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公开(公告)号：US20050042667A1
公开(公告)日：2005-02-24
申请号：US10935098
申请日：2004-09-08
申请人： David LaFleur , Daniel Soppet , Henrik Olsen , Steven Ruben , Jian Ni , Craig Rosen , Laurie Brewer , Roxanne Duan , Reinhard Ebner
发明人： David LaFleur , Daniel Soppet , Henrik Olsen , Steven Ruben , Jian Ni , Craig Rosen , Laurie Brewer , Roxanne Duan , Reinhard Ebner
IPC分类号： C12N15/09 , A61K31/711 , A61K38/00 , A61K39/395 , A61K48/00 , A61P5/00 , A61P7/00 , A61P11/06 , A61P19/02 , A61P29/00 , A61P31/18 , A61P35/00 , A61P35/02 , A61P37/00 , C07K14/435 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/21 , C12N5/10 , C12Q1/68 , C07H21/04 , C12N9/00
摘要： The present invention relates to 36 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
摘要翻译： 本发明涉及36种新型人分泌蛋白和含有编码这种蛋白质的基因的编码区的分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。
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公开(公告)号：US20050032168A1
公开(公告)日：2005-02-10
申请号：US10896972
申请日：2004-07-23
申请人： Craig Rosen , George Komatsoulis , Kevin Baker , Charles Birse , Daniel Soppet , Henrik Olsen , Paul Moore , Ping Wei , Reinhard Ebner , D. Duan , Yanggu Shi , Gil Choi , Michele Fiscella , Jian Ni , Steven Ruben , Steven Barash
发明人： Craig Rosen , George Komatsoulis , Kevin Baker , Charles Birse , Daniel Soppet , Henrik Olsen , Paul Moore , Ping Wei , Reinhard Ebner , D. Duan , Yanggu Shi , Gil Choi , Michele Fiscella , Jian Ni , Steven Ruben , Steven Barash
IPC分类号： C12N15/09 , A61K31/00 , A61K31/7088 , A61K31/713 , A61K38/00 , A61K38/16 , A61K38/43 , A61K38/51 , A61K39/395 , A61K48/00 , A61P1/00 , A61P9/00 , A61P15/00 , A61P21/00 , A61P25/00 , A61P35/00 , A61P43/00 , C07H21/04 , C07K14/47 , C07K14/705 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N9/64 , C12N9/88 , C12N15/12 , C12N15/52 , C12N15/60 , C12P21/02 , C12Q1/02 , C12Q1/68 , G01N33/53 , G01N33/68
CPC分类号： C07K14/47 , A01K2217/05 , A61K38/00 , A61K48/00 , A61K2039/505 , C07K14/705 , C07K16/18 , C07K2319/30 , C12N9/6424 , C12N2799/026 , C12Q1/6883 , G01N2500/00
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20060099575A9
公开(公告)日：2006-05-11
申请号：US09949925
申请日：2001-09-12
申请人： Steven Ruben , Ann Ferrie , Craig Rosen , Kimberly Florence , Kenneth Carter , Daniel Soppet , Guo-Liang Yu , Charles Florence , Paul Young , Jian Ni , Gregory Endress , Ping Feng , Fouad Janat , Charles Birse
发明人： Steven Ruben , Ann Ferrie , Craig Rosen , Kimberly Florence , Kenneth Carter , Daniel Soppet , Guo-Liang Yu , Charles Florence , Paul Young , Jian Ni , Gregory Endress , Ping Feng , Fouad Janat , Charles Birse
CPC分类号： C07K14/47
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20050239059A1
公开(公告)日：2005-10-27
申请号：US09949925
申请日：2001-09-12
申请人： Steven Ruben , Ann Ferrie , Craig Rosen , Kimberly Florence , Kenneth Carter , Daniel Soppet , Guo-Liang Yu , Charles Florence , Paul Young , Jian Ni , Gregory Endress , Ping Feng , Fouad Janat , Charles Birse
发明人： Steven Ruben , Ann Ferrie , Craig Rosen , Kimberly Florence , Kenneth Carter , Daniel Soppet , Guo-Liang Yu , Charles Florence , Paul Young , Jian Ni , Gregory Endress , Ping Feng , Fouad Janat , Charles Birse
CPC分类号： C07K14/47
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20050214844A1
公开(公告)日：2005-09-29
申请号：US11111953
申请日：2005-04-22
申请人： Paul Moore , Yanggu Shi , Craig Rosen , Steven Ruben , David Lafleur , Henrik Olsen , Reinhard Ebner , Laurie Brewer , Paul Young , John Greene , Ann Ferrie , Guo-Liang Yu , Jian Ni , Ping Feng
发明人： Paul Moore , Yanggu Shi , Craig Rosen , Steven Ruben , David Lafleur , Henrik Olsen , Reinhard Ebner , Laurie Brewer , Paul Young , John Greene , Ann Ferrie , Guo-Liang Yu , Jian Ni , Ping Feng
IPC分类号： G01N33/53 , A61K38/00 , A61K48/00 , A61P43/00 , C07H21/02 , C07H21/04 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/00 , C12N5/04 , C12N5/06 , C12N5/10 , C12N5/16 , C12N9/00 , C12N15/00 , C12N15/09 , C12N15/10 , C12N15/11 , C12N15/12 , C12P21/02 , C12P21/04 , C12P21/06 , C12Q1/68 , G01N33/566
CPC分类号： C07K14/47
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。
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公开(公告)号：US20050214786A1
公开(公告)日：2005-09-29
申请号：US10921235
申请日：2004-08-19
申请人： Charles Birse , George Komatsoulis , Gil Choi , Henrik Olsen , Jian Ni , Kevin Baker , Craig Rosen , Steven Ruben , Michele Fiscella , Paul Moore , Ping Wei
发明人： Charles Birse , George Komatsoulis , Gil Choi , Henrik Olsen , Jian Ni , Kevin Baker , Craig Rosen , Steven Ruben , Michele Fiscella , Paul Moore , Ping Wei
CPC分类号： C07H21/04 , C07K14/47 , C12Q1/6883
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20080020969A1
公开(公告)日：2008-01-24
申请号：US11780874
申请日：2007-07-20
申请人： David LaFleur , Daniel Soppet , Henrik Olsen , Steven Ruben , Jian Ni , Craig Rosen , Laurie Brewer , Roxanne Duan , Reinhard Ebner
发明人： David LaFleur , Daniel Soppet , Henrik Olsen , Steven Ruben , Jian Ni , Craig Rosen , Laurie Brewer , Roxanne Duan , Reinhard Ebner
IPC分类号： A61K38/00 , A61K48/00 , C07H21/00 , C07K14/00 , C12N15/00 , C12N15/87 , C12N5/06 , C12P21/04 , G01N33/53
摘要： The present invention relates to 36 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
摘要翻译： 本发明涉及36种新型人分泌蛋白和含有编码这种蛋白质的基因的编码区的分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。
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公开(公告)号：US20070190612A1
公开(公告)日：2007-08-16
申请号：US11738671
申请日：2007-04-23
申请人： Jian Ni , Steven Ruben , Craig Rosen , Reinhard Ebner , Kimberly Florence , Paul Young , Charles Birse , Kenneth Carter , George Komatsoulis
发明人： Jian Ni , Steven Ruben , Craig Rosen , Reinhard Ebner , Kimberly Florence , Paul Young , Charles Birse , Kenneth Carter , George Komatsoulis
CPC分类号： C07K14/47 , A01K2217/075 , A61K38/00
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20070154912A1
公开(公告)日：2007-07-05
申请号：US11566261
申请日：2006-12-04
申请人： Paul Young , John Greene , Ann Ferrie , Steven Ruben , Craig Rosen , Roxanne Duan , Jing-Shan Hu , Kimberly Florence , Henrik Olsen , Reinhard Ebner , Laurie Brewer , Paul Moore , Yanggu Shi , David LaFleur , Jian Ni
发明人： Paul Young , John Greene , Ann Ferrie , Steven Ruben , Craig Rosen , Roxanne Duan , Jing-Shan Hu , Kimberly Florence , Henrik Olsen , Reinhard Ebner , Laurie Brewer , Paul Moore , Yanggu Shi , David LaFleur , Jian Ni
CPC分类号： C12Q1/6883 , A61K38/00 , C07K14/47 , G01N33/6893
摘要： The present invention relates to 87 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
摘要翻译： 本发明涉及87种新的人分泌蛋白和含有编码这种蛋白质的基因的编码区的分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。
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公开(公告)号：US20060223077A1
公开(公告)日：2006-10-05
申请号：US11229770
申请日：2005-09-20
申请人： Jian Ni , Reinhard Ebner , David LaFleur , Paul Moore , Henrik Olsen , Craig Rosen , Steven Ruben , Daniel Soppet , Paul Young , Yanggu Shi , Kimberly Florence , Ying-Fei Wei , Charles Florence , Jing-Shan Hu , Yi Li , Hla Kyaw , Carrie Fischer , Ann Ferrie , Ping Fan , Ping Feng , Gregory Endress , Patrick Dillon , Kenneth Carter , Laurie Brewer , Guo-Liang Yu , Zhizhen Zeng , John Greene
发明人： Jian Ni , Reinhard Ebner , David LaFleur , Paul Moore , Henrik Olsen , Craig Rosen , Steven Ruben , Daniel Soppet , Paul Young , Yanggu Shi , Kimberly Florence , Ying-Fei Wei , Charles Florence , Jing-Shan Hu , Yi Li , Hla Kyaw , Carrie Fischer , Ann Ferrie , Ping Fan , Ping Feng , Gregory Endress , Patrick Dillon , Kenneth Carter , Laurie Brewer , Guo-Liang Yu , Zhizhen Zeng , John Greene
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
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