公开(公告)号：US07979132B2

公开(公告)日：2011-07-12

申请号：US12508453

申请日：2009-07-23

申请人： John Erickson

发明人： John Erickson

IPC分类号： A61N1/18

CPC分类号： A61N1/378 ,  A61N1/3708 ,  A61N1/40

摘要： The application relates to a stimulation device with power conservation functionality. In implantable devices, power supplies may be limited. Replenishing these power supplies may require costly surgery or periodic recharging depending on the model. A method may be implemented that skips or drops periodic pulses without apparently changing the frequency of the pulses. In this manner, the dropped pulses may be undetected by the patient. On the other hand, the dropped pulse represents power savings. Dropping one in ten pulses may lead to a 10% energy savings. The stimulation device may implement the method with one or more counters implemented in hardware or software.

摘要翻译： 该应用涉及具有功率节省功能的刺激装置。 在可植入装置中，电源可能受到限制。 补充这些电源可能需要昂贵的手术或定期充电取决于型号。 可以实现跳过或丢弃周期性脉冲而不明显改变脉冲频率的方法。 以这种方式，丢失的脉冲可能不被患者检测。 另一方面，掉落的脉冲代表功率节省。 掉下十分之一的脉冲可能会节省10％的能量。 刺激装置可以用在硬件或软件中实现的一个或多个计数器来实施该方法。

公开(公告)号：US20100077606A1

公开(公告)日：2010-04-01

申请号：US12631321

申请日：2009-12-04

申请人： Damon Ray Black ,  Terry Daglow ,  John Erickson ,  Robert Earl Jones ,  B. Reno Lauro

发明人： Damon Ray Black ,  Terry Daglow ,  John Erickson ,  Robert Earl Jones ,  B. Reno Lauro

IPC分类号： H01R43/00

CPC分类号： H01R43/00 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/056

摘要： An implantable, substantially isodiametric, low resistance implantable lead having at least one electrode positioned in a stimulation/sensing portion of the lead as well as a method of manufacturing the same. At least the stimulation/sensing portion is unitized through partially surrounding and supporting insulation and conductive element(s) of the stimulation/sensing portion with a fused matrix of material having mechanical properties consistent with a body of the lead.

摘要翻译： 具有至少一个电极位于引线的刺激/感测部分中的可植入的，基本上等径的低电阻可植入引线以及其制造方法。 至少刺激/感测部分通过部分地围绕和支撑刺激/感测部分的绝缘和导电元件而被整合，所述绝缘和导电元件具有与导体主体一致的机械特性的材料的熔融基质。

公开(公告)号：US20080060224A1

公开(公告)日：2008-03-13

申请号：US11938808

申请日：2007-11-13

申请人： Saunders Whittlesey ,  Douglas Robinson ,  John Erickson

发明人： Saunders Whittlesey ,  Douglas Robinson ,  John Erickson

IPC分类号： A43B7/14 ,  A43B5/00

CPC分类号： A43B3/0005 ,  A43B5/001 ,  A43B13/14 ,  A43B23/0235 ,  A43B23/0275 ,  A43C1/00 ,  A43C11/00 ,  A61B5/1036 ,  A61B5/6807 ,  A61B2560/0214 ,  A63B69/0059 ,  A63B69/3608 ,  A63B69/3667 ,  A63B2069/367 ,  A63B2102/32 ,  A63B2220/56 ,  A63B2220/833 ,  A63B2220/836

摘要： Active-response golf shoes are disclosed. The golf shoes include at least one sensor, a controller, and at least one active-response element. The sensor and controller operate to rapidly determine if a golfer is walking or swinging a golf club. Once this determination is made the controller and active-response element rapidly change the shoe's characteristics. If the controller determines that the golfer is walking, the shoe provides a soft and flexible walking platform. If the controller determines that the golfer is swinging, the shoe morphs or changes automatically to provide a stable hitting platform. The controller senses various predetermined conditions such as pressure under the ball of the user's foot to determine whether the golfer is walking or swinging. The active-response elements may be a sole adjuster, a lace adjuster, and/or an upper adjuster. Methods of determining the golfer's type of movement are also disclosed.

摘要翻译： 公开了主动反应高尔夫球鞋。 高尔夫鞋包括至少一个传感器，控制器和至少一个主动响应元件。 传感器和控制器可以快速确定高尔夫球手是走路还是摆动高尔夫球杆。 一旦做出这一决定，控制器和主动响应元件就会迅速改变鞋子的特性。 如果控制器确定高尔夫球手正在行走，鞋子将提供一个柔软而灵活的步行平台。 如果控制器确定高尔夫球手正在摆动，则鞋会自动变形或改变，以提供稳定的打击平台。 控制器感测各种预定条件，例如用户脚的球下方的压力，以确定高尔夫球手是走路还是摆动。 主动响应元件可以是唯一调节器，花边调节器和/或上调节器。 还公开了确定高尔夫球手运动类型的方法。

公开(公告)号：US20060293286A1

公开(公告)日：2006-12-28

申请号：US11490155

申请日：2006-07-21

申请人： John Erickson ,  Michael Eissenstat ,  Abelardo Silva ,  Sergei Gulnik

发明人： John Erickson ,  Michael Eissenstat ,  Abelardo Silva ,  Sergei Gulnik

IPC分类号： C07F9/02 ,  A61K31/66 ,  C07D277/62 ,  C07D263/60 ,  C07D319/14 ,  A61K31/428 ,  A61K31/423

CPC分类号： C12N9/88 ,  A61K31/337 ,  C07D275/03 ,  C07D307/20 ,  C07D491/04 ,  C07D493/04 ,  C07D495/04 ,  C07K2299/00 ,  C12N9/506 ,  G16B15/00 ,  G16B20/00 ,  G16C20/50 ,  Y02A50/406 ,  Y02A50/47 ,  Y02A50/471 ,  Y02A90/26

摘要： Resistance-repellent and multidrug resistant retroviral protease inhibitors are provided. Pharmaceutical composition comprising such compounds, and methods of using such compounds to treat HIV infections in mammals, are also provided.

摘要翻译： 提供抗驱虫和多药耐药的逆转录病毒蛋白酶抑制剂。 还提供了包含这些化合物的药物组合物，以及使用这些化合物治疗哺乳动物HIV感染的方法。

公开(公告)号：US20060258577A1

公开(公告)日：2006-11-16

申请号：US10833304

申请日：2004-04-28

申请人： John Erickson ,  Abelardo Silva

发明人： John Erickson ,  Abelardo Silva

IPC分类号： A61K38/16 ,  A61K38/10 ,  A61K38/06 ,  A61K38/08 ,  C07K14/18 ,  C07K7/08 ,  C07K7/06

CPC分类号： C07K14/005 ,  A61K38/162 ,  C12N2770/20022

摘要： The invention provides compositions and methods that are useful for preventing and treating a coronavirus infection in a subject. More specifically, the invention provides peptides and conjugates and pharmaceutical compositions containing those peptides and conjugates that block fusion of a coronavirus, such as the SARS virus, to a target cell. This blocking mechanism prevents or treats a coronavirus infection, such as a SARS infection, in a subject, such as a human subject.

摘要翻译： 本发明提供可用于预防和治疗受试者冠状病毒感染的组合物和方法。 更具体地，本发明提供了含有阻断冠状病毒例如SARS病毒融合的那些肽和缀合物的肽和缀合物和药物组合物与靶细胞。 这种阻断机制防止或治疗诸如人受试者的受试者中的冠状病毒感染，例如SARS感染。

公开(公告)号：US20060241716A1

公开(公告)日：2006-10-26

申请号：US11426466

申请日：2006-06-26

申请人： Philip Finch ,  Scott Drees ,  John Erickson

发明人： Philip Finch ,  Scott Drees ,  John Erickson

IPC分类号： A61N1/18

CPC分类号： A61N1/36021 ,  A61N1/0558 ,  A61N1/36017 ,  A61N1/36071

摘要： In one embodiment, a method electrically stimulates an area in a spinal disc. The method comprises: implanting at least one steerable lead at a placement site for stimulating a spinal disc such that the lead is disposed exterior and immediately adjacent to and circumferentially along an annulus of the spinal disc, the at least one lead including a plurality of electrodes distributed along a majority of a circumference of the annulus; connecting the lead to a signal generator; and generating electrical stimulation pulses using the generator to stimulate targeted portions of the spinal disc, wherein the stimulation of the targeted portion of the spinal disc sufficiently stimulates nerve tissue within the spinal disc to prevent communication of pain signals originating in the spinal disc without damaging tissue of the spinal disc.

摘要翻译： 在一个实施例中，一种电刺激脊椎盘中的区域的方法。 该方法包括：在放置位置处植入至少一个可操纵的引线，用于刺激脊椎盘，使得引线设置在脊椎盘的环形的外侧并且沿着脊椎盘的环形区域周向地设置，所述至少一个引线包括多个电极 沿着圆环的大部分圆周分布; 将引线连接到信号发生器; 以及使用所述发生器产生电刺激脉冲以刺激所述脊椎盘的目标部分，其中所述脊髓盘的目标部分的刺激充分地刺激所述脊椎盘内的神经组织，以防止源自所述脊髓盘的疼痛信号的通信而不损伤组织 的脊椎盘。

公开(公告)号：US20060200210A1

公开(公告)日：2006-09-07

申请号：US11383107

申请日：2006-05-12

申请人： John Erickson

发明人： John Erickson

IPC分类号： A61N1/34

CPC分类号： A61N1/378 ,  A61N1/3708 ,  A61N1/40

摘要： The application relates to a stimulation device with power conservation functionality. In implantable devices, power supplies may be limited. Replenishing these power supplies may require costly surgery or periodic recharging depending on the model. A method may be implemented that skips or drops periodic pulses without apparently changing the frequency of the pulses. In this manner, the dropped pulses may be undetected by the patient. On the other hand, the dropped pulse represents power savings. Dropping one in ten pulses may lead to a 10% energy savings. The stimulation device may implement the method with one or more counters implemented in hardware or software.

公开(公告)号：US20060171469A1

公开(公告)日：2006-08-03

申请号：US11394753

申请日：2006-03-31

申请人： Pierre Costa ,  Ahmad Ansari ,  John Erickson

发明人： Pierre Costa ,  Ahmad Ansari ,  John Erickson

IPC分类号： H04N11/04 ,  H04N7/12 ,  H04B1/66 ,  H04N11/02

CPC分类号： H04N19/172 ,  H04N19/115 ,  H04N19/132 ,  H04N19/15 ,  H04N19/152 ,  H04N19/169 ,  H04N19/176 ,  H04N19/188 ,  H04N19/30 ,  H04N19/40 ,  H04N19/46 ,  H04N19/60 ,  H04N19/61 ,  H04N19/85 ,  H04N19/88 ,  H04N19/91 ,  H04N21/23418 ,  H04N21/2343 ,  H04N21/235 ,  H04N21/23614 ,  H04N21/238 ,  H04N21/23805 ,  H04N21/4305 ,  H04N21/435 ,  H04N21/44004 ,  H04N21/8456

摘要： A method comprises determining a plurality of time intervals Tp and Tn within a variable bit rate (VBR) representation of an image sequence. The time intervals Tp are those in which a number of blocks of information per unit time is greater than a baseline value. The time intervals Tn are those in which a number of blocks of information per unit time is less than the baseline value. A second representation of the image sequence is created in which some blocks of information Bp are removed from the time intervals Tp and interlaced with blocks of information Bn in the time intervals Tn to reduce a variation in a number of blocks of information per unit time between the time intervals Tp and Tn.

公开(公告)号：US20060113783A1

公开(公告)日：2006-06-01

申请号：US11334896

申请日：2006-01-06

申请人： John Erickson

发明人： John Erickson

IPC分类号： B60S9/02

CPC分类号： B60S9/02

摘要： An electronic controller for a vehicle leveling system comprises an extend-enable switch, a retract-enable switch, an all-activate switch, and at least one group-activate switch. It is configured to generate an all-extend electronic signal upon coordinated actuation of the extend-enable switch and the all-activate switch, an all-retract electronic signal upon coordinated actuation of the retract-enable switch and the all-activate switch, a group-extend electronic signal upon coordinated actuation of the extend-enable switch and the group-activate switch, and a group-retract electronic signal upon coordinated actuation of the retract-enable switch and the group-activate switch. Vehicle leveling systems having the electronic controller further include a plurality of jacks operably controlled by the electronic controller and a power system.

摘要翻译： 一种用于车辆调平系统的电子控制器，包括延伸使能开关，收回使能开关，全激活开关和至少一个组激活开关。 它被配置成在扩展使能开关和全激活开关的协调致动时产生全延伸电子信号，在缩回启动开关和全激活开关的协调致动时，全缩回电子信号， 在延伸使能开关和组激活开关的协调致动时，组合延伸电子信号，以及在缩回启动开关和组激活开关的协调致动时的组缩回电子信号。 具有电子控制器的车辆调平系统还包括可操作地由电子控制器和电力系统控制的多个千斤顶。

公开(公告)号：US07043990B2

公开(公告)日：2006-05-16

申请号：US10470145

申请日：2002-01-30

申请人： Xiping Wang ,  Robert J. Ross ,  James A. Mattson ,  John Erickson ,  John W. Forsman ,  Earl A. Geske ,  Michael A. Wehr

发明人： Xiping Wang ,  Robert J. Ross ,  James A. Mattson ,  John Erickson ,  John W. Forsman ,  Earl A. Geske ,  Michael A. Wehr

IPC分类号： G01N33/46 ,  G01N3/30

CPC分类号： G01N33/46 ,  G01N3/20 ,  G01N2203/0003 ,  G01N2203/0007 ,  G01N2203/0023 ,  G01N2203/0075 ,  G01N2291/0238 ,  G01N2291/02827 ,  G01N2291/0421 ,  G01N2291/0422

摘要： A system for and method of evaluating a log. The system includes an analysis module having at least one input terminal connectable to the at least one input device. The at least one input terminal is operable to receive at least one signal representing at least one measured property of the log and at least one determined parameter of the log determined in response to an energy being applied to the log. The analysis module further includes a processor coupled to the at least one input terminal. The processor determines a predictive modulus of elasticity (MOE) of the log based at least in part on the at least one measured property and the at least one sensed parameter. The analysis module also includes an output terminal coupled to the processor and connectable to an output device. The output terminal transmits a third signal representing the predictive MOE.

摘要翻译： 用于评估日志的系统和方法。 该系统包括分析模块，该分析模块具有可连接至该至少一个输入装置的至少一个输入端子。 所述至少一个输入端可操作以接收表示所述日志的至少一个测量属性的至少一个信号和响应于施加到所述日志的能量确定的所述对数的至少一个确定的参数。 分析模块还包括耦合到至少一个输入端的处理器。 处理器至少部分地基于至少一个测量属性和至少一个感测参数来确定对数的预测弹性模量（MOE）。 分析模块还包括耦合到处理器并可连接到输出设备的输出端子。 输出端子发送代表预测MOE的第三信号。