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57 条记录 (耗时 0.035 秒)

    Antibodies to human gastrin-releasing peptide precursor and use thereof
    41.
    发明授权
    Antibodies to human gastrin-releasing peptide precursor and use thereof 失效
    人胃泌素释放肽前体的抗体及其用途

    公开(公告)号：US5550026A

    公开(公告)日：1996-08-27

    申请号：US15180

    申请日：1993-02-11

    申请人： Ken Yamaguchi ,  Yoshio Miyake

    发明人： Ken Yamaguchi ,  Yoshio Miyake

    IPC分类号： C07K14/575 ,  C07K16/26 ,  G01N33/53 ,  C12N5/12

    CPC分类号： C07K16/26 ,  C07K14/57572

    摘要： Antibodies made to a flanking region GPR(31-8) in human gastrin-releasing peptide (GRP) precursor. Since the antibodies have high affinity to GRP precursor, and the GPR precursor is highly stable in the blood, then lung cancer, especially small cell lung cancer can be diagnosed with high reliability by detecting or measuring GRP precursor in the blood of a patient using the present antibodies.

    摘要翻译： 针对人胃泌素释放肽（GRP）前体中的侧翼区GPR（31-8）制备的抗体。 由于抗体对GRP前体具有高亲和力，并且GPR前体在血液中高度稳定，因此通过使用以下方法检测或测量患者血液中的GRP前体，可以高度可靠地诊断肺癌，特别是小细胞肺癌 目前的抗体。

    Cowling assembly for motorcycles
    42.
    发明授权
    Cowling assembly for motorcycles 失效
    汽车摩托车组装

    公开(公告)号：US4911494A

    公开(公告)日：1990-03-27

    申请号：US208140

    申请日：1988-06-16

    申请人： Akira Imai ,  Takahisa Suzuki ,  Kenichi Nishimoto ,  Ken Yamaguchi

    发明人： Akira Imai ,  Takahisa Suzuki ,  Kenichi Nishimoto ,  Ken Yamaguchi

    IPC分类号： B62J17/02 ,  B62J17/00 ,  B62J23/00 ,  B62J99/00

    CPC分类号： B62J17/00

    摘要： A cowling assembly is mounted on a front portion of the frame of a motorcycle. The cowling assembly includes a cowling covering a front portion of the frame, a windshield disposed on and continuously blending into a central upper portion of the cowling, and a pair of air ducts extending along laterally opposite sides of the windshield and having an air inlet for introducing an air flow developed when the motorcycle is running into the cowling and an air outlet for discharging the air flow introduced from the air inlet in a substantially upward direction. The air inlet is positioned near a lower end of the windshield on each side of the cowling, and the air outlet is positioned at an upper end of the cowling.

    摘要翻译： 整流罩组件安装在摩托车的框架的前部。 整流罩组件包括覆盖框架的前部的整流罩，设置在并连续地混合到整流罩的中心上部的挡风玻璃以及沿挡风玻璃的横向相对侧延伸的一对空气导管，并且具有用于 引入当摩托车进入整流罩时产生的空气流和用于排出从空气入口沿大致向上的方向引入的空气流的空气出口。 进气口位于罩盖两侧的挡风玻璃下端附近，出风口位于整流罩的上端。

    Semiconductor device
    43.
    发明授权
    Semiconductor device 失效
    半导体器件

    公开(公告)号：US4769686A

    公开(公告)日：1988-09-06

    申请号：US63785

    申请日：1987-06-19

    申请人： Masatada Horiuchi ,  Ken Yamaguchi

    发明人： Masatada Horiuchi ,  Ken Yamaguchi

    IPC分类号： H01L21/225 ,  H01L21/336 ,  H01L21/8238 ,  H01L27/092 ,  H01L29/08 ,  H01L29/45 ,  H01L29/78

    CPC分类号： H01L29/66575 ,  H01L21/2257 ,  H01L21/823835 ,  H01L27/0927 ,  H01L29/0847 ,  H01L29/41783 ,  H01L29/456 ,  H01L29/66628

    摘要： Herein disclosed is a semiconductor device, especially, an MISFET which can ensure a high breakdown voltage and operate at a high speed. The semiconductor device according to the present invention reduces the sheet resistance by using an impurity region, which has an impurity concentration not exceeding 10.sup.20 cm.sup.-3, in a drain or source region and by forming a metal silicide layer on the surface of the impurity region. Moreover, the semiconductor device of the present invention is constructed such that the impurity concentration of an n-type drain or source region does not exceed 10.sup.20 cm.sup.-3 whereas the impurity concentration of a p-type drain or source region does not exceed 10.sup.19 cm.sup.-3 and such that at least one portion of the drain or source region is made of a metal silicide so that it can effectively protect the latch-up phenomenon which is caused when two or more semiconductor devices of different conductive type are integrated.

    摘要翻译： 这里公开的是半导体器件，特别是能够确保高击穿电压并以高速运行的MISFET。 根据本发明的半导体器件通过在漏极或源极区域中使用杂质浓度不超过1020cm -3的杂质区域并且在杂质区域的表面上形成金属硅化物层来降低薄层电阻 。 此外，本发明的半导体器件被构造成使得n型漏极或源极区域的杂质浓度不超过1020cm -3，而p型漏极或源极区域的杂质浓度不超过1019cm -3，并且使得漏极或源极区域的至少一部分由金属硅化物制成，使得其可以有效地保护当两个或更多个不同导电类型的半导体器件集成时引起的闩锁现象。

    Double swing-arm motorcycle frame
    44.
    发明授权
    Double swing-arm motorcycle frame 失效
    双摆臂摩托车架

    公开(公告)号：US4721179A

    公开(公告)日：1988-01-26

    申请号：US919160

    申请日：1986-10-15

    申请人： Ken Yamaguchi ,  Akio Kawano ,  Keiji Ono

    发明人： Ken Yamaguchi ,  Akio Kawano ,  Keiji Ono

    IPC分类号： B62K25/24 ,  B62K25/26

    CPC分类号： B62K25/24 ,  B62K25/26

    摘要： A motorcycle frame in which both the front and rear wheels are supported by respective pairs of swing arms pivotally supported by two side frames. Each side frame has a front and a rear bracket and a connecting structure extending upwardly and longitudinally over the engine. The connecting structure may be integral with both of the brackets or may be a pipe frame bolted to the brackets.

    摘要翻译： 一种摩托车车架，其中前轮和后轮都由相应的由两个侧框枢转支承的摆臂支承。 每个侧框架具有前和后支架以及在发动机上向上和纵向延伸的连接结构。 连接结构可以与两个支架一体，也可以是螺栓连接到支架上的管道框架。

    Motorcycle radiator
    45.
    发明授权
    Motorcycle radiator 失效
    摩托车散热器

    公开(公告)号：US4660624A

    公开(公告)日：1987-04-28

    申请号：US541450

    申请日：1983-10-13

    申请人： Ken Yamaguchi

    发明人： Ken Yamaguchi

    IPC分类号： B62J99/00 ,  F28D1/047 ,  F28D1/053 ,  F28D7/08 ,  F28F1/02 ,  F28F1/00

    CPC分类号： F28D1/05383 ,  F28D1/0471 ,  F28D1/05366 ,  F28D7/08 ,  F28F1/02 ,  F28D2001/0273

    摘要： A radiator for a motorcycle having a core with an arcuate front surface. The radiator tanks remain parallel. The radiator is retained by means of a pin and fastener means nonconcentrically arranged to insure proper mounting under heavy load road conditions. The tubes of the core may be arranged in either vertical or horizontal extension and may be arcuate to define the concave front surface of the core. Straight tubes of varying width may also be employed to define the arcuate front surface.

    摘要翻译： 一种用于具有弓形前表面的芯的摩托车的散热器。 散热器箱保持平行。 散热器通过销和紧固装置保持非集中布置，以确保在重载路况下的正确安装。 芯的管可以布置成垂直或水平延伸，并且可以是弧形的，以限定芯的凹形前表面。 也可以使用不同宽度的直管来限定弓形前表面。

    Motorcycle
    46.
    发明授权
    Motorcycle 失效
    摩托车

    公开(公告)号：US4641721A

    公开(公告)日：1987-02-10

    申请号：US780579

    申请日：1985-09-26

    申请人： Ken Yamaguchi

    发明人： Ken Yamaguchi

    IPC分类号： B62J99/00 ,  B60K11/04 ,  B62K11/00 ,  B62K11/04 ,  B62K19/40 ,  B62M7/02 ,  F01P11/00 ,  F02B61/02 ,  F02B75/22

    CPC分类号： F02B75/22 ,  B60K11/04 ,  B62K11/00 ,  F01P11/00 ,  F02B61/02

    摘要： A motorcycle includes a frame and a front fork connected to the frame and disposed in opposed relation to the front portion of the frame, and an engine mounted on the frame. A radiator is connectable to a fluid circulating system operatively associated with the engine for cooling a fluid flowing through the circulating system. The radiator includes a generally vertically-disposed body pivotally connected at an upper portion thereof to the front portion of the frame for angular movement between an operative position where the radiator body is disposed adjacent to the front portion of the frame and an inoperative position where the radiator body is away from the front portion. Retaining means is formed on the front portion of the frame and disposed at a level lower than the upper portion of the radiator body, the retaining means being engageable with the radiator body when the radiator body is in its operative position to releaseably hold the radiator body against angular movement.

    摘要翻译： 摩托车包括框架和连接到框架并与框架的前部相对设置的前叉和安装在框架上的发动机。 散热器可连接到与发动机可操作地相关联的流体循环系统，用于冷却流过循环系统的流体。 散热器包括大致垂直设置的主体，其在其上部处枢转地连接到框架的前部，用于在散热器主体邻近框架的前部部分设置的操作位置和非工作位置之间进行角运动， 散热器主体远离前部。 保持装置形成在框架的前部并且设置在比散热器主体的上部更低的水平面处，当散热器主体处于其工作位置时，保持装置可与散热器主体接合，以可释放地保持散热器主体 对角运动。

    Search for cancer markers by a novel screening method
    48.
    发明授权
    Search for cancer markers by a novel screening method 失效
    通过新的筛选方法寻找癌症标志物

    公开(公告)号：US07868137B2

    公开(公告)日：2011-01-11

    申请号：US11704252

    申请日：2007-02-09

    申请人： Kazuki Sasaki ,  Kae Sato ,  Ken Yamaguchi

    发明人： Kazuki Sasaki ,  Kae Sato ,  Ken Yamaguchi

    IPC分类号： A61K38/00

    CPC分类号： G01N33/574 ,  C07K14/47 ,  C07K14/4748 ,  C07K14/705 ,  C07K16/30 ,  C07K16/303 ,  Y10T436/141111

    摘要： The present invention relates to a method of concentrating low molecular weight peptides in the supernatant of serum-free cultured cells, said method comprising allowing the peptides to bind to a strong cation exchanger under an acid condition, and eluting them under an alkali condition to concentrate the peptide. Furthermore, peptides having the amino acid sequence as set forth in SEQ ID NO: 1 or 2, and a method of screening cancer markers using antibody to these peptides, are disclosed.

    摘要翻译： 本发明涉及在无血清培养细胞的上清液中浓缩低分子量肽的方法，所述方法包括使肽在酸性条件下与强阳离子交换剂结合，并在碱性条件下将其洗脱以浓缩 肽。 此外，公开了具有SEQ ID NO：1或2所示的氨基酸序列的肽以及使用这些肽的抗体筛选癌症标记物的方法。