1/30 , C07C1/321 , C07C15/14 , C07C17/093 , C07C17/361 , C07C41/09 , C07C45/68 , C07C201/10 , C07C253/30 , C07C273/1854 , C07C273/1863 , C07C303/40 , C07C315/04 , C07C319/14 , C07C319/18 , C07C2523/42 , C07C2523/44 , C07C2523/46 , C07C2523/52 , C07C2523/72 , C07C2523/75 , C07C2523/755 , C07C2527/14 , C07C2531/22 , C07C2531/24 , C07D209/34 , C07D239/54 , C07D295/033 , C07F5/027 , C07F9/40 , C07F9/65031 , C07F9/65515 , C07F9/6552 , C07F9/65683 , C07F9/6571 , C07F9/6584 , Y02P20/52 , C07C275/28 , C07C311/08 , C07C311/21 , C07C311/29 , C07C255/10 , C07C321/30 , C07C205/45 , C07C15/06 , C07C49/784 , C07C25/18
Abstract: The disclosure is directed to: (a) phosphacycle ligands; (b) methods of using such phosphacycle ligands in bond forming reactions; and (c) methods of preparing phosphacycle ligands.
Abstract translation: 本公开涉及：（a）磷酸基配体; （b）在成键反应中使用这种磷酸基配体的方法; 和（c）制备磷酸基配体的方法。
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37.发明申请NOVEL PROCESS FOR PREPARING PHENYLCYCLOPROPYLAMINE DERIVATIVES USING NOVEL INTERMEDIATES 审中-公开使用新型中间体制备苯甲酰胺衍生物的新方法公开(公告)号：US20140323727A1
公开(公告)日：2014-10-30
申请号：US14320853
申请日：2014-07-01
Applicant: ACTAVIS GROUP PTC EHF
Inventor： Anil Shahaji Khile , Jayesh Patel , Nikhil Trivedi , Nitin Sharadchandra Pradhan
IPC: C07C209/34 , C07C205/26 , C07C205/05 , C07C205/45
CPC classification number: C07C209/34 , C07C45/46 , C07C201/10 , C07C201/12 , C07C205/05 , C07C205/10 , C07C205/16 , C07C205/26 , C07C205/45 , C07C211/40 , C07C2601/02 , C07C49/233
Abstract: Provided herein is a novel process for the preparation of phenylcyclopropylamine derivatives, which are useful intermediates in the preparation of triazolo[4,5-d]pyrimidine compounds. Provided particularly herein is a novel, commercially viable and industrially advantageous process for the preparation of a substantially pure ticagrelor intermediate, trans-(1R,2S)-2-(3,4-difluorophenyl)-cyclopropylamine. The intermediate is useful for preparing ticagrelor, or a pharmaceutically acceptable salt thereof, in high yield and purity.
Abstract translation: 本文提供了一种制备苯基环丙基胺衍生物的新方法，其是三唑并[4,5-d]嘧啶化合物的制备中的有用中间体。 本文特别提供了一种用于制备基本上纯粹的泰格列洛中间体反式 - （1R，2S）-2-（3,4-二氟苯基） - 环丙胺的新颖的，商业上可行的和工业上有利的方法。 中间体可用于以高产率和纯度制备替卡格雷或其药学上可接受的盐。
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公开(公告)号：US20140235895A1
公开(公告)日：2014-08-21
申请号：US14114305
申请日：2012-04-27
Applicant: Srinivas Katkam , Rajeswar Reddy Sagyam , Raghavendar Rao Morthala , Babu Ireni , Krishna Vinigari , Suresh Kumar Ramdoss , Srinivasulu Rangineni , Arjunkumar Tummala , Javed Iqbal , Srinivas Oruganti , Bhaskar Kandagatla
Inventor： Srinivas Katkam , Rajeswar Reddy Sagyam , Raghavendar Rao Morthala , Babu Ireni , Krishna Vinigari , Suresh Kumar Ramdoss , Srinivasulu Rangineni , Arjunkumar Tummala , Javed Iqbal , Srinivas Oruganti , Bhaskar Kandagatla
IPC: C07C205/45 , C07C213/10 , C07C215/28 , C07C213/00
CPC classification number: C07C205/45 , C07C201/10 , C07C201/12 , C07C213/00 , C07C213/02 , C07C213/10 , C07C215/28 , C07C205/04
Abstract: The present application provide processes for the preparation of fingolimod and its pharmaceutically acceptable salts, process for the purification of fingolimod hydrochloride and process for the preparation of amorphous fingolimod hydrochloride.
Abstract translation: 本申请提供了芬戈莫德及其药学上可接受的盐的制备方法，盐酸芬戈莫德的纯化方法和用于制备无定形芬戈莫德盐酸盐的方法。
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公开(公告)号：US08546619B2
公开(公告)日：2013-10-01
申请号：US12735886
申请日：2009-02-26
Applicant: Jacob Oren
Inventor： Jacob Oren
IPC: C07C201/12 , C07C205/08
CPC classification number: C07C201/10 , C07C201/12 , C07C205/15
Abstract: The invention provides a process for preparing bronopol, which process comprises charging a reaction vessel with water, bromopicrin, nitromethane and paraformaldehyde, gradually feeding a base into said reaction vessel under stirring, bringing the reaction to completion and separating bronopol from the aqueous reaction mixture.
Abstract translation: 本发明提供了一种制备青霉酚的方法，该方法包括向反应容器中加入水，溴氰菊酯，硝基甲烷和多聚甲醛，在搅拌下逐渐向碱性物质中加入碱，使反应完成，并从反应混合物中分离出丙三醇。
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公开(公告)号：US20130217876A1
公开(公告)日：2013-08-22
申请号：US13591117
申请日：2012-08-21
Applicant: Shashank Shekhar , Thaddeus S. Franczyk , David M. Barnes , Travis B. Dunn , Anthony R. Haight , Vincent S. Chan
Inventor： Shashank Shekhar , Thaddeus S. Franczyk , David M. Barnes , Travis B. Dunn , Anthony R. Haight , Vincent S. Chan
IPC: B01J31/24 , C07D209/12 , C07D213/76 , C07D265/30 , C07C253/30 , C07C201/10 , C07D209/34 , C07C303/40 , C07D239/54
CPC classification number: B01J31/2423 , B01J31/189 , B01J31/2419 , B01J31/2438 , B01J31/2466 , B01J31/2485 , B01J31/249 , B01J2231/4211 , B01J2231/4227 , B01J2231/4277 , B01J2231/4283 , B01J2231/4288 , B01J2231/4294 , B01J2231/44 , B01J2531/0205 , B01J2531/0266 , B01J2531/0288 , B01J2531/824 , B01J2540/10 , B01J2540/40 , C07C1/26 , C07C1/30 , C07C1/321 , C07C17/093 , C07C17/2635 , C07C17/361 , C07C41/01 , C07C41/30 , C07C45/61 , C07C45/68 , C07C45/71 , C07C201/10 , C07C253/14 , C07C253/30 , C07C273/1854 , C07C273/1863 , C07C303/36 , C07C303/40 , C07C319/14 , C07C2531/24 , C07C2531/26 , C07D209/12 , C07D209/34 , C07D209/42 , C07D213/76 , C07D239/54 , C07D265/30 , C07D295/033 , C07F1/02 , C07F5/025 , C07F5/04 , C07F9/4021 , C07F9/4841 , C07F9/505 , C07F9/5072 , C07F9/509 , C07F9/572 , C07F9/65031 , C07F9/65583 , C07F9/65683 , C07F9/657163 , Y02P20/52 , C07C275/28 , C07C311/08 , C07C311/21 , C07C311/29 , C07C255/10 , C07C321/30 , C07C205/45 , C07C15/06 , C07C49/784
Abstract: The disclosure is directed to: (a) phosphacycle ligands; (b) catalyst compositions comprising phosphacycle ligands; and (c) methods of using such phosphacycle ligands and catalyst compositions in bond forming reactions.
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