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公开(公告)号：US09086404B2
公开(公告)日：2015-07-21
申请号：US11867276
申请日：2007-10-04
CPC分类号： G01N33/5082 , G01N35/1002 , G01N2035/1041
摘要： A method is provided by which a reagent is provided to a living sample, including contacting a thin-film containing a porous body with a living sample containing cells or tissues, and discharging a solution containing at least one or more reagents to a non-contact side of the thin-film by ink-jet to provide the solution to the specific area of the living sample through pores on the thin-film, wherein the smaller diameter of the pores on the porous body relative to the diameter of cells in the living sample enables the reagent to be provided to each individual cell separately. According to this method, the reagent and the reaction product can be fixed while maintaining positioning information of the target substance in the living sample, as a pretreatment for analyzing with high positioning accuracy the target substance in each individual cell in the living sample.
摘要翻译： 提供了一种将试剂提供给活体样品的方法，包括使含有多孔体的薄膜与含有细胞或组织的活体样品接触，并将含有至少一种或多种试剂的溶液排出至非接触 通过喷墨使薄膜的一侧通过薄膜上的孔提供到活体样品的特定区域的溶液，其中多孔体上的孔的直径相对于活体中细胞的直径较小 样品使得可以分别向每个单独的细胞提供试剂。 根据该方法，可以在维持活体样品中的目标物质的定位信息的同时固定试剂和反应产物，作为用于以高定位精度分析活体样品中各个细胞中的目标物质的预处理。
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72.发明申请公开(公告)号：US20150045967A1
公开(公告)日：2015-02-12
申请号：US14381781
申请日：2013-01-15
IPC分类号： F24F11/00
CPC分类号： F24F11/0009 , F24F3/065 , F24F11/30 , F24F11/54 , F24F11/62 , F24F2110/00
摘要： An air-conditioning unit control device controls an air-conditioning unit system including one or more outdoor units and a plurality of indoor units. The air-conditioning unit control device includes an environment target value setting unit to set an environment target value for an environment intended to be achieved by air conditioning through each of the indoor units, a zone setting unit to form one or more groups of the indoor units and set a zone for each of the groups, a zone load calculating unit to calculate a heat load on the set zone, an air conditioning capacity allocation calculating unit to determine an allocation of operation capacity to each of the indoor units and the outdoor units based on power consumption of each of the indoor units and the outdoor units, and a control instructing unit to transmit a control signal based on each operation capacity.
摘要翻译： 空调单元控制装置控制包括一个或多个室外单元和多个室内单元的空调单元系统。 空调单元控制装置包括环境目标值设定单元，用于通过每个室内单元设定要通过空调实现的环境的环境目标值，区域设定单元，以形成一个或多个室内组 单元并且为每个组设置区域，区域负载计算单元，用于计算设定区域的热负荷;空调容量分配计算单元，用于确定对每个室内单元和室外单元的操作容量的分配 基于每个室内单元和室外单元的功率消耗，以及控制指示单元，基于每个操作容量发送控制信号。
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公开(公告)号：US20140087408A1
公开(公告)日：2014-03-27
申请号：US13995645
申请日：2011-11-28
IPC分类号： G01N33/574
CPC分类号： G01N33/57415 , C07K14/4756 , G01N33/6848 , G01N2333/4756
摘要： The present invention relates to an information acquisition method of acquiring information of distribution of a protein or peptide in a sample based on mass information obtained by mass spectrometry of the protein or peptide. The method includes mass spectrometry of a definite region of the sample after limited proteolysis of the protein or peptide and acquisition of information relating to distribution using an ion peak that has a two-dimensional intensity distribution having a Pearson product-moment correlation coefficient of 0.5 to more and 1.0 or less in the definite region against the two-dimensional intensity distribution of the parent ion of the protein or the peptide subjected to the limited proteolysis and has a peak intensity ratio of larger than 1.0 against the peak intensity of the integrated spectrum of the parent ion in the definite region, wherein the m/z of the ion peak is greater than 500.
摘要翻译： 本发明涉及基于通过蛋白质或肽的质谱法获得的质量信息获取样品中蛋白质或肽的分布信息的信息获取方法。 该方法包括在蛋白质或肽的有限蛋白水解之后样品的确定区域的质谱，并且使用具有Pearson积矩相关系数为0.5的二维强度分布的离子峰获取与分布有关的信息 相对于蛋白质或经受有限蛋白水解的肽的母离子的二维强度分布，确定区域中的1.0和更小，并且具有大于1.0的峰强度比与峰积分的峰强度比 该定子区域中的母离子，其中离子峰的m / z大于500。
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公开(公告)号：US20140011059A1
公开(公告)日：2014-01-09
申请号：US14005977
申请日：2012-03-29
IPC分类号： H01M10/50
CPC分类号： H01M10/625 , B60L1/003 , B60L50/16 , B60L50/62 , B60L50/64 , B60L58/21 , B60L58/26 , B60L2210/30 , B60L2210/40 , H01M2/1077 , H01M10/613 , H01M10/647 , H01M10/6552 , H01M10/6554 , H01M10/6555 , H01M10/6556 , H01M10/658 , Y02T10/6217 , Y02T10/7005 , Y02T10/7022 , Y02T10/7061 , Y02T10/7077 , Y02T10/7241
摘要： A power supply device includes a battery cell stack (5) constructed of a plurality of stacked, rectangular battery cells, and a cooling pipe (60) disposed in a thermally coupled state over one surface of the battery cell stack (5), the cooling pipe (60) being adapted to perform a heat exchange with the battery cell stack (5) by allowing a refrigerant to flow inside the pipe, wherein a plurality of rows of the cooling pipes (60) are spaced apart from each other over the one surface of the battery cell stack (5), and a resin member is placed between the spaced-apart cooling pipes (60) such that the one surface of the battery cell stack (5) is covered in a sealed state.
摘要翻译： 电源装置包括由多个堆叠的矩形电池单元构成的电池单元堆叠（5）和在电池单元堆（5）的一个表面上以热耦合状态设置的冷却管（60），冷却 管（60）适于通过允许制冷剂在管内流动而与电池单元堆（5）进行热交换，其中多排冷却管（60）彼此间隔开 电池单元堆叠（5）的表面，并且树脂构件被放置在间隔开的冷却管（60）之间，使得电池单元堆叠（5）的一个表面被密封地覆盖。
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公开(公告)号：US08623656B2
公开(公告)日：2014-01-07
申请号：US13052272
申请日：2011-03-21
申请人： Manabu Komatsu , Hiroyuki Hashimoto
发明人： Manabu Komatsu , Hiroyuki Hashimoto
CPC分类号： H01J49/10 , B01L3/5085 , H01J49/40 , Y10T436/11 , Y10T436/112499 , Y10T436/25 , Y10T436/2575
摘要： A test specimen that has one or more chemical substances fixed to prescribed plural independent positions on a substrate, and the quantities of the chemical substances fixed at the respective prescribed positions are the total of integer multiples of existence quantity units defined for the respective chemical substances in the range from 1 amol to 1 nmol (excluding the case in which the total quantity is zero).
摘要翻译： 将具有固定在基板上规定的多个独立位置的一种以上的化学物质的试样和固定在各规定位置的化学物质的量作为对各化学物质定义的存在量单位的整数倍的总和 范围从1 amol到1 nmol（不包括总量为零的情况）。
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公开(公告)号：US08509605B2
公开(公告)日：2013-08-13
申请号：US11898860
申请日：2007-09-17
申请人： Hiroyuki Hashimoto
发明人： Hiroyuki Hashimoto
CPC分类号： H04N5/85 , G03B31/06 , H04N21/23412 , H04N21/2368 , H04N21/4307 , H04N21/4341 , H04N21/43637 , H04N21/44012
摘要： An amplifier includes a first reception section which receives multimedia data via the Internet, a first separation section which separates sound data from the multimedia data, a synchronization data generation section which generates synchronization data based on the sound data, and a synchronization data transmission section which transmits the synchronization data to a set-top box via an infrared communication channel; and the set-top box includes a second reception section which receives the multimedia data via the Internet, a second separation section which separates image data from the multimedia data, a synchronization data reception section which receives the synchronization data via the infrared communication channel, and a matching section which determines reproduction target image data based on the synchronization data.
摘要翻译： 放大器包括经由因特网接收多媒体数据的第一接收部分，从多媒体数据分离声音数据的第一分离部分，基于声音数据产生同步数据的同步数据产生部分和同步数据发送部分， 经由红外通信信道将同步数据发送到机顶盒; 并且机顶盒包括经由因特网接收多媒体数据的第二接收部分，从多媒体数据分离图像数据的第二分离部分，经由红外通信信道接收同步数据的同步数据接收部分，以及 匹配部分，其基于同步数据确定再现目标图像数据。
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公开(公告)号：US08479534B2
公开(公告)日：2013-07-09
申请号：US12669788
申请日：2008-07-16
申请人： Yoshihisa Tachibana , Takashi Nishiyama , Kazuhide Saito , Kazuaki Mizukami , Hiroyuki Hashimoto , Takeshi Ishii , Hiroshi Yamamoto
发明人： Yoshihisa Tachibana , Takashi Nishiyama , Kazuhide Saito , Kazuaki Mizukami , Hiroyuki Hashimoto , Takeshi Ishii , Hiroshi Yamamoto
IPC分类号： F25D3/00
CPC分类号： B67D1/0884 , B01D61/025 , B67D1/0004 , B67D1/0015 , B67D1/0016 , B67D1/0021 , B67D1/04 , B67D1/0406 , B67D1/0864 , B67D1/0888 , B67D2210/00049 , F25B25/005 , F25B2400/06 , F25C1/00 , F25D31/002
摘要： To provide a beverage dispenser capable of appropriately and smoothly supplying a supercooled beverage.[Solving Means] The present invention provides a beverage dispenser 1 which supplies a beverage brought into a supercooled state at a solidifying point or less and which releases the supercooled state in the outside, and the beverage dispenser includes a primary cooling device 13 which cools the beverage to an ice point or so, a beverage supply circuit 7 which supplies the beverage cooled by the primary cooling device 13 to the outside, a brine circuit 31 through which an antifreezing liquid cooled to the solidifying point or less of the beverage is circulated, and a heat exchanger 16 for supercooling the beverage, which performs heat exchange between the beverage flowing through the beverage supply circuit 7 and the antifreezing liquid flowing through the brine circuit 31.
摘要翻译： 提供能够适当且平稳地供应过冷饮料的饮料分配器。 本发明提供了一种饮料分配器1，其将凝固点或更低固化点处于过冷状态的饮料供给并且在外部释放过冷状态，并且饮料分配器包括主冷却装置13，冷却装置 将饮料供给到冰点的饮料供给回路7，将由一次冷却装置13冷却的饮料供给到外部，将冷却至饮料的凝固点以下的防冻液循环通过的盐水回路31， 以及用于过冷却饮料的热交换器16，其在流过饮料供应回路7的饮料和流过盐水回路31的防冻液之间进行热交换。
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78.发明授权Information acquisition method, information acquisition apparatus and disease diagnosis method 有权信息采集方法，信息获取装置及疾病诊断方法公开(公告)号：US08436535B2
公开(公告)日：2013-05-07
申请号：US12712131
申请日：2010-02-24
申请人： Hiroyuki Hashimoto , Katsuaki Kuge , Manabu Komatsu , Kumi Nakamura , Kazuhiro Ban , Takeshi Imamura , Shin Kobayashi , Tadashi Okamoto
发明人： Hiroyuki Hashimoto , Katsuaki Kuge , Manabu Komatsu , Kumi Nakamura , Kazuhiro Ban , Takeshi Imamura , Shin Kobayashi , Tadashi Okamoto
IPC分类号： H01J17/26
CPC分类号： G01N33/6848 , G01N33/4833
摘要： An information acquisition method for acquiring information on a target object, that includes a step of promoting ionization of the target object using a substance for promoting ionization of the target object to cause the target object to emit, and a step of acquiring information on the mass of the flew target object using time-of-flight secondary ion mass spectrometry.
摘要翻译： 一种用于获取关于目标对象的信息的信息获取方法，其包括使用促进所述目标对象的电离的物质促进所述目标对象的电离以使所述目标对象发射的步骤以及获取所述质量信息的步骤 的飞行目标物体使用飞行时间二次离子质谱法。
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公开(公告)号：US20120298859A1
公开(公告)日：2012-11-29
申请号：US13575600
申请日：2011-01-31
申请人： Koichi Tanji , Manabu Komatsu , Hiroyuki Hashimoto
发明人： Koichi Tanji , Manabu Komatsu , Hiroyuki Hashimoto
IPC分类号： H01J49/26
CPC分类号： H01J49/0036 , H01J49/0004
摘要： A more effective noise reduction method is provided. In the method, when mass spectrum information having a spatial distribution is processed, the whole data is taken as three-dimensional data (positional information is stored in an xy plane, and spectral information is stored along a z-axis direction), and three-dimensional wavelet noise reduction is performed by applying preferable basis functions to a spectral direction and a peak distribution direction (in-plane direction).
摘要翻译： 提供了更有效的降噪方法。 在该方法中，当处理具有空间分布的质谱信息时，将整个数据作为三维数据（位置信息存储在xy平面中，并且光谱信息沿z轴方向存储），并且三个 通过对光谱方向和峰分布方向（面内方向）应用优选的基函数来进行维小波噪声降低。
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80.发明申请AGENT FOR PREVENTING OR TREATING CROHN'S DISEASE, COMPRISING ORGANIC ACID POLYMER 审中-公开用于预防或治疗乳腺疾病的药剂，包含有机酸聚合物公开(公告)号：US20120244102A1
公开(公告)日：2012-09-27
申请号：US13514083
申请日：2011-01-26
申请人： Hiroyuki Hashimoto , Toshihiko Kumazawa , Motohiro Takeda , Takahito Jomori , Chihiro Hibi , Kuniharu Mizuno
发明人： Hiroyuki Hashimoto , Toshihiko Kumazawa , Motohiro Takeda , Takahito Jomori , Chihiro Hibi , Kuniharu Mizuno
IPC分类号： A61K31/765 , A61P1/04
CPC分类号： A61K31/80
摘要： The present invention is to provide an agent for treating Crohn's disease that is of unknown cause and for which no radical therapeutic drug is present. Provided is an agent for preventing or treating Crohn's disease, comprising an organic acid polymer represented by the following formula: [(O1/2)3Ge-A-CO2H]n, wherein n is 100-1,000, and A is a lower alkyl group. Preferably, A is a C1-C3 lower alkyl group and the degree of polymerization n is 200-900. The organic acid polymer according to the present invention is effective as an agent for treating Crohn's disease.
摘要翻译： 本发明提供一种用于治疗克罗恩病的药剂，其原因不明，没有基础治疗药物存在。 本发明提供一种预防或治疗克罗恩病的药剂，其含有下式所示的有机酸聚合物：[（O1 / 2）3Ge-A-CO2H] n，其中n为100-1,000，A为低级烷基 。 优选地，A是C1-C3低级烷基，聚合度n是200-900。 根据本发明的有机酸聚合物作为治疗克罗恩病的药剂是有效的。
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