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    METHOD AND APPARATUS FOR GASTROINTESTINAL TRACT ABLATION FOR TREATMENT OF OBESITY
    51.
    发明申请
    METHOD AND APPARATUS FOR GASTROINTESTINAL TRACT ABLATION FOR TREATMENT OF OBESITY 有权
    用于治疗肥胖的胃肠道牵引治疗的方法和装置

    公开(公告)号：US20080275445A1

    公开(公告)日：2008-11-06

    申请号：US12114628

    申请日：2008-05-02

    Applicant: Douglas Kelly ,  David S. Utley ,  Robert A. Ganz ,  Michael P. Wallace ,  Nathan Every

    Inventor： Douglas Kelly ,  David S. Utley ,  Robert A. Ganz ,  Michael P. Wallace ,  Nathan Every

    IPC: A61B18/18

    CPC classification number: A61B18/04 ,  A61B18/1492 ,  A61B18/18 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/1467

    Abstract: Devices and methods for ablating tissue in the wall of various organs of the gastrointestinal tract of a patient in order to cure or ameliorate metabolic pathophysiological conditions such as obesity, insulin resistance, or type 2 diabetes mellitus are provided. Ablational treatment of target areas may be fractional or partial, rendering a post-treatment portion of target tissue ablated and another portion that is substantially intact. Fractional ablation is achieved by controlling the delivery of ablational energy across the surface area being treated, and controlling the depth of energy penetration into tissue. Surface area control of energy delivery may controlled by the spatial pattern of distributed ablation elements or by the selective activation of a subset of a dense pattern of ablation elements. Embodiments of the device include an ablational electrode array that spans 360 degrees and an array that spans an arc of less than 360 degrees.

    Abstract translation: 提供了用于消除患者胃肠道的各种器官的壁中的组织以便治愈或改善代谢病理生理条件如肥胖，胰岛素抵抗或2型糖尿病的装置和方法。 目标区域的消融治疗可能是部分或部分，使目标组织的后处理部分消融，另一部分基本上完好无损。 通过控制穿过所治疗的表面区域的消融能量的传递并控制能量渗入组织的深度来实现分数消融。 能量输送的表面积控制可以由分布式消融元件的空间模式控制，或者通过选择性地激活消融元件的密集图案的子集。 该装置的实施例包括跨越360度的消融电极阵列和跨越小于360度的弧的阵列。

    SURGICAL APPARATUS WITH EXPANDABLE STRUCTURE AND ELECTRODE FOR TREATING BODY TISSUE
    55.
    发明申请
    SURGICAL APPARATUS WITH EXPANDABLE STRUCTURE AND ELECTRODE FOR TREATING BODY TISSUE 审中-公开
    具有可扩展结构的外科手术和用于治疗身体组织的电极

    公开(公告)号：US20140135759A1

    公开(公告)日：2014-05-15

    申请号：US14158843

    申请日：2014-01-19

    Applicant: Scott West ,  David S. Utley ,  John W. Gaiser

    Inventor： Scott West ,  David S. Utley ,  John W. Gaiser

    IPC: A61B18/14 ,  A61M29/02

    CPC classification number: A61B18/1485 ,  A61B1/00154 ,  A61M16/0493 ,  A61M25/02 ,  A61M29/02 ,  A61M2025/024 ,  Y10S128/06 ,  Y10S128/26

    Abstract: Systems and methods are provided for positioning and stabilizing an external instrument during insertion of the instrument through the oral cavity (e.g., insertion of a catheter through the oral cavity and into the esophagus or cardia for treatment of gastroesophageal reflux disease (GERD)). The systems and methods provide a gripping tool for association with a bite block, capable of selectively moving between an open position in which the instrument may be inserted or removed, and a closed position in which the external instrument is held in a fixed position.

    Abstract translation: 提供了系统和方法，用于在将器械插入口腔（例如，将导管穿过口腔插入食管或贲门以治疗胃食管反流病（GERD））期间定位和稳定外部器械。 这些系统和方法提供了一种用于与咬合块相关联的夹持工具，其能够选择性地在可以插入或移除该器械的打开位置之间移动，以及将外部器械保持在固定位置的关闭位置。

    SYSTEMS AND METHODS EMPLOYING A BITE BLOCK INSERT FOR POSITIONING AND STABILIZING EXTERNAL INSTRUMENTS DEPLOYED WITHIN THE BODY
    57.
    发明申请
    SYSTEMS AND METHODS EMPLOYING A BITE BLOCK INSERT FOR POSITIONING AND STABILIZING EXTERNAL INSTRUMENTS DEPLOYED WITHIN THE BODY 有权
    系统和方法使用一个用于定位和稳定位于身体内部的外部仪器的BITE块插入

    公开(公告)号：US20130046301A1

    公开(公告)日：2013-02-21

    申请号：US13656714

    申请日：2012-10-21

    Applicant: Scott West ,  David S. Utley ,  John W. Gaiser

    Inventor： Scott West ,  David S. Utley ,  John W. Gaiser

    IPC: A61B18/14

    CPC classification number: A61B18/1485 ,  A61B1/00154 ,  A61M16/0493 ,  A61M25/02 ,  A61M29/02 ,  A61M2025/024 ,  Y10S128/06 ,  Y10S128/26

    Abstract: Systems and methods are provided for positioning and stabilizing an external instrument during insertion of the instrument through the oral cavity (e.g., insertion of a catheter through the oral cavity and into the esophagus or cardia for treatment of gastroesophageal reflux disease (GERD)). The systems and methods provide a gripping tool for association with a bite block, capable of selectively moving between an open position in which the instrument may be inserted or removed, and a closed position in which the external instrument is held in a fixed position.

    Abstract translation: 提供了系统和方法，用于在将器械插入口腔（例如，将导管穿过口腔插入食管或贲门以治疗胃食管反流病（GERD））期间定位和稳定外部器械。 这些系统和方法提供了一种用于与咬合块相关联的夹持工具，其能够选择性地在可以插入或移除该器械的打开位置之间移动，以及将外部器械保持在固定位置的关闭位置。

    Method and Apparatus for Ablation of Benign, Pre-Cancerous and Early Cancerous Lesions That Originate Within the Epithelium and are Limited to the Mucosal Layer of the Gastrointestinal Tract
    60.
    发明申请
    Method and Apparatus for Ablation of Benign, Pre-Cancerous and Early Cancerous Lesions That Originate Within the Epithelium and are Limited to the Mucosal Layer of the Gastrointestinal Tract 审中-公开
    用于消除起源于上皮内并且限于胃肠道粘膜层的良性，癌前和早期癌性病变的方法和装置

    公开(公告)号：US20090012518A1

    公开(公告)日：2009-01-08

    申请号：US12168042

    申请日：2008-07-03

    Applicant: David S. Utley ,  Michael P. Wallace

    Inventor： David S. Utley ,  Michael P. Wallace

    IPC: A61B18/14

    CPC classification number: A61B18/1492 ,  A61B18/02 ,  A61B18/18 ,  A61B2018/0016 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00482 ,  A61B2018/00642 ,  A61B2018/00702 ,  A61B2018/00779 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/044 ,  A61B2018/1467 ,  A61B2018/1497 ,  A61B2090/064 ,  A61B2218/007

    Abstract: Devices and methods are provided for ablating areas of the gastrointestinal tract affected with certain benign, pre-cancerous, or early cancerous lesions that originate within the epithelium and are limited to the mucosal layer of the gastrointestinal tract wall. Examples of such lesions include benign conditions such as cervical inlet patch (ectopic gastric mucosa in the upper esophagus), as well as pre-cancerous and cancerous conditions such as intestinal metaplasia/intra-epithelial neoplasia/early cancer of the stomach, squamous intra-epithelial neoplasia and early cancer of the esophagus, oral and pharyngeal leukoplakia, flat colonic polyps, anal intra-epithelial neoplasia (AIN), and early cancers of the anal canal. Ablation, as provided the invention, commences at the epithelial layer of the gastrointestinal wall and penetrates deeper into the gastrointestinal wall in a controlled manner to achieve a successful patient outcome, the latter of which is defined generally as eradication of the targeted lesion, and/or a change in the targeted lesion to prevent or forestall patient morbidity. Embodiments of the device include an ablational electrode array that spans 360 degrees and an array that spans an arc of less than 360 degrees.

    Abstract translation: 提供了装置和方法，用于消融受到某些良性，癌前或早期癌性病变影响的胃肠道区域，这些病变起源于上皮内，并限于胃肠道壁的粘膜层。 这种病变的实例包括诸如宫颈入口贴片（上食管中的异位胃粘膜）的良性病症，以及癌前和癌症状况如肠化生/上皮内瘤变/胃癌早期癌，鳞状内膜炎， 食道上皮性肿瘤和早期癌症，口腔和咽部白斑，扁平结肠息肉，肛门上皮内瘤变（AIN）和肛管早期癌症。 根据本发明，消融在胃肠壁的上皮层开始，并以受控的方式深入胃肠壁以实现成功的患者结果，后者通常定义为根除靶向病变，和/ 或改变目标病变以预防或预防患者发病。 该装置的实施例包括跨越360度的消融电极阵列和跨越小于360度的弧的阵列。

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