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183 条记录 (耗时 0.019 秒)

    Pyridinyl cyclohexanecarboxamide cooling compounds
    41.
    发明授权
    Pyridinyl cyclohexanecarboxamide cooling compounds 有权

    公开(公告)号：US10221136B2

    公开(公告)日：2019-03-05

    申请号：US15276248

    申请日：2016-09-26

    申请人： Givaudan, S.A.

    发明人： Karen Ann Bell ,  Christophe C. Galopin ,  Jay Patrick Slack ,  Lori W. Tigani

    IPC分类号： C07D213/40 ,  A61Q11/00 ,  A23L2/56 ,  A61K8/49

    摘要： A method of providing a cooling effect to a product includes the incorporation into the product of at least one compound of the formula I in which m is a number between 0 and 2, X, Y and Z are selected independently from the group consisting of H, halogen, OH, Me, Et, MeO and EtO, and R1, R2 and R3 together comprise at least 6 carbons, selected such that (a) (i) R1 is selected from the group consisting of H, Me, Et, isopropyl and C4-C5 branched alkyl; and  (ii) R2 and R3 are independently selected from the group consisting of Me, Et, isopropyl and Ca-branched alkyl; or (b) any two or all of R1, R2 and R3 together form a monocyclic, bicyclic or tricyclic radical having up to 10 carbons. The compounds confer substantial cooling effects on compositions applied to the skin or taken orally, such as toothpastes, mouthwashes, foodstuffs, beverages, confectionery, tobacco products, skin creams and ointments.

    Process For Preparing Spirogalbanone
    42.
    发明申请
    Process For Preparing Spirogalbanone 审中-公开

    公开(公告)号：US20190055181A1

    公开(公告)日：2019-02-21

    申请号：US16070687

    申请日：2017-02-13

    申请人： Givaudan, S.A.

    发明人： Simon ELLWOOD ,  William Alexander THIAM

    IPC分类号： C07C45/51 ,  C07C41/01 ,  C07C41/30 ,  C07C41/18 ,  C07C49/557

    摘要： A method of making spirogalbanone includes the steps of: (a) subjecting ethynylspirodecanol to a Rupe rearrangement to give a compound of the formula I (b) converting the compound of (a) to a C1-C4 alkyl acetal; (c) subjecting the acetal to a trans-acetalisation reaction with allyl alcohol in the presence of a mild acid catalyst; (d) heating the product of (c) in the presence of an acid catalyst to give an allylenolether; and (e) subjecting the product of (d) to a Claisen rearrangement to give spirogalbanone. The method affords an easier and more efficient method of preparation.

    PROCESS FOR THE CYCLOPROPANATION OF OLEFINS USING N-METHYL-N-NITROSO COMPOUNDS
    43.
    发明申请
    PROCESS FOR THE CYCLOPROPANATION OF OLEFINS USING N-METHYL-N-NITROSO COMPOUNDS 审中-公开

    公开(公告)号：US20190055172A1

    公开(公告)日：2019-02-21

    申请号：US15758795

    申请日：2016-09-14

    申请人： Givaudan, S.A.

    发明人： Fridtjof SCHRÖDER ,  Marcel STECK

    IPC分类号： C07C2/86

    摘要： A process of converting a carbon-carbon double bond on a substrate into a cyclopropane ring, which method comprises the step of treating the substrate with a N-alkyl-N-nitroso compound, a transition metal catalyst and an aqueous base, wherein the N-alkyl-N-nitroso compound is formed by reacting an alkyl amine with an alkali metal nitrite in the presence of a mono-basic or di-basic acid, or a mixture thereof, and wherein the N-alkyl-N-nitroso compound is not distilled before it is mixed with the substrate, catalyst and base.

    PERFUME COMPOSITIONS
    46.
    发明申请
    PERFUME COMPOSITIONS 有权

    公开(公告)号：US20170260476A1

    公开(公告)日：2017-09-14

    申请号：US15457537

    申请日：2017-03-13

    申请人： Givaudan S.A.

    发明人： Philippe Blondeau ,  Alice Bresson Boil

    IPC分类号： C11B9/00

    CPC分类号： C11B9/0019 ,  A01N25/18 ,  A01N27/00 ,  A01N49/00 ,  A61L9/013 ,  A61L2209/13 ,  C11B9/0003 ,  C11B9/0015

    摘要： A perfume composition having controlled release of phytoncides in an atmosphere in order to generate an air condition resembling the air environment of a forest is provided. The perfume composition includes a) at least about 0.6% by weight of at least one phytoncide; and b) a perfume mixture including (i) at least one solvent; and (ii) at least one fragrance ingredient. At least about 25% by weight of the at least one phytoncide is selected from the group consisting of pinene alpha, pinene beta and combinations thereof.