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公开(公告)号:US10258261B2
公开(公告)日:2019-04-16
申请号:US15400231
申请日:2017-01-06
申请人: David R. Hall , Dan Allen , Terrece Pearman
发明人: David R. Hall , Dan Allen , Terrece Pearman
IPC分类号: G01N31/22 , A61B5/145 , A61B5/0205 , A61B5/00 , A61B7/02 , A61B10/00 , A47K17/02 , E03D11/13 , G01G19/52 , A61B5/0402 , A61B5/021 , A61B5/053 , A61B8/00 , A61B5/1455 , A61B7/04
摘要: We disclose a system which may be used to analyze data collected from a customized test strip. The customized test strip may include a set of reaction pads which are selected to address the medical needs of a specific user. The system may include a data analysis platform which analyzes the data and proposes a second customized test strip. The second test strip may comprise of a set of reaction pads that the data analysis platform selects for the user based on the analysis of the first customized test strip. The data analysis platform may propose that additional diagnostic metrics be collected from the user to assist in diagnosis. The customized test strips and the additional diagnostic metrics may be within a medical toilet.
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公开(公告)号:US20180172647A1
公开(公告)日:2018-06-21
申请号:US15379963
申请日:2016-12-15
申请人: David R. Hall , Dan Allen , Steven Butala
发明人: David R. Hall , Dan Allen , Steven Butala
CPC分类号: G01N30/14 , B01D53/0438 , B01D2259/40088 , G01N1/2214 , G01N30/08 , G01N30/16 , G01N2030/025 , G01N2030/143
摘要: We disclose a device that both extracts and preconcentrates volatile analytes in preparation for separation by gas chromatography. The device includes a conduit that may include two, and sometimes three, separate sections that are connected end-to-end, but which may be separated prior to inserting into a gas chromatograph port. The inner surface of each section is coated with one or more sorbents, each with a different affinity for volatile analytes. The sorbents may be positioned along the sections of the column in order of relative affinity for volatile analytes. The sections may be heated independently of each other to release the volatile analytes from the sorbents more quickly. This device reduces the time and the temperature required to achieve separation by gas chromatography. The device may be used to perform gas chromatography in ubiquitous environments such as the home or a mobile situation.
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公开(公告)号:US20180113995A1
公开(公告)日:2018-04-26
申请号:US15333834
申请日:2016-10-25
申请人: David R. Hall , Dan Allen , Cameron Price
发明人: David R. Hall , Dan Allen , Cameron Price
CPC分类号: G16H10/60 , G06F21/31 , G06F21/6245 , G16H20/13
摘要: A pharmaceutical dispensing method using an unattended medical kiosk is disclosed. The pharmaceutical dispensing method securely dispenses medication to users, and provides a format for dispensing that can be easily localized, such as in the form of an unattended medical kiosk while maintaining security, privacy, and verified user identification. In some embodiments the pharmaceutical dispensing method relies on medical testing in the kiosk in order to verify user identification before dispensing medication. In an embodiment a user payment bypass may be utilized in cases of high medical risk allowing the user to get life-saving medication quickly, and in another embodiment a method of remote prescription approval is provided. Further varieties and embodiments of pharmaceutical dispensing using an unattended medical kiosk are disclosed.
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公开(公告)号:US10444144B2
公开(公告)日:2019-10-15
申请号:US15493433
申请日:2017-04-21
申请人: David R. Hall , Dan Allen , Daniel Hendricks , Andrew Nguyen , Conrad Rosenbrock , Travis Niederhauser , Joe Fox , Terrece Pearman , Steven J. M. Butala
发明人: David R. Hall , Dan Allen , Daniel Hendricks , Andrew Nguyen , Conrad Rosenbrock , Travis Niederhauser , Joe Fox , Terrece Pearman , Steven J. M. Butala
IPC分类号: G01N21/359 , A61B10/00 , G01N33/15 , A61B5/145 , G01N30/02
摘要: We disclose a method of tagging nutritional or drug compositions using chemical entities which are known to be safely consumed and which are detectable using known techniques, including near IR spectroscopy. The chemical entities used as tags may be detected in easily obtainable biological samples, including urine and feces. The biological sample may be deposited into a medical toilet which may analyze the biological sample using an analytical device associated with the medical toilet. The tag may be identified and quantified to then identify and quantify the nutritional or drug composition the subject consumed along with the tag. This system may be used to track the source of a food or drug, confirm compliance to a prescribed diet or drug treatment, confirm drug consumption in clinical trials, identify the source of contaminated food, and identify the food substances used to produce food products.
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公开(公告)号:US10209264B2
公开(公告)日:2019-02-19
申请号:US15496407
申请日:2017-04-25
申请人: David R. Hall , Dan Allen , Conrad Rosenbrock , Daniel Hendricks , Andrew Nguyen , Steven J. M. Butala , Travis Niederhauser , Terrece Pearman , Joe Fox
发明人: David R. Hall , Dan Allen , Conrad Rosenbrock , Daniel Hendricks , Andrew Nguyen , Steven J. M. Butala , Travis Niederhauser , Terrece Pearman , Joe Fox
IPC分类号: G01N33/94 , G01N33/493 , G01N33/15 , A61B5/15 , A61G10/00 , A47K17/00 , A61B10/00 , G01N33/58
摘要: We disclose a method of using taggants to assess how and to what extent a drug in a drug composition that a user has consumed has decayed in response to storage conditions and time. The taggants may decay in response to environmental conditions which cause different drugs to lose their efficacy. These environmental conditions may include light, temperature, oxidation, moisture, and age. The taggants may be detected in biological samples, including urine and feces. By identifying the taggants, the drug composition and other information relating to the drug may be identified. Additionally, quantification of the different taggants may be used to determine whether the drug in the drug composition has been exposed to environmental conditions which may reduce its efficacy.
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公开(公告)号:US10191044B2
公开(公告)日:2019-01-29
申请号:US15398052
申请日:2017-01-04
申请人: David R. Hall , Dan Allen
发明人: David R. Hall , Dan Allen
IPC分类号: G01N33/543
摘要: We disclose a novel diagnostic test strip which may be used to conduct biochemical assays for analytes in liquid samples. The disclosed test strip may be loaded with much smaller volumes of sample than traditional test strips. The disclosed test strip may be loaded with a precision dispenser instead of submersing the test strip into a larger volume of liquid sample. In addition, the disclosed test strip dissolves in aqueous fluid so it may be flushed into the sewer system. Consequently, it is not necessary to dispose of the disclosed test strip in biological waste containers.
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公开(公告)号:US10163614B1
公开(公告)日:2018-12-25
申请号:US15632636
申请日:2017-06-26
申请人: David R. Hall , Dan Allen , Joe Fox
发明人: David R. Hall , Dan Allen , Joe Fox
摘要: The tandem differential mobility spectrometer (DMS)-ion modulator instrument provides improved resolution relative to traditional DMS for molecules with larger masses. The instrument includes an ion-bunching electrode with an AC field synchronized to the transit time of the ion flow which is positioned downstream of a DMS. The ion bunching electrode produces a mobility-dependent modulation of the ion current. The ratio of AC to DC current provides a measure of the mobility of a large ion, even if it has little differential mobility, thereby extending the useful range of mobility characterization of a DMS system. The instrument is more compact than a larger traditional ion mobility spectrometer and does not require high voltages or high frequencies. Modulation before DMS separation or between tandem DMS separations produces a variable range of analyte and reactant ion densities as well as spatially separating negative and positive ions to reduce ion recombination.
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公开(公告)号:US20180321218A1
公开(公告)日:2018-11-08
申请号:US15589403
申请日:2017-05-08
申请人: David R. Hall , Dan Allen , Conrad Rosenbrock , Daniel Hendricks , Andrew Nguyen , Steven J.M. Butala , Travis Niederhauser , Terrece Pearman , Joe Fox
发明人: David R. Hall , Dan Allen , Conrad Rosenbrock , Daniel Hendricks , Andrew Nguyen , Steven J.M. Butala , Travis Niederhauser , Terrece Pearman , Joe Fox
IPC分类号: G01N33/493 , G01N33/53 , G01N33/487 , G01N33/543 , G01N33/542 , G01N27/327 , G01N21/64 , G01N21/78 , A61B5/00 , A61B5/20
CPC分类号: G01N33/493 , A61B5/0071 , A61B5/207 , G01N21/6428 , G01N21/78 , G01N27/3276 , G01N33/48792 , G01N33/5308 , G01N33/542 , G01N33/5438 , G01N2021/6417 , G01N2021/6432 , G01N2021/6439
摘要: We disclose an in-toilet urinalysis system which includes a system for collection urine and for analysis of urine components using aptamer technology. Urine collection system may dispense urine into cuvettes, channels, or other containers that include aptamers. The aptamers may detect target molecules in urine. The aptamers may measure urine analytes, detect excreted drugs or drug metabolites, or disease markers. Upon binding to the target molecule, the aptamers may produce a signal which a sensor in the toilet may detect. In some embodiments, the signal may be electrochemical, fluorescent, or colorimetric. The measurements obtained from analysis of the urine may be used to assess a user's health or diagnose disease. In some embodiments, the measurements are stored in a controller which may transmit the measurements to a healthcare provider for assessment.
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公开(公告)号:US20180306824A1
公开(公告)日:2018-10-25
申请号:US15493433
申请日:2017-04-21
申请人: David R. Hall , Dan Allen , Daniel Hendricks , Andrew Nguyen , Conrad Rosenbrock , Travis Niederhauser , Joe Fox , Terrece Pearman , Steven J.M. Butala
发明人: David R. Hall , Dan Allen , Daniel Hendricks , Andrew Nguyen , Conrad Rosenbrock , Travis Niederhauser , Joe Fox , Terrece Pearman , Steven J.M. Butala
IPC分类号: G01N33/94 , A61B5/15 , A61B10/00 , G01N21/359
CPC分类号: G01N21/359 , A61B5/145 , A61B10/0038 , A61B10/0051 , A61B10/007 , A61B2010/0009 , A61B2010/0061 , A61B2010/0077 , A61B2010/0087 , G01N30/02 , G01N33/15 , G01N2458/15
摘要: We disclose a method of tagging nutritional or drug compositions using chemical entities which are known to be safely consumed and which are detectable using known techniques, including near IR spectroscopy. The chemical entities used as tags may be detected in easily obtainable biological samples, including urine and feces. The biological sample may be deposited into a medical toilet which may analyze the biological sample using an analytical device associated with the medical toilet. The tag may be identified and quantified to then identify and quantify the nutritional or drug composition the subject consumed along with the tag. This system may be used to track the source of a food or drug, confirm compliance to a prescribed diet or drug treatment, confirm drug consumption in clinical trials, identify the source of contaminated food, and identify the food substances used to produce food products.
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公开(公告)号:US20180206772A1
公开(公告)日:2018-07-26
申请号:US15414197
申请日:2017-01-24
申请人: David R. Hall , Dan Allen
发明人: David R. Hall , Dan Allen
IPC分类号: A61B5/20 , G01N33/493 , A61B5/145 , A61B10/00 , A61B5/1477 , A61B5/1455
CPC分类号: A61B5/201 , A61B5/14507 , A61B5/1455 , A61B5/1477 , A61B5/207 , A61B10/007 , A61B2562/0271 , A61B2562/0295 , G01N33/493
摘要: We disclose an in-toilet urinalysis system which includes a system for collection urine and applying the urine to a urine test strip. The system may include an orifice within a toilet bowl which leads into a channel. The channel may be connected to a capillary which has an orifice at each end. Urine may pass through the orifice, into the channel, then may be moved by capillary action through the capillary. A urine test strip dispenser may move reaction pads on a urine test strip to the distal end of the capillary to load the reaction pads with urine. The reaction pads may absorb the urine from the most distal orifice of the capillary. A measurable chemical reaction may occur in the reaction pads in response to urine analytes.
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