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公开(公告)号:US20240157100A1
公开(公告)日:2024-05-16
申请号:US18362007
申请日:2023-07-31
Inventor: Myunhee LEE
CPC classification number: A61M25/104 , A61M25/09
Abstract: One embodiment provides a balloon dilatation catheter. The balloon dilation catheter, according to the embodiment, comprises a catheter tube provided to be disposed in a blood vessel, a balloon connected to the catheter tube and dilatated by fluid injection, a guide tube disposed along the catheter tube in the balloon and one or more bypass tubes located inside the balloon.
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公开(公告)号:US20240135530A1
公开(公告)日:2024-04-25
申请号:US18209389
申请日:2023-06-12
Inventor: Namkug KIM , Keewon SHIN , Dae-Won KIM
CPC classification number: G06T7/0012 , G06T7/62 , G06T2207/20081 , G06T2207/30101 , G06T2207/30172
Abstract: An apparatus for analyzing a blood vessel includes a processor configured to detect a blood vessel area corresponding to the blood vessel and a stenosis area corresponding to a stenosed portion of the blood vessel, based on a machine learning model, from a blood vessel image, determine a partial area of the blood vessel area to be a comparison area for the stenosis area, based on a length of the stenosis area, and calculate a stenosis score indicating a degree of stenosis of a blood vessel of the stenosis area compared to a blood vessel of the comparison area.
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公开(公告)号:US20240118164A1
公开(公告)日:2024-04-11
申请号:US18377499
申请日:2023-10-06
Inventor: Hosik Hwang
CPC classification number: G01M11/0257 , A61B90/06 , A61F2/16
Abstract: Disclosed is a portable model eye apparatus for intraocular lens evaluation that enables more accurate comparison of intraocular lenses by capturing the same image and situation for different intraocular lenses. A portable model eye apparatus for intraocular lens evaluation according to an aspect of the present invention may include a beam splitter configured to emit an incident light source in two directions at right angles to each other; a pair of corneal modules including a first corneal module and a second corneal module disposed in a first emission direction and a second emission direction of a light source, respectively; a pair of intraocular lens modules including a first intraocular lens module disposed behind the first corneal module along the first emission direction, and a second intraocular lens module disposed behind the second corneal module along the second emission direction; and a pair of camera modules disposed behind the pair of intraocular lens modules, respectively, to obtain images emitted.
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公开(公告)号:US11903821B2
公开(公告)日:2024-02-20
申请号:US17274684
申请日:2018-12-19
Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , Hyung Gu Kwon
Inventor: Hyung Gu Kwon , Dong Jin Chang , Young Jung Roh , Jae Hyung Han
CPC classification number: A61F2/1664 , A61F2/167 , A61F2/1662 , A61F9/007 , A61F9/00727 , A61F9/00781 , A61F2002/169053
Abstract: Provided is an intraocular lens exchanger for moving a foldable intraocular lens (IOL), the intraocular lens exchanger including: an outer tube having a first passage formed in a forward/rearward direction; an inner tube disposed to be movable along the first passage and having a second passage formed in the forward/rearward direction; and a variable tube extending from a front end of the inner tube to form a variable passage connected to the second passage, in which the variable tube has an extension part having a width that increases forward in an unconstrained state in which the variable tube is not positioned in the first passage, and the extension part is provided to be elastically deformed when the unconstrained state changes to a constrained state in which at least a part of the extension part is received in the first passage.
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公开(公告)号:US20240025976A1
公开(公告)日:2024-01-25
申请号:US18265074
申请日:2021-11-29
Inventor: Won Sang PARK , Jung Hwan YOON
IPC: C07K16/18 , C12N15/63 , G01N33/574
CPC classification number: C07K16/18 , C12N15/63 , G01N33/57446 , C07K2317/565 , C07K2317/567 , C07K2317/14
Abstract: The present invention relates to a novel antibody specifically binding to a specific epitope of GKN1 (gastrokine 1) protein, and a gastric cancer diagnostic use thereof. An antibody specific to GKN1 according to the present invention specifically binds to a new epitope, and can be used to confirm the level of GKN1 protein in serum and thereby detect (diagnose) gastric cancer with 100% sensitivity and specificity. Thus, the antibody can be useful for screening and diagnosing gastric cancer.
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公开(公告)号:US20240009037A1
公开(公告)日:2024-01-11
申请号:US18205728
申请日:2023-06-05
Inventor: Ji Youn SIM , Dong Jin CHANG
CPC classification number: A61F13/0246 , A61M27/00 , A61F2013/00412
Abstract: A plaster for fixing a drainage tube is provided, which fixes the drainage tube that is inserted into a patient's body and discharges liquid inside the patient's body to the outside of the patient's body. The plaster includes a plurality of support pads attached to the patient's body to be spaced apart from each other, each of the plurality of support pads having a certain thickness; a support band fixed to respective upper surfaces of the support pads to cover the skin; and a plurality of holders detachably coupled to an upper surface of the support band to hold and fix the drainage tube. The plaster for fixing a drainage tube maintains a stable fixation state by blocking longitudinal movement of the drainage tube as well as lifting of the drainage tube, and protects the skin from a 3-way valve to prevent pain even when the skin is pressed.
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公开(公告)号:US20240000961A1
公开(公告)日:2024-01-04
申请号:US18035894
申请日:2021-11-11
Inventor: Kun NA , Da Hye KIM , Min Ji AHN , Na Eun PARK
CPC classification number: A61K47/6851 , A61K47/60 , A61K41/0071 , A61K47/6889 , A61P35/00
Abstract: The present invention relates to a conjugate including an antibody for treating cancer, a linker, and a block copolymer including PEO and PPO, and a conjugate further including a low molecular weight compound. The conjugate has excellent cancer cell targeting ability and can efficiently increase cancer cells by increasing the half-life of the antibody, and thus can be effectively used for treating cancer.
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公开(公告)号:US20230405051A1
公开(公告)日:2023-12-21
申请号:US18250087
申请日:2021-10-22
Inventor: Sung Won KIM , Seung Ki KWOK , Jaeseon LEE , Se Gwang JANG , Jung Yeon LIM , Sun Hwa PARK , Jung Ho CHUN
Abstract: The present invention relates to a pharmaceutical composition for prevention or treatment of rheumatoid arthritis, the composition comprising, as an active ingredient, human nasal inferior turbinate-derived stem cells in which the expression of specific genes is increased or decreased. The human nasal inferior turbinate-derived stem cells exhibiting a therapeutic effect on arthritis were identified to specifically have an increased expression level of HAS2, CXCL1, or KRTAP1-5 gene or a decreased expression level of GSTT2B or C4B gene. Thus, by taking advantage of this feature, only stem cells that have a therapeutic effect on arthritis can be selected for use in treating rheumatoid arthritis, with the expectation of enhancing the therapeutic effect. Furthermore, it is expected that a method for selecting stem cells useful as a therapeutic agent for rheumatoid arthritis can be provided.
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公开(公告)号:US20230218678A1
公开(公告)日:2023-07-13
申请号:US17912246
申请日:2021-03-18
Inventor: Tai Gyu KIM , Su Eon KIM
Abstract: The present invention relates to a cord blood plasma-derived exosome or a mimetic thereof and a pharmaceutical use thereof. More particularly, the present invention provides the use of a human cord blood plasma-derived exosome or an exosome mimetic that mimics the proteomic profile of the cord blood plasma-derived exosome for the improvement, prevention or treatment of various autoimmune diseases or wound healing.
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公开(公告)号:US11690737B2
公开(公告)日:2023-07-04
申请号:US16328094
申请日:2016-09-05
Inventor: Myung-Gyu Choi , Seok-Hyun Yun , Bo-In Lee , Jae Myung Park , Ehsan Kamrani , Ali Kemal Yetisen
IPC: A61F2/82 , A61F7/12 , A61B5/07 , A61B18/00 , A61F2/48 , A61F7/00 , A61B18/10 , A61B18/08 , A61N5/06 , A61B5/00 , A61N1/372 , A61N1/378 , A61B5/1473
CPC classification number: A61F2/82 , A61B5/076 , A61B5/6862 , A61B18/082 , A61B18/10 , A61F7/12 , A61N1/3787 , A61N1/37223 , A61N5/0601 , A61N5/062 , A61N5/0603 , A61B5/1473 , A61B2018/00577 , A61F2/482 , A61F2007/0094 , A61F2007/126 , A61F2250/0001 , A61N2005/0602 , A61N2005/0651
Abstract: A stent device including a stent coated with a photosensitizer, the stent including a pair of electrodes; and a circuit fixed to the stent, the circuit including a light emitting diode, a power receiving means for wirelessly receiving power from the outside, and converting the power to electric power; a second communicating means for receiving a control command from the outside; and a second control means for applying, based on the control command, the electric power to the electrodes causing an electric current to flow through the stent between the electrodes, the flow causing heating of the stent, and for controlling a temperature of the stent to provide hyperthermia therapy to a tumor, the second control means further for applying, based on the control command, the electric power to the light emitting diode to emit a predetermined wavelength of light to the photosensitizer to provide photodynamic therapy to the tumor.
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