公开(公告)号：US09370312B2

公开(公告)日：2016-06-21

申请号：US11845973

申请日：2007-08-28

Applicant: Yitzhack Schwartz ,  Meir Bar-Tal ,  Joshua Porath

Inventor： Yitzhack Schwartz ,  Meir Bar-Tal ,  Joshua Porath

IPC: A61B5/042 ,  A61B5/0408 ,  A61B5/053 ,  A61B5/00 ,  A61B18/00

CPC classification number: A61B5/0422 ,  A61B5/04085 ,  A61B5/0538 ,  A61B5/6805 ,  A61B2018/00839

Abstract: A reliable endocardial map is obtained by constructing a matrix relationship between a small number of endocardial points and a large number of external receiving points using a multi-electrode chest panel. Inversion of the matrix yields information allowing the endocardial map to be constructed. Subsequent maps are obtained noninvasively using the multi-electrode chest panel, applying new electrical signals to the matrix relationship, and again inverting the matrix to generate new endocardial electrical maps.

Abstract translation: 通过使用多电极胸板在少量心内膜点和大量外部接收点之间构建矩阵关系来获得可靠的心内膜图。 矩阵的反演产生允许构建心内膜图的信息。 使用多电极胸板非侵入性地获得随后的图，将新的电信号应用于矩阵关系，并且再次反转矩阵以产生新的心内膜电图。

公开(公告)号：US09101333B2

公开(公告)日：2015-08-11

申请号：US13295594

申请日：2011-11-14

Applicant: Yitzhack Schwartz

Inventor： Yitzhack Schwartz

IPC: A61B18/00 ,  A61B5/00 ,  A61N7/02 ,  A61B18/14 ,  A61B18/24 ,  A61B19/00 ,  A61B5/0452

CPC classification number: A61B5/7285 ,  A61B5/0452 ,  A61B5/046 ,  A61B18/1492 ,  A61B18/24 ,  A61B34/20 ,  A61B34/25 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2034/252 ,  A61B2090/065 ,  A61B2090/364 ,  A61N7/022

Abstract: Cardiac tissue ablation is carried out by defining first regions containing first locations including ganglionated plexi in a heart of a living subject, and inserting a probe into the heart. The method is further carried out by detecting electrical activity in the heart via electrodes on the distal portion of the probe, defining second regions having second locations, wherein the electrical activity exhibits a dominant frequency that is higher than a predefined threshold, defining third regions having third locations, wherein the electrical activity exhibits complex fractionated atrial electrograms, constructing an electroanatomical map of the heart that defines intersections of the first regions and at least one of the second regions and the third regions, selecting ablation sites within the intersections, and ablating cardiac tissue at the ablation sites.

Abstract translation: 通过在生物体的心脏中限定含有神经节丛的第一位置的第一区域，并将探针插入心脏来进行心脏组织消融。 通过在探针的远端部分上的电极检测心脏中的电活动来限定该方法，限定具有第二位置的第二区域，其中电活动表现出高于预定义阈值的主频率，限定第三区域具有 第三位置，其中所述电活动显示复杂的分级心房电图，构建定义所述第一区域和所述第二区域和所述第三区域中的至少一个的交叉点的心脏的电解剖图，选择所述交叉点内的消融位点，以及消融心脏 消融部位的组织。

公开(公告)号：US07996059B2

公开(公告)日：2011-08-09

申请号：US11370666

申请日：2006-03-08

Applicant: Joshua Porath ,  Yitzhack Schwartz

Inventor： Joshua Porath ,  Yitzhack Schwartz

IPC: A61B5/05 ,  A61B18/04 ,  A61H1/00

CPC classification number: A61B5/06 ,  A61B5/061 ,  A61B5/4233 ,  A61B5/6885 ,  A61B6/12 ,  A61B8/0833 ,  A61B2562/164

Abstract: A device for enhancing visualization of an esophagus when imaged by a visualization system includes a structure including material that is clearly visible when imaged by the visualization system. The structure is arranged, when inserted into the esophagus, to expand so as to conform to an inner surface of the esophagus in order to enhance a visualization quality of the surface when imaged by the visualization system. A cord attached to the structure is arranged to extend out of the esophagus so as to assist a removal of the device from the esophagus.

Abstract translation: 用于增强由可视化系统成像时食管可视化的装置包括包括当由可视化系统成像时清晰可见的材料的结构。 当插入到食道中时，该结构被布置成扩展以便与食管的内表面一致，以便在由可视化系统成像时增强表面的可视化质量。 安装在该结构上的绳索被布置成延伸出食道以协助从食道中移除该装置。

公开(公告)号：US20100069763A1

公开(公告)日：2010-03-18

申请号：US12211592

申请日：2008-09-16

Applicant: Assaf Govari ,  Yaron Ephrath ,  Yitzhack Schwartz

Inventor： Assaf Govari ,  Yaron Ephrath ,  Yitzhack Schwartz

IPC: A61B5/0215

CPC classification number: A61B5/0215 ,  A61B5/6846

Abstract: Pressure-sensing apparatus includes a sensor die, which is configured for percutaneous insertion through a wall of a blood vessel of a patient so as to generate an electrical signal that is responsive to a pressure in the blood vessel. A wire has a first end connected to the sensor die and a second end connected to an electronics package, which is configured for subcutaneous implantation and is connected via the wire to receive and process the electrical signal that is generated by the sensor die in order to provide an output that is indicative of the pressure.

Abstract translation: 压力感测装置包括传感器管芯，其被配置为经皮穿过患者的血管的壁，以产生响应于血管中的压力的​​电信号。 线具有连接到传感器管芯的第一端和连接到电子封装的第二端，电子封装构造成用于皮下植入，并且经由导线连接以接收和处理由传感器裸片产生的电信号，以便 提供一个表示压力的输出。

公开(公告)号：US20100069707A1

公开(公告)日：2010-03-18

申请号：US12624775

申请日：2009-11-24

Applicant: Assaf Govari ,  Andres Altmann ,  Yaron Ephrath ,  Yitzhack Schwartz

Inventor： Assaf Govari ,  Andres Altmann ,  Yaron Ephrath ,  Yitzhack Schwartz

IPC: A61F2/00

CPC classification number: A61F5/0059 ,  A61F5/0056

Abstract: The problem of accessing an injection port transcutaneously is resolved using wireless position transducers in an inflation port assembly and in an injection syringe. The measurements provided by the transducers indicate to the practitioner the position and orientation of syringe relative to the injection port. A console provides a visual indication of the relative position and orientation so as to guide the practitioner to insert the syringe at the proper site and in the proper direction and to penetrate the port cleanly and correctly.

Abstract translation: 通过充气端口组件和注射器中的无线位置传感器来解决通过经皮接入注射口的问题。 由换能器提供的测量指示从业者注射器相对于注射口的位置和取向。 控制台提供相对位置和方向的可视指示，以便引导从业者将注射器插入正确的位置并且沿正确的方向并且清洁地且正确地穿透端口。

公开(公告)号：US20100057157A1

公开(公告)日：2010-03-04

申请号：US12200297

申请日：2008-08-28

Applicant: Assaf Govari ,  Yitzhack Schwartz

Inventor： Assaf Govari ,  Yitzhack Schwartz

IPC: A61N1/365

CPC classification number: A61N1/36514 ,  A61B5/0031 ,  A61B5/061 ,  A61B2034/2051 ,  A61N1/056 ,  A61N1/36521 ,  A61N1/36535 ,  A61N1/36578

Abstract: A pacemaker with position sensing capability permits built-in monitoring of hemodynamic changes. A miniature position sensor, such as a magnetic coil, is fixed to each implanted pacing lead. The pacemaker housing contains a generator unit, including a magnetic field transmitter. The magnetic field transmitted by the generator unit causes the position sensors to generate position signals, which are returned via the pacing leads to a control unit of the pacemaker. Based on these signals, the control unit senses relative positions of the location sensors, and hence the motion of the leads in the heart. Other location sensing techniques are also disclosed.

Abstract translation: 具有位置检测功能的起搏器允许内部监测血液动力学变化。 诸如电磁线圈的微型位置传感器固定到每个植入的起搏引线上。 起搏器外壳包含发电机单元，包括磁场发射器。 由发生器单元传输的磁场使得位置传感器产生位置信号，该位置信号通过起搏器返回到起搏器的控制单元。 基于这些信号，控制单元感测位置传感器的相对位置，并且因此感测心脏中引线的运动。 还公开了其他位置感测技术。

公开(公告)号：US07558616B2

公开(公告)日：2009-07-07

申请号：US10173197

申请日：2002-06-17

Applicant: Assaf Govari ,  Yitzhack Schwartz

Inventor： Assaf Govari ,  Yitzhack Schwartz

IPC: A61B5/05

CPC classification number: A61B5/06 ,  A61B5/061 ,  A61B5/062 ,  A61B10/0041 ,  A61B10/0233 ,  A61B17/1114 ,  A61B17/3403 ,  A61B34/20 ,  A61B34/25 ,  A61B90/36 ,  A61B90/39 ,  A61B2010/045 ,  A61B2017/008 ,  A61B2017/3413 ,  A61B2034/107 ,  A61B2034/2051 ,  A61B2034/2063 ,  A61B2034/2072 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3929 ,  A61B2090/3954 ,  A61B2090/3958 ,  A61B2090/397

Abstract: Apparatus for locating a tissue within a body of a subject includes an acoustic tag configured to be fixed to the tissue and adapted, responsive to acoustic waves incident thereon, to return acoustic echoes. Acoustic transducers are placed at respective positions so as to direct the acoustic waves into the body toward the tissue and to receive the acoustic echoes returned from the tag responsive to the acoustic waves, generating first signals responsive to the received echoes. Transducer position sensors are coupled respectively to the acoustic transducers so as to generate second signals indicative of the respective positions of the acoustic transducers in an external frame of reference. A processing unit processes the first signals and the second signals so as to determine coordinates of the acoustic tag in the external frame of reference.

Abstract translation: 用于定位对象的身体内的组织的装置包括被配置为固定到组织并响应于入射在其上的声波而适应以返回声学回声的声学标签。 声学换能器被放置在相应的位置，以便将声波引向身体朝向组织，并且响应于声波接收从标签返回的声学回波，产生响应于所接收的回波的第一信号。 传感器位置传感器分别耦合到声换能器，以便产生指示声换能器在外部参照系中各自位置的第二信号。 处理单元处理第一信号和第二信号，以便确定外部参照系中的声标签的坐标。

公开(公告)号：US20080287776A1

公开(公告)日：2008-11-20

申请号：US11749387

申请日：2007-05-16

Applicant: Yaron Ephrath ,  Assaf Govari ,  Andres Altmann ,  Yitzhack Schwartz

Inventor： Yaron Ephrath ,  Assaf Govari ,  Andres Altmann ,  Yitzhack Schwartz

IPC: A61B17/12

CPC classification number: A61F5/0059 ,  A61F5/0056

Abstract: The problem of accessing an injection port transcutaneously is resolved using wireless position transducers in an inflation port assembly and in an injection syringe. The measurements provided by the transducers indicate to the practitioner the position and orientation of syringe relative to the injection port. A console provides a visual indication of the relative position and orientation so as to guide the practitioner to insert the syringe at the proper site and in the proper direction and to penetrate the port cleanly and correctly.

Abstract translation: 通过充气端口组件和注射器中的无线位置传感器来解决访问注射口的问题。 由换能器提供的测量指示从业者注射器相对于注射口的位置和取向。 控制台提供相对位置和方向的可视指示，以便引导从业者将注射器插入正确的位置并且沿正确的方向并且清洁地且正确地穿透端口。

公开(公告)号：US20080140073A1

公开(公告)日：2008-06-12

申请号：US12032278

申请日：2008-02-15

Applicant: Yitzhack Schwartz

Inventor： Yitzhack Schwartz

IPC: A61B18/14 ,  A61B17/34

CPC classification number: A61B5/06 ,  A61B1/3137 ,  A61B5/0422 ,  A61B5/064 ,  A61B6/503 ,  A61B6/504 ,  A61B8/0883 ,  A61B8/0891 ,  A61B18/1492 ,  A61B34/20 ,  A61B2017/00053 ,  A61B2017/00243 ,  A61B2017/00292 ,  A61B2018/00351 ,  A61B2018/00839 ,  A61B2018/1467 ,  A61B2034/2051

Abstract: A method for performing a procedure at the fossa ovalis in the septal wall of the heart includes the steps of providing a sheath having a body wherein the body has a lumen extending therethrough and an open end at a distal end of the body. The body also has at least one electrode at the distal end of the body. The fossa ovalis in the septal wall is identified by using the at least one electrode of the sheath.

Abstract translation: 用于在心脏隔膜中的卵圆窝进行手术的方法包括提供具有身体的护套的步骤，其中主体具有延伸穿过其中的内腔和身体远端的开口端。 身体还在身体的远端具有至少一个电极。 通过使用护套的至少一个电极来识别隔膜中的卵圆窝。

公开(公告)号：US20070049817A1

公开(公告)日：2007-03-01

申请号：US11215435

申请日：2005-08-30

Applicant: Assaf Preiss ,  Yitzhack Schwartz

Inventor： Assaf Preiss ,  Yitzhack Schwartz

IPC: A61B5/05

CPC classification number: A61B5/0422 ,  A61B5/0538 ,  A61B5/06 ,  A61B5/062 ,  A61B5/063 ,  A61B6/12 ,  A61B6/5247 ,  A61B6/541 ,  A61B8/12 ,  A61B8/4488 ,  A61B8/5238 ,  A61B8/543 ,  G06K9/00 ,  G06K2209/05 ,  G06T5/50 ,  G06T7/30 ,  G06T2207/10132 ,  G06T2207/30048

Abstract: Systems and methods are provided for registering maps with images, involving segmentation of three-dimensional images and registration of images with an electro-anatomical map using physiological or functional information in the maps and the images, rather than using only location information. A typical application of the invention involves registration of an electro-anatomical map of the heart with a preacquired or real-time three-dimensional image. Features such as scar tissue in the heart, which typically exhibits lower voltage than healthy tissue in the electro-anatomical map, can be localized and accurately delineated on the three-dimensional image and map.

Abstract translation: 提供了系统和方法，用于使用图像登记地图，涉及使用地图和图像中的生理或功能信息的三维图像的分割和使用电解剖图进行的图像配准，而不是仅使用位置信息。 本发明的典型应用包括将心脏的电解剖图谱与预先获取的或实时的三维图像进行配准。 在电解剖图中通常表现出比健康组织更低电压的心脏中的瘢痕组织的特征可以在三维图像和图上被局部化并准确地描绘。