公开(公告)号：US12076235B2

公开(公告)日：2024-09-03

申请号：US17363241

申请日：2021-06-30

Applicant: Edwards Lifesciences Corporation

Inventor： Diana Nguyen-Thien-Nhon ,  Timothy A. Geiser ,  Larry L. Wood ,  Dinesh L. Sirimanne ,  Son V. Nguyen ,  Tamir S. Levi ,  Nikolay Gurovich ,  Michael Bukin

IPC: A61F2/07 ,  A61F2/24

CPC classification number: A61F2/2418 ,  A61F2002/072 ,  A61F2210/0076 ,  A61F2220/0075 ,  A61F2230/0026 ,  A61F2230/0093 ,  A61F2250/0003 ,  A61F2250/0039 ,  A61F2250/0069

Abstract: A prosthetic heart valve includes a frame, a valvular structure, and a skirt. The frame is movable between collapsed and expanded configurations and includes struts disposed between inflow and outflow ends, apices disposed at the inflow end formed by intersections of two or more struts, and junctions disposed between the apices and the outflow end and formed by intersections of two or more struts. The apices are circumferentially offset from the junctions. The valvular structure is positioned within and secured to the frame. The skirt is secured to the frame and includes a first edge portion and a second edge portion. The first edge portion is secured to the frame at the apices. The second edge portion is secured to the frame at the junctions. The skirt is configured to retract inwardly between the apices when the frame is moved from the radially expanded configuration to the radially collapsed configuration.

公开(公告)号：US20240207046A1

公开(公告)日：2024-06-27

申请号：US18522551

申请日：2023-11-29

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Nikolai Gurovich ,  Michael Bukin ,  Anatoly Dvorsky ,  Eran Grosu ,  Noam Nir ,  Joseph Mordechai Leichner ,  Elena Sherman ,  Guillermo W. Moratorio

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2220/0008 ,  A61F2220/0025

Abstract: A prosthetic heart valve comprises a radially expandable frame comprising an outflow end and an inflow end, and a plurality of valve leaflets disposed within and coupled to the frame. Each leaflet comprises a main body having an outflow edge portion and an inflow edge portion, wherein the leaflets are configured to move between an open state and a closed state in which the outflow edge portions coapt with each other and block the flow of blood through the frame from the outlet end to the inlet end, wherein the inflow edge portion of each leaflet includes a movable portion that can move radially inwardly when the leaflets move to the closed state to assist with the coaptation of the outflow edge portions of the leaflets and radially outwardly when the leaflets move to the open state.

公开(公告)号：US20240180696A1

公开(公告)日：2024-06-06

申请号：US18402589

申请日：2024-01-02

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Michael Bukin ,  Nikolai Gurovich ,  Elena Sherman ,  Anatoly Dvorsky ,  Eran Grosu

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/243 ,  A61F2/2436

Abstract: A prosthetic valve includes an annular frame and a valvular structure mounted within the annular frame. The valvular structure comprises a plurality of leaflets defining a plurality of commissures coupled to the annular frame. Each leaflet includes a leaflet free edge that is offset in a downstream direction from the commissures by side edges that are not attached to the frame. A material portion of the leaflet disposed between the side edges contributes a material slack that extends a radial reach of the leaflet free edge for coaptation. The prosthetic valve can be releasably coupled to a delivery device to form a delivery apparatus. The prosthetic valve can be delivered to a selected implantation site by the delivery apparatus and released at the implantation site by a handle of the delivery device.

公开(公告)号：US20240156594A1

公开(公告)日：2024-05-16

申请号：US18419840

申请日：2024-01-23

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Tomer Saar ,  Michael Bukin ,  Elena Sherman ,  Alexander Barash ,  Yana Mayatskaya

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2412 ,  A61F2210/0014 ,  A61F2220/0075

Abstract: A prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration can include an annular frame including a plurality of angled strut members, a plurality of leaflets disposed within the frame and secured to the frame, a valve component sutured to a leaflet of the plurality of leaflets and extending along an edge portion of the leaflet adjacent at least one strut member of the plurality of strut members, and a suture threaded around the valve component and extending generally in a direction along a longitudinal axis of the at least one strut member to secure the valve component and the leaflet to the at least one strut member.

公开(公告)号：US20240058129A1

公开(公告)日：2024-02-22

申请号：US18112455

申请日：2023-02-21

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Shaun Fetherston ,  Alexander H. Siemons ,  Blake W. Axelrod ,  Gil Senesh ,  Tomer Saar ,  Oren Cohen ,  Elazar Levi Schwarcz ,  Tamir S. Levi ,  Michael Bukin ,  Michael R. Bialas ,  Timothy A. Geiser ,  Sudarsan Pranatharthikaran ,  Carla Susana Cerqueira

IPC: A61F2/24 ,  A61B8/00 ,  A61B8/08

CPC classification number: A61F2/2496 ,  A61B8/445 ,  A61B8/0883 ,  A61F2/2433 ,  A61B2090/064

Abstract: A medical balloon sensing assembly constituted of: a handle; a first catheter extending distally from the handle; an inflatable medical balloon, the inflatable medical balloon secured by the first catheter; at least one sensor position member; and at least one sensor secured to the at least one sensor position member, wherein the at least one sensor position member is arranged to contact an outer face of the inflatable medical balloon.

公开(公告)号：US20230270541A1

公开(公告)日：2023-08-31

申请号：US18195288

申请日：2023-05-09

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Tamir S. Levi ,  Shahram Zamani ,  Michael Bukin ,  Ziv Yohanan ,  Noam Nir ,  Tyler Dale O'Dell ,  Elena Sherman

IPC: A61F2/24

CPC classification number: A61F2/2415 ,  A61F2/2418 ,  A61F2220/0075

Abstract: A method of assembling a valvular structure can include folding an upper tab of a first leaflet onto a lower tab of the first leaflet, disposing a first end of a reinforcing member on the upper tab, disposing a commissure member adjacent the lower tab, and coupling the first end of the reinforcing member, the tabs of the first leaflet, and the commissure member to one another. The method can further include folding an upper tab of a second leaflet onto a lower tab of the second leaflet, disposing the second leaflet adjacent the first leaflet such that the commissure member is positioned between the lower tabs, disposing a second end of the reinforcing member on the upper tab of the second leaflet, and coupling the reinforcing member, the upper and lower tabs of the second leaflet, and the commissure member to one another to form a commissure.

公开(公告)号：US20230255762A1

公开(公告)日：2023-08-17

申请号：US18306740

申请日：2023-04-25

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Shahram Zamani ,  Michael Bukin ,  Sandip Vasant Pawar

IPC: A61F2/24

CPC classification number: A61F2/243 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2220/0075 ,  A61F2/2463 ,  A61F2/2436 ,  A61F2/2439 ,  A61F2250/0069 ,  A61F2250/0028

Abstract: A sealing member for a prosthetic heart valve includes an annular fabric body having a first circumferential portion and a second circumferential portion. The first circumferential portion extends circumferentially around the annular fabric body and is resiliently stretchable in a direction along the longitudinal axis of the annular fabric body between an expanded configuration of the prosthetic heart valve and a collapsed configuration of the prosthetic heart valve. The second circumferential portion extends around the annular fabric body and is circumferentially offset from the first circumferential portion, the second circumferential portion being resiliently stretchable in a circumferential direction between the collapsed configuration of the prosthetic heart valve and the expanded configuration of the prosthetic heart valve.

公开(公告)号：US20230190462A1

公开(公告)日：2023-06-22

申请号：US17892654

申请日：2022-08-22

Applicant: Edwards Lifesciences Corporation

Inventor： Noam Nir ,  Eran Goldberg ,  Michael Bukin

IPC: A61F2/24

CPC classification number: A61F2/243 ,  A61F2/2418

Abstract: An implantable prosthetic device can include a hybrid frame movable between a radially compressed configuration and a radially expanded configuration. The hybrid frame can include a mechanically-expandable first sub-frame comprising a plurality of struts pivotably coupled to one another, and a self-expanding second sub-frame coupled to the first sub-frame. When the hybrid frame is in the expanded configuration, the second sub-frame can be configured to resist radial compression of the frame.

公开(公告)号：US20230190459A1

公开(公告)日：2023-06-22

申请号：US18108259

申请日：2023-02-10

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Noam Nir ,  Tamir S. Levi ,  Ziv Yohanan ,  Michael Bukin ,  Elena Sherman ,  Yana Mayatskaya

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/243 ,  A61F2220/0075

Abstract: A prosthetic valve includes a radially expandable and compressible annular frame and a valvular structure. The frame includes a first strut and an adjacent second strut that overlap at a pivot joint. Radial expansion or compression of the frame causes the first strut to pivot relative to the second strut at the pivot joint. The valvular structure includes first and second leaflets attached to the first and second struts with a suture. The first and second struts define four strut segments connected by the pivot joint. The suture comprises three interconnected locking knots that are respectively attached to three of the four strut segments.

公开(公告)号：US20230165678A1

公开(公告)日：2023-06-01

申请号：US18096728

申请日：2023-01-13

Applicant: Edwards Lifesciences Corporation

Inventor： Noam Nir ,  Michael Bukin

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2220/0025 ,  A61F2250/0012

Abstract: The present invention relates to implantable prosthetic devices, such as prosthetic heart valves with mechanisms for adjusting the tension of leaflets mounted therein, and to methods, adjustment assemblies and delivery assemblies for, and including, such devices.