公开(公告)号：US06277885B1

公开(公告)日：2001-08-21

申请号：US09491636

申请日：2000-01-27

申请人： Jeremy I. Levin ,  James M. Chen

发明人： Jeremy I. Levin ,  James M. Chen

IPC分类号： A61K31185

CPC分类号： C07D405/12 ,  A61K31/5375 ,  A61K31/54 ,  C07C311/29 ,  C07C2601/04 ,  C07D213/68 ,  C07D309/12 ,  C07F9/36

摘要： Hydroxamic acids having the formula are useful in treating disease conditions mediated by TNF-&agr;, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.

摘要翻译： 具有该化学式的羟肟酸可用于治疗由TNF-α介导的疾病状态，例如类风湿性关节炎，骨关节炎，败血症，AIDS，溃疡性结肠炎，多发性硬化，克罗恩病和退行性软骨损失。

公开(公告)号：US06225311B1

公开(公告)日：2001-05-01

申请号：US09492691

申请日：2000-01-27

申请人： Jeremy I. Levin ,  James M. Chen ,  Derek C. Cole ,  Mila T. Du ,  Leif M. Laakso

发明人： Jeremy I. Levin ,  James M. Chen ,  Derek C. Cole ,  Mila T. Du ,  Leif M. Laakso

IPC分类号： A61K3154

CPC分类号： C07C311/29 ,  A61K31/5375 ,  A61K31/54 ,  C07C2601/04 ,  C07D213/68 ,  C07D279/10 ,  C07D279/12 ,  C07D309/12 ,  C07F9/36

摘要： Compounds of the formula: are useful in treating disease conditions mediated by TNF-&agr;, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.

摘要翻译： 下式的化合物可用于治疗由TNF-α介导的疾病状况，例如类风湿性关节炎，骨关节炎，败血症，AIDS，溃疡性结肠炎，多发性硬化，克罗恩病和退行性软骨损失。

公开(公告)号：US6042795A

公开(公告)日：2000-03-28

申请号：US528903

申请日：1995-09-15

申请人： James M. Chen ,  Pascaline H. Nguyen ,  Ralph E. Truitt

发明人： James M. Chen ,  Pascaline H. Nguyen ,  Ralph E. Truitt

IPC分类号： B01D53/14 ,  B01D53/86 ,  F23G7/06 ,  F23G7/07 ,  B01D53/38

CPC分类号： F23G7/07 ,  B01D53/1487 ,  B01D53/8668 ,  F23J2217/102 ,  F23J2217/50

摘要： Methods and apparatus for the catalytic oxidation treatment of waste gas streams that contain entrained solids and gaseous air pollutants such as volatile organic compounds and carbon monoxide, and particularly methods and apparatus suitable for treating waste gas streams from wood burning processes. The method includes a step of washing the gas stream with water prior to the 5catalytic oxidation treatment.

摘要翻译： 用于催化氧化处理含有夹带的固体和气态空气污染物如挥发性有机化合物和一氧化碳的废气流的方法和装置，以及特别是适用于处理来自木材燃烧过程的废气流的方法和装置。 该方法包括在催化氧化处理之前用水洗涤气流的步骤。

公开(公告)号：US5871347A

公开(公告)日：1999-02-16

申请号：US831108

申请日：1997-04-01

申请人： James M. Chen ,  Pascaline H. Nguyen ,  James C. Fu

发明人： James M. Chen ,  Pascaline H. Nguyen ,  James C. Fu

IPC分类号： B01D53/86 ,  B01D53/88 ,  B01J19/24 ,  B01J19/28 ,  B01J35/04 ,  F23G7/06 ,  F23G7/07 ,  F01N3/10

CPC分类号： F23G7/07 ,  B01D53/864 ,  B01D53/8668 ,  B01D53/885 ,  B01J19/24 ,  B01J19/2485 ,  B01J19/28 ,  B01J35/04 ,  F23G7/068 ,  B01J2208/00716 ,  B01J2219/00135 ,  B01J2219/00157 ,  B01J2219/00243 ,  Y02E20/12

摘要： A system for the abatement of industrial process gases utilizes a rotary regenerative oxidizer comprised of one or more heat exchange beds, each bed comprised of a parallel, axial, and longitudinal array of heat regenerative channels that thermally and/or catalytically oxidize contaminated gases. Utilizing a rotary regenerative oxidizer, and if desired, a plurality of heat regenerative beds incorporated therein, facilitates the use of regenerative technology at lower gas flow rates, increases thermal efficiency, and significantly reduces the floor space normally required when implementing fixed-bed nonrotary regenerative oxidizers. The heat exchange channels may be catalytically treated to enhance oxidation of the pollutants at a lower temperature.

公开(公告)号：US5024981A

公开(公告)日：1991-06-18

申请号：US340992

申请日：1989-04-20

申请人： Barry K. Speronello ,  John W. Byrne ,  James M. Chen

发明人： Barry K. Speronello ,  John W. Byrne ,  James M. Chen

IPC分类号： B01D53/94 ,  B01J29/06 ,  B01J29/072 ,  B01J29/80

CPC分类号： B01J35/0006 ,  B01D53/9418 ,  B01J29/072 ,  B01J29/24 ,  B01J29/7615 ,  B01J37/0246 ,  B01D2251/2062 ,  B01D2255/20738 ,  B01D2255/20761 ,  B01D2255/50 ,  Y02C20/10

摘要： A zeolite catalyst composition is provided in which a first or upstream zone of the catalyst has a lower metal (e.g., iron or copper) promoter loading than the metal promoter loading of the second or downstream zone of the catalyst. The first zone may contain from none up to about 1 percent by weight of the promoter and the second zone may contain from about 1 to 30 percent by weight promoter. The zeolite may be any suitable zeolite, especially one having a silica-to-alumina ratio of about 10 or more, and a kinetic pore size of about 7 to about 8 Angstroms with such pores being interconnected in all three crystallographic dimensions. The method of the invention provides for passing a gaseous stream containing oxygen, nitrogen oxides and ammonia sequentially through first and second catalysts as described above, the first catalyst favoring reduction of nitrogen oxides and the second catalyst favoring the oxidation or other decomposition of excess ammonia.

公开(公告)号：US4767521A

公开(公告)日：1988-08-30

申请号：US943175

申请日：1986-12-18

申请人： Robert J. Feldman ,  James M. Chen ,  Andrei Rhoe ,  Roger P. Van Driesen ,  C. Bertil Fogman ,  Donald P. Satchell

发明人： Robert J. Feldman ,  James M. Chen ,  Andrei Rhoe ,  Roger P. Van Driesen ,  C. Bertil Fogman ,  Donald P. Satchell

IPC分类号： C10G9/00 ,  C10G55/04 ,  C10G67/02 ,  C10G67/04

CPC分类号： C10G9/007 ,  C10G55/04 ,  C10G67/02 ,  C10G67/049

摘要： Prior to upgrading a viscous feed by visbreaking, at least a portion of the feed is treated to remove a heavy phase in specified amounts, whereby the severity of the visbreaking may be increased. The Shell Hot Filtration number of the visbreaking product is reduced by at least 75%, compared to visbreaking of untreated feed at some severity.

公开(公告)号：US4596650A

公开(公告)日：1986-06-24

申请号：US590175

申请日：1984-03-16

申请人： Harvey D. Schindler ,  James M. Chen

发明人： Harvey D. Schindler ,  James M. Chen

IPC分类号： C10G1/06 ,  C10G1/00

CPC分类号： C10G1/006

摘要： Sub-bituminous coal is directly liquefied in two stages by use of a liquefaction solvent containing insoluble material as well as 850.degree. F.+ material and 850.degree. F.- material derived from the second stage, and controlled temperature and conversion in the second stage. The process is in hydrogen balance.

摘要翻译： 次烟煤通过使用含有不溶性物质的液化溶剂以及衍生自第二阶段的850°F +材料和850°F的物质直接液化，在第二阶段中控制温度和转化率 。 该过程处于氢平衡。

公开(公告)号：US4314980A

公开(公告)日：1982-02-09

申请号：US125406

申请日：1980-02-28

申请人： Ming-Shing Shen ,  James M. Chen ,  Ralph T. Yang

发明人： Ming-Shing Shen ,  James M. Chen ,  Ralph T. Yang

IPC分类号： C01B33/24

CPC分类号： C01B33/24

摘要： This invention relates to the preparation of fine particles of reactive beta-dicalcium silicate by means of a solid state process which comprises firing a mixture of calcium sulfate, silica and a reducing additive selected from the group consisting of calcium sulfide, carbon, carbon monoxide, methane and hydrogen, at a temperature of about 850.degree.-1000.degree. C. A carrier gas such as nitrogen or carbon dioxide may also be added, if desired. A high concentration of sulfur dioxide is a by-product of this process.

摘要翻译： 本发明涉及通过固态方法制备反应性β-二硅酸二钙细颗粒，其包括硫酸钙，二氧化硅和还原添加剂的混合物的烧制，所述还原添加剂选自硫化钙，碳，一氧化碳， 甲烷和氢气，在约850℃-1000℃的温度下。如果需要，也可以加入载气如氮气或二氧化碳。 高浓度的二氧化硫是这个过程的副产品。

公开(公告)号：US07842672B2

公开(公告)日：2010-11-30

申请号：US11825395

申请日：2007-07-06

申请人： Constantine G. Boojamra ,  James M. Chen ,  Alan X. Huang ,  Choung U. Kim ,  Kuei-Ying Lin ,  Richard L. Mackman ,  David A. Oare ,  Jason K. Perry ,  Oliver L. Saunders ,  Sundaramoorthi Swaminathan ,  Lijun Zhang

发明人： Constantine G. Boojamra ,  James M. Chen ,  Alan X. Huang ,  Choung U. Kim ,  Kuei-Ying Lin ,  Richard L. Mackman ,  David A. Oare ,  Jason K. Perry ,  Oliver L. Saunders ,  Sundaramoorthi Swaminathan ,  Lijun Zhang

IPC分类号： A01N43/04 ,  A61K31/70

CPC分类号： C07H19/00

摘要： A compound of Formula I, Formula II, Formula III, or Formula IV: or a pharmaceutically acceptable salt, solvate, and/or ester thereof, therapeutic compositions containing such compounds, and therapeutic methods that include the administration of such compounds.

摘要翻译： 式I，式II，式III或式IV化合物或其药学上可接受的盐，溶剂化物和/或酯，含有这些化合物的治疗组合物，以及包括施用这些化合物的治疗方法。

公开(公告)号：US07741345B2

公开(公告)日：2010-06-22

申请号：US11880067

申请日：2007-07-19

申请人： Carina E. Cannizzaro ,  James M. Chen ,  Manoj C. Desai ,  Michael L. Mitchell ,  Sundaramoorthi Swaminathan ,  Lianhong Xu

发明人： Carina E. Cannizzaro ,  James M. Chen ,  Manoj C. Desai ,  Michael L. Mitchell ,  Sundaramoorthi Swaminathan ,  Lianhong Xu

IPC分类号： A61K31/4427 ,  A61K31/443 ,  C07D405/02

CPC分类号： C07D493/04 ,  C07D405/12 ,  C07D519/00

摘要： The invention is related to compounds of Formula I: or a pharmaceutically acceptable salt, solvate, ester, and/or phosphonate thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.

摘要翻译： 本发明涉及式I化合物或其药学上可接受的盐，溶剂合物，酯和/或膦酸盐，含有这些化合物的组合物，以及包括施用这些化合物的治疗方法。