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公开(公告)号:US20090305337A1
公开(公告)日:2009-12-10
申请号:US12135925
申请日:2008-06-09
申请人: Shazi Iqbal , Steven M. Montgomery , Ronald Chang , Gregory Mote , Douglas B. Dority , Jeffrey S. Ross
发明人: Shazi Iqbal , Steven M. Montgomery , Ronald Chang , Gregory Mote , Douglas B. Dority , Jeffrey S. Ross
CPC分类号: G01N1/312 , G01N1/30 , G01N1/38 , G01N35/00029 , G01N35/0092 , G01N2001/386 , G01N2035/00534 , G01N2035/00792 , G01N2035/00811 , Y10T436/112499 , Y10T436/25 , Y10T436/2525
摘要: Provided is a system and method for staining of one or more samples, including providing one or more self-contained sample processing receptacles, each of the one or more self-contained sample processing receptacles configured to be inserted into an auto-staining instrument; and enabling one of one or more staining procedures appropriate for the one or more samples as a function of a choice of self-contained sample processing receptacle, each of the one or more self-contained sample processing receptacles configured to process each inserted sample of the one or more samples within the self-contained sample processing receptacle.
摘要翻译: 提供了一种用于染色一个或多个样品的系统和方法,包括提供一个或多个独立的样品处理容器,所述一个或多个独立样品处理容器中的每一个被配置为插入自动染色仪器中; 以及使得适合于所述一个或多个样品的一个或多个染色程序中的一个作为自选样品处理容器的选择的功能,所述一个或多个独立样品处理容器中的每一个被配置成处理每个插入的样品 独立样品处理容器内的一个或多个样品。
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公开(公告)号:US08431413B2
公开(公告)日:2013-04-30
申请号:US13245572
申请日:2011-09-26
申请人: Douglas B. Dority , Ronald Chang
发明人: Douglas B. Dority , Ronald Chang
IPC分类号: G01N33/53
CPC分类号: B01L3/502715 , B01L3/502 , B01L3/50273 , B01L3/502738 , B01L2200/06 , B01L2200/10 , B01L2200/16 , B01L2300/06 , B01L2300/0645 , B01L2300/0681 , B01L2300/0848 , B01L2300/0861 , B01L2300/0877 , B01L2300/123 , B01L2300/14 , B01L2400/0421 , B01L2400/0478 , B01L2400/0487 , B01L2400/0644 , G01N1/18 , G01N1/28 , G01N1/405 , Y10T436/255 , Y10T436/2575
摘要: A fluid control and processing system for controlling fluid flow among a plurality of chambers comprises a body including a fluid processing region continuously coupled fluidicly with a fluid displacement region. The fluid displacement region is depressurizable to draw fluid into the fluid displacement region and pressurizable to expel fluid from the fluid displacement region. The body includes at least one external port. The fluid processing region is fluidicly coupled with the at least one external port. The fluid displacement region is fluidicly coupled with at least one external port of the body. The body is adjustable with respect to the plurality of chambers to place the at least one external port selectively in fluidic communication with the plurality of chambers.
摘要翻译: 用于控制多个室之间的流体流动的流体控制和处理系统包括主体,其包括与流体位移区域流体连续耦合的流体处理区域。 流体位移区域是可减压的,以将流体吸入流体移动区域并且可加压以从流体位移区域排出流体。 身体至少包括一个外部端口。 流体处理区域与至少一个外部端口流体耦合。 流体位移区域与主体的至少一个外部端口流体耦合。 主体相对于多个室可调节以将至少一个外部端口选择性地与多个室流体连通。
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公开(公告)号:US08409531B2
公开(公告)日:2013-04-02
申请号:US12512926
申请日:2009-07-30
IPC分类号: B01L3/00 , G01N31/00 , G01N33/543 , B65G47/14 , B23Q7/04 , B65H3/06 , B65H3/24 , B65H3/44 , B65H1/08 , B65H3/00 , G01N1/00 , G07F9/00 , G07F11/16 , B65G59/00
CPC分类号: B01L3/527 , B01J19/0046 , B01J2219/00468 , B01J2219/005 , B01J2219/00657 , B01L3/0289 , B01L2200/0647 , B01L2200/16 , G01N2035/00574 , Y10T436/25
摘要: Embodiments of the invention provide an efficient and effective technique for storing and dispensing reagent beads. In some embodiments, an apparatus is provided for dispensing reagent beads contained in a bead storage device which includes a bead carrier having a plurality of wells; a plurality of reagent beads disposed in the wells; and a cover tape releasably attached to the bead carrier to cover the wells and retain the reagent beads in the wells. The apparatus comprises a channel in which to place the bead storage device with the bead carrier facing a support wall of the channel and the cover tape facing a stripping wall of the channel. The stripping wall includes a stripping gap disposed between a stripping edge and an opposite edge, and a dispense opening provided adjacent the opposite edge on a side of the stripping wall opposite from the stripping edge. The cover tape is insertable through the stripping gap to be pulled against the stripping edge to peel the cover tape from the bead carrier to move the wells of the bead carrier inside the channel toward the dispense opening and expose the wells individually to dispense the reagent beads.
摘要翻译: 本发明的实施方案提供了用于存储和分配试剂珠的有效和有效的技术。 在一些实施例中,提供了一种用于分配包含在珠子存储装置中的试剂珠粒的装置,其包括具有多个孔的珠粒载体; 设置在所述孔中的多个试剂珠; 以及可剥离地附接到胎圈载体以覆盖孔并将试剂珠保持在孔中的覆盖带。 该装置包括一个通道,在该通道中,珠子存放装置使胎圈承载件面向通道的支撑壁,盖带面向通道的剥离壁。 剥离壁包括设置在剥离边缘和相对边缘之间的剥离间隙,以及在剥离壁的与剥离边缘相对的一侧上邻近相对边缘设置的分配开口。 覆盖带可以通过剥离间隙被插入以被拉靠在剥离边缘上,以从胎圈载体上剥离覆盖带,以将通道内的胎圈载体的孔移动到分配开口,并单独暴露孔以分配试剂珠 。
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公开(公告)号:US20160178489A1
公开(公告)日:2016-06-23
申请号:US14642698
申请日:2015-03-09
申请人: Shazi S. Iqbal , Steven M Montgomery , Ronald Chang , Gregory E. Mote , Douglas B. Dority , Jeffrey S. Ross
发明人: Shazi S. Iqbal , Steven M Montgomery , Ronald Chang , Gregory E. Mote , Douglas B. Dority , Jeffrey S. Ross
IPC分类号: G01N1/31
CPC分类号: G01N1/312 , B01L3/502715 , B01L3/502738 , B01L9/527 , B01L2200/16 , B01L2300/0822 , B01L2400/0605 , G01N1/30 , G01N1/38 , G01N35/00029 , G01N35/0092 , G01N2001/386 , G01N2035/00534 , G01N2035/00792 , G01N2035/00811 , Y10T436/112499 , Y10T436/25 , Y10T436/2525
摘要: Provided is a system and method for staining of one or more samples, including providing one or more self-contained sample processing receptacles, each of the one or more self-contained sample processing receptacles configured to be inserted into an auto-staining instrument; and enabling one of one or more staining procedures appropriate for the one or more samples as a function of a choice of self-contained sample processing receptacle, each of the one or more self-contained sample processing receptacles configured to process each inserted sample of the one or more samples within the self-contained sample processing receptacle.
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公开(公告)号:US08765453B2
公开(公告)日:2014-07-01
申请号:US13330472
申请日:2011-12-19
申请人: Shazi S Iqbal , Steven M Montgomery , Ronald Chang , Gregory E Mote , Douglas B Dority , Jeffrey S Ross
发明人: Shazi S Iqbal , Steven M Montgomery , Ronald Chang , Gregory E Mote , Douglas B Dority , Jeffrey S Ross
CPC分类号: G01N1/312 , G01N1/30 , G01N1/38 , G01N35/00029 , G01N35/0092 , G01N2001/386 , G01N2035/00534 , G01N2035/00792 , G01N2035/00811 , Y10T436/112499 , Y10T436/25 , Y10T436/2525
摘要: Provided is a system and method for staining of one or more samples, including providing one or more self-contained sample processing receptacles, each of the one or more self-contained sample processing receptacles configured to be inserted into an auto-staining instrument; and enabling one of one or more staining procedures appropriate for the one or more samples as a function of a choice of self-contained sample processing receptacle, each of the one or more self-contained sample processing receptacles configured to process each inserted sample of the one or more samples within the self-contained sample processing receptacle.
摘要翻译: 提供了一种用于染色一个或多个样品的系统和方法,包括提供一个或多个独立的样品处理容器,所述一个或多个独立样品处理容器中的每一个被配置为插入自动染色仪器中; 以及使得适合于所述一个或多个样品的一个或多个染色程序中的一个作为自选样品处理容器的选择的功能,所述一个或多个独立样品处理容器中的每一个被配置成处理每个插入的样品 独立样品处理容器内的一个或多个样品。
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公开(公告)号:US20120321534A1
公开(公告)日:2012-12-20
申请号:US13330445
申请日:2011-12-19
申请人: Shazi Iqbal , Steven M. Montgomery , Ronald Chang , Gregory Mote , Douglas B Dority , Jeffrey S. Ross
发明人: Shazi Iqbal , Steven M. Montgomery , Ronald Chang , Gregory Mote , Douglas B Dority , Jeffrey S. Ross
IPC分类号: G01N1/31
CPC分类号: G01N1/312 , B01L3/502715 , B01L3/502738 , B01L9/527 , B01L2200/16 , B01L2300/0822 , B01L2400/0605 , G01N1/30 , G01N1/38 , G01N35/0092 , G01N2001/386 , G01N2035/00138 , G01N2035/00534 , G01N2035/00792 , G01N2035/00811 , Y10T436/112499 , Y10T436/25 , Y10T436/2525
摘要: Provided is a system and method for staining of one or more samples, including providing one or more self-contained sample processing receptacles, each of the one or more self-contained sample processing receptacles configured to be inserted into an auto-staining instrument; and enabling one of one or more staining procedures appropriate for the one or more samples as a function of a choice of self-contained sample processing receptacle, each of the one or more self-contained sample processing receptacles configured to process each inserted sample of the one or more samples within the self-contained sample processing receptacle.
摘要翻译: 提供了一种用于染色一个或多个样品的系统和方法,包括提供一个或多个独立的样品处理容器,所述一个或多个独立样品处理容器中的每一个被配置为插入自动染色仪器中; 以及使得适合于所述一个或多个样品的一个或多个染色程序中的一个作为自选样品处理容器的选择的功能,所述一个或多个独立样品处理容器中的每一个被配置成处理每个插入的样品 独立样品处理容器内的一个或多个样品。
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公开(公告)号:US08293064B2
公开(公告)日:2012-10-23
申请号:US10379004
申请日:2003-03-03
申请人: Ronald Chang , Douglas B. Dority
发明人: Ronald Chang , Douglas B. Dority
IPC分类号: B29C65/40
CPC分类号: B01L3/508 , B01J19/0093 , B01J2219/00804 , B01J2219/0081 , B01J2219/00873 , B01J2219/0097 , B01L7/52 , B01L2300/042 , B01L2300/0809 , B01L2300/0858 , B01L2300/168 , B01L2300/1805 , F28D2021/0077 , F28F3/12 , F28F21/04 , F28F2280/10 , G01N21/0303 , G01N21/0332 , G01N2035/00326
摘要: A reaction vessel having a reaction chamber for holding a sample is fabricated by producing a housing having a rigid frame defining the minor walls of the chamber. The housing also defines a port for introducing fluid into the chamber. At least one sheet or film is attached to the rigid frame to form at least one major wall of the chamber. In preferred embodiments, two sheets or films are attached to opposite sides of the rigid frame to form two opposing major walls of the chamber, the major walls being connected to each other by the minor walls.
摘要翻译: 具有用于保持样品的反应室的反应容器通过制造具有限定室的小壁的刚性框架的壳体来制造。 壳体还限定了用于将流体引入腔室的端口。 至少一个片或薄膜连接到刚性框架以形成腔室的至少一个主壁。 在优选实施例中,两个片或膜连接到刚性框架的相对侧面以形成腔室的两个相对的主壁,主壁通过次壁彼此连接。
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公开(公告)号:US20090308886A1
公开(公告)日:2009-12-17
申请号:US12512833
申请日:2009-07-30
CPC分类号: B01L3/527 , B01J19/0046 , B01J2219/00468 , B01J2219/005 , B01J2219/00657 , B01L3/0289 , B01L2200/0647 , B01L2200/16 , G01N2035/00574 , Y10T436/25
摘要: Embodiments of the invention provide an efficient and effective technique for storing and dispensing reagent beads. In some embodiments, an apparatus is provided for dispensing reagent beads contained in a bead storage device which includes a bead carrier having a plurality of wells; a plurality of reagent beads disposed in the wells; and a cover tape releasably attached to the bead carrier to cover the wells and retain the reagent beads in the wells. The apparatus comprises a channel in which to place the bead storage device with the bead carrier facing a support wall of the channel and the cover tape facing a stripping wall of the channel. The stripping wall includes a stripping gap disposed between a stripping edge and an opposite edge, and a dispense opening provided adjacent the opposite edge on a side of the stripping wall opposite from the stripping edge. The cover tape is insertable through the stripping gap to be pulled against the stripping edge to peel the cover tape from the bead carrier to move the wells of the bead carrier inside the channel toward the dispense opening and expose the wells individually to dispense the reagent beads.
摘要翻译: 本发明的实施方案提供了用于存储和分配试剂珠的有效和有效的技术。 在一些实施例中,提供了一种用于分配包含在珠子存储装置中的试剂珠粒的装置,其包括具有多个孔的珠粒载体; 设置在孔中的多个试剂珠; 以及可剥离地附接到胎圈载体以覆盖孔并将试剂珠保持在孔中的覆盖带。 该装置包括一个通道,在该通道中,珠子存放装置使胎圈承载件面向通道的支撑壁,盖带面向通道的剥离壁。 剥离壁包括设置在剥离边缘和相对边缘之间的剥离间隙,以及在剥离壁的与剥离边缘相对的一侧上邻近相对边缘设置的分配开口。 覆盖带可以通过剥离间隙被插入以被拉靠在剥离边缘上,以从胎圈载体上剥离覆盖带,以将通道内的胎圈载体的孔移动到分配开口,并单独暴露孔以分配试剂珠 。
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公开(公告)号:US08409530B2
公开(公告)日:2013-04-02
申请号:US12512833
申请日:2009-07-30
CPC分类号: B01L3/527 , B01J19/0046 , B01J2219/00468 , B01J2219/005 , B01J2219/00657 , B01L3/0289 , B01L2200/0647 , B01L2200/16 , G01N2035/00574 , Y10T436/25
摘要: Embodiments of the invention provide an efficient and effective technique for storing and dispensing reagent beads. In some embodiments, an apparatus is provided for dispensing reagent beads contained in a bead storage device which includes a bead carrier having a plurality of wells; a plurality of reagent beads disposed in the wells; and a cover tape releasably attached to the bead carrier to cover the wells and retain the reagent beads in the wells. The apparatus comprises a channel in which to place the bead storage device with the bead carrier facing a support wall of the channel and the cover tape facing a stripping wall of the channel. The stripping wall includes a stripping gap disposed between a stripping edge and an opposite edge, and a dispense opening provided adjacent the opposite edge on a side of the stripping wall opposite from the stripping edge. The cover tape is insertable through the stripping gap to be pulled against the stripping edge to peel the cover tape from the bead carrier to move the wells of the bead carrier inside the channel toward the dispense opening and expose the wells individually to dispense the reagent beads.
摘要翻译: 本发明的实施方案提供了用于存储和分配试剂珠的有效和有效的技术。 在一些实施例中,提供了一种用于分配包含在珠子存储装置中的试剂珠粒的装置,其包括具有多个孔的珠粒载体; 设置在孔中的多个试剂珠; 以及可剥离地附接到胎圈载体以覆盖孔并将试剂珠保持在孔中的覆盖带。 该装置包括一个通道,在该通道中,珠子存放装置使胎圈承载件面向通道的支撑壁,盖带面向通道的剥离壁。 剥离壁包括设置在剥离边缘和相对边缘之间的剥离间隙,以及在剥离壁的与剥离边缘相对的一侧上邻近相对边缘设置的分配开口。 覆盖带可以通过剥离间隙被插入以被拉靠在剥离边缘上,以从胎圈载体上剥离覆盖带,以将通道内的胎圈载体的孔移动到分配开口,并单独暴露孔以分配试剂珠 。
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公开(公告)号:US20120329140A1
公开(公告)日:2012-12-27
申请号:US13330472
申请日:2011-12-19
申请人: Shazi Iqbal , Steven M. Montgomery , Ronald Chang , Gregory Mote , Douglas B. Dority , Jeffrey S. Ross
发明人: Shazi Iqbal , Steven M. Montgomery , Ronald Chang , Gregory Mote , Douglas B. Dority , Jeffrey S. Ross
CPC分类号: G01N1/312 , G01N1/30 , G01N1/38 , G01N35/00029 , G01N35/0092 , G01N2001/386 , G01N2035/00534 , G01N2035/00792 , G01N2035/00811 , Y10T436/112499 , Y10T436/25 , Y10T436/2525
摘要: Provided is a system and method for staining of one or more samples, including providing one or more self-contained sample processing receptacles, each of the one or more self-contained sample processing receptacles configured to be inserted into an auto-staining instrument; and enabling one of one or more staining procedures appropriate for the one or more samples as a function of a choice of self-contained sample processing receptacle, each of the one or more self-contained sample processing receptacles configured to process each inserted sample of the one or more samples within the self-contained sample processing receptacle.
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