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    DEVICE AND KIT FOR INDICATING A PH AT A LOCUS
    64.
    发明申请
    DEVICE AND KIT FOR INDICATING A PH AT A LOCUS 审中-公开

    公开(公告)号：US20190008428A1

    公开(公告)日：2019-01-10

    申请号：US16070260

    申请日：2017-01-13

    Applicant: SMITH & NEPHEW PLC ,  UNIVERSITY OF SHEFFIELD

    Inventor： John Kenneth HICKS ,  Richard HOSKINS ,  Stephen RIMMER ,  Dorothy MCCULLOCH

    IPC: A61B5/145 ,  A61B5/00 ,  A61F13/84 ,  A61F15/00 ,  G01N31/22 ,  A61L15/42 ,  A61L15/26 ,  A61L15/24

    Abstract: Device comprising polyurethane material for indicating pH at a locus, preferably as indication of presence of microbes, comprising a polyurethane network having immobilised therein one or more hydrophilic copolymers, the or each said copolymer comprising:hydrophilic monomer; and indicator monomer, which provides an indication in response to a change in hydrophilic state of said hydrophilic monomer and/or copolymer; characterised in that the or each copolymer further comprises one or a plurality of ionisable groups or moieties or polymerisable monomers having one or more characteristic pKa values in the range 5 to 10 and which are responsive to pH at the locus in the range pH 5 to pH 10 and in that hydrophilic state of hydrophilic copolymer is dependent on ionisation of said ionisable groups, moieties or monomers; kit and device comprising the material and process for preparation thereof; and use in detecting or sensing microbes or pH.

    NECK ORTHOSIS
    67.
    发明申请
    NECK ORTHOSIS 审中-公开

    公开(公告)号：US20160074202A1

    公开(公告)日：2016-03-17

    申请号：US14889828

    申请日：2014-05-09

    Applicant: THE UNIVERSITY OF SHEFFIELD

    Inventor： Alexander Heathcliff REED ,  Joseph LANGLEY ,  Andrew STANTON ,  Nicola HERON ,  Christopher MCDERMOTT

    IPC: A61F5/055

    CPC classification number: A61F5/055

    Abstract: A neck orthosis, head support system and method of use for supporting a head of a patient having a medical condition are described. The neck orthosis can comprise a body made of a material which is flexible and stretchy and a releasable fastener. The neck orthosis is shaped to cause the neck orthosis snuggly to conform to the anatomy of the patient adjacent the neck of the patient when the neck support is secured in use about the neck of the patient by the releasable fastener to support the head of the patient. A head support system can include a plurality of different support members which can be releasably attached to the neck orthosis to provide different types of support to the head of the patient.

    Abstract translation: 描述了颈部矫形器，头部支撑系统和用于支撑具有医疗状况的患者的头部的使用方法。 颈部矫形器可以包括由柔性和弹性的材料制成的主体和可释放的紧固件。 颈部矫形器被成形为当颈部支撑件通过可释放的紧固件在患者的颈部被固定以支撑患者的头部时，使得颈部矫形器紧贴符合患者颈部的患者的解剖结构 。 头部支撑系统可以包括多个不同的支撑构件，其可以可释放地附接到颈部矫形器，以向患者头部提供不同类型的支撑。

    REINFORCED POLYMER COMPOSITES FROM RECYCLED PLASTIC
    69.
    发明申请
    REINFORCED POLYMER COMPOSITES FROM RECYCLED PLASTIC 有权
    回收塑料的增强聚合物复合材料

    公开(公告)号：US20160017131A1

    公开(公告)日：2016-01-21

    申请号：US14335867

    申请日：2014-07-18

    Applicant: QATAR UNIVERSITY ,  THE UNIVERSITY OF SHEFFIELD

    Inventor： MARIAM ALALI ALMAADEED ,  NABIL MADI ,  ALMA HODZIC ,  SARAVANAN RAJENDRAN

    IPC: C08L23/06

    CPC classification number: C08L23/06 ,  C08K3/34 ,  C08K7/02 ,  C08L23/10 ,  C08L2205/025 ,  C08L2205/03 ,  C08L2207/062 ,  C08L2207/066 ,  C08L2207/20

    Abstract: The reinforced polymer composites from recycled plastic are polymer blends made from recycled polymers that are reinforced with glass fibers and mica. In particular, the reinforced polymer composites are blends of recycled low-density polyethylene (LDPE), high-density polyethylene (HDPE), and polypropylene (PP) with a mica filler that are reinforced with glass fibers, where the low-density polyethylene forms between 30 wt % and 35 wt % of the composite, the high-density polyethylene forms between 15 wt % and 17.5 wt % of the composite, the polypropylene forms between 15 wt % and 17.5 wt % of the composite, the glass fibers form between 15 wt % and 40 wt % of the composite, and the mica forms up to 15 wt % of the structural element. The resultant reinforced polymer composite has a relatively high heat deflection temperature, good mechanical properties (such as increased stiffness and strength), improved thermal stability, and is cost effective to manufacture.

    Abstract translation: 来自再生塑料的增强聚合物复合材料是由玻璃纤维和云母增强的再循环聚合物制成的聚合物共混物。 特别地，增强聚合物复合材料是再生低密度聚乙烯（LDPE），高密度聚乙烯（HDPE）和聚丙烯（PP）与玻璃纤维增​​强的云母填料的混合物，其中低密度聚乙烯形成 在复合材料的30重量％至35重量％之间，高密度聚乙烯形成复合材料的15重量％至17.5重量％之间，聚丙烯形成复合材料的15重量％至17.5重量％之间，玻璃纤维之间形成 15重量％和40重量％的复合材料，并且云母形成至多15重量％的结构元件。 所得的增强聚合物复合材料具有相对较高的热变形温度，良好的机械性能（例如增加的刚度和强度），改善的热稳定性，并且制造成本有效。

    MEDIA FOR STEM CELLS
    70.
    发明申请
    MEDIA FOR STEM CELLS 审中-公开
    干细胞培养基

    公开(公告)号：US20150376567A1

    公开(公告)日：2015-12-31

    申请号：US14769724

    申请日：2014-02-21

    Applicant: THE UNIVERSITY OF SHEFFIELD

    Inventor： Irene Canton ,  Steven Peter Armes ,  Nicholas John Warren ,  Harry Moore ,  Guiseppe Battaglia ,  Denis Cecchin

    IPC: C12N5/00

    CPC classification number: C12N5/0068 ,  C12N2533/40 ,  C12N2539/10

    Abstract: The present invention relates to a medium for storing, preserving, culturing, and/or differentiating stem cells. The medium employs a synthetic thermo-responsive copolymer, dispersed in an aqueous vehicle, which allows the medium to be readily “switched” between a non-gelatinous (fluid) form and a gelatinous form by simply adjusting temperature across the gelling temperature of the medium. As such, stem cells can be easily captured within a 3D gel matrix by simply mixing the stem cells with the non-gelatinous/fluid form of the medium and then gelling the medium by adjusting the temperature across the gelling temperature of the medium. The stem cells encapsulated within the gelatinous form of the medium may then be preserved for a significant time period before either using the stem cells directly within the medium (e.g. in therapy, or in culturing, differentiation, and such like), or after their extraction from the medium.

    Abstract translation: 本发明涉及用于储存，保存，培养和/或分化干细胞的培养基。 该介质使用分散在水性载体中的合成热响应性共聚物，其允许介质通过简单地调节介质的凝胶化温度之间的温度而容易地在非凝胶状（流体）形式和凝胶状之间“转换” 。 因此，通过简单地将干细胞与培养基的非凝胶状/流体形式混合，然后通过调节培养基的凝胶化温度的温度来胶化培养基，可以容易地在3D凝胶基质内捕获干细胞。 然后可以将包封在培养基中的干胶质细胞形式的干细胞保持一段相当长的时间，直到在培养基中直接使用干细胞（例如在治疗或培养，分化等）或在其提取后 从媒介。

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