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62 条记录 (耗时 0.041 秒)

    Apparatus and method for delivering therapeutic and diagnostic agents
    51.
    发明授权
    Apparatus and method for delivering therapeutic and diagnostic agents 失效
    用于递送治疗和诊断剂的装置和方法

    公开(公告)号：US07211041B2

    公开(公告)日：2007-05-01

    申请号：US11090859

    申请日：2005-03-25

    申请人： Richard Mueller

    发明人： Richard Mueller

    IPC分类号： A61B1/00

    CPC分类号： A61B17/3207 ,  A61B17/221 ,  A61B2017/00247 ,  A61B2017/22077 ,  A61B2017/22082 ,  A61B2017/2212 ,  A61B2018/00392 ,  A61B2090/064 ,  A61M2025/0089 ,  A61M2210/125

    摘要： A drug-delivery tool and method for delivering a diagnostic or therapeutic agent to a target site within a selected body tissue, such as the myocardium of the heart, is disclosed. The drug-delivery tool generally includes an accessing device having a tissue-penetrating implement in its distal-end region, and elements for delivering a selected agent into a cavity formed by the implement. Methods of use are also described.

    摘要翻译： 公开了用于将诊断或治疗剂递送到所选择的身体组织（例如心脏心肌）内的靶位点的药物递送工具和方法。 药物递送工具通常包括在其远端区域中具有组织穿透工具的进入装置，以及用于将所选择的药剂输送到由器具形成的空腔中的元件。 还描述了使用方法。

    Spinal implant adjustment device
    53.
    发明申请
    Spinal implant adjustment device 失效
    脊柱植入物调整装置

    公开(公告)号：US20060217712A1

    公开(公告)日：2006-09-28

    申请号：US10550329

    申请日：2004-03-24

    申请人： Richard Mueller ,  Andrew Budd ,  Marc Silski

    发明人： Richard Mueller ,  Andrew Budd ,  Marc Silski

    IPC分类号： A61F2/30

    CPC分类号： A61B17/7052 ,  A61B17/7032 ,  A61F2/44 ,  A61F2/4455 ,  A61F2002/2835 ,  A61F2002/30367 ,  A61F2002/30378 ,  A61F2002/30405 ,  A61F2002/30471 ,  A61F2002/30495 ,  A61F2002/305 ,  A61F2002/30505 ,  A61F2002/30507 ,  A61F2002/30538 ,  A61F2002/30601 ,  A61F2002/30777 ,  A61F2002/30784 ,  A61F2002/30841 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2220/0091 ,  A61F2250/0006

    摘要： An adjustable spinal implant (10) is provided for use in connecting elongate members (12) as well as vertebral spacers such as corpectomy devices, intervertebral fusion devices, and other prostheses. The implant (10) may have fittings (80) on either end comprising fixed (100) or articulating (200) jaws, endplates, or other engagement structures. The implant (10) comprises a housing (40) with an internal rotor (60); an extending shaft (20); and a locking collar (70). The extending shaft (20) has an external helical groove (23) that meshes with an internal helical groove (63) on rotor (20). Length adjustment occurs by transforming axial movement of the extending shaft (20) into a rotary movement of the rotor (60) via helical engagement. The locking collar (70) comprises protrusion (73) engaging grooves (63) of rotor (60), thus providing a simple, positive locking mechanism without requiring the surgeon to apply excessive force to lock the length.

    摘要翻译： 提供可调节的脊柱植入物（10），用于连接细长构件（12）以及脊椎间隔物，例如椎体切除装置，椎间融合装置和其他假体。 植入物（10）可以在任一端上具有包括固定（100）或铰接（200）颚板，端板或其它接合结构的接头（80）。 植入物（10）包括具有内转子（60）的壳体（40）; 延伸轴（20）; 和锁定环（70）。 延伸轴（20）具有与转子（20）上的内螺旋槽（63）啮合的外螺旋槽（23）。 通过将延伸轴（20）的轴向运动通过螺旋接合转换成转子（60）的旋转运动来进行长度调节。 锁定环（70）包括突起（73）接合转子（60）的凹槽（63），从而提供简单的正向锁定机构，而不需要外科医生施加过大的力来锁定长度。

    Process for preparing alkyl tert-butyl ethers and di-n-butene from field butanes
    57.
    发明授权
    Process for preparing alkyl tert-butyl ethers and di-n-butene from field butanes 失效
    从野外丁烷制备烷基叔丁基醚和二正丁烯的方法

    公开(公告)号：US5864052A

    公开(公告)日：1999-01-26

    申请号：US899792

    申请日：1997-07-24

    申请人： Franz Nierlich ,  Paul Olbrich ,  Wilhelm Droste ,  Richard Mueller ,  Walter Toetsch

    发明人： Franz Nierlich ,  Paul Olbrich ,  Wilhelm Droste ,  Richard Mueller ,  Walter Toetsch

    IPC分类号： C07C11/02 ,  C07C41/06 ,  C07C43/04

    CPC分类号： C07C11/02 ,  C07C41/06

    摘要： The invention relates to a process for preparing di-n-butene and alkyl tertbutyl ethers in a coupled production from field butanes, which indicates (a) separating the field butanes 1 into n-butane and isobutane in the separation stage 4, (b) dehydrogenating the n-butane 5 in a dehydrogenation stage 6 to give an n-butene-containing dehydrogenation mixture 7, oligomerizing the n-butene in the oligomerization stage 10 to give an oligomer mixture 11 and separating di-n-butene 12 off from this, and (c) de-hydrogenating the isobutane 15 in the dehydrogenation stage 16 to give an isobutene-containing dehydrogenation mixture 17 and reacting the isobutene with an alkanol 20 in the etherification stage 19 to give an alkyl tert-butyl ether 21. In an advantageous embodiment, the field butanes 1, prior to entry into the separation stage 4, are subjected to hydrogenation conditions in the hydrogenation stage 2 and an isomerization stage 3 is assigned to the separation stage 4, by means of which isomerization stage the ratio of n-butane to isobutane is set in accordance with the desired ratio of alkyl tertbutyl ether to di-n-butene.

    摘要翻译： 本发明涉及一种从场丁烷偶联制备二正丁烯和烷基叔丁基醚的方法，其表明（a）在分离段4中将场丁烷1分离成正丁烷和异丁烷;（b） 在脱氢阶段6中使正丁烷5脱氢，得到含正丁烯的脱氢混合物7，使低聚反应阶段10中的正丁烯低聚，得到低聚物混合物11，并从其中分离出二 - 正丁烯12 ，和（c）脱氢阶段16中的异丁烷15脱氢，得到含异丁烯的脱氢混合物17，并使异丁烯与醚化阶段19中的链烷醇20反应，得到烷基叔丁基醚21.在 有利的实施方案中，进入分离阶段4之前的现场丁烷1在氢化阶段2中经受氢化条件，异构化阶段3分配给分离阶段4 根据所需的烷基叔丁醚与二正丁烯的比例来设定正丁烷与异丁烷的比例。

    Machine for the precision working of the tooth flanks of gear-shaped workpieces with an internally toothed tool
    58.
    发明授权
    Machine for the precision working of the tooth flanks of gear-shaped workpieces with an internally toothed tool 失效
    齿轮工件齿面精密加工的机床，内齿工具

    公开(公告)号：US5443338A

    公开(公告)日：1995-08-22

    申请号：US271512

    申请日：1994-07-07

    申请人： Manfred Huber ,  Richard Mueller ,  Anton Schaller

    发明人： Manfred Huber ,  Richard Mueller ,  Anton Schaller

    IPC分类号： B23F19/00 ,  B23F19/05 ,  B23F19/06 ,  B23F23/02 ,  B23F23/04 ,  B23F23/12 ,  B23Q1/48 ,  B23Q7/04

    CPC分类号： B23Q7/048 ,  B23F19/007 ,  B23F19/057 ,  B23F19/063 ,  B23F23/04 ,  B23F23/1231 ,  B23F23/1281 ,  B23Q1/48 ,  B23Q1/4828 ,  Y10S451/90 ,  Y10T409/100954 ,  Y10T409/105724

    摘要： A machine for the precision working of tooth flanks of a gear-shaped workpiece. The machine having an internally toothed tool, a tool head angularly adjustable about an axis directed transversely with respect to a workpiece axis for rotationally drivably receiving the tool, means for receiving the workpiece to be machined and means for accomplishing the feeding and working movements of the tool relative to the workpiece in which movable tables existing in conventional machines for receiving the workpieces are avoided with the disadvantages resulting therefrom. The machine also having a frame, a first carriage horizontally movable in an X-direction transversely with respect to a workpiece axis, on which carriage is arranged a second carriage vertically movable in a Y-direction. The tool head is received pivotally about an axis lying in the X-direction in a circular guide in the second carriage. On each side of the tool head there are provided a headstock and a tailstock for receiving the workpiece. The headstock and tailstock are movable on the machine frame in the Z-direction, namely in the direction of the workpiece axis. The headstock is drivable and the tailstock follows correspondingly.

    摘要翻译： 齿轮工件齿面精密加工的机器。 所述机器具有内齿工具，工具头可围绕相对于工件轴线横向指向的轴线成角度地调节，用于可旋转地驱动地接收工具，用于接收待加工的工件的装置和用于完成工件运动的装置 相对于工件的工具，其中避免了存在于用于接收工件的常规机器中的可移动台，由此产生的缺点。 所述机器还具有框架，第一台架可相对于工件轴线在X方向上横向移动，所述托架布置在所述Y方向上可垂直移动的第二托架。 所述工具头绕着位于所述X方向上的轴枢转地接收在所述第二滑架中的圆形引导件中。 在工具头的每一侧上设置有用于接收工件的主轴箱和尾架。 主轴箱和尾架可在机架上沿Z方向，即沿工件轴线方向移动。 头架是可驱动的，尾座相应地跟随。