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    PHOTOSENSITIVE COMPOUND, PHOTOSENSITIVE RESIN, AND PHOTOSENSITIVE COMPOSITION
    55.
    发明申请
    PHOTOSENSITIVE COMPOUND, PHOTOSENSITIVE RESIN, AND PHOTOSENSITIVE COMPOSITION 有权
    感光性化合物，感光树脂和感光性组合物

    公开(公告)号：US20150079519A1

    公开(公告)日：2015-03-19

    申请号：US14391170

    申请日：2013-02-28

    申请人： TOYO GOSEI CO., LTD.

    发明人： Toru Shibuya

    IPC分类号： G03F7/038 ,  C08F116/06 ,  C07D233/60 ,  C07D263/38 ,  C07C247/16

    CPC分类号： G03F7/012 ,  C07C233/83 ,  C07C247/16 ,  C07C247/18 ,  C07D233/60 ,  C07D233/61 ,  C07D263/38 ,  C07D263/42 ,  C07D295/14 ,  C08F116/06 ,  G03F7/008 ,  G03F7/0125 ,  G03F7/0388

    摘要： A photosensitive compound represented by formula (1) or formula (2). (Chemical formula 1) (In formula (1) and formula (2), n is an integer of 1-3; R1 is a linear or branched alkyl group having 1-6 carbon atoms or an alkylene group having 2-6 carbon atoms formed from two R1 together; R2 is —NR3R4; R3 and R4 are each independently a linear or branched alkyl group or alkenyl group having 1-6 carbon atoms, a linear or branched alkylene group having 2-6 carbon atoms formed by R3 and R4 together, or a linear or branched alkylene group or alkenylene group having 3-8 carbon atoms optionally containing an oxygen atom or nitrogen atom.)

    摘要翻译： 由式（1）或式（2）表示的光敏化合物。 （化学式1）（式（1）和式（2）中，n为1〜3的整数，R 1为碳原子数1〜6的直链或支链烷基或碳原子数2〜6的亚烷基 由两个R 1一起形成; R 2是-NR 3 R 4; R 3和R 4各自独立地是具有1-6个碳原子的直链或支链烷基或烯基，由R3和R4形成的具有2-6个碳原子的直链或支链亚烷基 一起或具有任选含有氧原子或氮原子的具有3-8个碳原子的直链或支链亚烷基或亚烯基）

    BITOPIC MUSCARINIC AGONISTS AND ANTAGONISTS AND METHODS OF SYNTHESIS AND USE THEREOF
    56.
    发明申请
    BITOPIC MUSCARINIC AGONISTS AND ANTAGONISTS AND METHODS OF SYNTHESIS AND USE THEREOF 有权
    双极肌肉激素和拮抗剂及其合成和使用方法

    公开(公告)号：US20140018366A1

    公开(公告)日：2014-01-16

    申请号：US13937350

    申请日：2013-07-09

    申请人： BARRY UNIVERSITY, INC.

    发明人： John BOULOS

    IPC分类号： C07D417/06 ,  C07D405/06 ,  C07D295/14

    CPC分类号： A61K31/452 ,  A61K31/443 ,  A61K31/4439 ,  A61K31/5375 ,  A61K45/06 ,  C07D295/104 ,  C07D295/14 ,  C07D405/06 ,  C07D417/06

    摘要： Compositions for treating a condition associated with activity of a muscarinic receptor (e.g., one or more of M1, M2, M3, M4, M5) and for anesthetizing a subject include a bitopic muscarinic antagonist or agonist. A bitopic muscarinic antagonist named JB-D4 was discovered. This bitopic ligand and its structural analogs, as well as bitopic muscarinic agonists, may be used as neuromuscular blocking agents (e.g., for use in compositions for anesthetizing a subject) and for the treatment of central nervous system disorders (e.g., Parkinson's disease, Schizophrenia, etc.), Overactive Bladder Syndrome, Chronic Obstructive Pulmonary Disease, asthma, and many other diseases associated with the activation or inhibition of M1-M5 acetylcholine receptors.

    摘要翻译： 用于治疗与毒蕈碱受体（例如，M1，M2，M3，M4，M5中的一种或多种）的活性相关的病症的组合物和用于麻醉受试者的组合物包括苦味毒蕈碱性拮抗剂或激动剂。 发现了一种名为JB-D4的苦涩毒蕈碱拮抗剂。 这种比特配位体及其结构类似物以及苦味碱激动剂可用作神经肌肉阻滞剂（例如用于麻醉受试者的组合物）和治疗中枢神经系统疾病（例如，帕金森病，精神分裂症 等），过度活动性膀胱综合征，慢性阻塞性肺疾病，哮喘和许多其他与M1-M5乙酰胆碱受体活化或抑制相关的疾病。