Staged Preconcentration and Parallel Column Gas Chromatography

    公开(公告)号:US20180172647A1

    公开(公告)日:2018-06-21

    申请号:US15379963

    申请日:2016-12-15

    IPC分类号: G01N30/16 B01D53/04

    摘要: We disclose a device that both extracts and preconcentrates volatile analytes in preparation for separation by gas chromatography. The device includes a conduit that may include two, and sometimes three, separate sections that are connected end-to-end, but which may be separated prior to inserting into a gas chromatograph port. The inner surface of each section is coated with one or more sorbents, each with a different affinity for volatile analytes. The sorbents may be positioned along the sections of the column in order of relative affinity for volatile analytes. The sections may be heated independently of each other to release the volatile analytes from the sorbents more quickly. This device reduces the time and the temperature required to achieve separation by gas chromatography. The device may be used to perform gas chromatography in ubiquitous environments such as the home or a mobile situation.

    Pharmaceutical Dispensing Method in an Unattended Medical Kiosk

    公开(公告)号:US20180113995A1

    公开(公告)日:2018-04-26

    申请号:US15333834

    申请日:2016-10-25

    IPC分类号: G06F19/00 G06F21/32

    摘要: A pharmaceutical dispensing method using an unattended medical kiosk is disclosed. The pharmaceutical dispensing method securely dispenses medication to users, and provides a format for dispensing that can be easily localized, such as in the form of an unattended medical kiosk while maintaining security, privacy, and verified user identification. In some embodiments the pharmaceutical dispensing method relies on medical testing in the kiosk in order to verify user identification before dispensing medication. In an embodiment a user payment bypass may be utilized in cases of high medical risk allowing the user to get life-saving medication quickly, and in another embodiment a method of remote prescription approval is provided. Further varieties and embodiments of pharmaceutical dispensing using an unattended medical kiosk are disclosed.

    Flushable test strip
    76.
    发明授权

    公开(公告)号:US10191044B2

    公开(公告)日:2019-01-29

    申请号:US15398052

    申请日:2017-01-04

    IPC分类号: G01N33/543

    摘要: We disclose a novel diagnostic test strip which may be used to conduct biochemical assays for analytes in liquid samples. The disclosed test strip may be loaded with much smaller volumes of sample than traditional test strips. The disclosed test strip may be loaded with a precision dispenser instead of submersing the test strip into a larger volume of liquid sample. In addition, the disclosed test strip dissolves in aqueous fluid so it may be flushed into the sewer system. Consequently, it is not necessary to dispose of the disclosed test strip in biological waste containers.

    Ion modulator for characterizing larger biomolecules in a differential mobility spectrometer

    公开(公告)号:US10163614B1

    公开(公告)日:2018-12-25

    申请号:US15632636

    申请日:2017-06-26

    摘要: The tandem differential mobility spectrometer (DMS)-ion modulator instrument provides improved resolution relative to traditional DMS for molecules with larger masses. The instrument includes an ion-bunching electrode with an AC field synchronized to the transit time of the ion flow which is positioned downstream of a DMS. The ion bunching electrode produces a mobility-dependent modulation of the ion current. The ratio of AC to DC current provides a measure of the mobility of a large ion, even if it has little differential mobility, thereby extending the useful range of mobility characterization of a DMS system. The instrument is more compact than a larger traditional ion mobility spectrometer and does not require high voltages or high frequencies. Modulation before DMS separation or between tandem DMS separations produces a variable range of analyte and reactant ion densities as well as spatially separating negative and positive ions to reduce ion recombination.