公开(公告)号：US20140216917A1

公开(公告)日：2014-08-07

申请号：US14246295

申请日：2014-04-07

Applicant: Paul A. Bentley ,  Michael Davenport

Inventor： Paul A. Bentley ,  Michael Davenport

IPC: B01J19/08 ,  G01N27/74

CPC classification number: B01J19/087 ,  B01F11/0082 ,  B01F13/0818 ,  B01J2219/0801 ,  B01J2219/0854 ,  B01J2219/0862 ,  B01J2219/0879 ,  B01L3/502761

Abstract: The present invention includes a magnetically susceptible polymer component, a method of making the same, and apparatuses and systems for mixing, separating or localizing a magnetically susceptible polymer compound in a reaction. The magnetically susceptible polymer component includes a polymer and a magnetically susceptible particle of a predetermined size, which yields a component having a much-improved magnetic reactivity due to the increase in magnetic material by mass percentage. The apparatuses and systems of the present invention employ controllable magnetic fields distributable in perpendicular directions in order to precisely control the orientation, position and relative motion of any magnetically susceptible components within a reaction vessel.

Abstract translation: 本发明包括磁敏感聚合物组分，其制备方法以及用于在反应中混合，分离或定位磁敏感性聚合物化合物的装置和系统。 磁敏感聚合物组分包括预定尺寸的聚合物和磁敏感颗粒，其由于磁性材料以质量百分比的增加而产生具有大大提高的磁反应性的组分。 本发明的装置和系统采用可分散在垂直方向上的可控磁场，以便精确地控制反应容器内的任何磁敏组件的取向，位置和相对运动。

公开(公告)号：US08753570B2

公开(公告)日：2014-06-17

申请号：US13001478

申请日：2009-06-26

Applicant: David Whitten ,  Yanli Tang ,  Zhijun Zhou ,  Linnea Ista ,  Motokatsu Ogawa ,  David Keller ,  Brett Andrzejewski ,  Gabriel Lopez ,  Kirk Schanze

Inventor： David Whitten ,  Yanli Tang ,  Zhijun Zhou ,  Linnea Ista ,  Motokatsu Ogawa ,  David Keller ,  Brett Andrzejewski ,  Gabriel Lopez ,  Kirk Schanze

IPC: A61L2/00 ,  A61L2/18 ,  A61L9/00 ,  C07C239/00 ,  C07C259/00

CPC classification number: C07C217/20 ,  A01N33/12 ,  A01N37/38

Abstract: Novel compounds generally referred to herein as cationic oligomeric phenylene ethynylenes (OPEs), methods of synthesizing OPEs and various uses for the OPEs are described. The compounds can be synthesized in both symmetrical (S-OPE) and non-symmetrical (N-OPE) forms. Suitable uses include sensor and biocidal applications. Reusable structures incorporating the OPEs that are able to capture and release biological species of interest are also described.

Abstract translation: 本文中通常称为阳离子低聚亚苯基乙烯基（OPE）的新型化合物，OPE的合成方法和OPE的各种用途。 这些化合物可以以对称（S-OPE）和非对称（N-OPE）的形式合成。 合适的用途包括传感器和杀菌剂应用。 还描述了结合能够捕获和释放感兴趣的生物物种的OPE的可再利用结构。

公开(公告)号：US08734816B2

公开(公告)日：2014-05-27

申请号：US13143164

申请日：2010-01-05

Applicant: Juewen Liu ,  Jeffrey C. Brinker ,  Carlee Ashley ,  Eric C. Carnes

Inventor： Juewen Liu ,  Jeffrey C. Brinker ,  Carlee Ashley ,  Eric C. Carnes

IPC: A61K9/127 ,  A61K9/51

CPC classification number: A61K9/127 ,  A61K9/1272 ,  A61K9/5115 ,  A61K9/5123 ,  A61K31/713 ,  A61K33/00 ,  A61K33/06 ,  A61K33/24 ,  A61K38/16 ,  A61K39/3955 ,  A61K49/005

Abstract: Various exemplary embodiments provide protocell nanostructures and methods for constructing and using the protocell nanostructures. In one embodiment, the protocell nanostructures can include a core-shell structure including a porous particle core surrounded by a shell of lipid bilayer(s). The protocell can be internalized in a bioactive cell. Various cargo components, for example, drugs, can be loaded in and released from the porous particle core of the protocell(s) and then delivered within the bioactive cell.

Abstract translation: 各种示例性实施方案提供了用于构建和使用原细胞纳米结构的原细胞纳米结构和方法。 在一个实施方案中，原细胞纳米结构可以包括核 - 壳结构，其包括被脂质双层的壳包围的多孔颗粒核。 原细胞可以内化在生物活性细胞中。 可以将各种货物组分，例如药物装载在原细胞的多孔颗粒核心中并从其释放，然后在生物活性细胞内递送。

公开(公告)号：US08715770B2

公开(公告)日：2014-05-06

申请号：US13582883

申请日：2011-03-09

Applicant: Parthiban Selvam ,  Hugh D. C. Smyth ,  Martin Donovan

Inventor： Parthiban Selvam ,  Hugh D. C. Smyth ,  Martin Donovan

IPC: B05D1/12 ,  B05C5/02

CPC classification number: B05B7/144 ,  A61M15/0028 ,  A61M15/0065 ,  A61M15/009 ,  A61M2202/064 ,  A61M2205/0233 ,  A61M2205/0238 ,  B05B12/36 ,  B05B13/0207

Abstract: A device for coating dry powder microparticles onto a surface may include a jet mill configured to mill dry powder particles into microparticles having a desired aerodynamic diameter and to deaggregate the microparticles, a feed hopper structured and arranged to feed dry powder particles to the jet mill, a surface configured to receive dry powder microparticles and an exit nozzle associated with the jet mill. The exit nozzle may be arranged to direct deaggregated micronized dry powder particles from the jet mill to the surface to be coated. The device may further include a holder structured and arranged to hold an item, wherein the item includes the surface. In some aspects of the device, the item may be a film.

Abstract translation: 用于将干燥粉末微粒涂覆到表面上的装置可以包括喷射式粉碎机，其被配置为将干燥粉末颗粒研磨成具有期望的空气动力学直径的微粒并且使微粒解聚，构造并布置成将干燥粉末颗粒送入喷射式粉碎机的进料斗， 被配置为接收干燥粉末微粒的表面和与喷射磨机相关联的出口喷嘴。 出口喷嘴可以布置成将来自喷射磨机的解聚集的微粉化干粉颗粒引导到待涂覆的表面。 该装置还可以包括构造和布置成保持物品的保持器，其中物品包括表面。 在设备的某些方面，该项目可以是电影。

公开(公告)号：US20140110258A1

公开(公告)日：2014-04-24

申请号：US13104200

申请日：2011-05-10

Applicant: Gabriel Lopez ,  Linnea Ista ,  Steven RJ Brueck ,  Aurelio Evangelista Lara ,  Mangesh Bore

Inventor： Gabriel Lopez ,  Linnea Ista ,  Steven RJ Brueck ,  Aurelio Evangelista Lara ,  Mangesh Bore

IPC: G01N27/447

CPC classification number: G01N27/44721 ,  G01N33/5304 ,  G01N33/54366 ,  Y10S977/92

Abstract: Device and method for detecting the presence of known or unknown toxic agents in a fluid sample. Targets in the sample are bound to releasable receptors immobilized in a reaction region of a micro- or nano-fluidic device. The receptors are selected based on their affinity for classes of known toxic agents. The receptors are freed and the bound and unbound receptors separated based on differential electrokinetic mobilities while they travel to a detection device.

Abstract translation: 用于检测流体样品中已知或未知毒物的存在的装置和方法。 样品中的靶标与固定在微流体或纳米流体装置的反应区域中的可释放受体结合。 基于它们对已知毒性剂类的亲和性来选择受体。 受体被释放，并且结合和未结合的受体在移动到检测装置的同时基于差异电动迁移率分离。

公开(公告)号：US08685628B2

公开(公告)日：2014-04-01

申请号：US11739472

申请日：2007-04-24

Applicant: Alexander Raub ,  Andrew Frauenglass ,  Steven R. J. Brueck

Inventor： Alexander Raub ,  Andrew Frauenglass ,  Steven R. J. Brueck

IPC: G03H1/26

CPC classification number: G02B6/1225 ,  B82Y20/00 ,  G02B6/02133 ,  G02B6/4204 ,  G02B2006/12107 ,  G03F7/70408

Abstract: Exemplary embodiments provide methods for patterning large areas, beyond those accessible with the limited single-area exposure techniques, with nanometer scale features. The methods can include forming a grating pattern to make a first interferometric exposure of a first portion of a photosensitive material disposed over a substrate by interfering two or more laser beams, wherein the two or more laser beams comprise an apodized intensity profile having a continuous intensity variation. The method can further include aligning and overlapping the grating pattern to expose a second portion of the photosensitive material such that the first portion and the second portion form a continuous grating pattern.

Abstract translation: 示例性实施例提供了利用纳米尺度特征对大面积图案进行图案化的方法，超出可用有限单面曝光技术访问的区域。 所述方法可以包括形成光栅图案，以通过干涉两个或更多个激光束对布置在基板上的感光材料的第一部分进行第一干涉曝光，其中两个或更多个激光束包括具有连续强度的变迹强度分布 变异。 该方法还可以包括对准和重叠光栅图案以暴露感光材料的第二部分，使得第一部分和第二部分形成连续的光栅图案。

公开(公告)号：US20140061487A1

公开(公告)日：2014-03-06

申请号：US13385457

申请日：2012-02-21

Applicant: Nathan J. Withers ,  Marek A. Osinski ,  Gennady A. Smolyakov

Inventor： Nathan J. Withers ,  Marek A. Osinski ,  Gennady A. Smolyakov

IPC: G01T3/08

CPC classification number: G01T3/00

Abstract: A neutron irradiation history sensor and detection method for detection of thermal neutrons exploit transmutation of 164Dy into 165Ho and 166Er and significant differences in optical properties of Dy, Ho, and Er in order to enable detection of relative fractions of Dy, Ho, and Er and thus the degree and timing of prior thermal neutron exposure that has occurred, providing a tamper-proof forensic record of the prior thermal neutron exposure. The irradiation history sensor and detection method advantageously employ Dy-containing nanocrytals (NCs) residing in a transparent host.

Abstract translation: 用于探测热中子的中子辐射历史传感器和检测方法利用164Dy的转变为165Ho和166Er，并且Dy，Ho和Er的光学性质有显着差异，以便能够检测Dy，Ho和Er的相对分数， 因此已经发生了先前的热中子暴露的程度和时间，提供了先前的热中子暴露的防篡改取证记录。 照射历史传感器和检测方法有利地使用驻留在透明主体中的含Dy纳米颗粒（NC）。

公开(公告)号：US20140038066A1

公开(公告)日：2014-02-06

申请号：US13997545

申请日：2011-12-23

Applicant: Scott Sibbett ,  Carolin Lau ,  Gustavo Pio Marchesi Krall Ciniciato ,  Plamen Atanassov

Inventor： Scott Sibbett ,  Carolin Lau ,  Gustavo Pio Marchesi Krall Ciniciato ,  Plamen Atanassov

IPC: H01M8/04 ,  H01M8/16

CPC classification number: H01M8/04216 ,  H01M8/004 ,  H01M8/023 ,  H01M8/0247 ,  H01M8/0252 ,  H01M8/08 ,  H01M8/1009 ,  H01M8/16 ,  H01M8/2455 ,  Y02E60/527

Abstract: The present disclosure provides biological fuel cells comprising a paper-based fuel delivery layer which delivery fuel to the biological anode and cathode via capillary action and/or evaporation. In some embodiments the paper-based fuel delivery layer incorporates an outwardly extending fan-shaped region which enables a constant volumetric flow rate through the cell.

Abstract translation: 本公开提供了包括纸基燃料输送层的生物燃料电池，其通过毛细作用和/或蒸发将燃料输送到生物阳极和阴极。 在一些实施例中，基于纸的燃料输送层包括向外延伸的扇形区域，其能够通过电池的恒定体积流量。

公开(公告)号：US20140012125A1

公开(公告)日：2014-01-09

申请号：US14021933

申请日：2013-09-09

Applicant: STC.UNM

Inventor： Jingkuang Chen

IPC: A61B5/00

CPC classification number: A61B5/0095 ,  A61B5/0086 ,  A61B5/02007 ,  A61B8/0833 ,  A61B8/12 ,  A61B8/4472 ,  A61B8/4483 ,  A61B8/483 ,  A61B2562/028 ,  Y10T29/49826

Abstract: A photoacoustic medical imaging device may include a substrate, an array of ultrasonic transducers on the substrate, at least one groove etched on the substrate, at least one optical fiber, and at least one facet. Each optical fiber is disposed in one of the grooves. Each facet is etched in one of the grooves and coated with a layer of metal having high infrared reflectivity. Each optical fiber is configured to guide infrared light from a light source through the fiber and toward the respective facet. The facet is configured to reflect the infrared light toward a target.

Abstract translation: 光声医学成像装置可以包括衬底，衬底上的超声换能器阵列，蚀刻在衬底上的至少一个凹槽，至少一个光纤和至少一个面。 每个光纤被布置在一个凹槽中。 每个刻面在一个凹槽中蚀刻并涂覆有具有高红外反射率的金属层。 每个光纤被配置为引导来自光源的红外光通过光纤并朝向相应的刻面。 小面被配置为将红外光反射到目标。

公开(公告)号：US08624968B1

公开(公告)日：2014-01-07

申请号：US12880923

申请日：2010-09-13

Applicant: Stephen D. Hersee ,  Majeed M. Hayat ,  Pradeep Sen

Inventor： Stephen D. Hersee ,  Majeed M. Hayat ,  Pradeep Sen

IPC: H04N9/47 ,  H04N5/243 ,  H04N7/18

CPC classification number: B82Y15/00 ,  B82Y20/00 ,  G02B21/00 ,  G02B21/0004 ,  H01L27/156 ,  H01L33/18 ,  H01L33/24

Abstract: Exemplary embodiments provide microscope devices and methods for forming and using the microscope devices. The microscope device can include a light emitter array with each light emitter individually addressable to either emit or detect light signals. Magnified images of a sample object can be generated by a reflection mechanism and/or a transmission mechanism using one or more microscope devices in an imaging system. Real-time computer control of which microscope pixels are viewed can allow the user to digitally replicate the “fovea” function of human vision. Viewing an object from both sides in the double-sided microscope system and from multiple pixel positions can allow the microscope to reconstruct pseudo-3D images of the object.

Abstract translation: 示例性实施例提供用于形成和使用显微镜装置的显微镜装置和方法。 显微镜装置可以包括光发射器阵列，每个发光器可单独寻址以发射或检测光信号。 可以通过使用成像系统中的一个或多个显微镜装置的反射机构和/或透射机构来生成样品的放大图像。 观察哪个显微镜像素的实时计算机控制可以允许用户数字地复制人类视觉的“中央凹”功能。 从双面显微镜系统和多个像素位置的两侧观察物体可以使显微镜重建物体的伪3D图像。