NANOEMULSION VACCINES
    43.
    发明申请

    公开(公告)号:US20100316673A1

    公开(公告)日:2010-12-16

    申请号:US12816956

    申请日:2010-06-16

    IPC分类号: A61K39/155 A61P31/14

    摘要: The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides immunogenic nanoemulision compositions and methods of using the same to induce immune responses (e.g., immunity (e.g., protective immunity)) against a pathogenic virus of the paramyxoviridae family (e.g., a Paramyxovirinae virus (e.g., Paramyxovirus, Rubulavirus and/or Morbillivirus) and/or a Pneumovirinae virus (e.g., respiratory syncytial virus))). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.

    摘要翻译: 本发明提供了用于刺激免疫应答的方法和组合物。 具体而言,本发明提供了免疫原性纳米制剂组合物及其使用方法来诱导针对副粘病毒科家族的病原性病毒(例如,副粘病毒病毒(例如副粘病毒,Rubulavirus)的免疫应答(例如,免疫(例如保护性免疫) 和/或莫疹病毒)和/或肺炎链球菌病毒(例如呼吸道合胞病毒)))。 本发明的组合物和方法尤其可用于临床(例如治疗和预防性药物(例如疫苗接种))和研究应用。

    NANOEMULSION THERAPEUTIC COMPOSITIONS AND METHODS OF USING THE SAME
    44.
    发明申请
    NANOEMULSION THERAPEUTIC COMPOSITIONS AND METHODS OF USING THE SAME 审中-公开
    纳米结构治疗组合物及其使用方法

    公开(公告)号:US20100092526A1

    公开(公告)日:2010-04-15

    申请号:US12567470

    申请日:2009-09-25

    摘要: The present invention relates to therapeutic nanoemulsion compositions and to methods of utilizing the same. In particular, nanoemulsion compositions are described herein that find use in the treatment and/or prevention of infection (e.g., respiratory infection (e.g., associated with cystic fibrosis)), in burn wound management, and in immunogenic compositions (e.g., comprising a Burkholderia antigen) that generate an effective immune response (e.g., against a bacterial species of the genus Burkholderia) in a subject administered the immunogenic composition. Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine), industrial, and research applications.

    摘要翻译: 本发明涉及治疗性纳米乳剂组合物及其利用方法。 特别地,本文描述了用于治疗和/或预防感染(例如,呼吸道感染(例如,与囊性纤维化相关)),烧伤伤口管理和免疫原性组合物(例如,包含伯克霍尔德氏菌(Burkholderia))的纳米乳剂组合物 抗原),其在施用免疫原性组合物的受试者中产生有效的免疫应答(例如,针对伯克霍尔德氏菌属的细菌物种)。 本发明的组合物和方法尤其可用于临床(例如治疗和预防性药物),工业和研究应用。

    Compositions and methods for bacillus anthracis vaccination
    49.
    发明申请
    Compositions and methods for bacillus anthracis vaccination 审中-公开
    炭疽芽孢杆菌接种的组合物和方法

    公开(公告)号:US20150266933A1

    公开(公告)日:2015-09-24

    申请号:US11786861

    申请日:2007-04-13

    IPC分类号: C07K14/32

    摘要: The present invention relates to methods and compositions for stimulating an immune response. Specifically, the present invention provides methods of inducing an immune response to bacteria of the genus Bacillus (e.g., Bacillus anthracis) in a subject (e.g., a human subject) and compositions useful in such methods (e.g., a nanoemulsion comprising Bacillus anthracis or an immunogenic portion thereof). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination) and research applications.

    摘要翻译: 本发明涉及用于刺激免疫应答的方法和组合物。 具体地,本发明提供了在受试者(例如,人类受试者)中诱导针对芽孢杆菌属(例如,炭疽杆菌)的细菌的免疫应答的方法和可用于这些方法的组合物(例如,包含炭疽芽孢杆菌或 其免疫原性部分)。 本发明的组合物和方法尤其可用于临床(例如治疗和预防性药物(例如,疫苗接种)和研究应用)。