公开(公告)号：US20080086155A1

公开(公告)日：2008-04-10

申请号：US11951188

申请日：2007-12-05

Applicant: Chris ROTHE ,  Richard EWERS ,  Cang LAM ,  Vahid SAADAT ,  Kenneth MICHLITSCH

Inventor： Chris ROTHE ,  Richard EWERS ,  Cang LAM ,  Vahid SAADAT ,  Kenneth MICHLITSCH

IPC: A61B17/08 ,  A61D1/00

CPC classification number: A61B1/0014 ,  A61B17/0401 ,  A61B17/06066 ,  A61B17/29 ,  A61B17/295 ,  A61B2017/00867 ,  A61B2017/00876 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/06076 ,  A61B2017/3488 ,  A61B2090/037

Abstract: Apparatus and methods for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to a longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body.

Abstract translation: 本文描述了用于操纵和固定组织的装置和方法。 在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，位于 所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。 稳定构件可以适于相对于细长管状构件的纵向轴线成角度。 此外，一个或所有关节运动控制和功能可以集成到通过刚性或柔性管状体连接到组织操作组件的单个手柄组件中。

公开(公告)号：US20070142849A1

公开(公告)日：2007-06-21

申请号：US11303521

申请日：2005-12-16

Applicant: Richard Ewers ,  Arvin Chang ,  John Cox

Inventor： Richard Ewers ,  Arvin Chang ,  John Cox

IPC: A61B17/08

CPC classification number: A61B17/30 ,  A61B17/22031 ,  A61B17/29 ,  A61B2017/00349 ,  A61B2017/3488 ,  A61B2090/034 ,  A61B2090/062 ,  A61B2090/0811 ,  A61B2090/3614

Abstract: Helical tissue manipulation instruments and methods of their use are described herein. A helical tissue engager is adapted to reversibly engage tissue and is positioned upon a flexible shaft which is advanceable through a rigidizable endoscopic assembly. The flexible shaft defines a marked section proximal to the tissue engager which can include any number of markings, designs, patterns, projections, textures, etc., which acts to provide a visual indication to the user as to the translational movement, rotation, direction of rotation, etc., of the tissue engager and the shaft. An optional guidewire can be advanced through the tissue engager. Additionally, the tissue engager and shaft can be advanced through an optional tubular sheath which may be used for dilating tissue openings prior to passage of the helical engager through the tissue opening.

Abstract translation: 本文描述了螺旋组织操作仪器及其使用方法。 螺旋组织接合器适于可逆地接合组织并且被定位在柔性轴上，柔性轴可前进通过可硬化的内窥镜组件。 柔性轴限定靠近组织接合器的标记部分，其可以包括任何数量的标记，设计，图案，投影，纹理等，其用于向使用者提供关于平移运动，旋转，方向 旋转等组织接合器和轴。 可选的导丝可以穿过组织夹持器。 此外，组织收集器和轴可以通过可选的管状护套前进，可选的管状护套可用于在螺旋装置通过组织开口之前扩张组织开口。

公开(公告)号：US20060189845A1

公开(公告)日：2006-08-24

申请号：US11365088

申请日：2006-02-28

Applicant: Tracy Maahs ,  Richard Ewers ,  Arvin Chang ,  Chris Rothe ,  Eugene Chen ,  Marvin Elmer ,  Gilbert Madrid ,  Kabir Gambhir

Inventor： Tracy Maahs ,  Richard Ewers ,  Arvin Chang ,  Chris Rothe ,  Eugene Chen ,  Marvin Elmer ,  Gilbert Madrid ,  Kabir Gambhir

IPC: A61B1/00

CPC classification number: A61B1/00179 ,  A61B1/0008 ,  A61B1/00183 ,  A61B1/0051 ,  A61B1/018 ,  A61B1/04

Abstract: Methods and apparatus for off-axis visualization are described herein. An endoluminal tissue manipulation assembly is disclosed which provides for a stable endoluminal platform and which also provides for effective triangulation of tools. Such an apparatus may comprise an optionally shape-lockable elongate body defining a longitudinal axis and adapted for endoluminal advancement in a patient body, at least one articulatable visualization lumen disposed near or at a distal region of the elongate body, the at least one articulating visualization lumen being adapted to articulate off-axis relative to a longitudinal axis of the elongate body, and at least one articulatable tool arm member disposed near or at the distal region of the elongate body, the at least one articulatable tool arm member being adapted to articulate off-axis and manipulate a tissue region of interest.

Abstract translation: 本文描述了用于离轴可视化的方法和装置。 公开了一种腔内组织操作组件，其提供稳定的内腔平台，并且还提供工具的有效三角测量。 这种装置可以包括限定纵向轴线并且适于在患者体内进行腔内前进的可选形状可锁定细长体，至少一个可伸长的可视腔，其设置在细长体的远端区域附近或位于该远端区域处，该至少一个铰接可视化 内腔适于相对于细长主体的纵向轴线偏轴关节，以及设置在细长主体的远侧区域附近或其附近的至少一个可铰接工具臂构件，所述至少一个可铰接工具臂构件适于铰接 离轴并且操纵感兴趣的组织区域。

公开(公告)号：US20060183975A1

公开(公告)日：2006-08-17

申请号：US11400580

申请日：2006-04-07

Applicant: Vahid Saadat ,  Chris Rothe ,  Richard Ewers ,  Gilbert Madrid

Inventor： Vahid Saadat ,  Chris Rothe ,  Richard Ewers ,  Gilbert Madrid

IPC: A61B1/00

CPC classification number: A61B1/0051 ,  A61B1/0008 ,  A61B1/00179 ,  A61B1/00183 ,  A61B1/018 ,  A61B1/04 ,  A61B17/29

Abstract: Methods and apparatus for performing endoluminal procedures are described herein. An endoluminal tissue manipulation assembly is disclosed which provides for a stable endoluminal platform and which also provides for effective triangulation of tools. Such an apparatus may comprise an optionally shape-lockable elongate body defining a longitudinal axis and adapted for endoluminal advancement in a patient body, at least one articulatable visualization lumen disposed near or at a distal region of the elongate body, the at least one articulating visualization lumen being adapted to articulate off-axis relative to a longitudinal axis of the elongate body, and at least one articulatable tool arm member disposed near or at the distal region of the elongate body, the at least one articulatable tool arm member being adapted to articulate off-axis and manipulate a tissue region of interest.

Abstract translation: 本文描述了用于进行腔内手术的方法和装置。 公开了一种腔内组织操作组件，其提供稳定的内腔平台，并且还提供工具的有效三角测量。 这种装置可以包括限定纵向轴线并且适于在患者体内进行腔内前进的可选形状可锁定细长体，至少一个可伸长的可视腔，其设置在细长体的远端区域附近或位于该远端区域处，该至少一个铰接可视化 内腔适于相对于细长主体的纵向轴线偏轴关节，以及设置在细长主体的远侧区域附近或其附近的至少一个可铰接工具臂构件，所述至少一个可铰接工具臂构件适于铰接 离轴并且操纵感兴趣的组织区域。

公开(公告)号：US20060036267A1

公开(公告)日：2006-02-16

申请号：US10916768

申请日：2004-08-11

Applicant: Vahid Saadat ,  Richard Ewers ,  Ruey-Feng Peh

Inventor： Vahid Saadat ,  Richard Ewers ,  Ruey-Feng Peh

IPC: A61B17/08

CPC classification number: A61B17/1114 ,  A61B17/11 ,  A61B2017/00349 ,  A61B2017/00876 ,  A61B2017/0409 ,  A61B2017/1103 ,  A61B2017/1117

Abstract: Methods and apparatus for performing malabsorptive bypass procedures within a patient's gastrointestinal lumen are described comprising, for example, gastroenterostomy procedures that are preferably performed in an endoscopic or laparoscopic fashion. Anastomosis between the patient's stomach and intestine allows food to bypass at least a portion of the patient's stomach and/or intestine, thereby providing a malabsorptive region. The malabsorptive procedure may be accompanied by additional procedures, for example, pyloric occlusion, pyloroplasty, gastroplasty, gastric tissue destruction and/or intestinal pleating.

Abstract translation: 描述了在患者的胃肠腔内进行吸收不良手术的方法和装置，其包括例如胃肠造口术程序，其优选以内窥镜或腹腔镜方式进行。 患者胃和肠之间的吻合允许食物绕过患者的胃和/或肠的至少一部分，从而提供吸收不良的区域。 吸收不良的程序可伴随其他方法，例如幽门闭塞，成形术，胃成形术，胃组织破坏和/或肠打褶。

公开(公告)号：US20060020274A1

公开(公告)日：2006-01-26

申请号：US10898684

申请日：2004-07-23

Applicant: Richard Ewers ,  Cang Lam ,  Vahid Saadat

Inventor： Richard Ewers ,  Cang Lam ,  Vahid Saadat

IPC: A61B17/04

CPC classification number: A61B17/29 ,  A61B17/0401 ,  A61B17/0469 ,  A61B17/0483 ,  A61B2017/00349 ,  A61B2017/2905 ,  A61B2017/2926

Abstract: A manipulatable grasping needle is described herein. A piercing and grasping assembly generally comprises a needle body, which is optionally hollow, having a piercing tip and a grasping arm positioned proximally of the tip, wherein the grasping arm is adapted to project from the needle body and releasably retain a length of suture. Alternatively, opposing jaws can form a singular piercing tip when the jaws are closed. The assembly is positioned at the distal end of an elongate member which can be rigid or flexible for advancement through an endoscopic device. The elongate member can also comprise one or more articulatable sections to enable manipulation of the assembly into various shapes to facilitate suture and tissue manipulation. Moreover, either the needle body or grasping arm can define a notch for receiving suture material. A hooking member can also be provided to facilitate suture retrieval when grasping suture.

Abstract translation: 这里描述了可操纵的把持针。 穿刺和抓握组件通常包括可选地中空的针体，其具有穿刺尖端和位于尖端近侧的抓握臂，其中抓握臂适于从针体突出并且可释放地保持一定长度的缝合线。 或者，当夹爪关闭时，相对的夹爪可以形成单个穿刺尖端。 组件定位在细长构件的远端，细长构件的远端可以是刚性的或柔性的，用于通过内窥镜装置前进。 细长构件还可以包括一个或多个可铰接部分，以使得能够将组件操纵成各种形状以便于缝合和组织操纵。 此外，针体或抓握臂可以限定用于接收缝合材料的凹口。 还可以提供钩构件以便于在抓住缝线时促进缝合线的取出。

公开(公告)号：US20050251207A1

公开(公告)日：2005-11-10

申请号：US10841411

申请日：2004-05-07

Applicant: Jesus Flores ,  Richard Ewers ,  Tracy Maahs ,  Alex Khairkhahan ,  Ruey-Feng Peh ,  Vahid Saadat

Inventor： Jesus Flores ,  Richard Ewers ,  Tracy Maahs ,  Alex Khairkhahan ,  Ruey-Feng Peh ,  Vahid Saadat

IPC: A61B17/00 ,  A61B17/04 ,  A61B17/06

CPC classification number: A61B17/0469 ,  A61B17/00234 ,  A61B17/0487 ,  A61B2017/00827 ,  A61B2017/00867 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0445 ,  A61B2017/0446 ,  A61B2017/045 ,  A61B2017/0451 ,  A61B2017/0454 ,  A61B2017/0456 ,  A61B2017/0458 ,  A61B2017/0459 ,  A61B2017/0461 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0477 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61B2017/06028 ,  A61B2017/06052 ,  A61B2017/06176 ,  Y10T24/39 ,  Y10T24/3969

Abstract: Apparatus and methods for positioning and securing anchors are disclosed herein. The anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This uni-directional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.

公开(公告)号：US20050251202A1

公开(公告)日：2005-11-10

申请号：US10955244

申请日：2004-09-30

Applicant: Richard Ewers ,  Tracy Maahs ,  Cang Lam ,  Vahid Saadat ,  Chris Rothe

Inventor： Richard Ewers ,  Tracy Maahs ,  Cang Lam ,  Vahid Saadat ,  Chris Rothe

IPC: A61B17/00 ,  A61B17/04 ,  A61B17/06 ,  A61B17/064 ,  A61B17/08 ,  A61B17/10 ,  A61B17/28 ,  A61B17/34

CPC classification number: A61B17/0401 ,  A61B17/0469 ,  A61B17/0487 ,  A61B17/06066 ,  A61B17/064 ,  A61B17/08 ,  A61B17/10 ,  A61B17/29 ,  A61B2017/00867 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0445 ,  A61B2017/0446 ,  A61B2017/045 ,  A61B2017/0451 ,  A61B2017/0454 ,  A61B2017/0456 ,  A61B2017/0458 ,  A61B2017/0459 ,  A61B2017/0461 ,  A61B2017/0462 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/081 ,  A61B2017/3488

Abstract: Interlocking tissue anchor apparatus and methods are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. Anchor assemblies can be delivered via the tissue manipulation assembly into or through the tissue. The anchors can incorporate various temporary interlocking features or spacing elements between one another to ensure that an anchor is not prematurely ejected from the needle assembly. This allows the anchor assembly to be advanced distally as well as withdrawn proximally within a deployment sheath while avoiding inadvertently ejecting an anchor.

Abstract translation: 本文描述了联锁组织锚装置和方法。 在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，组织稳定构件 所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。 锚固组件可以经由组织操纵组件输送到组织或穿过组织。 锚固件可以在彼此之间结合各种临时互锁特征或间隔元件，以确保锚不会从针组件过早地弹出。 这允许锚固组件在部署护套内远端地向远侧推进，同时避免无意中弹出锚固件。

公开(公告)号：US20050251160A1

公开(公告)日：2005-11-10

申请号：US10954666

申请日：2004-09-29

Applicant: Vahid Saadat ,  Richard Ewers ,  Cang Lam ,  Robert Vaughan ,  Chris Rothe ,  Kenneth Michlitsch

Inventor： Vahid Saadat ,  Richard Ewers ,  Cang Lam ,  Robert Vaughan ,  Chris Rothe ,  Kenneth Michlitsch

IPC: A61B17/00 ,  A61B17/04 ,  A61B17/06 ,  A61B17/064 ,  A61B17/08 ,  A61B17/10 ,  A61B17/28 ,  A61B17/34

CPC classification number: A61F5/0086 ,  A61B17/0401 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0483 ,  A61B17/0487 ,  A61B17/06 ,  A61B17/06066 ,  A61B17/064 ,  A61B17/08 ,  A61B17/10 ,  A61B17/12013 ,  A61B17/1285 ,  A61B17/29 ,  A61B2017/00867 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0445 ,  A61B2017/0446 ,  A61B2017/045 ,  A61B2017/0451 ,  A61B2017/0454 ,  A61B2017/0456 ,  A61B2017/0458 ,  A61B2017/0459 ,  A61B2017/0461 ,  A61B2017/0462 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/081 ,  A61B2017/3488

Abstract: Apparatus for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to a longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body.

Abstract translation: 本文描述了用于操纵和固定组织的装置。 在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，组织稳定构件 所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。 稳定构件可以适于相对于细长管状构件的纵向轴线成角度。 此外，一个或所有关节运动控制和功能可以集成到通过刚性或柔性管状体连接到组织操作组件的单个手柄组件中。

公开(公告)号：US20050137456A1

公开(公告)日：2005-06-23

申请号：US10888531

申请日：2004-07-08

Applicant: Vahid Saadat ,  Richard Ewers ,  Eugene Chen

Inventor： Vahid Saadat ,  Richard Ewers ,  Eugene Chen

IPC: A61B1/005 ,  A61B1/008 ,  A61B1/01 ,  A61B1/31 ,  A61B1/32 ,  A61B1/00

CPC classification number: A61B1/0052 ,  A61B1/00078 ,  A61B1/0008 ,  A61B1/00082 ,  A61B1/00105 ,  A61B1/00135 ,  A61B1/00154 ,  A61B1/0055 ,  A61B1/0057 ,  A61B1/0058 ,  A61B1/31 ,  A61B1/32

Abstract: Apparatus and methods are provided for placing and advancing a diagnostic or therapeutic instrument in a hollow body organ of a tortuous or unsupported anatomy, comprising a handle, an overtube, a distal region having an atraumatic tip. The overtube may be removable from the handle, and have a longitudinal axis disposed at an angle relative to the handle. The overtube may be selectively stiffened to reduce distension of the organ caused by advancement of the diagnostic or therapeutic instrument. The distal region permits passive steering of the overtube caused by deflection of the diagnostic or therapeutic instrument while the atraumatic tip prevents the wall of the organ from becoming caught or pinched during manipulation of the diagnostic or therapeutic instrument.