公开(公告)号：US07309946B2

公开(公告)日：2007-12-18

申请号：US10753258

申请日：2004-01-05

Applicant: Ing-Shouh Hwang ,  Shao-Kang Hung ,  Cheng-Shing Tin ,  And De Hu

Inventor： Ing-Shouh Hwang ,  Shao-Kang Hung ,  Cheng-Shing Tin ,  And De Hu

IPC: H01L41/08

CPC classification number: H02N2/023

Abstract: A motion actuator comprises a cylindrical movable shaft and a stage that contains an expansible/contractible device and two clamps. The expansible/contractible device can be controlled to drive the axial motion of the movable shaft, and the two clamps can be controlled to grip/release the shaft. The two clamps and the expansible/contractible device are each controlled by a bimorph structure, which comprises a cut cylindrical piezoelectric tube section in a hole enclosed by a thin wall in the stage. By sequentially activating the three piezoelectric tube sections, axial motions of the movable shaft relative to the stage in small steps are made. Each of the two clamps can be adjusted by a screw, which presses a spring structure that makes contact with the top surface of the movable shaft, so that the clamps can grip the movable shaft firmly when actuated, but not when not actuated. The flat top surface of the movable shaft is designed to inhibit the possible rotation along its axis during its axial motion. The shaft is supported by two lines at the bottom of each of the two clamps to reduce the contact area, which improves the reliability of the motion.

Abstract translation: 运动致动器包括圆柱形可动轴和包含可膨胀/收缩装置和两个夹具的台架。 可以控制可膨胀/收缩装置以驱动可动轴的轴向运动，并且可以控制两个夹具以夹紧/释放轴。 两个夹具和可膨胀/收缩装置各自由双压电晶片结构控制，该双压电晶片结构包括在阶段中由薄壁包围的孔中的切割的圆柱形压电管部分。 通过顺序地激活三个压电管部分，制造可移动轴相对于台阶的小步骤的轴向运动。 两个夹具中的每一个可以通过螺钉调节，该螺钉挤压与可动轴的顶表面接触的弹簧结构，使得夹具可以在致动时牢固地夹紧可动轴，而不是在未致动时夹紧可动轴。 可移动轴的平坦顶面被设计成在其轴向运动期间阻止沿其轴线的可能的旋转。 轴由两个夹具每个底部的两条线支撑，以减小接触面积，从而提高了运动的可靠性。

公开(公告)号：US20070285657A1

公开(公告)日：2007-12-13

申请号：US11423818

申请日：2006-06-13

Applicant: Yuh-Lin WANG ,  Huai-Hsien WANG ,  Chih-Yi LIU ,  Juen-Kai WANG

Inventor： Yuh-Lin WANG ,  Huai-Hsien WANG ,  Chih-Yi LIU ,  Juen-Kai WANG

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658

Abstract: This invention relates to methods of preparing substrates that enhance the Raman signal of analytes in surface-enhanced Raman spectroscopy (SERS). The SERS-active substrate comprises an array of metal nanoparticles at least partially embedded in a template. The substrate's uniform and readily reproducible SERS-active properties with a wide range of analyte concentrations substantially enhance the power and utility of SERS. This invention also provides sensors, as well as Raman instruments, comprising the SERS-active substrates.

Abstract translation: 本发明涉及在表面增强拉曼光谱（SERS）中制备增强分析物拉曼信号的底物的方法。 SERS活性基底包括至少部分地嵌入模板中的金属纳米颗粒阵列。 底物均匀且易于重现的具有广泛分析物浓度的SERS-活性特性显着增强了SERS的功效和效用。 本发明还提供了包括SERS活性基底的传感器以及拉曼仪器。

公开(公告)号：US07282353B2

公开(公告)日：2007-10-16

申请号：US10921741

申请日：2004-08-19

Applicant: Yu-Chan Chao ,  Tzu-Ching Lee

Inventor： Yu-Chan Chao ,  Tzu-Ching Lee

IPC: C12P21/04

CPC classification number: C12N7/00 ,  C07K2319/00 ,  C12N15/86 ,  C12N2710/14122 ,  C12N2710/14143 ,  C12N2720/12022 ,  C12N2770/32122 ,  C12N2810/40 ,  C12N2830/00 ,  C12N2830/60

Abstract: A fusion protein containing a polyhedrin of a virus and a foreign polypeptide sequence. Also disclosed are a recombinant occlusion body containing the fusion protein, an isolated nucleic acid containing a sequence encoding the fusion protein, and a recombinant virus containing the nucleic acid. Within the scope of this invention are related expression vectors, host cells, compositions, and preparation methods.

Abstract translation: 含有病毒多角体蛋白和外来多肽序列的融合蛋白。 还公开了含有融合蛋白的重组闭塞体，含有编码融合蛋白的序列的分离的核酸和含有核酸的重组病毒。 在本发明的范围内是相关的表达载体，宿主细胞，组合物和制备方法。

公开(公告)号：US20070202586A1

公开(公告)日：2007-08-30

申请号：US11362051

申请日：2006-02-24

Applicant: Andrew Wang ,  Kai-Fa Huang

Inventor： Andrew Wang ,  Kai-Fa Huang

IPC: C12N9/88 ,  G06F19/00

CPC classification number: C12N9/104 ,  C07K2299/00 ,  G01N2333/9108 ,  Y02A90/26

Abstract: The invention relates to a crystalline structure of glutaminyl cyclase (QC). The invention also relates to the methods of preparing the crystalline structure of QC and the methods for identifying candidate inhibitors of QC. This invention further provides a structural basis for the rational design or identification of new inhibitors that may be used to treat QC-associated disorders.

Abstract translation: 本发明涉及谷氨酰胺环化酶（QC）的晶体结构。 本发明还涉及制备QC晶体结构的方法以及鉴定QC候选抑制剂的方法。 本发明还提供了可用于治疗QC相关疾病的新型抑制剂的合理设计或鉴定的结构基础。

公开(公告)号：US07242812B2

公开(公告)日：2007-07-10

申请号：US10603620

申请日：2003-06-26

Applicant: Wen-Liang Hwang ,  Jian-Liang Lin

Inventor： Wen-Liang Hwang ,  Jian-Liang Lin

IPC: G06K9/36 ,  G06K9/46

CPC classification number: H04N19/34 ,  H04N19/105 ,  H04N19/136 ,  H04N19/184 ,  H04N19/187 ,  H04N19/61 ,  H04N19/96

Abstract: A novel method for coding and decoding video data and codec thereof are disclosed. The invented method provides an FGS (fine grained scalability) algorithm using bit plane coding technique. While conducting the bit plane encoding, the spatial and temporal dependence between bit planes is used to exploit the redundancy in the bit planes. In the embodiment of this invention, the bit plains are represented by quadtrees and bit plane prediction is made to remove the spatial and temporal redundancy in a video. The scalability of the video data is fine grained since atoms of the motion residuals do not have to be grouped as coding units.

Abstract translation: 公开了一种用于对视频数据及其编解码器进行编码和解码的新方法。 本发明的方法提供了使用位平面编码技术的FGS（细粒度可扩展性）算法。 在进行位平面编码的同时，使用位平面之间的空间和时间依赖性来利用位平面中的冗余。 在本发明的实施例中，位平面由四叉树表示，并且进行位平面预测以消除视频中的空间和时间冗余。 视频数据的可扩展性是细粒度的，因为运动残差的原子不必被分组为编码单元。

公开(公告)号：US07223560B2

公开(公告)日：2007-05-29

申请号：US10775050

申请日：2004-02-09

Applicant: Yu-Chan Chao

Inventor： Yu-Chan Chao

IPC: C12N15/866 ,  C12N15/63 ,  C12P21/00 ,  C12Q1/68 ,  C12Q1/70

CPC classification number: G01N33/502 ,  C12N15/86 ,  C12N2710/14143 ,  G01N33/5008 ,  G01N2500/10

Abstract: A baculovirus that infects a host cell without lyzing the host cell and related protein expression method. Within the scope of this invention are in vitro and in vivo methods for detecting protein folding or a cell lysis activity of a sample. Also within the scope of this invention is a method of screening for a compound for treating a disease associated with misfolding of a protein.

Abstract translation: 感染宿主细胞而不破坏宿主细胞的杆状病毒和相关的蛋白质表达方法。 在本发明的范围内，用于检测样品的蛋白质折叠或细胞裂解活性的体外和体内方法。 本发明的范围也是筛选用于治疗与蛋白质错误折叠相关的疾病的化合物的方法。

公开(公告)号：US20070104729A1

公开(公告)日：2007-05-10

申请号：US11553402

申请日：2006-10-26

Applicant: Yuan-Yuan Wang ,  Kay-Hooi Khoo ,  Shui-Tein Chen ,  Chun-Cheng Lin ,  Chi-Huey Wong ,  Chun-Hung Lin ,  Hong-Sen Chen ,  Yow-Fu Tsai

Inventor： Yuan-Yuan Wang ,  Kay-Hooi Khoo ,  Shui-Tein Chen ,  Chun-Cheng Lin ,  Chi-Huey Wong ,  Chun-Hung Lin ,  Hong-Sen Chen ,  Yow-Fu Tsai

IPC: A61K36/06 ,  A61K36/09

CPC classification number: A61K36/074 ,  A23L33/105

Abstract: The present invention provides medicinally active extracts and fractions, and a method for preparing the same by extracting and fractioning constituents from the tissue of components of Ganoderma lucidum. These active extracts and fractions are useful for inhibiting tumor growth, modulating immune response, and increasing hematopoietic activity.

Abstract translation: 本发明提供药物活性提取物和级分，以及通过从灵芝组分的组织提取和分馏成分的方法制备该提取物和级分。 这些活性提取物和级分可用于抑制肿瘤生长，调节免疫应答和增加造血活性。

公开(公告)号：US20070095407A1

公开(公告)日：2007-05-03

申请号：US11262495

申请日：2005-10-28

Applicant: Peilin Chen ,  Jau-Ye Shiu ,  Chiung-Wen Kuo

Inventor： Peilin Chen ,  Jau-Ye Shiu ,  Chiung-Wen Kuo

IPC: F16K11/20

CPC classification number: G02B26/004 ,  B01L3/502707 ,  B01L3/50273 ,  B01L9/52 ,  B01L13/02 ,  B01L2300/0819 ,  B01L2300/0874 ,  B01L2400/0415 ,  B01L2400/0427 ,  B01L2400/0487 ,  G09G3/3433 ,  Y10T137/87249

Abstract: A microfluidic device that includes one or more microchannels configured to transport fluid, and one or more microchambers configured to receive the fluid, wherein each of the one or more microchannels is coupled in fluid communication to at least one of the one or more microchambers. The microfluidic device also includes a first set of electrodes, each of the electrodes electrically coupled to one of the one or more microchannels, and configured to selectively apply an adjustable voltage to the respective microchannel to cause the fluid in that microchannel to flow. The microfluidic device further includes a second set of electrodes, where each of the electrodes in the second set of electrodes is electrically coupled to corresponding microchambers and configured to apply an adjustable voltage to the corresponding microchambers to direct flowing fluid into those corresponding microchambers from the microchannels to which those corresponding microchambers are coupled.

Abstract translation: 一种微流体装置，其包括构造成输送流体的一个或多个微通道，以及被配置为接收流体的一个或多个微室，其中所述一个或多个微通道中的每一个与所述一个或多个微室中的至少一个流体连通地耦合。 微流体装置还包括第一组电极，每个电极电耦合到一个或多个微通道之一，并且被配置为选择性地将可调电压施加到相应的微通道以使该微通道中的流体流动。 微流体装置还包括第二组电极，其中第二组电极中的每个电极电耦合到对应的微室，并且被配置为向相应的微室施加可调节的电压，以将流动流体引导到来自微通道的相应微室中 那些相应的微室耦合到这些微室。

公开(公告)号：US20060151313A1

公开(公告)日：2006-07-13

申请号：US11035855

申请日：2005-01-13

Applicant: Maw-Kuen Wu ,  Chia-Lin Wang ,  Yang-Chung Liao ,  Nyan-Hwa Tai ,  Fong-Chi Hsu

Inventor： Maw-Kuen Wu ,  Chia-Lin Wang ,  Yang-Chung Liao ,  Nyan-Hwa Tai ,  Fong-Chi Hsu

IPC: C23C14/00

CPC classification number: H01M4/40 ,  C23C14/08 ,  C23C14/3414 ,  H01M4/58 ,  H01M4/5825 ,  H01M4/661

Abstract: Method for preparation of anode film for thin film battery comprises: providing a target material to provide Li ion and Ti ion and a substrate comprising a base layer, a buffer layer and a precious metal current collector layer; sputtering LiMO layer on a said substrate at high temperature in a vacuum chamber and obtaining the anode film for thin film battery of this invention. In this invention, material for the precious metal current collector may be a precious metal such as Ag, Au, Pt etc., the alloy and oxides of these metals. The sputtering temperature may be above 300° C., preferably above 500° C. and most preferably above 650° C. The anode thin film material so prepared may be Li4Ti5O12. This invention also discloses anode film so prepared and thin film battery using such anode film.

Abstract translation: 制备薄膜电池用阳极薄膜的方法包括：提供靶材以提供Li离子和Ti离子，以及包括基底层，缓冲层和贵金属集电体层的基底; 在真空室中在高温下在所述基板上溅射LiMO层，并获得本发明的薄膜电池用阳极膜。 在本发明中，贵金属集电体的材料可以是Ag，Au，Pt等贵金属，这些金属的合金和氧化物。 溅射温度可以高于300℃，优选高于500℃，最优选高于650℃。如此制备的阳极薄膜材料可以是Li 4 Ti 5， 12＆gt; 12＆lt; 12＆gt ;. 本发明还公开了如此制备的阳极膜和使用这种阳极膜的薄膜电池。

公开(公告)号：US07060280B2

公开(公告)日：2006-06-13

申请号：US10459155

申请日：2003-06-11

Applicant: Sho Tone Lee

Inventor： Sho Tone Lee

IPC: A61K39/00 ,  A61K39/12

CPC classification number: C07K14/005 ,  A61K39/00 ,  A61K39/12 ,  A61K2039/53 ,  A61K2039/545 ,  A61K2039/55566 ,  C07H21/04 ,  C07K2319/02 ,  C12N2770/24122 ,  C12N2770/24134 ,  Y02A50/386 ,  Y02A50/39 ,  Y02A50/396

Abstract: A method of inducing an immune response in a subject against a flavivirus. The method involves administering to the subject with a fusion polypeptide including a signal peptide and a part of an envelope protein of the flavivirus, or with an expression vector containing a nucleic acid encoding the fusion polypeptide. Also disclosed are a polypeptide, an expression vector, and vaccines containing the polypeptide or expression vector.

Abstract translation: 诱导受试者针对黄病毒的免疫应答的方法。 该方法包括用包含黄病毒的信号肽和一部分包膜蛋白的融合多肽或与含有编码融合多肽的核酸的表达载体给予受试者。 还公开了多肽，表达载体和含有多肽或表达载体的疫苗。