公开(公告)号：US20050228169A1

公开(公告)日：2005-10-13

申请号：US10508190

申请日：2003-03-19

申请人： Hiroshi Yokota ,  Kazuki Satoh

发明人： Hiroshi Yokota ,  Kazuki Satoh

IPC分类号： A61P25/00 ,  C07K14/47 ,  C12N1/19 ,  C12N1/21 ,  C12N15/12 ,  G01N33/566 ,  C07K14/705 ,  C07H21/04 ,  C12Q1/68

CPC分类号： C07K14/47 ,  G01N33/566

摘要： There is provided a polypeptide that binds to syntaxin-1a and comprises the amino acid sequence shown in SEQ ID NO: 1 in the Sequence Listing, or a polypeptide having a homology of at least approximately 90% to the amino acid sequence that binds to syntaxin-1a, a partial peptide thereof, and a polynucleotide encoding any of these polypeptides or the complementary strand thereof, as well as an inhibitor, an antagonist, and an activator of physiological activity of any of the polypeptides. Further, a pharmaceutical composition that utilizes these is provided. There is also provided a method for producing the polypeptides or the peptide by genetic engineering techniques, a method for identifying the inhibitor, antagonist, or activator, and a method and a kit for diagnosing a disease with which the polypeptides are associated.

摘要翻译： 提供了结合于syntaxin-1a并且包含序列表中SEQ ID NO：1所示的氨基酸序列的多肽，或与结合于语义蛋白的氨基酸序列具有至少约90％的同源性的多肽 -1a，其部分肽和编码这些多肽或其互补链中的任何一个的多核苷酸，以及任何多肽的抑制剂，拮抗剂和活化剂。 此外，提供利用这些的药物组合物。 还提供了通过基因工程技术生产多肽或肽的方法，用于鉴定抑制剂，拮抗剂或活化剂的方法，以及用于诊断与多肽相关的疾病的方法和试剂盒。

公开(公告)号：US06703432B1

公开(公告)日：2004-03-09

申请号：US10110736

申请日：2002-08-07

申请人： Kunio Fujiwara ,  Kazuyoshi Takeda ,  Hiroshi Yokota ,  Hidenobu Arimitsu

发明人： Kunio Fujiwara ,  Kazuyoshi Takeda ,  Hiroshi Yokota ,  Hidenobu Arimitsu

IPC分类号： C08F3600

CPC分类号： B01J20/261 ,  B01D53/261 ,  B01D53/28 ,  B01J20/26

摘要： An object of the present invention is to provide a water adsorbing/desorbing organic polymer material having excellent water adsorbing/desorbing performance and which is inexpensive and readily disposable by incineration or the like. In order to attain this object, water adsorbing/desorbing organic polymer materials of the present invention are characterized by having a polymer side chain containing a hydrophilic group on the backbone of an organic polymer base.

摘要翻译： 本发明的目的是提供具有优异的吸水/脱附性能的水吸附/解吸有机聚合物材料，其通过焚烧等廉价且容易一次性。 为了达到这个目的，本发明的水吸附/解吸有机聚合物材料的特征在于在有机聚合物基体的主链上具有含有亲水基团的聚合物侧链。

公开(公告)号：US06263905B1

公开(公告)日：2001-07-24

申请号：US09284057

申请日：1999-04-06

申请人： Hiroshi Yokota ,  Shingo Yokota

发明人： Hiroshi Yokota ,  Shingo Yokota

IPC分类号： F16K3134

CPC分类号： G05D9/04 ,  F16K31/363 ,  G05D7/03 ,  G05D16/166 ,  Y10T137/7371 ,  Y10T137/7404 ,  Y10T137/7769 ,  Y10T137/7788

摘要： An automatic regulating valve apparatus comprises a main valve unit, and a pilot valve unit operatively connected to the main valve unit to control the main valve unit. The main valve unit comprises a main valve casing, a main valve element disposed in the main valve casing, and a main valve driving member disposed in the main valve casing together with the main valve element and having a pressure receiving area greater than that of the main valve element, the main valve element is disposed on the upstream side of a valve seat so as to form a restricting passage between the main valve element and the main valve seat, and the main valve driving member is disposed for sliding movement in a space defined by a cylindrical wall formed in the main valve casing so as to define a main valve driving pressure chamber together with the cylindrical wall. The pilot valve unit comprises pilot valves A and B which are operated for opening and closing operations according to the variation of a pressure difference across an orifice included in the main valve unit, a pressure difference across the main valve unit, liquid level on the downstream side of the main valve unit or the pressure on the upstream side of the main valve unit. The pilot valve A and the pilot valve B are arranged in series and connected between the upstream and the downstream side of the main valve unit by connecting passages with a chamber between the pilot valves A and B connected to the main valve driving pressure chamber. The pressure in the main valve driving pressure chamber is varied by the coordinated operations of the pilot valves A and B to regulate the opening of the main valve unit. Thus, the automatic regulating valve apparatus 4 exercises automatic control functions including a constant-flow control function, an emergency shutoff function, a liquid level control function and an upstream pressure control function.

摘要翻译： 一种自动调节阀装置，包括主阀单元和可操作地连接到主阀单元以控制主阀单元的先导阀单元。 主阀单元包括主阀壳体，设置在主阀壳体中的主阀元件和主阀驱动构件，主阀驱动构件与主阀元件一起设置在主阀壳体中，并且具有大于 主阀元件，主阀元件设置在阀座的上游侧，以在主阀元件和主阀座之间形成限制通道，主阀驱动构件设置成在空间中滑动 由形成在主阀壳体中的圆柱形壁限定，以便与圆柱形壁一起限定主阀驱动压力室。 先导阀单元包括先导阀A和B，其根据主阀单元中包括的孔口的压力差的变化，主阀单元两端的压差，下游的液位 主阀单元的侧面或主阀单元上游侧的压力。 先导阀A和先导阀B通过与连接到主阀驱动压力室的先导阀A和B之间的腔室连接通道而串联布置并连接在主阀单元的上游和下游侧之间。 主阀驱动压力室中的压力通过先导阀A和B的协调操作而变化，以调节主阀单元的打开。 因此，自动调节阀装置4执行自动控制功能，包括恒流控制功能，紧急关闭功能，液位控制功能和上游压力控制功能。

公开(公告)号：US6152689A

公开(公告)日：2000-11-28

申请号：US230251

申请日：1999-01-22

申请人： Hiroshi Yokota ,  Shingo Yokota

发明人： Hiroshi Yokota ,  Shingo Yokota

IPC分类号： F04D5/00 ,  F04D7/04 ,  F04D9/04 ,  F04D15/00 ,  F04D17/08

CPC分类号： F04D7/045 ,  F04D15/0005 ,  F04D9/04 ,  F04D9/041 ,  F05B2210/132

摘要： The invention provides a self-priming centrifugal pump capable of sucking up and pumping a highly viscous liquid containing muddy substances including a large amount of bubbles, and solid foreign matters, of preventing the flow of the liquid from the side of a main pump unit into a vacuum device and from the vacuum device into the main pump unit at all stages of operation including starting, operating and stopping stages and of perfectly automatic operation, and very economical in costs of equipment and maintenance.The self-priming centrifugal pump has a main pump unit for pumping a liquid, an auxiliary pump unit for centrifugal gas-liquid separation, and an exhaust vacuum device. A region in the vicinity of a central part of an impeller included in the main pump unit is connected via a passage having a small passage area as compared with the discharge ability of the auxiliary pump unit to the suction opening of the auxiliary pump unit, the discharge opening of the auxiliary pump unit is connected to the suction opening of the main pump unit by a return passage, and a region in the vicinity of a central part of the impeller of the auxiliary pump unit is connected via an exhaust passage to the vacuum device. The exhaust passage includes in series therein a slow-acting valve which opens with a delay after the connection of a prime mover for driving the self-priming centrifugal pump to a power source, and a quick-acting valve which closes immediately after the disconnection of the prime mover from the power source.

摘要翻译： PCT No.PCT / JP97 / 00857 Sec。 371日期1999年1月22日 102（e）日期1999年1月22日PCT 1997年3月17日PCT公布。 出版物WO98 / 04833 日期1998年2月5日本发明提供一种自吸式离心泵，其能够吸收和泵送含有大量气泡的混浊物质和固体异物的高粘性液体，以防止液体从侧面流出 主泵单元进入真空装置，并从真空装置进入主泵装置，包括启动，运行和停止阶段以及完全自动运行的各个阶段，并且设备和维护成本非常经济。 自吸离心泵具有用于泵送液体的主泵单元，用于离心气液分离的辅助泵单元和排气真空装置。 包括在主泵单元中的叶轮的中心部分附近的区域通过与辅助泵单元对辅助泵单元的吸入口的排出能力相比具有小通道面积的通道连接， 辅助泵单元的排出口通过返回通路与主泵单元的吸入口连接，辅助泵单元的叶轮的中央部附近的区域经由排气通路与真空连接 设备。 排气通道串联地包括缓慢作用的阀，其在用于将自吸离心泵驱动到动力源的原动机连接之后延迟地打开;以及快速阀，其在断开后立即关闭 来自电源的原动机。

公开(公告)号：US6033558A

公开(公告)日：2000-03-07

申请号：US424

申请日：1998-02-03

申请人： Hiroshi Yokota

发明人： Hiroshi Yokota

IPC分类号： B01D29/01 ,  B01D36/02 ,  B01D29/64 ,  B01D29/66 ,  B01D29/70

CPC分类号： B01D36/02 ,  B01D29/01 ,  B01D2201/02 ,  B01D2201/188

摘要： A self-gush-cleaning filter device comprises a filter casing (1) provided with an inlet passage (a) and an outlet passage (d), a screen (11) disposed within the filter casing (1) so as to slide along the inner surface of the filter casing (1) in the flowing direction of a fluid, a foreign matter ejecting opening (15) being formed between the screen (11) and the inlet passage (a). A drive shaft (4) for driving the screen (11), a screen driving unit (3) for driving the drive shaft (4) so as to move the screen (11) quickly in a downstream direction in which the fluid flows from the inlet passage (a) toward the outlet passage (d) and to move the screen slowly in an upstream direction. An outlet shutoff valve (14) is disposed in the outlet passage (d) of the filter casing (1). The screen driving unit (3) is actuated after closing the outlet shutoff valve (14) to move the screen (11). When the screen (11) is moved quickly in the downstream direction, the fluid gushes from the downstream side through the screen (11) into the upstream side, and the foreign matters deposited on the screen (11) are removed from the screen (11) by the force of the gushing fluid.

摘要翻译： PCT No.PCT / JP96 / 01724 Sec。 371日期1998年2月3日 102（e）1998年2月3日PCT PCT 1996年6月20日PCT公布。 出版物WO97 / 05939 日期1997年2月20日自清洗过滤器装置包括设置有入口通道（a）和出口通道（d）的过滤器壳体（1），设置在过滤器壳体（1）内的筛网（11） 为了沿着流体的流动方向沿着过滤器壳体（1）的内表面滑动，在筛网（11）和入口通道（a）之间形成异物排出口（15）。 用于驱动筛网（11）的驱动轴（4），用于驱动驱动轴（4）的屏幕驱动单元（3），以便使流体从流体流动的下游方向快速移动 入口通道（a）朝向出口通道（d）移动并沿上游方向缓慢移动筛网。 出口截止阀（14）设置在过滤器壳体（1）的出口通道（d）中。 在关闭出口截止阀（14）以移动筛网（11）之后，屏幕驱动单元（3）被致动。 当筛网（11）在下游方向上快速移动时，流体从下游侧通过筛网（11）涌入上游侧，并且沉积在筛网（11）上的异物从筛网（11）移除 ）通过冲洗液的力。

公开(公告)号：US5953308A

公开(公告)日：1999-09-14

申请号：US150596

申请日：1998-09-10

申请人： Hiroshi Yokota ,  Ryuichi Naito ,  Hiroyuki Hirano ,  Katsumi Ishii ,  Shinichi Naohara ,  Yoshifumi Tsukuda ,  Kanya Matsumoto

发明人： Hiroshi Yokota ,  Ryuichi Naito ,  Hiroyuki Hirano ,  Katsumi Ishii ,  Shinichi Naohara ,  Yoshifumi Tsukuda ,  Kanya Matsumoto

IPC分类号： G11B21/02 ,  G11B7/0037 ,  G11B7/085 ,  G11B7/095 ,  G11B7/135 ,  G11B7/14 ,  G11B11/10 ,  G11B11/105 ,  G11B21/00 ,  G11B21/12 ,  G11B25/04

CPC分类号： G11B25/043 ,  G11B21/00 ,  G11B21/12 ,  G11B7/085 ,  G11B7/08582 ,  G11B7/095 ,  G11B7/1374 ,  G11B7/14 ,  G11B7/0037

摘要： A disc player includes: a plurality of pickup devices for reading information from a disc and a plurality of guide devices arranged radiately from a center of the disc, each for radially transferring one of the pickup devices. The guide devices are arranged so that each alternate pickup device is raised or lowered toward the inner circumferential portion of the disc.

摘要翻译： 盘片播放器包括：用于从盘读取信息的多个拾取装置和从盘的中心辐射布置的多个引导装置，每个用于径向传送拾取装置之一。 引导装置被布置成使得每个替代的拾取装置朝向盘的内周部分升高或降低。

公开(公告)号：US5820742A

公开(公告)日：1998-10-13

申请号：US619670

申请日：1996-05-23

申请人： Shin-i-ti Oda ,  Toshihide Okamoto ,  Hiroshi Yokota ,  Kenjiro Hayashi ,  Kazufumi Hamabuchi ,  Toshio Mizuno

发明人： Shin-i-ti Oda ,  Toshihide Okamoto ,  Hiroshi Yokota ,  Kenjiro Hayashi ,  Kazufumi Hamabuchi ,  Toshio Mizuno

IPC分类号： C09D5/44 ,  C09D179/08 ,  C25D13/06 ,  C08L27/12 ,  C08L79/08 ,  C09D127/12

CPC分类号： C09D5/4461 ,  C09D179/08

摘要： An electrodeposition coating method characterized in that in electrodeposition coating of a water soluble composition of a polyimide precursor which is prepared by using 1,2,3,4-butanetetracarboxylic acid or its imide-forming derivative and a diamine and has a percentage of residual acid value of 30 to 3%, there is added previously a water soluble solvent selected from the group consisting of an alcoholic solvent, N-methyl-2-pyrrolidone, dimethylformamide and dimethylacetamide to the above-mentioned composition, and an electrodeposition coating agent used therefor. There can be provided the electrodeposition coating method practicable for the use of a water soluble polyimide composition which is capable of forming a uniform baked coating film having a continuous surface and being excellent in adhesivity to substrate and in toughness.

摘要翻译： PCT No.PCT / JP94 / 01624 Sec。 371日期：1996年5月23日 102（e）日期1996年5月23日PCT提交1994年9月29日PCT公布。 公开号WO95 / 09897 日期：1995年04月13日一种电沉积涂布方法，其特征在于在通过使用1,2,3,4-丁烷四羧酸或其酰亚胺形成衍生物和二胺制备的聚酰亚胺前体的水溶性组合物的电沉积涂布中， 残留酸值的百分比为30〜3％，在上述组合物中预先添加选自醇溶剂，N-甲基-2-吡咯烷酮，二甲基甲酰胺，二甲基乙酰胺的水溶性溶剂， 用于此的电沉积涂层剂。 可以提供使用能够形成具有连续表面并且对基材的粘合性和韧性优异的均匀烘烤涂膜的水溶性聚酰亚胺组合物的电沉积涂布方法。

公开(公告)号：US5735308A

公开(公告)日：1998-04-07

申请号：US582998

申请日：1996-01-23

申请人： Hiroshi Yokota ,  Shingo Yokota

发明人： Hiroshi Yokota ,  Shingo Yokota

IPC分类号： F16K1/52 ,  F16K31/12 ,  F16K51/00 ,  G05D16/06 ,  G05D16/16 ,  F16K17/22

CPC分类号： G05D16/16 ,  G05D16/0655 ,  Y10T137/7762 ,  Y10T137/7768 ,  Y10T137/777

摘要： The present invention relates to an automatic constant-pressure lift valve provided with a pilot valve unit having an A valve unit and a B valve unit, and an external control force applying means that can be simply adjusted to set a predetermined valve-outlet pressure. A main valve unit is constructed so that an abnormal rise in the valve-outlet pressure can be avoided at start and stop and continuous operation of a pumping or conveying pump facility. The automatic constant-pressure lift valve has a construction capable of easily maintaining watertightness when the line is shut off. The pilot valve unit is not provided with any fixed flow restriction regulating passage, such as a needle valve. When the main valve unit, and the A valve unit and the B valve unit of the pilot valve unit are clogged, those valves open automatically for automatic cleaning. This constant-pressure lift valve has an excellent industrial effect.

摘要翻译： PCT No.PCT / JP94 / 01432 Sec。 371日期1996年1月23日 102（e）日期1996年1月23日PCT 1994年8月31日PCT PCT。 公开号WO95 / 06834 日期：1995年3月9日本发明涉及一种具有A阀单元和B阀单元的先导阀单元的自动恒压提升阀以及外部控制力施加单元， 阀出口压力。 主阀单元被构造成使得在泵送或输送泵设备的启动和停止以及连续操作时可以避免阀出口压力的异常升高。 自动恒压提升阀具有能够在线路被切断时容易地保持水密性的结构。 先导阀单元没有设置有诸如针阀的任何固定流量限制调节通道。 当主阀单元，A阀单元和先导阀单元的B阀单元堵塞时，这些阀自动打开以进行自动清洗。 该恒压提升阀具有出色的工业效果。

公开(公告)号：US5560470A

公开(公告)日：1996-10-01

申请号：US422245

申请日：1995-04-14

申请人： Hiroshi Yokota ,  Keiji Takahashi

发明人： Hiroshi Yokota ,  Keiji Takahashi

IPC分类号： G01N33/52 ,  G01N21/78 ,  G01N35/00 ,  G01N35/04 ,  B65G47/24

CPC分类号： G01N35/00029 ,  G01N2035/00039 ,  G01N2035/00108

摘要： Disclosed is a device for discriminating the right sides of test strips in an automated analyzer for arranging the test strips such that the right sides thereof may face in one direction, which comprises: suction holes formed on a transportation stage to be aligned in the direction orthogonal to the direction that the test strips are moved, at the positions corresponding to the intervals between test pads impregnated with reagents of the test strip; and suction holes formed on a turntable disposed subsequent to the transportation stage, at the positions corresponding to the intervals between the test pads impregnated with reagents of the test strip.

摘要翻译： 公开了一种用于在自动分析仪中鉴别试纸的右侧的装置，用于布置测试条，使得其右侧可以在一个方向上面对，其包括：形成在运输台上的抽吸孔，以在正交方向上对准 在测试条移动的方向上，对应于浸渍有测试条的试剂的测试垫之间的间隔; 以及形成在设置在输送阶段之后的转盘上的吸孔，位于对应于浸渍有试纸的试剂的测试垫之间的间隔的位置。

公开(公告)号：US5420041A

公开(公告)日：1995-05-30

申请号：US125151

申请日：1993-09-23

申请人： Kazuhiko Matsushita ,  Hiroshi Yokota ,  Keiji Fujita ,  Akihiro Tsukamoto

发明人： Kazuhiko Matsushita ,  Hiroshi Yokota ,  Keiji Fujita ,  Akihiro Tsukamoto

IPC分类号： G01N21/35 ,  G01N21/3577 ,  G01N33/28 ,  G01N33/03 ,  G01N33/26

CPC分类号： G01N33/2835 ,  G01N21/3577 ,  G01N33/2888 ,  G01N21/05 ,  Y10T436/201666

摘要： A method of determining acid value with high accuracy, using an infrared spectrometer is provided, in which the absorbance is determined attributable to carboxylic group based on an infrared absorption spectrum at wave numbers around 3300 cm.sup.-1.

摘要翻译： 提供了使用红外光谱仪以高精度测定酸值的方法，其中基于在3300cm -1附近的波数处的红外吸收光谱，由羧基决定吸光度。