公开(公告)号：US20240086756A1

公开(公告)日：2024-03-14

申请号：US18226785

申请日：2023-07-27

Applicant: Fujitsu Limited ,  OSAKA UNIVERSITY

Inventor： Jun FUJISAKI ,  Hirotaka OSHIMA ,  Keisuke FUJII

IPC: G06N10/70 ,  G06N10/20

CPC classification number: G06N10/70 ,  G06N10/20

Abstract: An information processing apparatus determines a combination of a first data qubit and a second data qubit that further reduces the energy represented by an energy equation. The energy equation includes first to third energy terms. The first energy term is used to identify the first data qubit on which a Z error has occurred. The second energy term is used to identify the second data qubit on which an X error has occurred. The third energy term reduces the energy as the number of data qubits each being a third data qubit on which both a Z error and an X error have simultaneously occurred increases. The information processing apparatus determines that a Y error has occurred on the third data qubit.

公开(公告)号：US20240065992A1

公开(公告)日：2024-02-29

申请号：US18266070

申请日：2021-12-10

Applicant: KINKI UNIVERSITY ,  YASHIRO CO., LTD. ,  OSAKA UNIVERSITY

Inventor： Nobuhiro ZAIMA ,  Hirona KUGO ,  Motohiro KITANO ,  Yoshinori HIROTA ,  Ken-ichi HIRANO

IPC: A61K31/19 ,  A61P9/00

CPC classification number: A61K31/19 ,  A61P9/00

Abstract: An aortic aneurysm has few noticeable symptoms and is at high risk of rupture without a sign of abnormality. Further, if the aortic aneurysm ruptures, it causes a shock state due to massive blood loss and results in a very low survival rate. Thus, when the aortic aneurysm is found by physical examination or the like, surgery with a stent graft or the like needs to be performed according to the state of its progression.
A pharmaceutical composition for preventing and treating an aortic aneurysm including a medium chain fatty acid as a main component has an effect of inhibiting the occurrence and progression of the aortic aneurysm. Thus, when the aortic aneurysm is found, continuous intake of the composition can not only inhibit the progression of the aortic aneurysm but also mediate the regression of the aortic aneurysm, thereby producing the effect of improving vital prognosis.

公开(公告)号：US20240055139A1

公开(公告)日：2024-02-15

申请号：US18030990

申请日：2021-10-12

Applicant: OSAKA UNIVERSITY

Inventor： Ken NAKATA ,  Yasushi SAKATA ,  Keita YAMASAKI ,  Teruki YOKOYAMA ,  Shoji KONDA

IPC: G16H50/80 ,  A61B5/0205 ,  A61B5/024 ,  A61B5/11

CPC classification number: G16H50/80 ,  A61B5/02055 ,  A61B5/024 ,  A61B5/11

Abstract: An apparatus (1) includes an exercise sensor (31) that continuously detects a movement of an exerciser accompanied by intermittent exercise, and a heart rate meter (32) that continuously measures a heart rate of the exerciser, and further includes an activity detection unit (12), a heart rate monitoring unit (13), an activity monitoring unit (14), and a notification processing unit (15). The activity detection unit (12) detects, from the movement of the exerciser, an activity intensity, a high activity intensity period, and a low activity intensity period. The heart rate monitoring unit (13) detects a declining trend in the heart rate of the exerciser, in the low activity intensity period each time, and monitors whether or not the declining trend of this time is low as compared with a predetermined reference. The activity monitoring unit (14), in a case in which the monitoring by the heart rate monitoring unit is affirmed, monitors whether or not the activity intensity to be detected in the high activity intensity period of a next time is low as compared with activity intensities detected in high activity intensity periods up to a previous time. The notification processing unit (15), in a case in which the monitoring by the activity monitoring unit is affirmed, forecasts an outbreak of disease. With this configuration, the outbreak of disease in an exerciser during an exercise is forecasted with higher accuracy.

公开(公告)号：US20240008761A1

公开(公告)日：2024-01-11

申请号：US18265040

申请日：2021-11-25

Applicant: OSAKA UNIVERSITY

Inventor： Hidetaka KIOKA ,  Yusuke TAKAHASHI ,  Shinichiro FUKUHARA ,  Yasushi SAKATA ,  Norio NONOMURA ,  Seiji TAKASHIMA ,  Shigeyoshi SAITO

IPC: A61B5/055 ,  G01R33/485 ,  A61B5/00

CPC classification number: A61B5/055 ,  G01R33/485 ,  A61B5/4387

Abstract: An evaluation method is performed by an arithmetic circuit and includes obtainment processing (S1), evaluation processing (S2), and presentation processing (S3). The obtainment processing (S1) obtains: image information on a sectional image representing an interested section of an organism including a target section of a testis of the organism generated by use of magnetic resonance of hydrogen atoms; and concentration information on a creatine concentration in the interested section measured by use of magnetic resonance based on chemical exchange saturation transfer. The evaluation processing (S2) generates an evaluation image representing a distribution of evaluation results of a testicular function in the target section based on the concentration information. The presentation processing (S3) presents the sectional image and the evaluation image.

公开(公告)号：US11867610B2

公开(公告)日：2024-01-09

申请号：US18152354

申请日：2023-01-10

Applicant: The University of Tokyo ,  Osaka University

Inventor： Sadao Ota ,  Ryoichi Horisaki ,  Kazuki Hashimoto

IPC: G01J3/00 ,  G01N21/01 ,  G01B11/00 ,  G01N21/64 ,  H03M7/30 ,  G01N21/53 ,  G01N21/59

CPC classification number: G01N21/01 ,  G01B11/00 ,  G01N21/53 ,  G01N21/59 ,  G01N21/64 ,  G01N21/6456 ,  H03M7/3062

Abstract: Any one or both of an optical system with a structured lighting pattern and a structured detecting system having a plurality of regions with different optical characteristics are used. In addition, optical signals from an object to be observed through one or a small number of pixel detectors are detected while changing relative positions between the object to be observed and any one of the optical system and the detecting system, time series signal information of the optical signals are obtained, and an image associated with an object to be observed from the time series signal information is reconstructed.

公开(公告)号：US11863164B2

公开(公告)日：2024-01-02

申请号：US17002419

申请日：2020-08-25

Applicant: Kyoto University ,  Osaka University

Inventor： Keisuke Fujii ,  Makoto Negoro ,  Kosuke Mitarai ,  Masahiro Kitagawa

IPC: G06N10/00 ,  H03K19/195 ,  G06F18/214

CPC classification number: H03K19/195 ,  G06F18/214 ,  G06N10/00

Abstract: The quantum circuit learning device includes a signal input unit that provides a quantum circuit including plural quantum bits with an input signal, a signal acquisition unit that observes states of quantum bits that the quantum circuit includes and acquires an output signal based on the observed states, and an adjustment unit that adjusts a circuit parameter that defines a circuit configuration of the quantum circuit, using an output signal that the signal acquisition unit acquires and a cost function that is set based on a teacher signal corresponding to the output signal.

公开(公告)号：US20230414192A1

公开(公告)日：2023-12-28

申请号：US18463894

申请日：2023-09-08

Applicant: OSAKA UNIVERSITY

Inventor： Hirotada MASUDA ,  Yoshiki SAWA ,  Toru KURATANI

IPC: A61B7/04 ,  A61B5/00 ,  A61B5/02

CPC classification number: A61B7/04 ,  A61B5/7275 ,  A61B5/02028 ,  A61B5/02007 ,  A61B5/726

Abstract: A heart valve abnormality detection device includes a heart sound data acquisition portion 21 configured to acquire heart sound data corresponding to heart sounds, a first processing portion configured to set, based on the heart sound data, a section between a first heart sound and a second heart sound of the heart sounds as a target range and acquire a peak frequency that is a peak value of a frequency in a frequency component of the heart sounds within the target range, and a second processing portion configured to output a detection signal indicating that there is a high probability of severe aortic stenosis in a case where the peak frequency is a peak reference value or greater.

公开(公告)号：US11827578B2

公开(公告)日：2023-11-28

申请号：US17253438

申请日：2019-06-18

Applicant: OSAKA UNIVERSITY

Inventor： Kei Ohkubo

IPC: C07C33/00 ,  C07C51/29 ,  C07B33/00 ,  C07C29/48 ,  C07C45/30 ,  C07C51/16

CPC classification number: C07B33/00 ,  C07C29/48 ,  C07C45/30 ,  C07C51/16 ,  C07C51/29

Abstract: The present invention is intended to provide a method that can produce an oxidation reaction product of a hydrocarbon or a derivative thereof in an aqueous phase using a hydrocarbon or a derivative thereof as a raw material. In order to achieve the above object, the method for producing an oxidation reaction product of a hydrocarbon or a derivative thereof of the present invention includes the step of: irradiating a reaction system with light in a presence of a raw material and a halogen oxide radical to react, wherein the raw material is a hydrocarbon or a derivative thereof, the reaction system is a reaction system containing an aqueous phase, the aqueous phase contains the raw material and the halogen oxide radical, and in the reaction step, the raw material is oxidized to produce an oxidation reaction product of the raw material.

公开(公告)号：US11826131B2

公开(公告)日：2023-11-28

申请号：US16776631

申请日：2020-01-30

Applicant: OSAKA UNIVERSITY

Inventor： Hitomi Nakamura ,  Tadashi Kimura ,  Takayoshi Hosono

IPC: A61B5/0538 ,  A61B5/00 ,  A61B5/053 ,  A61B10/00

CPC classification number: A61B5/0538 ,  A61B5/053 ,  A61B5/4325 ,  A61B5/4331 ,  A61B5/4337 ,  A61B5/6853 ,  A61B5/6875 ,  A61B10/0012 ,  A61B2010/0016

Abstract: A non-invasive and accurate vagina evaluation device and uterine evaluation devices are provided that measure the receptivity (uterine implantation capacity) of the mother's body to a fertilized egg implanting itself into the uterus. A first vagina evaluation device includes: a main body stretchable and expandable after insertion into a vagina, followed by air injection thereinto; four electrodes brought into contact with the vagina wall as the main body expands and stretches; and fixation means configured to fix the interval of arrangement of the electrodes. Second and third uterine evaluation device include: a flexible and rod-shaped main body for insertion into a uterine cavity; and four or two impedance electrodes arranged with a predetermined interval therebetween in an insertion direction of the main body and brought into contact with an endometrium of the uterine cavity to measure a uterine endometrial impedance generated between the endometrium and each of the electrodes.

公开(公告)号：US20230374103A1

公开(公告)日：2023-11-23

申请号：US18027695

申请日：2021-09-27

Applicant: OSAKA UNIVERSITY

Inventor： Munehisa SHIMAMURA ,  Hironori NAKAGAMI ,  Ryuichi MORISHITA

IPC: C07K14/705 ,  A61P11/00 ,  A61P35/00

CPC classification number: C07K14/70575 ,  A61P11/00 ,  A61P35/00 ,  A61K38/00

Abstract: Provided are preventive or therapeutic agents for fibrotic diseases and cancer. A Wnt signaling pathway inhibitor or a preventive and therapeutic agent for fibrotic diseases or cancer, both comprising an oligopeptide consisting of an amino acid sequence containing a DE loop sequence of RANKL protein and a β-strand sequence of RANKL protein placed adjacent to the N-terminal side of the DE loop sequence.