公开(公告)号：USD829896S1

公开(公告)日：2018-10-02

申请号：US29539571

申请日：2015-09-15

Applicant: Dr. Py Institute LLC

Designer： Daniel Py

公开(公告)号：US20170203868A1

公开(公告)日：2017-07-20

申请号：US15410740

申请日：2017-01-19

Applicant: Dr. Py Institute, LLC

Inventor： Daniel Py ,  Julian V. Chan

IPC: B65B55/06 ,  B65B61/18 ,  B65B3/02 ,  B65B3/04 ,  B29C69/02 ,  A61J1/10 ,  B65D75/54 ,  A61J1/14 ,  B65B7/02 ,  B65B51/02 ,  B65B61/06

CPC classification number: B65B55/06 ,  A61J1/10 ,  A61J1/1475 ,  B29C69/00 ,  B29C69/001 ,  B29C69/02 ,  B29K2021/003 ,  B29L2031/7128 ,  B31B70/844 ,  B65B3/022 ,  B65B3/04 ,  B65B7/02 ,  B65B51/02 ,  B65B61/06 ,  B65B61/186 ,  B65D75/54 ,  B65D75/5883 ,  B65D81/3266 ,  B65D2575/586

Abstract: A sealed, empty pouch, wherein the interior of the pouch is particle and pyrogen free, is made by (i) molding a tubular film including an inner surface and an outer surface, and blowing or otherwise directing micro-filtered air and/or other gas through the tubular film during molding; (ii) flattening the molded tubular film; (iii) sealing the flattened tubular film at spaced locations, cutting the sealed film at the spaced locations, and forming a plurality of empty pouches; (iv) over-molding a fitment to the outer surface of each of a plurality of empty pouches and forming a fluid-tight seal between the fitment and the interior of the pouch; and (v) preventing the collection of particles on the inner surface of each pouch, and the exposure of each such inner surface to an ambient atmosphere throughout steps (i) through (iv).

公开(公告)号：US20170203860A1

公开(公告)日：2017-07-20

申请号：US15410758

申请日：2017-01-19

Applicant: Dr. Py Institute LLC

Inventor： Daniel Py ,  Debashis Sahoo ,  Julian V. Chan

IPC: B65B3/00 ,  A61J1/20 ,  B65B3/30 ,  B65B3/12 ,  B65B3/36

CPC classification number: B65B3/003 ,  A61J1/2048 ,  A61J3/002 ,  A61J2205/10 ,  A61J2205/60 ,  A61M39/10 ,  B65B3/12 ,  B65B3/28 ,  B65B3/30 ,  B65B3/36 ,  B65B55/08

Abstract: Apparatuses and methods for controlling transfer of substances to a formulation container to provide a predetermined formulation. A controller may utilize one or more of a flow time, flow rate or a volume of transfer of substance. Barcoded and RFID-containing components may be used to determine what connection or disconnection has been made, and/or time thereof. Process compliance may compare measured or determined flow or connection time, flow rate and/or the transfer volume to a predetermined time, flow rate and/or volume, and adjust one or more of the time, flow rate and/or the volume of the transfer. An optional holder or cradle is configured to receive therein a fluid transfer connector formed by the connection of first and second connector portions, each in fluid communication with a flow conduit or channel that delivers substance to or receives substance from its respective connector portion, only if the connector portions are properly connected together. One or more sensors may be used to determine identification information of the connector and/or flow rates of substance through the connector.

公开(公告)号：US09668914B2

公开(公告)日：2017-06-06

申请号：US14313027

申请日：2014-06-24

Applicant: Dr. Py Institute LLC

Inventor： Daniel Py ,  Norbert M Assion ,  Julian V Chan ,  Joseph M Ting

IPC: A61F9/00 ,  B05B11/00 ,  B65D81/24 ,  B65B3/00

CPC classification number: A61F9/0008 ,  B05B11/00412 ,  B05B11/0054 ,  B05B11/0072 ,  B05B11/0097 ,  B05B11/3092 ,  B05B11/3094 ,  B65B3/003 ,  B65D81/245 ,  Y10T29/49826

Abstract: An ophthalmic dispenser and method of filling and dispensing fluid stored therein. The dispenser includes a rigid housing defining a fluid-receiving chamber, a flexible bladder receivable within the fluid-receiving chamber, a pump coupled in fluid communication with the fluid-receiving chamber, and a nozzle having a valve defining an annular, axially-extending valve seat, an outlet aperture coupled in fluid communication between the valve seat and the pump, and a flexible valve cover extending about the valve seat and forming an annular, axially-extending interface therebetween. The valve interface is connectable in fluid communication with the outlet aperture, and at least part of the valve cover is movable between (i) a normally closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to pumped fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. The rigid housing is mountable within a cartridge which, in turn, is mountable within a dispenser housing including an eyelid depressor and a trigger for simultaneously actuating the eyelid depressor and pump.

公开(公告)号：US20160089502A1

公开(公告)日：2016-03-31

申请号：US14963170

申请日：2015-12-08

Applicant: Dr. Py Institute LLC

Inventor： Daniel Py

IPC: A61M5/315

CPC classification number: A61M5/31593 ,  A61J7/0053 ,  A61M5/1782 ,  A61M5/204 ,  A61M2005/3126 ,  A61M2005/3128 ,  B05B9/0426 ,  B05B11/00416 ,  B05B11/007 ,  B05B11/0072 ,  B05B11/3015 ,  B05B11/3028 ,  B05B11/3064 ,  B05B11/3077 ,  B65D83/7535 ,  G01F11/02 ,  G01F11/025 ,  G01F11/027 ,  G01F11/028

Abstract: A multiple dose syringe has a first valve defining a first valve opening pressure and a second valve defining a second valve opening pressure. A storage chamber in fluid communication with the second valve stores multiple doses of a substance therein and includes an outlet for dispensing multiple doses of the stored substance therethrough. A compression surface is movable between first and second positions and defines a compression chamber between the compression surface and the first valve. Movement of the compression surface in a direction from the first position toward the second position dispenses substance in the compression chamber through the first valve and out of the syringe. Movement of the compression surface in a direction from the second position toward the first position causes substance to flow from the storage chamber through the second valve and into the compression chamber.

Abstract translation: 多剂量注射器具有限定第一阀开启压力的第一阀和限定第二阀开启压力的第二阀。 与第二阀流体连通的储存室在其中存储多种剂量的物质，并且包括用于通过其分配多剂量的储存物质的出口。 压缩表面可在第一和第二位置之间移动，并且在压缩表面和第一阀之间限定压缩室。 压缩表面在从第一位置朝向第二位置的方向上的运动通过第一阀和注射器分配压缩室中的物质。 压缩表面在从第二位置朝向第一位置的方向上的移动使得物质从存储室通过第二阀流入压缩室。

公开(公告)号：US20150321780A1

公开(公告)日：2015-11-12

申请号：US14708196

申请日：2015-05-09

Applicant: Dr. Py Institute LLC

Inventor： Daniel Py

IPC: B65B39/00 ,  B65B55/24 ,  B65B3/04

CPC classification number: B65B43/54 ,  B65B3/003 ,  B65B3/04 ,  B65B39/001 ,  B65B39/004 ,  B65B39/12 ,  B65B51/02 ,  B65B51/10 ,  B65B55/24

Abstract: An apparatus for filling a device having a penetrable septum and a sealed chamber. The apparatus includes a filling member engageable with the penetrable septum to penetrate the septum, port(s), and a closure. The closure and filling member are movable between (i) a first position wherein the closure closes the port(s), and (ii) a second position opening the port(s). The filling member and/or septum is movable relative to the other between (i) a first position wherein the filling member is spaced from the septum, and (ii) a second position wherein the filling member is penetrated through the septum and in communication with the sealed chamber. A locking device is movable between (i) a locked position locking the closure and/or filling member in the first position, and (ii) an unlocked position allowing movement of the closure and/or filling member relative to the other and into the second position.

Abstract translation: 一种用于填充具有可穿透隔膜的装置和密封室的装置。 该装置包括可与可穿透的隔膜接合以便穿透隔膜，端口和封闭件的填充构件。 闭合和填充构件可在（i）第一位置和第二位置之间移动，第一位置，其中闭合件关闭端口，和（ii）打开端口的第二位置。 填充构件和/或隔膜可以在（i）第一位置和第二位置之间相对于另一个移动，其中填充构件与隔膜间隔开，以及（ii）第二位置，其中填充构件穿过隔膜并与 密封室。 锁定装置可以在（i）将封闭件和/或填充构件锁定在第一位置的锁定位置之间移动，以及（ii）允许封闭件和/或填充构件相对于另一个移动并进入第二位置的解锁位置 位置。

公开(公告)号：US20140371689A1

公开(公告)日：2014-12-18

申请号：US14313027

申请日：2014-06-24

Applicant: Dr. Py Institute LLC

Inventor： Daniel Py ,  Norbert M Assion ,  Julian V Chan ,  Joseph M Ting

IPC: A61F9/00 ,  B65B3/00

CPC classification number: A61F9/0008 ,  B05B11/00412 ,  B05B11/0054 ,  B05B11/0072 ,  B05B11/0097 ,  B05B11/3092 ,  B05B11/3094 ,  B65B3/003 ,  B65D81/245 ,  Y10T29/49826

Abstract: An ophthalmic dispenser and method of filling and dispensing fluid stored therein. The dispenser includes a rigid housing defining a fluid-receiving chamber, a flexible bladder receivable within the fluid-receiving chamber, a pump coupled in fluid communication with the fluid-receiving chamber, and a nozzle having a valve defining an annular, axially-extending valve seat, an outlet aperture coupled in fluid communication between the valve seat and the pump, and a flexible valve cover extending about the valve seat and forming an annular, axially-extending interface therebetween. The valve interface is connectable in fluid communication with the outlet aperture, and at least part of the valve cover is movable between (i) a normally closed position with the valve cover engaging the valve seat to close the interface and form a fluid-tight seal therebetween, and (ii) an open position with at least part of the valve cover spaced away from the valve seat in response to pumped fluid flowing through the outlet aperture at a pressure greater than a valve opening pressure to allow the passage of pressurized fluid therebetween. The rigid housing is mountable within a cartridge which, in turn, is mountable within a dispenser housing including an eyelid depressor and a trigger for simultaneously actuating the eyelid depressor and pump.

Abstract translation: 一种眼科分配器及其中储存和分配液体的方法。 分配器包括限定流体接收室的刚性壳体，可接收在流体接收室内的柔性气囊，与流体接收室流体连通的泵，以及具有限定环形轴向延伸的阀的喷嘴 阀座，连接在阀座和泵之间流体连通的出口孔，以及围绕阀座延伸并在其间形成环形的轴向延伸的接口的柔性阀盖。 阀门接口可与出口孔流体连通，并且阀盖的至少一部分可在（i）常闭位置与阀盖接合阀座之间移动以关闭接口并形成流体密封 ，并且（ii）打开位置，其中阀盖的至少一部分响应于在大于阀打开压力的压力下流过出口孔的泵送流体而与阀座间隔开，以允许加压流体在其间通过 。 刚性壳体可安装在盒中，其又可安装在分配器壳体内，该分配器壳体包括用于同时致动眼睑下压器和泵的眼睑下压器和触发器。