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    Diagnostic cassette
    44.
    发明授权
    Diagnostic cassette 有权

    公开(公告)号：US11486839B2

    公开(公告)日：2022-11-01

    申请号：US15300698

    申请日：2014-04-25

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Nicholas Matthew Cooper McGuinness ,  Manish Giri ,  Chantelle Elizabeth Domingue ,  Melinda M. Valencia ,  Jeremy Sells

    IPC: G01N27/02 ,  B01L3/00 ,  A61B5/145 ,  A61B5/1477 ,  A61B5/00

    Abstract: A diagnostic cassette includes a substrate, to physically and electrically connect the product to a computing device, a reservoir defined within the substrate to receive a fluid sample for processing by the diagnostic cassette, a reagent to react with the fluid sample deposited in the reservoir to form a solution to enable processing of the fluid sample by the diagnostic cassette, a channel to direct the solution, and a sensor to measure a number of parameters of the solution passing through the channel. A method for measuring microfluidic samples includes receiving, in a reservoir, a fluid sample to be measured, combining the fluid sample with a reagent to create a solution, moving the solution through a channel, and measuring the solution, using sensors, as the solution passes through the channel.

    Microfluidic sensing
    45.
    发明授权
    Microfluidic sensing 有权

    公开(公告)号：US11366051B2

    公开(公告)日：2022-06-21

    申请号：US15546342

    申请日：2015-01-30

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Jeremy Sells ,  Nick McGuinness ,  Chantelle Domingue ,  Manish Giri

    IPC: G01N15/10 ,  B01L3/00

    Abstract: A device including a microfluidic channel structure formed on a substrate and including a first channel and a fluid actuator within the microfluidic channel structure. A sense region within the first channel is to receive a fluid flow of target biologic particles for counting in a single file pattern, with the sense region having a volume on a same order of magnitude as a volume of a single one of the target biologic particles.

    Blood characteristic measurement
    46.
    发明授权
    Blood characteristic measurement 有权

    公开(公告)号：US11112400B2

    公开(公告)日：2021-09-07

    申请号：US15749116

    申请日：2016-03-07

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： Shameed Sait M A ,  Rachel M. White ,  Chantelle Domingue ,  Manish Giri

    IPC: G01N33/49 ,  G01N27/02 ,  G01N33/561 ,  C12Q1/56 ,  G01N33/86

    Abstract: Examples herein provide a method. The method includes applying an electrical potential difference over a blood sample in a testing cassette of a microfluidic device, the cassette including a microfluidic channel through which the blood sample flows. The method includes measuring, over a duration of time, an electrical signal passing through the blood sample as the blood sample flows from a first end and coagulates at a second end of the microfluidic channel to obtain a measurement function as a function of time. The method also includes correlating the measurement function to a characteristic of the blood sample.

    Substrate assembly and related methods
    49.
    发明授权
    Substrate assembly and related methods 有权

    公开(公告)号：US11008214B2

    公开(公告)日：2021-05-18

    申请号：US16094411

    申请日：2016-07-22

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： Sadiq Bengali ,  Manish Giri

    IPC: B81C1/00 ,  B01L3/00 ,  B81B1/00

    Abstract: Example sensor apparatus for microfluidic devices and related methods are disclosed. In examples disclosed herein, a method of fabricating a sensor apparatus for a microfluidic device includes etching a portion of an intermediate layer to form a sensor chamber in a substrate assembly, where the substrate assembly has a base layer and the intermediate layer, and where the base layer comprises a first material and the intermediate layer comprises a second material different than the first material. The method includes forming a first electrode and a second electrode in the sensor chamber. The method also includes forming a fluidic transport channel in fluid communication with the sensor chamber, where the fluidic transport channel comprises a third material different than the first material and the second material.

    Microfluidics sensing system
    50.
    发明授权
    Microfluidics sensing system 有权

    公开(公告)号：US10702867B2

    公开(公告)日：2020-07-07

    申请号：US15521230

    申请日：2015-06-29

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Joshua M. Yu ,  Matthew David Smith ,  Shameed Sait M A ,  Manish Giri

    IPC: B01L3/00 ,  G01N35/00 ,  G01N33/487 ,  G16H10/40

    Abstract: Example implementations relate to a microfluidics sensing system. For example, a microfluidics sensing system may include a portable computing device to execute a microfluidics application, a microfluidic chip coupled to the portable computing device, the microfluidic chip including a microfluidic pumping and sensing region to perform a test on a biologic sample, and a printed circuit board (PCB) on a microfluidic reader to instruct the microfluidic pumping and sensing region to perform the test based on a command received from the microfluidics application.

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