公开(公告)号：US11833353B2

公开(公告)日：2023-12-05

申请号：US17315160

申请日：2021-05-07

Applicant: VERITAS IP, LLC

Inventor： Andrew Miller Wilder ,  Scott Darold Hiatt ,  Steven John Barrus ,  Cliff C. Nixon

IPC: A61N1/02 ,  A61N1/36 ,  A61B5/00 ,  G06F3/01 ,  A61N1/08

CPC classification number: A61N1/36128 ,  A61B5/7217 ,  A61N1/025 ,  G06F3/015 ,  A61N2001/083

Abstract: Various embodiments of an interface control subsystem may be used between an electrode terminal and a recording terminal of a neurostimulation and neurorecording system. The interface control subsystem may operate in three modes. In a disable mode, a first transistor and a second transistor disposed between the electrode terminal and the recording terminal may operate in a cutoff region and generate a high impedance. In an active mode, the first transistor and the second transistor may operate in a saturation region and generate a low impedance. In a stimulation mode, the first transistor and the second transistor operate in a triode region and generate an impedance between the high impedance of the disable mode and the low impedance of the active mode. The interface control subsystem may further limit voltage at the recording terminal in response to a detected overvoltage condition.

公开(公告)号：US11819697B2

公开(公告)日：2023-11-21

申请号：US17159596

申请日：2021-01-27

Applicant: Medtronic, Inc.

Inventor： Todd J. Sheldon ,  Keelia M. Escalante ,  Greggory R. Herr ,  Juliana E. Pronovici ,  Vincent E. Splett

IPC: A61N1/36 ,  A61N1/365 ,  A61N1/02 ,  A61N1/375 ,  G16H40/67 ,  G16H50/30 ,  G16H20/30 ,  A61N1/372 ,  A61N1/05

CPC classification number: A61N1/36542 ,  A61N1/025 ,  A61N1/3756 ,  A61N1/37512 ,  G16H20/30 ,  G16H40/67 ,  G16H50/30 ,  A61N1/0573 ,  A61N1/37211

Abstract: A medical device includes a motion sensor configured to produce a motion signal and a control circuit configured to set sensing control parameters and sense atrial events from the motion signal during ventricular cycles according to the sensing control parameters. In some examples, the control circuit is configured to determine a feature of the motion signal for at least some ventricular cycles, determine a metric of the motion signal based on the determined features, and adjust at least one of the sensing control parameters based on the metric.

公开(公告)号：US11806538B2

公开(公告)日：2023-11-07

申请号：US17747011

申请日：2022-05-18

Applicant: BIOTRONIK SE & CO. KG

Inventor： Andrew B. Kibler ,  Lauren Kraiter ,  Larry Stotts

IPC: A61N1/02 ,  A61N1/05 ,  A61N1/36 ,  A61N1/372

CPC classification number: A61N1/37241 ,  A61N1/025 ,  A61N1/3605 ,  A61N1/0551

Abstract: A method programs an implantable medical device to configure the implantable medical device for stimulating neural tissue by at least one electrode. The method includes: performing, by the implantable medical device, an evoked compound action potential (eCAP) threshold search by stimulating the neural tissue with test stimulation pulses; determining, based on the eCAP threshold search, an eCAP threshold amplitude and a coupling factor that is indicative of a coupling between the at least one electrode and the neural tissue; and generating a first set of stimulation parameters containing at least a stimulation amplitude that is determined in dependence on the eCAP threshold amplitude and the coupling factor.

公开(公告)号：US11786743B2

公开(公告)日：2023-10-17

申请号：US16989444

申请日：2020-08-10

Applicant: Medtronic, Inc.

Inventor： Erik J. Peterson ,  Mandla Shongwe

IPC: A61N1/36 ,  A61N1/372 ,  A61N1/02

CPC classification number: A61N1/37247 ,  A61N1/025 ,  A61N1/3615 ,  A61N1/36062 ,  A61N1/36064 ,  A61N1/36067 ,  A61N1/36071 ,  A61N1/36082 ,  A61N1/36107 ,  A61N1/36146 ,  A61N1/36175 ,  A61N1/36178 ,  A61N1/36189

Abstract: A medical device stores a set of stimulation profiles, wherein each stimulation profile of the set of stimulation profiles is associated with a set of values for stimulation parameters; selects from the set of stimulation profiles, one or more active stimulation profiles; produces, by a stimulation generator, multiple electrical pulses based on the one or more active stimulation profiles; and separately controls parameter values of respective individual pulses of the multiple pulses.

公开(公告)号：US20230321435A1

公开(公告)日：2023-10-12

申请号：US17981174

申请日：2022-11-04

Applicant: Viveve, Inc.

Inventor： Deborah WILKERSON ,  Stacie BELL ,  Bruce Baldwin ALLAN

IPC: A61N1/36 ,  A61N1/40 ,  A61N5/02 ,  A61N7/02 ,  A61N1/02 ,  A61N5/04

CPC classification number: A61N1/36007 ,  A61N1/403 ,  A61N5/025 ,  A61N2007/0004 ,  A61N1/025 ,  A61N5/045 ,  A61N7/022

Abstract: Methods for treating urinary stress incontinence by non-invasively delivering energy to one or more submucosal regions of vaginal tissue to induce remodeling within the vaginal tissue are provided. In some embodiments, the energy delivery results in heating of the target tissue to a temperature that ranges from about 38° C. to about 46° C. In some embodiments, the subject methods involve cooling a mucosal epithelial layer over the vaginal tissue. In some embodiments, a reverse thermal gradient is produced as the mucosal epithelium is cooled while energy is delivered to the underlying vaginal tissue.

公开(公告)号：US11759623B2

公开(公告)日：2023-09-19

申请号：US17081114

申请日：2020-10-27

Applicant: Pacesetter, Inc.

Inventor： Dean Andersen ,  Eiji Shirai

IPC: A61B17/00 ,  A61N1/02 ,  A61N1/372 ,  A61N1/362 ,  G16H40/63 ,  A61N1/39 ,  G06F1/08 ,  G16H20/30 ,  A61N1/375

CPC classification number: A61N1/025 ,  A61N1/362 ,  A61N1/3756 ,  A61N1/37276 ,  A61N1/3956 ,  G06F1/08 ,  G16H20/30 ,  G16H40/63

Abstract: Techniques for calibrating a low frequency (LF) clock of an IMD are disclosed, wherein the IMD also includes a high frequency (HF) clock. This includes determining an average, or a surrogate thereof, of how many HF clock cycles of a HF clock signal (produced by the HF clock) occur per LF clock cycle of a predetermined number N of LF clock cycles of the LF clock signal (produced by the LF clock), wherein N is an integer that is at least 2. This also includes comparing the average or a surrogate thereof to a corresponding target value that the average or the surrogate thereof would be equal to if the frequency of the LF clock signal equaled a target frequency for the LF clock, wherein the corresponding target value need not be an integer. The LF clock is calibrated by adjusting the frequency thereof based on results of the comparing.

公开(公告)号：US20230271008A1

公开(公告)日：2023-08-31

申请号：US18068822

申请日：2022-12-20

Applicant: Universidad de Salamanca

Inventor： Enrique Alejandro López-Poveda

IPC: A61N1/36 ,  A61N1/02 ,  A61N1/05

CPC classification number: A61N1/36038 ,  A61N1/025 ,  A61N1/0541 ,  A61N1/36167 ,  A61N1/36039

Abstract: A signal processing arrangement is described for signal processing in a bilateral hearing implant system. A channel compression module develops a inhibition-adjusted band pass signal for each band pass signal using a channel-specific dynamic inhibition adjustment based on a channel-normalized medial olivocochlear reflex model that reflects bandwidth energy for a corresponding contralateral band pass signal and bandwidth energy for a selected reference contralateral band pass signal.

公开(公告)号：US20230264036A1

公开(公告)日：2023-08-24

申请号：US18305544

申请日：2023-04-24

Applicant: ZOLL Medical Corporation

Inventor： Thomas E. Kaib ,  Shane S. Volpe ,  Ernast Sevo

IPC: A61N1/39 ,  A61N1/02 ,  A61B5/00 ,  A61B5/333

CPC classification number: A61N1/3975 ,  A61B5/333 ,  A61B5/7475 ,  A61N1/025 ,  A61B5/0245

Abstract: In some examples, an ambulatory medical device is provided. The ambulatory medical device includes at least one sensor configured to acquire data descriptive of the patient, one or more processors in communication with the at least one sensor, a patient care component executable by the one or more processors, and a limited functionality component executable by the one or more processors. The patient care component is configured to perform one or more primary operations of the ambulatory medical device at least in part by accessing the data descriptive of the patient. The limited functionality component is configured to exchange information with a communication device and to not affect the one or more primary operations of the ambulatory medical device.

公开(公告)号：US20230256249A1

公开(公告)日：2023-08-17

申请号：US18139623

申请日：2023-04-26

Applicant: Boston Scientific Neuromodulation Corporation

Inventor： Michael A. Moffitt ,  Natalie A. Brill ,  Jianwen Gu ,  Juan Gabriel Hincapie Ordonez ,  Changfang Zhu ,  Hemant Bokil ,  Stephen Carcieri

IPC: A61N1/36 ,  A61N1/02 ,  A61N1/372 ,  G16H50/20

CPC classification number: A61N1/36135 ,  A61N1/025 ,  A61N1/3605 ,  A61N1/36007 ,  A61N1/36071 ,  A61N1/37247 ,  G16H50/20 ,  A61N1/36003 ,  A61N1/36132 ,  A61N1/36146 ,  G16H20/30

Abstract: An example of a system may include a processor and a memory device comprising instructions, which when executed by the processor, cause the processor to: access a patient metric of a subject; use the patient metric as an input to a machine learning algorithm, the machine learning algorithm to search a plurality of neuromodulation parameter sets and to identify a candidate neuromodulation parameter set of the plurality of neuromodulation parameter sets, the candidate neuromodulation parameter set designed to produce a non-regular waveform that varies over a time domain and a space domain; and program a neuromodulator using the candidate neuromodulation parameter set to stimulate the subject.

公开(公告)号：US11724118B2

公开(公告)日：2023-08-15

申请号：US17172859

申请日：2021-02-10

Applicant: West Affum Holdings DAC

Inventor： Joseph L. Sullivan

IPC: A61N1/39 ,  A61B5/0245 ,  A61B5/00 ,  A61B5/024 ,  A61B5/25 ,  A61B5/339 ,  A61B5/352 ,  A61B5/361 ,  A61N1/02 ,  A61N1/08 ,  A61N1/04 ,  A61B5/08 ,  A61B5/1455 ,  A61B5/11 ,  A61B5/145 ,  A61B5/02 ,  A61B5/021 ,  A61B5/026 ,  A61B5/341 ,  A61B5/364

CPC classification number: A61N1/3987 ,  A61B5/0002 ,  A61B5/0245 ,  A61B5/02438 ,  A61B5/25 ,  A61B5/339 ,  A61B5/352 ,  A61B5/361 ,  A61B5/6823 ,  A61B5/7203 ,  A61N1/025 ,  A61N1/3904 ,  A61B5/0006 ,  A61B5/021 ,  A61B5/02028 ,  A61B5/0261 ,  A61B5/02405 ,  A61B5/0816 ,  A61B5/1112 ,  A61B5/14542 ,  A61B5/14551 ,  A61B5/341 ,  A61B5/364 ,  A61B5/7275 ,  A61N1/0484 ,  A61N1/3968 ,  A61N2001/083

Abstract: In embodiments, a WCD system includes electrodes with which it senses an ECG signal of the patient. A processor may detect sequential peaks within the ECG signal, measure durations of time intervals between the peaks, including between non-sequential peaks, and identify a representative duration that best meets a plausibility criterion. The plausibility criterion may be that the representative duration is the one that occurs the most often, i.e. is the mode. Then a heart rate can be computed from a duration indicated by the representative duration and, if the heart rate meets a shock condition, the WCD system may deliver a shock to the patient. An advantage can be that the representative duration can be close to a good R-R interval measurement of a patient, notwithstanding noise in the ECG signal that is in the shape of peaks.