公开(公告)号：US09789027B2

公开(公告)日：2017-10-17

申请号：US14414305

申请日：2013-07-12

Applicant: Antares Pharma, Inc.

Inventor： Julius C. Sund ,  Kevin D. Swanson

IPC: A61B19/00 ,  A61J1/20 ,  A61J1/14 ,  A61M5/20

CPC classification number: A61J1/2096 ,  A61J1/1406 ,  A61J1/201 ,  A61J1/2044 ,  A61J1/2055 ,  A61J1/2065 ,  A61M5/2033

Abstract: A liquid-transfer adapter operatively interposable between an injector and a vial is provided. The liquid-transfer has an injector engaging portion configured for fluidly coupling to an injector and a vial coupling. The vial coupling includes a spike that has a spike axis and a tip portion configured for piercing a septum of a vial. The tip portion includes a plurality of facets that meet each other at one or more edges and at least one of the one or more edges is sloped with respect to the spike axis. The spike defines a channel extending therethrough in fluid communication with the injector engaging portion. A channel opening is defined in at least one of the facets and disposed without interrupting the edges.

公开(公告)号：US09763855B2

公开(公告)日：2017-09-19

申请号：US14806516

申请日：2015-07-22

Applicant: ICU Medical, Inc.

Inventor： Thomas F. Fangrow

IPC: A61M1/22 ,  A61J1/22 ,  A61J1/20

CPC classification number: A61J1/22 ,  A61J1/201 ,  A61J1/2075 ,  A61J1/2082 ,  A61J1/2096 ,  Y10T137/9029

Abstract: In certain embodiments, a vial adaptor comprises a housing configured to couple the adaptor with a vial, an access channel, a regulator channel, and a regulator assembly. The access channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. The regulator channel is configured to facilitate a flow of a regulating fluid from the regulator assembly to compensate for changes in volume of a medical fluid in the vial. In some embodiments, the regulator assembly includes a flexible member configured to expand and contract in accordance with changes in the volume of the medical fluid in the vial. In some embodiments, the flexible member is substantially free to expand and contract. In some embodiments, the flexible member is not partly or completely located in a rigid enclosure.

公开(公告)号：US20170239140A1

公开(公告)日：2017-08-24

申请号：US15588380

申请日：2017-05-05

Applicant: ICU Medical, Inc.

Inventor： Thomas F. Fangrow

IPC: A61J1/20 ,  A61J1/14

CPC classification number: A61J1/2048 ,  A61J1/1406 ,  A61J1/1412 ,  A61J1/201 ,  A61J1/2055 ,  A61J1/2065 ,  A61J1/2072 ,  A61J1/2075 ,  A61J1/2079 ,  A61J1/2082 ,  A61J1/2086 ,  A61J1/2089 ,  A61J1/2096 ,  A61J1/22 ,  A61J2200/10 ,  A61J2200/76

Abstract: In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.

公开(公告)号：US20170224534A1

公开(公告)日：2017-08-10

申请号：US15472551

申请日：2017-03-29

Applicant: Clearside Biomedical, Inc.

Inventor： Rafael Victor ANDINO ,  Vladimir ZARNITSYN ,  Jesse YOO ,  Christopher John BROOKS ,  Trent John KAHUTE ,  Justin William ARSENAULT ,  David Jackson TRETTIN ,  Andrew Kent BAUER ,  Stephanie Elaine LEWIS

IPC: A61F9/00 ,  A61M5/20 ,  A61M37/00 ,  A61M5/34 ,  A61M5/46 ,  A61M5/48 ,  A61J1/20 ,  A61M5/32

CPC classification number: A61F9/0017 ,  A61F2250/0007 ,  A61F2250/0069 ,  A61J1/201 ,  A61J1/2055 ,  A61J1/2096 ,  A61M5/2033 ,  A61M5/2053 ,  A61M5/31 ,  A61M5/3293 ,  A61M5/34 ,  A61M5/344 ,  A61M5/346 ,  A61M5/347 ,  A61M5/348 ,  A61M5/349 ,  A61M5/46 ,  A61M5/482 ,  A61M37/0015 ,  A61M2005/31508 ,  A61M2037/0023 ,  A61M2037/0061 ,  A61M2210/0612

Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

公开(公告)号：US09724269B2

公开(公告)日：2017-08-08

申请号：US14091603

申请日：2013-11-27

Applicant: Becton Dickinson and Company Limited

Inventor： Jesper Sjögren ,  Fredrik Ullman

IPC: A61J1/20 ,  A61M5/178

CPC classification number: A61J1/2096 ,  A61J1/201 ,  A61J1/2051 ,  A61J1/2055 ,  A61J2205/20 ,  A61M5/1782

Abstract: A fluid connector for selectively establishing fluid communication between a first medical container and a second medical container is provided. The fluid connector includes an adapter configured to removably attach to the first container. The adapter includes an access port and a cap. The connector further includes an outer sleeve connected to the adapter and a tubular body retained at least partially within the outer sleeve. The body has a proximal end connected to the adapter and a distal end connected to the second container. The fluid connector is transitionable from a first position in which the first container and the second container are in fluid isolation to a second position in which the first container and the second container are in fluid communication. At least a portion of the cap of the adapter is retained within the outer sleeve.

公开(公告)号：US20170216144A1

公开(公告)日：2017-08-03

申请号：US15493477

申请日：2017-04-21

Applicant: BECTON DICKINSON HOLDINGS PTE. LTD.

Inventor： Franck Carrel ,  Frédéric Perot

IPC: A61J1/20 ,  A61J7/04 ,  A61J1/14

CPC classification number: A61J1/2096 ,  A61J1/1406 ,  A61J1/1425 ,  A61J1/1443 ,  A61J1/201 ,  A61J1/2055 ,  A61J1/2058 ,  A61J1/2075 ,  A61J1/2082 ,  A61J7/0472 ,  A61J2205/50 ,  Y10T137/9029

Abstract: An adaptor for coupling with a vial having a collar closed by a septum, the septum having an outer surface directed towards the outside of the vial, the adaptor comprising: a gripping member for securing the adaptor to the vial, the gripping member being capable of being laterally mounted on the collar of the vial and a pierceable elastomeric piece having at least a part intended to be in contact with the outer surface of the septum when the adaptor is secured on the vial. Also, an assembly including such an adaptor and a vial.

公开(公告)号：US09707410B2

公开(公告)日：2017-07-18

申请号：US13882392

申请日：2011-11-01

Applicant: Xavier Franci ,  Philippe Dumont ,  Svein-Erik Lindgaard

Inventor： Xavier Franci ,  Philippe Dumont ,  Svein-Erik Lindgaard

IPC: A61B19/00 ,  A61N5/10 ,  B65B3/00 ,  B65B39/04 ,  A61M5/00 ,  A61J1/20 ,  A61M5/162

CPC classification number: A61N5/1007 ,  A61J1/201 ,  A61J1/2096 ,  A61M5/002 ,  A61M5/162 ,  A61M2005/1623 ,  B65B3/003 ,  B65B39/04

Abstract: A pierce and fill connector cap for a vial sealed by an elastomeric septum includes a vial collar and a needle holder. The vial collar body defines a collar aperture to be positioned in overlying registry with the septum of the vial, and the needle holder includes a needle holder body providing a means for holding an elongate needle in registry with the collar aperture. The needle holder body being moveable with respect to said vial collar between a first position spaced from the vial collar and a second position proximate the vial collar, such that a needle held by the needle holder will puncture through the vial septum.

公开(公告)号：US20170156984A1

公开(公告)日：2017-06-08

申请号：US15436642

申请日：2017-02-17

Applicant: CareFusion 303, Inc.

Inventor： George Michel MANSOUR ,  Tyler Devin PANIAN

IPC: A61J1/20 ,  A61M5/315 ,  A61J1/14

CPC classification number: A61J1/2096 ,  A61J1/1406 ,  A61J1/1468 ,  A61J1/1475 ,  A61J1/2006 ,  A61J1/201 ,  A61J1/2048 ,  A61J1/2072 ,  A61M5/31 ,  A61M5/31511 ,  A61M2005/3114 ,  A61M2005/3121 ,  A61M2005/3123 ,  B65B3/003

Abstract: A syringe includes a plunger having a plunger tube with proximal and distal ends, a center tube with a center passage that extends within the plunger tube, and a balloon disposed over the center tube and sealingly fixed to at least one of the center tube and the plunger tube. The syringe also includes a barrel having a barrel tube having proximal and distal ends and an interior configured to accept a portion of the plunger, a tip fixedly coupled to the proximal end of the barrel tube, a post fixedly attached to the tip and extending within the barrel tube toward the distal end, the tip configured to partially extend into the center passage of the plunger, and a gas passage extending from a proximal end of the tip to the distal end of the post.

公开(公告)号：US09668939B2

公开(公告)日：2017-06-06

申请号：US14375203

申请日：2013-02-01

Applicant: Becton Dickinson Holdings Pte. Ltd.

Inventor： Franck Carrel ,  Frederic Perot

IPC: A61J1/20 ,  A61J1/14 ,  A61J7/04

CPC classification number: A61J1/2096 ,  A61J1/1406 ,  A61J1/1425 ,  A61J1/1443 ,  A61J1/201 ,  A61J1/2055 ,  A61J1/2058 ,  A61J1/2075 ,  A61J1/2082 ,  A61J7/0472 ,  A61J2205/50 ,  Y10T137/9029

Abstract: An adaptor for coupling with a vial having a collar closed by a septum, the septum having an outer surface directed towards the outside of the vial, the adaptor comprising: a gripping member for securing the adaptor to the vial, the gripping member being capable of being laterally mounted on the collar of the vial and a pierceable elastomeric piece having at least a part intended to be in contact with the outer surface of the septum when the adaptor is secured on the vial. Also, an assembly including such an adaptor and a vial.

公开(公告)号：US20170135903A1

公开(公告)日：2017-05-18

申请号：US15330061

申请日：2015-01-23

Applicant: EVEON

Inventor： Arnaud Wattelier ,  Xavier Payet-Burin

IPC: A61J1/20 ,  A61J1/14

CPC classification number: A61J1/2093 ,  A61J1/1406 ,  A61J1/20 ,  A61J1/201 ,  A61J1/2017 ,  A61J1/2048 ,  A61J1/2068 ,  A61J1/2086 ,  A61J1/2096 ,  A61M5/142 ,  B65B31/02

Abstract: The invention relates to a device (1) for reconstituting a pharmaceutical composition from at least a first component contained in a first container (2A) and a second component contained in a second container (2B), comprising: a fluidic unit (100) comprising: —a first connector (101) coupled to the first container (2A), —a second connector (102) coupled to the second container (2B), —a pump (103), —a fluidic circuit (104) connecting the first connector (101), the second connector (102) and the pump (103), wherein the first connector (101) comprises a crankpin (1011) in rotating engagement within a body (1010), said crankpin comprising a unique axial port (1011A) intended to fluidically couple to the first container, a radial port (1011B) fluidically connected to said axial port (1011A), and at least one channel (1011C) arranged therein so as to cooperate with the radial ports of the body (1010) to selectively connect the axial port (1011A) of the first connector with at least one channel portion of the fluidic circuit (104) depending on the angular position of the crankpin (1011) with respect to the body (1010), a power unit (200) releasably coupled to the fluidic unit (100), comprising: —a power mechanism (203) for actuating the pump, —transmission means connected between an actuator and the crankpin (1011) for rotating the first container (2A).