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公开(公告)号：US5362291A
公开(公告)日：1994-11-08
申请号：US193908
申请日：1994-02-09
CPC分类号： B04B5/0428 , B04B5/0442 , B04B7/02 , B04B2005/045 , B04B2005/0492
摘要： A drawer-mounted centrifuge provides easy access for loading and unloading disposable processing elements. The centrifuge also includes an umbilicus holder that moves between an operating position and an out-of-the-way position as the drawer opens and closes.
摘要翻译： 抽屉式离心机可轻松访问一次性处理元件的装载和卸载。 离心机还包括一个脐保持器，当抽屉打开和关闭时，它能够在操作位置和不通过位置之间移动。
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62.发明授权Pivot pin bearing/seal with loose eyelet especially suited for disposable continuous flow blood filtration system cartridges 失效枢轴销/密封件，松动的孔眼，特别适合一次性连续流血过滤系统墨盒
公开(公告)号：US4965846A
公开(公告)日：1990-10-23
申请号：US262259
申请日：1988-10-20
摘要： A pivot pin bearing/seal especially adapted for supporting the rotor of a disposable filtration cartridge of a continuous-flow plasmapheresis blood separation system includes a lubricious plastic pivot pin injection molded with a recess at its end. The recess is surrounded by a sharp circular inside edge. A stainless steel eyelet, deep drawn from successive dies, is loosely inserted into the pin recess, a radial outer surface defined at the junction between the eyelet shank and the eyelet flange contacting the pin sharp edge. The eyelet rotates relative to the pin, the circular line path of rotational contact being defined by the smooth curved surface under the flange of the eyelet and the sharp inside edge surrounding the pin recess which quickly burnishes to a good rotational seal. A silicon elastomer seal ring is disposed between the eyelet flange and the rotating filtration rotor to establish a fluid-tight essentially non-rotating seal between the eyelet and the rotor (and therefore causing the eyelet to rotate with the rotor relative to the pin). Coaxial sealing structures may be provided in cascade-type filter cartridges.
摘要翻译： 特别适于支撑连续流动血浆分离系统的一次性过滤筒的转子的枢轴销轴承/密封件包括在其端部注射模制凹槽的润滑塑料枢轴销。 凹槽由尖锐的圆形内边缘包围。 从连续模具深度拉出的不锈钢孔眼松动地插入销凹槽中，限定在孔眼柄和孔眼法兰之间的接合处的径向外表面接触销尖锐边缘。 孔眼相对于销钉旋转，旋转接触的圆形路径由孔眼凸缘下方的光滑曲面和围绕销凹槽的尖锐的内部边缘限定，其快速地被磨光到良好的旋转密封。 硅橡胶密封环设置在孔眼凸缘和旋转的过滤转子之间，以在孔眼和转子之间建立流体密封的基本上不旋转的密封（并且因此导致孔眼相对于销子与转子一起旋转）。 同轴密封结构可以设置在级联型滤芯中。
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公开(公告)号：US20140025058A1
公开(公告)日：2014-01-23
申请号：US13741261
申请日：2013-01-14
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B18/1482 , A61B2017/00084 , A61B2018/00023 , A61B2018/00291
摘要： An electrosurgical end effector for ablating tissue is provided that comprises at least one electrically-conductive ablation member adapted to be connected to a source of RF energy, with the ablation member having a tissue engaging surface and defining an internal fluid passageway. Preferably, the end effector includes two electrically conductive ablation members that are electrically isolated from one another and have their fluid passageways in fluid communication. Alternatively, the end effector may comprise four electrically conductive ablation members arranged as two pairs of ablation members, all of the ablation members having internal fluid passageways that are electrically isolated from each other, with the fluid passageways of each of the four ablation members being in fluid communication with each other.
摘要翻译： 提供了用于烧蚀组织的电外科末端执行器，其包括适于连接到RF能量源的至少一个导电消融部件，消融部件具有组织接合表面并限定内部流体通道。 优选地，末端执行器包括彼此电隔离并且使其流体通道处于流体连通的两个导电消融构件。 或者，末端执行器可以包括布置成两对消融构件的四个导电消融构件，所有的消融构件具有彼此电隔离的内部流体通道，四个消融构件中的每一个的流体通道在 相互流通。
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公开(公告)号：US08623300B2
公开(公告)日：2014-01-07
申请号：US13610204
申请日：2012-09-11
CPC分类号： G01N1/36 , A61B10/0096 , B01L3/508 , B01L2300/043 , B01L2300/046 , B01L2300/069 , B01L2300/0809 , G01N1/31 , Y10T436/25
摘要： A histologic tissue sample support device includes a tissue support formed of material that can be successfully sectioned in a microtome and is resistant to degradation from solvents and chemicals used to fix, process and stain tissue. A resilient cellular material is coupled to the tissue support and is configured to engage and retain tissue in place during processing and embedding. The resilient cellular material is also capable of successful sectioning in the microtome and porous to allow infiltration of the solvents and chemicals used to fix, process and stain tissue, and of embedding material used to embed the tissue while the tissue is retained by the resilient cellular material.
摘要翻译： 组织学组织样本支持装置包括由材料形成的组织支架，其可以成功地切片在切片机中并且耐受用于固定，处理和染色组织的溶剂和化学品的降解。 弹性细胞材料联接到组织支撑件并且构造成在处理和嵌入期间接合并保持组织就位。 弹性细胞材料还能够在切片机中成功切片并且多孔，以允许用于固定，处理和染色组织的溶剂和化学品的浸透，以及嵌入用于嵌入组织的材料，同时组织被弹性细胞保留 材料。
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65.发明申请公开(公告)号：US20100167334A1
公开(公告)日：2010-07-01
申请号：US12647701
申请日：2009-12-28
CPC分类号： G16H10/40
摘要： A system for processing tissue biopsy samples during a histopathology process, including a tissue carrier constructed to carry a tissue biopsy sample during at least one step of the histopathology process, a database storing information associated with the tissue biopsy sample and associated with a tissue processing procedure, a machine-readable indicator physically associated with the tissue carrier, the machine-readable indicator including a machine-readable reference identified with the tissue biopsy sample, and an electronic control operative to read the reference, access the information in the database using the reference, and implement at least a portion of the tissue processing procedure in accordance with the accessed information.
摘要翻译： 一种用于在组织病理学过程中处理组织活组织检查样品的系统，包括构建成在组织病理学过程的至少一个步骤期间携带组织活检样品的组织载体，存储与组织活检样品相关联的信息并与组织处理程序相关联的数据库 与所述组织载体物理相关联的机器可读指示器，所述机器可读指示器包括用所述组织活检样本识别的机读参考，以及用于读取所述参考的电子控制器，使用所述参考来访问所述数据库中的信息 并且根据所访问的信息实现组织处理过程的至少一部分。
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公开(公告)号：US20090012545A1
公开(公告)日：2009-01-08
申请号：US11994725
申请日：2006-07-14
申请人： Warren P. Williamson, IV , Jason I. Glithero , Michael W. Goldenbogen , Chadd R. Tyler , Todd A. Hall
发明人： Warren P. Williamson, IV , Jason I. Glithero , Michael W. Goldenbogen , Chadd R. Tyler , Todd A. Hall
IPC分类号： A61B17/122
CPC分类号： A61B17/083 , A61B17/10 , A61B17/1227 , A61B17/1285 , A61B2017/00004
摘要： A clamp (10) having at least first and second elongate clamping portions (2, 4) adapted to be placed on opposite sides of the hollow anatomical structure (40). The first and second elongate clamping portions (2, 4) respectively include ends coupled together with respective resilient urging members (6, 8) configured to urge at least one of the first and second elongate clamping portions (2, 4) toward the other of the first and second elongate clamping portions (2, 4) from an open position into a clamping position to occlude the hollow anatomical structure (40). The clamp (10) is shaped annularly such that it may surround the hollow anatomical structure (40) in the open position and reorient into a flattened shape in the clamping position to occlude the hollow interior of the hollow anatomical structure (40). Apparatus of the invention further include clamp delivery and actuation devices (80, 200) adapted to deploy the clamp (10).
摘要翻译： 具有适于放置在中空解剖结构（40）的相对侧上的至少第一和第二细长夹紧部分（2,4）的夹具（10）。 第一和第二细长夹紧部分（2,4）分别包括与相应的弹性推动构件（6,8）联接在一起的端部，其构造成将第一和第二细长夹紧部分（2,4）中的至少一个朝向另一个 所述第一和第二细长夹持部分（2,4）从打开位置进入夹紧位置以封闭所述中空解剖结构（40）。 夹具（10）环形地成形，使得其可以围绕处于打开位置的中空解剖结构（40）并且在夹紧位置中重新定向成扁平形状以闭塞中空解剖结构（40）的中空内部。 本发明的装置还包括适于展开夹具（10）的夹具输送和致动装置（80,200）。
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67.发明授权
公开(公告)号：US5817093A
公开(公告)日：1998-10-06
申请号：US743321
申请日：1996-11-04
IPC分类号： A61B17/072 , A61B17/115 , A61B17/32 , A61B18/12 , A61B18/14 , A61B19/00 , A61B17/36
CPC分类号： A61B18/1447 , A61B17/07207 , A61B18/1206 , A61B17/115 , A61B17/32 , A61B18/1402 , A61B18/1442 , A61B2018/00404 , A61B2018/00601 , A61B2018/00642 , A61B2018/00666 , A61B2018/00672 , A61B2018/00678 , A61B2018/00684 , A61B2018/00702 , A61B2018/00708 , A61B2018/00761 , A61B2018/00875 , A61B2018/00886 , A61B2018/1273 , A61B2018/1861 , A61B2090/032
摘要： Query electrodes are provided for monitoring the electrical impedance of tissue as it is treated with electrosurgical energy. In one embodiment, based on a predicted model of tissue impedance and a number of initial impedance readings, the impedance at which tissue treatment is completed is predicted. More particularly, a minimum impedance level is measured and a function of the minimum impedance is used to determine impedance at which coagulation is completed. A control device is provided for bringing the output of the generator within an optimum range based on a system load curve. In one embodiment the impedance monitoring device is used in conjunction with a bipolar electrosurgical instrument. Preferably, the instrument comprises electrically opposite therapeutic electrodes, each located on one or more tissue engaging surfaces for engaging tissue to be treated, and electrically opposite query electrodes, located on one or more tissue engaging surfaces. The therapeutic electrodes provide therapeutic energy to the tissue while the query electrodes provide a lower voltage electrical sensing energy for the purpose of measuring tissue impedance at various stages, e.g. before, during, or after tissue treatment.
摘要翻译： 提供查询电极，用于监测组织在电外科手术能量下的电阻抗。 在一个实施例中，基于组织阻抗的预测模型和初始阻抗读数的数量，预测组织处理完成时的阻抗。 更具体地，测量最小阻抗水平，并且使用最小阻抗的函数来确定凝结完成的阻抗。 提供了一种控制装置，用于基于系统负载曲线使发电机的输出达到最佳范围。 在一个实施例中，阻抗监测装置与双极电外科器械结合使用。 优选地，该仪器包括电对立的治疗电极，每个电极位于一个或多个组织接合表面上，用于接合待治疗的组织，以及位于一个或多个组织接合表面上的电气相对的查询电极。 治疗电极为组织提供治疗能量，而查询电极提供较低电压的电感测能量，用于在各个阶段例如测量组织阻抗。 组织治疗之前，期间或之后。
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公开(公告)号：US5630541A
公开(公告)日：1997-05-20
申请号：US360460
申请日：1994-12-21
IPC分类号： A61B17/072 , A61B17/32
CPC分类号： A61B17/07207 , A61B17/32 , A61B2017/07278
摘要： A surgical stapler comprising at least one cam having a cam surface, an arrangement for actuating the cam for a longitudinal firing movement of the cam surface, a cartridge having a plurality of staple drive members driven by the longitudinal movement of the cam surface, and a plurality of surgical staples respectively associated with the staple drive members for being fired by the longitudinal movement of the cam surface. In one embodiment of the present invention, the staple drive members include at least a pair of alternating first and second staple drive members, the first staple drive member including a laterally spaced pair of staple driving surfaces, the second staple drive member including a single staple driving surface. The first and second staple drive members are disposed such that the staple driving surfaces thereof are arranged in laterally spaced three rows. Alternate embodiments include drive members each having a pair of longitudinally aligned driving surfaces, and a third laterally offset driving surface, as well as a spine-like flexible drive element operatively positioned between the cam surface of the cam and the drive members.
摘要翻译： 一种手术吻合器，包括至少一个具有凸轮表面的凸轮，用于致动所述凸轮以用于所述凸轮表面的纵向点火运动的装置，具有由所述凸轮表面的纵向运动驱动的多个订书钉驱动构件的盒， 分别与钉驱动构件相关联的多个外科缝合钉，用于通过凸轮表面的纵向运动而被击发。 在本发明的一个实施例中，钉驱动构件包括至少一对交替的第一和第二钉驱动构件，第一钉驱动构件包括横向间隔开的一对钉驱动表面，第二钉驱动构件包括单个钉 驾驶面。 第一和第二钉驱动构件被布置成使得其钉驱动表面布置成横向间隔开的三排。 替代实施例包括各自具有一对纵向对准的驱动表面和第三横向偏移驱动表面的驱动构件，以及可操作地定位在凸轮的凸轮表面和驱动构件之间的脊状柔性驱动元件。
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公开(公告)号：US4753729A
公开(公告)日：1988-06-28
申请号：US727585
申请日：1985-04-26
IPC分类号： G01N33/48 , A61M1/00 , A61M1/22 , A61M1/26 , A61M1/34 , B01D63/16 , B04B5/00 , B04B9/02 , F16J15/34 , F16J15/50 , G01N1/00 , H02K5/128 , H02K49/10 , B01D17/038
CPC分类号： F16J15/34 , A61M1/262 , B01D61/08 , B01D63/062 , B01D63/16 , F16J15/50 , H02K49/106 , A61M1/3496 , B01D2313/12 , B01D2315/02 , H02K5/128
摘要： A disposable biomedical rotating filtration system for processing fluids in a closed environment includes a rotor mounted for rotation on a pivot pin, a seal between the rotor and pivot pin, an external permanent magnet drive mechanism, and a star shaped drive element mounted on the rotor for rotating the rotor in response to a magnetic field induced by the permanent magnet of the drive mechanism. The drive element on the rotor is stamped from an inexpensive non-permanent ferromagnetic sheet metal and has a configuration and position in relation to the center of said magnetic field such that said drive element receives sufficient torque for driving said rotor and sufficient seal force is applied on the rotor to provide fluid tight seal between the rotating rotor and the seal. The pivot pin is molded from a hard plastic material such as a polyamide base resin having a low coefficient of friction and good lubriciousness. The pivot pin is irradiated by gamma radiation for sterilization and modifying of the plastic material without degradation or loss of lubricious properties.
摘要翻译： 用于在封闭环境中处理流体的一次性生物医学旋转过滤系统包括安装在枢轴销上的转子，转子和枢转销之间的密封件，外部永磁体驱动机构和安装在转子上的星形驱动元件 用于响应于由驱动机构的永磁体感应的磁场来旋转转子。 转子上的驱动元件由便宜的非永久性铁磁金属板冲压而成，并且具有相对于所述磁场中心的构造和位置，使得所述驱动元件接收足够的转矩来驱动所述转子并施加足够的密封力 在转子上提供旋转转子和密封件之间的流体密封。 枢轴销由诸如具有低摩擦系数和良好光滑性的聚酰胺基础树脂的硬塑料材料模制而成。 枢轴销被γ射线照射，用于塑料材料的灭菌和改性，而不降解或丧失润滑性能。
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公开(公告)号：US10166024B2
公开(公告)日：2019-01-01
申请号：US13194152
申请日：2011-07-29
申请人： Warren P. Williamson, IV , Jason I. Glithero , Michael W. Goldenbogen , Chadd R. Tyler , Todd A. Hall , Delos M. Cosgrove
发明人： Warren P. Williamson, IV , Jason I. Glithero , Michael W. Goldenbogen , Chadd R. Tyler , Todd A. Hall , Delos M. Cosgrove
IPC分类号： A61B17/122 , A61B17/08 , A61B17/10 , A61B17/128 , A61B17/00
摘要： A clamp having at least first and second elongate clamping portions adapted to be placed on opposite sides of the hollow anatomical structure. The first and second elongate clamping portions respectively include ends coupled together with respective resilient urging members configured to urge at least one of the first and second elongate clamping portions toward the other of the first and second elongate clamping portions from an open position into a clamping position to occlude the hollow anatomical structure. The clamp includes tissue ingrowth structure on the clamping portions.
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