Fluid injection system
    61.
    发明授权

    公开(公告)号:US4938262A

    公开(公告)日:1990-07-03

    申请号:US180423

    申请日:1988-04-11

    IPC分类号: A61L2/24 G01F11/08

    CPC分类号: G01F11/086 A61L2/24

    摘要: A cassette containing a group of sealed cells is used as a means for delivering doses of fluid to be injected into a sterilizing chamber. After the cassette is automatically positioned over a piercing mechanism, the cassette is moved downwardly so that a cell is pierced. Fluid is then forced out of the cell by pneumatic pressure into an injector valve, which opens in a manner which does not adversely affect a vacuum within the chamber.

    Method and apparatus for overpressure protection of a catheter
    63.
    发明授权
    Method and apparatus for overpressure protection of a catheter 失效
    导管超压保护方法及装置

    公开(公告)号:US6033393A

    公开(公告)日:2000-03-07

    申请号:US775409

    申请日:1996-12-31

    摘要: A method and apparatus for overpressure protection of a catheter from an indwelling catheter. A method in one embodiment includes injecting an agent into the catheter and relieving overpressures in the catheter during the injecting step. The agent is typically a declotting agent and the obstruction is typically a clot (e.g., blood clot). In one embodiment of the apparatus, a catheter includes a cannula and a first hub and a second hub, each of which are coupled to the cannula. The first hub is for receiving an agent which is placed into the cannula to remove an obstruction, and the second hub includes an overpressure relief valve for relieving an overpressure condition in the cannula. Other embodiments of the invention are also described.

    摘要翻译: 一种用于从留置导管超导保护导管的方法和装置。 在一个实施方案中的方法包括将药剂注射到导管中并在注射步骤期间释放导管中的超压。 该药剂通常是一种去酸剂,阻塞物通常是凝块(例如血块)。 在该装置的一个实施例中,导管包括套管和第一轮毂以及第二轮毂,每个毂联接到套管。 第一轮毂用于接收放置在套管中以除去障碍物的药剂,并且第二轮毂包括用于缓解套管中的超压状况的超压安全阀。 还描述了本发明的其它实施例。

    Composite surgical material
    64.
    发明授权
    Composite surgical material 失效
    复合手术材料

    公开(公告)号:US6015844A

    公开(公告)日:2000-01-18

    申请号:US995228

    申请日:1997-12-19

    摘要: A composite surgical material comprising a collagen matrix reinforced by a layer of a synthetic bioabsorbable material such as polylactide/polyglycolide or oxidised regenerated cellulose, and wherein oil droplets are dispersed in the collagen matrix. The oil droplets comprise 1% to 75% of the weight of the composite and result in improved leak-proofing of the composite. The composite, in the form of a sheet or a tube, is especially useful as a temporary, fully bioabsorbable prosthesis, for membranes or blood vessels where a highly leak-proof prosthesis is required. The invention also provides a method of making a composite surgical material comprising the steps of: providing a layer of a synthetic bioabsorbable material; providing a dispersion of collagen in an oil-in-water emulsion; coating at least one face of the layer of synthetic bioabsorbable material with the said dispersion; and drying the composite material thus obtained.

    摘要翻译: 一种复合手术材料,其包含由合成的生物可吸收材料层如聚丙交酯/聚乙交酯或氧化的再生纤维素增强的胶原基质,并且其中油滴分散在胶原基质中。 油滴占复合材料重量的1%至75%,从而改善了复合材料的防漏性能。 以片或管的形式的复合材料作为需要高度防漏假体的膜或血管的临时的,完全生物可吸收的假体是特别有用的。 本发明还提供一种制备复合外科材料的方法,包括以下步骤:提供合成的生物可吸收材料的层; 提供胶原蛋白在水包油乳液中的分散体; 用所述分散体涂覆合成的生物可吸收材料层的至少一个面; 并干燥由此获得的复合材料。

    Lumen device reprocessor without occlusion
    65.
    发明授权
    Lumen device reprocessor without occlusion 失效
    流明装置重新处理器无遮挡

    公开(公告)号:US6013227A

    公开(公告)日:2000-01-11

    申请号:US992602

    申请日:1997-12-17

    摘要: A method for cleaning/sterilizing a device having a lumen with at least two open ends comprises the steps of: a) providing a container having at least one enclosure and at least one interface separating the enclosure from the container, the interface having at least one opening thereon, b) placing the device across the opening with one open end in the container and another open end in the enclosure, c) generating a flow of a cleaning solution through the lumen to clean the inner surface of the lumen, d) generating a flow of rinse solution through the lumen to rinse the inner surface of the lumen, e) treating the device with a chemical germicide, and f) adjusting the opening in any of steps c) to e) to reduce the areas on surface of the device occluded by contacting with the opening. An apparatus for cleaning/sterilizing a lumen device comprises a container having a fluid port for flowing and draining a fluid in and out the container. At least one enclosure is coupled with the container for receiving part of the lumen device so that one end of the lumen device is located in the enclosure and the other end of the lumen device is located in the container. An interface separates the container and enclosure. At least one openable and closable holder sealably is coupled to the interface. A source for creating a pressure difference between the container and the enclosure. A cleaning mechanism adapted to clean the device in the container or enclosure is also provided.

    摘要翻译: 一种用于清洁/消毒具有至少两个开放端的内腔的装置的方法包括以下步骤:a)提供容器,该容器具有至少一个外壳和至少一个将容器与容器隔开的界面,该界面具有至少一个 b)将容器中的一个开口端和外壳中的另一个开口端放置在开口上,c)通过内腔产生清洁溶液的流动,以清洁内腔的内表面,d)产生 漂洗溶液流过内腔以冲洗内腔的内表面,e)用化学杀菌剂处理该装置,以及f)在步骤c)至e)中的任何步骤中调节开口以减少表面上的面积 装置通过与开口接触而封闭。 用于清洁/消毒管腔装置的装置包括具有用于使流体流入和排出容器的流体端口的容器。 至少一个外壳与容器联接以容纳管腔装置的一部分,使得管腔装置的一端位于外壳中,并且管腔装置的另一端位于容器中。 界面将容器和外壳分开。 至少一个可打开和可关闭的保持器可密封地联接到界面。 用于在容器和外壳之间产生压力差的源。 还提供了适于清洁容器或外壳中的装置的清洁机构。

    Preparation of autologous plasma and fibrin gel
    66.
    发明授权
    Preparation of autologous plasma and fibrin gel 失效
    自体血浆和纤维蛋白凝胶的制备

    公开(公告)号:US6001259A

    公开(公告)日:1999-12-14

    申请号:US935831

    申请日:1997-09-23

    申请人: Elaine Whitmore

    发明人: Elaine Whitmore

    摘要: A system for preparing autologous plasma comprises a single use filter unit having two inlets in fluid communication with each other, an outlet, and a filtration membrane selectively permeable to blood plasma separating the inlets from the outlet. Manually operable, single use pumps, preferably syringes, connect to the inlets. A flow path is defined along the membrane between the pumps, whereby, whole blood can be repeatedly exchanged between the two pumps, past the membrane, to cause plasma to flow across the membrane and out of the outlet. A syringe can collect plasma from the outlet. Plasma thus collected can be simultaneously applied with a thrombin solution to a site on the body, thereby forming a fibrin gel.

    摘要翻译: 用于制备自体血浆的系统包括具有彼此流体连通的两个入口的单一使用过滤器单元,出口和对入口分离出血液的选择性渗透的过滤膜。 手动可操作的单次使用泵,优选注射器,连接到入口。 沿着泵之间的膜定义流动路径,由此,全血可以在两个泵之间经过膜重复交换,以使等离子体流过膜并离开出口。 注射器可以从出口收集血浆。 如此收集的血浆可以同时施用凝血酶溶液到身体上的部位,从而形成纤维蛋白凝胶。

    Chemical indicator for oxidation-type sterilization processes using
bleachable dyes
    67.
    发明授权
    Chemical indicator for oxidation-type sterilization processes using bleachable dyes 失效
    使用可漂白染料的氧化型灭菌方法的化学指示剂

    公开(公告)号:US5942438A

    公开(公告)日:1999-08-24

    申请号:US966397

    申请日:1997-11-07

    CPC分类号: A61L2/28 C12Q1/22 G01N31/226

    摘要: A method and apparatus for detecting exposure to an oxidation-type sterilant using a chemical indicator comprising bleachable dye is disclosed. Using the method and apparatus disclosed, a bleachable azo dye is incorporated with an anodized aluminum or chromate conversion coated surface and exposed to an oxidation-type sterilant, such as hydrogen peroxide, and inspected upon completion of the sterilization process for color change. If exposed to sterilant for an appropriate amount of time the bleachable dye changes color thereby indicating adequate sterilization. The surface incorporating bleachable dye may be made to change color after a predetermined number of exposures to a oxidation-type sterilant.

    摘要翻译: 公开了一种使用包含可漂白染料的化学指示剂检测暴露于氧化型杀菌剂的方法和装置。 使用所公开的方法和装置,将可漂白的偶氮染料与阳极氧化的铝或铬酸盐转化涂覆的表面结合并暴露于氧化型灭菌剂如过氧化氢,并且在完成用于颜色变化的灭菌过程后检查。 如果将杀菌剂暴露于适当的时间,则可漂白染料会改变颜色,从而指示适当的灭菌。 包含可漂白染料的表面可以在预定数量的暴露于氧化型杀菌剂之后变色。

    Endoscope with improved flexible insertion tube
    69.
    发明授权
    Endoscope with improved flexible insertion tube 失效
    内窥镜具有改进的柔性插管

    公开(公告)号:US5876331A

    公开(公告)日:1999-03-02

    申请号:US747689

    申请日:1996-11-12

    摘要: In a flexible endoscope having a flexible insertion tube comprising a tubular, biocompatible elastomeric outer covering thereabout which encloses an interior space, the improvement according to the present invention comprises a vapor barrier between the outer covering and the interior space. Thus, vapor, such as hydrogen peroxide or other sterilants, passing through the outer covering from an atmosphere thereabout is prevented from entering the interior space by the vapor barrier. Further, the vapor is thus prevented from interacting with substances, such as lubricants, within the interior space to produce agents harmful to the elastomeric covering.

    摘要翻译: 在具有柔性插入管的柔性内窥镜中,柔性插入管包括围绕内部空间的管状的生物相容的弹性体外覆盖层,根据本发明的改进包括在外覆盖物和内部空间之间的蒸气阻挡层。 因此,通过蒸汽屏障防止从其周围的大气通过外覆盖层的蒸气,例如过氧化氢或其它灭菌剂进入内部空间。 此外,因此防止蒸气与内部空间内的物质如润滑剂相互作用,以产生对弹性体覆盖物有害的试剂。