公开(公告)号：US07825083B2

公开(公告)日：2010-11-02

申请号：US11055331

申请日：2005-02-10

申请人： Andrew Carter

发明人： Andrew Carter

IPC分类号： C07K14/78 ,  A61K38/00

CPC分类号： A61F2/30742 ,  A61B17/06166 ,  A61F2/30756 ,  A61F2/30767 ,  A61F2/4601 ,  A61F2/4618 ,  A61F2002/30673 ,  A61F2002/30678 ,  A61F2002/30736 ,  A61F2310/00365 ,  A61L27/227

摘要： A composite tissue formed in situ is provided. The composite tissue includes a synovial joint tissue; and a barrier material adhered thereto for sealing the synovial joint tissue against synovial fluid. Also provided is a method for regenerating synovial joint tissue in situ by excluding synovial fluid therefrom. The method includes providing a synovial joint tissue having a defect; and placing a barrier material in intimate contact with the defect for sealing the defect against synovial fluid. The barrier material includes a curable protein copolymer. The method further includes curing the protein copolymer in situ. The barrier material can include a crosslinked network, or a self gelled network of repeating elastin-like and fibroin-like polymer chains.

摘要翻译： 提供了原位形成的复合组织。 复合组织包括滑膜关节组织; 以及粘附到其上的阻挡材料，用于密封滑液关节组织以抵抗滑液。 还提供了通过从其中排除滑液来原位再生滑液关节组织的方法。 该方法包括提供具有缺陷的滑膜关节组织; 并且将阻挡材料与缺陷紧密接触以将缺陷密封以防止滑液。 阻隔材料包括可固化的蛋白质共聚物。 该方法还包括原位固化蛋白质共聚物。 阻挡材料可以包括交联网络或重复弹性蛋白样和丝心蛋白样聚合物链的自凝胶网络。

公开(公告)号：US07806914B2

公开(公告)日：2010-10-05

申请号：US10749640

申请日：2003-12-31

申请人： Lawrence M. Boyd ,  Tyler P. Lipschultz ,  Mark D. LoGuidice ,  Andrew Carter

发明人： Lawrence M. Boyd ,  Tyler P. Lipschultz ,  Mark D. LoGuidice ,  Andrew Carter

IPC分类号： A61B17/88

CPC分类号： A61B17/8685 ,  A61B17/7007 ,  A61B17/701 ,  A61B17/7032 ,  A61B17/7034 ,  A61B17/7037 ,  A61B17/7053 ,  A61B17/8605 ,  A61B17/864 ,  A61B17/866 ,  A61B17/869 ,  A61B2090/031 ,  A61F2/442 ,  A61F2002/444

摘要： A dynamic stabilization construct for implantation within the spine comprises bone anchors that include a flexible portion between the bone engaging and head portions of the anchor. The head portion is configured to mate with different types of stabilization elements adapted to span between spinal motion segments. The engagement portion can also be configured for different types of fixation to a motion segment, such as within the pedicle of a vertebra. The flexible portion permits limited bending of the bone anchor beneath the level of the stabilization element. In one embodiment, the flexible portion is integrated into the body of the bone anchor in the form of hinge elements. In another embodiment, a separate flexible element, such as a spacer or spring, is interposed between the head and engagement portions. In a further embodiment, the bone anchor includes a portion having a reduced cross-section. The flexible bone anchors may be used to tailor the dynamic flexibility of spinal stabilization instrumentation at each level of the construct.

摘要翻译： 用于在脊柱内植入的动态稳定构造包括骨锚，其包括在骨接合和锚的头部之间的柔性部分。 头部构造成与适于跨越脊椎运动段之间的不同类型的稳定元件配合。 接合部分还可以被配置用于不同类型的固定到运动段，例如在椎骨的椎弓根内。 柔性部分允许骨锚固件在稳定元件的水平面下方受到有限的弯曲。 在一个实施例中，柔性部分以铰链元件的形式集成到骨锚固体的主体中。 在另一个实施例中，单独的柔性元件（例如间隔件或弹簧）插入在头部和接合部分之间。 在另一实施例中，骨锚包括具有减小的横截面的部分。 灵活的骨锚可用于定制每个结构水平的脊柱稳定器械的动态灵活性。

公开(公告)号：US20100232211A1

公开(公告)日：2010-09-16

申请号：US12789691

申请日：2010-05-28

申请人： Hongyue Liu ,  Yong Lu ,  Andrew Carter ,  Yiran Chen ,  Hai Li

发明人： Hongyue Liu ,  Yong Lu ,  Andrew Carter ,  Yiran Chen ,  Hai Li

IPC分类号： G11C11/00 ,  G11C7/02 ,  G11C7/00

CPC分类号： G11C7/14 ,  G11C11/1673

摘要： The present disclosure relates to memory arrays with read reference voltage cells. In particular the present disclosure relates to variable resistive memory cell apparatus and arrays that include a high resistance state reference memory cell and a low resistance state reference memory cell that provides a reliable average reference voltage on chip to compare to a read voltage of a selected memory cell and determine if the selected memory cell is in the high resistance state or low resistance state. These memory arrays are particularly suitable for use with spin-transfer torque memory cells and resolves many systematic issues related to generation of a reliable reference voltage.

公开(公告)号：US07716076B1

公开(公告)日：2010-05-11

申请号：US11023048

申请日：2004-12-27

申请人： Robert J. Block ,  Andrew Carter

发明人： Robert J. Block ,  Andrew Carter

IPC分类号： G06Q40/00

CPC分类号： G06Q40/08

摘要： A method for structuring an insurance transaction. The method includes providing insurance coverage to reimburse an insured entity in the event that the insured entity incurs a loss based on the occurrence of one or more defined events, designating an insurance premium amount to be paid by the insured entity as an insurance premium. The method further includes requiring that the insurance premium amount be paid, at least in part, by a transfer of intellectual property assets, each intellectual property asset including a plurality of intellectual property rights.

摘要翻译： 一种构建保险交易的方法。 如果被保险人根据一个或多个定义事件的发生而导致损失，指定被保险实体作为保险费支付的保险费金额，则提供保险范围以偿还被保险实体。 该方法还包括要求至少部分通过转让知识产权资产，每种知识产权资产包括多种知识产权来支付保险费。

公开(公告)号：US20060064367A1

公开(公告)日：2006-03-23

申请号：US10947379

申请日：2004-09-23

申请人： Robert Block ,  Andrew Carter

发明人： Robert Block ,  Andrew Carter

IPC分类号： G06Q40/00

CPC分类号： G06Q40/00 ,  G06Q40/08 ,  G06Q40/10

摘要： A method is performed by an insurance transaction workstation for structuring an insurance transaction between an insured entity owning an intellectual property holding company (IPHC) and an insurer. The method includes receiving an insurance coverage request for protection against a loss based on a successful taxing authority challenge to tax benefits or value derived from the IPHC, calculating a probability of success of the taxing authority challenge, and identifying an intellectual property (IP) portfolio owned by the IPHC. The method further includes estimating a current value of IP assets in the identified IP portfolio and determining an insurance premium of an insurance policy based on the received insurance coverage, the calculated probability of success, and the current value of the IP assets.

摘要翻译： 保险交易工作站执行一种方法，用于在拥有知识产权控股公司（IPHC）的被保险实体与保险公司之间构建保险交易。 该方法包括根据成功的征税机构对税收优惠或从IPHC获得的价值的挑战，计算征税机构挑战的成功概率以及识别知识产权（IP）投资组合，收到保护报酬请求以防止损失 由IPHC拥有。 该方法还包括估计所识别的知识产权组合中的知识产权资产的当前价值，并根据所接收的保险范围，所计算的成功概率和知识产权资产的当前价值确定保险单的保险费。

公开(公告)号：US20050123242A1

公开(公告)日：2005-06-09

申请号：US10501807

申请日：2003-01-20

申请人： Robert Walker ,  Andrew Carter

发明人： Robert Walker ,  Andrew Carter

IPC分类号： G02F1/21 ,  G02F1/225 ,  G02B6/26

CPC分类号： G02F1/2257 ,  G02F1/218 ,  G02F1/2255 ,  G02F2001/212 ,  G02F2201/126 ,  G02F2202/101

摘要： A Mach-Zehnder interferometer modulator for modulating a beam of laser light includes a pair of separate waveguides (115, 116) through which the laser light is passed after splitting in a splitting zone and after which the light is recombined in a merge zone, the waveguides being formed of a material having electro-optic properties and there being provided opposed pairs of electrodes (120, 114a, 121, 114b) electrically located so as to be able to effect optical changes within the material of the waveguides. The waveguides are formed in a semiconductor material with one of the electrodes of each pair being formed in a doped layer (114), the doped layer being of relatively high conductivity compared to the semiconductor material, buried within or below the waveguide material whilst the other electrode, the top electrode (120, 121), is a surface metalisation. The doped layer is trenched (117) so that adjacent electrodes in the doped layer are electrically isolated from one another so that one of the electrodes in the doped layer (114a) can be connected with a different electrical polarity to the other electrode in the doped layer (114b) thereby permitting the connection of the pairs of electrodes in parallel anti-phase mode.

摘要翻译： 用于调制激光束的马赫 - 策德尔干涉仪调制器包括一对单独的波导（115,116），激光在分裂区域中分裂之后通过该波导通过，之后光在合并区域中重新结合， 波导由具有电光特性的材料形成，并且设置有相对的电极对（120,114a，121,114b），以使得能够影响波导材料内的光学变化。 波导形成在半导体材料中，每对电极中的一个电极被形成在掺杂层（114）中，掺杂层与半导体材料相比具有相对较高的导电性，掩埋在波导材料内或下方，而另一个 电极，顶部电极（120,121）是表面金属化。 掺杂层被沟槽化（117），使得掺杂层中的相邻电极彼此电隔离，使得掺杂层（114a）中的电极中的一个可以以不同的电极性连接到另一个电极 掺杂层（114b），从而允许以平行的反相模式连接成对的电极。

公开(公告)号：US08123707B2

公开(公告)日：2012-02-28

申请号：US12818452

申请日：2010-06-18

申请人： James William Huckle ,  Andrew Carter ,  Nicolas J. Cotton ,  William R Walsh ,  Nelson Scarborough ,  Roger J. Talish

发明人： James William Huckle ,  Andrew Carter ,  Nicolas J. Cotton ,  William R Walsh ,  Nelson Scarborough ,  Roger J. Talish

IPC分类号： A61H1/00

CPC分类号： A61N7/00 ,  A61B17/16 ,  A61B18/20 ,  A61N2007/0078

摘要： The invention relates to methods and apparatus for therapeutically treating connective tissue or increasing vascularization in tissue using ultrasound. More particularly, the present invention relates to methods and apparatus which use ultrasound to stimulate growth or healing, or to treating pathologies, of connective tissue, or to increase vascularization in ischaemic or grafted tissue using ultrasound.

摘要翻译： 本发明涉及用于使用超声治疗结缔组织或增加组织血管化的方法和装置。 更具体地说，本发明涉及使用超声波来刺激生长或愈合，或治疗结缔组织的病理学，或使用超声波增加缺血或移植组织血管形成的方法和装置。

公开(公告)号：US20060178743A1

公开(公告)日：2006-08-10

申请号：US11055331

申请日：2005-02-10

申请人： Andrew Carter

发明人： Andrew Carter

IPC分类号： A61F2/08 ,  A61F2/28

CPC分类号： A61F2/30742 ,  A61B17/06166 ,  A61F2/30756 ,  A61F2/30767 ,  A61F2/4601 ,  A61F2/4618 ,  A61F2002/30673 ,  A61F2002/30678 ,  A61F2002/30736 ,  A61F2310/00365 ,  A61L27/227

摘要： A composite tissue formed in situ is provided. The composite tissue includes a synovial joint tissue; and a barrier material adhered thereto for sealing the synovial joint tissue against synovial fluid. Also provided is a method for regenerating synovial joint tissue in situ by excluding synovial fluid therefrom. The method includes providing a synovial joint tissue having a defect; and placing a barrier material in intimate contact with the defect for sealing the defect against synovial fluid. The barrier material includes a curable protein copolymer. The method further includes curing the protein copolymer in situ. The barrier material can include a crosslinked network, or a self gelled network of repeating elastin-like and fibroin-like polymer chains.

摘要翻译： 提供了原位形成的复合组织。 复合组织包括滑膜关节组织; 以及粘附到其上的阻挡材料，用于密封滑液关节组织以抵抗滑液。 还提供了通过从其中排除滑液来原位再生滑液关节组织的方法。 该方法包括提供具有缺陷的滑膜关节组织; 并且将阻挡材料与缺陷紧密接触以将缺陷密封以防止滑液。 阻隔材料包括可固化的蛋白质共聚物。 该方法还包括原位固化蛋白质共聚物。 阻挡材料可以包括交联网络或重复弹性蛋白样和丝心蛋白样聚合物链的自凝胶网络。

公开(公告)号：US20060039420A1

公开(公告)日：2006-02-23

申请号：US10506001

申请日：2003-02-28

申请人： Steven Borley ,  Andrew Carter

发明人： Steven Borley ,  Andrew Carter

IPC分类号： H01S3/10

CPC分类号： H01S5/06256 ,  H01S5/0425 ,  H01S5/1206 ,  H01S5/1215 ,  H01S5/1218

摘要： A control (20) and a method of controlling a tunable laser having a gain section (4), a phase change section (5) and a segmented Bragg grating reflector section (6) comprising a series of grating units (9-17) each of a different pitch, and an electrode (9a-17a) associated with each grating so that an electrical current is applicable to each individual grating. The control (20) includes a plurality of digitally controlled sources (31, 32) of electrical current which are each connected to switch means (33 or 35, 36) operable to independently connect each of said sources (31, 32) to a respective electrode (e.g. 11a or 12a) associated with a grating (e.g. 11 or 12) which is one of a subset of consecutive gratings (e.g. 11 & 12) selected from said series of grating units (9-17).

摘要翻译： 一种控制（20）和一种控制具有增益部分（4），相变部分（5）和分段布拉格光栅反射器部分（6）的可调谐激光器的方法，每个部分包括一系列光栅单元（9-17） 以及与每个光栅相关联的电极（9a-17a），使得电流可应用于每个单独的光栅。 控制器（20）包括多个数字控制的电流源（31,32），每个电流源均连接到可操作以将每个所述源（31,32）独立地连接到相应的开关装置（33,35,36） 与从所述系列光栅单元（9-17）中选择的连续光栅（例如11和12）的子集中的光栅（例如11或12）相关联的电极（例如11a或12a）。

公开(公告)号：US20050064011A1

公开(公告)日：2005-03-24

申请号：US10955368

申请日：2004-09-30

申请人： Young-Ho Song ,  Andrew Carter

发明人： Young-Ho Song ,  Andrew Carter

IPC分类号： A61L27/54 ,  A61L29/16 ,  A61L31/16 ,  A61F2/00

CPC分类号： A61L29/085 ,  A61L27/54 ,  A61L29/16 ,  A61L31/10 ,  A61L31/143 ,  A61L31/16 ,  A61L2300/216 ,  A61L2300/606 ,  A61L2300/608 ,  A61L2300/802 ,  C08L53/02

摘要： A vascular medical device is provided, which contains at least one phenolic compound. The medical device also contains at least one polymeric region, which regulate the release of the phenolic compound from the device. The polymeric region, in turn, contains at least one polymer species. In some embodiments, for example, the polymeric region contains a vinyl aromatic polymer species (e.g., a styrene homopolymer or copolymer). In other embodiments, for example, the polymeric region contains an alkene polymer species (e.g., an isobutylene homopolymer or copolymer). In still other embodiments, for example, the polymeric region contains a biostable polymer having at least one Tg below 25° C. (e.g., a homopolymer or copolymer containing one or more polyalkene polymer blocks).

摘要翻译： 提供了含有至少一种酚类化合物的血管医疗装置。 医疗装置还包含至少一个聚合物区域，其调节酚类化合物从该装置的释放。 聚合物区域又包含至少一种聚合物种类。 在一些实施方案中，例如，聚合物区域含有乙烯基芳族聚合物物质（例如苯乙烯均聚物或共聚物）。 在其它实施方案中，例如，聚合物区域含有烯烃聚合物物质（例如，异丁烯均聚物或共聚物）。 在其它实施方案中，例如，聚合物区域含有至少一个Tg低于25℃的生物稳定聚合物（例如含有一个或多个聚烯烃聚合物嵌段的均聚物或共聚物）。