公开(公告)号：US20100120072A1

公开(公告)日：2010-05-13

申请号：US12593160

申请日：2008-04-15

Applicant: Robert M. Lorence ,  Ming Lu

Inventor： Robert M. Lorence ,  Ming Lu

IPC: G01N33/574

CPC classification number: G01N33/57415 ,  G01N2333/71 ,  G01N2800/52

Abstract: The expression of Her-2/neu protein on circulating cancer cells in a sample of blood or peripheral blood mononuclear cells (PBMCs) is detected by performing a sensitive Her-2/neu immunoassay. There is no need to isolate the cancer cells before performing the immunoassay. A positive result indicates the expression of Her-2/neu on cancer cells in the blood sample. This method can be used to identify cancer patients who are likely to benefit from treatment with an anticancer agent that targets Her-2/neu, such as trastuzumab (HERCEPTIN), lapatinib, CP-724,714, NKI-272, and BMS-599626

Abstract translation: 通过进行敏感的Her-2 / neu免疫测定来检测Her-2 / neu蛋白对血液或外周血单核细胞（PBMC）样品中循环癌细胞的表达。 在进行免疫测定之前，不需要分离癌细胞。 阳性结果表明Her-2 / neu在血液样品中对癌细胞的表达。 该方法可用于鉴定可能受到靶向Her-2 / neu的抗癌剂（例如曲妥珠单抗（HERCEPTIN），拉帕替尼，CP-724,714，NKI-272和BMS-599626）的治疗有益的癌症患者。

公开(公告)号：US07659546B2

公开(公告)日：2010-02-09

申请号：US11317281

申请日：2005-12-23

Applicant: Ming Lu ,  Geoffrey Wen Tai Shuy

Inventor： Ming Lu ,  Geoffrey Wen Tai Shuy

IPC: H01L29/22 ,  H01L27/15

CPC classification number: H01L33/62 ,  H01L2924/0002 ,  H01L2924/00

Abstract: A light emitting device firstly includes a light emitting diode (LED) structure, having a top surface with a light emitting region. The device also has a heterojunction within the device structure, the heterojunction having a p-type and an n-type semiconductor layer, and a plurality of electrodes positioned on the top surface, each being electrically connected to one of the p-type and n-type semiconductor layers. At least a first and a second electrodes are connected to a same type semiconductor layer and are physically separated from each other. The device further includes a first and a second heterojunction regions within the heterojunction, each being respectively defined between one of the first and second electrodes and one of the other electrodes connected to the other type semiconductor layer. The first and second heterojunction regions are alternatively driven for emitting lights in the time domain.

Abstract translation: 发光器件首先包括具有发光区域的顶表面的发光二极管（LED）结构。 该器件还在器件结构内具有异质结，异质结具有p型和n型半导体层，以及位于顶表面上的多个电极，每个电极电连接到p型和n型半导体层之一 型半导体层。 至少第一和第二电极连接到相同类型的半导体层并且在物理上彼此分离。 该器件还包括异质结内的第一和第二异质结区域，每个异质结区域分别限定在第一和第二电极中的一个之间以及连接到另一类型半导体层的其它电极之一。 交替驱动第一和第二异质结区域以在时域中发光。

公开(公告)号：US20090291920A1

公开(公告)日：2009-11-26

申请号：US12296458

申请日：2007-04-18

Applicant: Ming Lu ,  Robert M. Lorence

Inventor： Ming Lu ,  Robert M. Lorence

IPC: A61K31/566 ,  C12Q1/02 ,  A61K31/565 ,  A61K31/4353 ,  A61K31/4196

CPC classification number: G01N33/57492 ,  G01N33/743 ,  G01N2333/723 ,  G01N2800/52

Abstract: The expression of a steroid receptor from circulating carcinoma cells in a blood sample is detected by isolating the carcinoma cells from the blood sample, making an extract from the isolated carcinoma cells and then performing on the extract a sensitive immunoassay capable of detecting the carcinoma cell-associated steroid receptor. A positive result indicates the presence of the steroid receptor in the carcinoma cells. This method can be used to identify cancer patients who are likely to benefit from treatment with an endocrine therapeutic agent.

Abstract translation: 通过从血液样品中分离癌细胞，从分离的癌细胞中分离出一种提取物，然后对该提取物进行能够检测癌细胞的敏感的免疫测定法，检测血液样品中来自循环癌细胞的类固醇受体的表达， 相关的类固醇受体。 阳性结果表明癌细胞中类固醇受体的存在。 该方法可用于鉴定可能受益于内分泌治疗剂治疗的癌症患者。

公开(公告)号：US20090252950A1

公开(公告)日：2009-10-08

申请号：US12062637

申请日：2008-04-04

Applicant: Been Yu Liaw ,  Ming Lu

Inventor： Been Yu Liaw ,  Ming Lu

IPC: B32B9/00 ,  G03F7/26

CPC classification number: H01L23/15 ,  H01L23/3672 ,  H01L23/3677 ,  H01L23/49827 ,  H01L33/486 ,  H01L33/60 ,  H01L33/62 ,  H01L33/641 ,  H01L2924/0002 ,  H01L2933/0066 ,  Y10T428/24999 ,  H01L2924/00

Abstract: An alumina substrate and method of making an alumina substrate using oxidation is provided. Generally, photoresist masks are used to protect selected areas of an aluminum layer. The unprotected or exposed areas of the aluminum layer are then oxidized during a photolithography process. The protected, unexposed areas of the aluminum layer retain their conductive properties while the oxidized areas are converted to alumina, or aluminum oxide, which is non-conductive. Accordingly, an alumina substrate having conductive areas of aluminum is formed. In one embodiment, the alumina substrate includes an alumina layer, one or more aluminum vias formed within the alumina layer, each of the one or more aluminum vias extending between the bottom of the alumina layer and the top of the alumina layer, wherein the one or more aluminum vias are integrally formed within the alumina layer.

Abstract translation: 提供氧化铝基板和使用氧化制造氧化铝基板的方法。 通常，光致抗蚀剂掩模用于保护铝层的选定区域。 然后在光刻过程中氧化铝层的未受保护或暴露的区域。 铝层的受保护的未曝光区域保持其导电性能，而氧化区域转变为不导电的氧化铝或氧化铝。 因此，形成具有铝导电面积的氧化铝基板。 在一个实施例中，氧化铝衬底包括氧化铝层，在氧化铝层内形成的一个或多个铝通孔，在氧化铝层的底部和氧化铝层的顶部之间延伸的一个或多个铝通孔中的每一个，其中一个 或更多的铝通孔一体地形成在氧化铝层内。

公开(公告)号：US20080211369A1

公开(公告)日：2008-09-04

申请号：US11727714

申请日：2007-03-28

Applicant: Zhikuan Zhang ,  Ming Lu ,  Lydia Leung ,  Kelvin Ll ,  Enboa Wu

Inventor： Zhikuan Zhang ,  Ming Lu ,  Lydia Leung ,  Kelvin Ll ,  Enboa Wu

IPC: H01J7/24

CPC classification number: H05B33/0803 ,  F21K9/00 ,  F21V23/0435 ,  F21V23/0442 ,  F21V29/503 ,  F21V29/86 ,  F21V29/89 ,  F21Y2115/10 ,  H05B33/0857

Abstract: A remote-controllable lighting device comprising a first substrate and an adjacent second substrate maintained in a spaced apart relationship to allow airflow therebetween and at least partly overlapping each other, at least the second substrates carrying thereon at least one emission sources, the first substrate being located towards a proximal end of the device and the second substrate being located towards a distal end of the device; said first substrate being arranged so as to allow light generated by the at least one located second light emission source to pass thereby in a direction defining a primary light emission direction and said first light emission source located so as to emit light in said primary light emission direction; said first and second substrate being in thermal communication so as to allow heat generated by the at least one light emission sources to flow between the substrates so as to provide thermal distribution between the substrates, the first and second substrate being formed of a thermally conductive material suitable for convection of the generated heat therefrom; a signal detector for receiving a wirelessly transmitted control signal from a remote control device; said signal receiver being located proximal of the first substrate in the primary light emission direction; and a controller in communication with said signal detector and the light emission sources and for controlling at least one characteristic of at least one light emission source responsive to said control signal.

Abstract translation: 遥控照明装置，包括第一基板和相邻的第二基板，所述第一基板和相邻的第二基板保持间隔开的关系，以允许至少部分地彼此重叠的气流，至少在其上承载有至少一个排放源的第二基板，第一基板 朝向装置的近端定位，并且第二基板朝向装置的远端定位; 所述第一衬底布置成允许由所述至少一个位于第二发光源产生的光在限定初级发光方向的方向上通过，并且所述第一发光源被定位成在所述初级发光中发光 方向; 所述第一和第二基板是热连通的，以便允许至少一个发光源产生的热量在基板之间流动，从而在基板之间提供热分布，第一和第二基板由导热材料 适于从其产生的热量对流; 信号检测器，用于从遥控装置接收无线发送的控制信号; 所述信号接收器位于所述第一基板的初始发光方向的近侧; 以及与所述信号检测器和所述发光源通信并用于响应于所述控制信号来控制至少一个发光源的至少一个特性的控制器。

公开(公告)号：US20080174996A1

公开(公告)日：2008-07-24

申请号：US11654601

申请日：2007-01-18

Applicant: Ming Lu ,  Lei Shi ,  Chak Hau Pang

Inventor： Ming Lu ,  Lei Shi ,  Chak Hau Pang

IPC: F21V5/04

CPC classification number: F21V5/04 ,  F21Y2115/10 ,  G02B19/0028 ,  G02B19/0066 ,  G02B27/144

Abstract: A light-emitting assembly comprising a lens, a first optical source, a second optical source and a third optical source, wherein the lens is disposed forward of said first, second and third optical sources; the third optical source is intermediate the first and second optical sources; and the lens and the first, second and third optical sources are arranged so that light emitted from the first and second optical sources merges at the third optical source after undergoing internal reflection at the lens.

Abstract translation: 一种发光组件，包括透镜，第一光源，第二光源和第三光源，其中所述透镜设置在所述第一，第二和第三光源的前方; 第三光源位于第一和第二光源之间; 并且透镜和第一，第二和第三光源被布置成使得从第一和第二光源发射的光在透镜经历内部反射之后在第三光源处合并。

公开(公告)号：US20080099772A1

公开(公告)日：2008-05-01

申请号：US11589705

申请日：2006-10-30

Applicant: Geoffrey Wen-Tai Shuy ,  Enboa Wu ,  Ming Lu

Inventor： Geoffrey Wen-Tai Shuy ,  Enboa Wu ,  Ming Lu

IPC: H01L33/00 ,  H01L29/207

CPC classification number: H01L27/156 ,  H01L33/385 ,  H01L33/62 ,  H01L2224/48137 ,  H01L2224/48139 ,  H01L2224/49113

Abstract: A light source includes a light emitting diode (LED) module having a continuous substrate, a layer of n-type semiconductor material formed above the substrate, and a layer of p-type semiconductor material formed above the n-type semiconductor material. A p-n junction is formed between the p-type and n-type semiconductor materials. The p-type and n-type semiconductor materials are selected to emit light at the p-n junction when an electric current flows through the p-n junction. The LED module includes a plurality of electric contacts connected to the p-type semiconductor material, and at least one electric contact connected to the n-type semiconductor material. The electric contacts are configured to pass electric current through a plurality of regions in the p-n junction such that the plurality of regions have higher electric current densities and emit light brighter than areas outside of the plurality of regions.

Abstract translation: 光源包括具有连续衬底的发光二极管（LED）模块，在衬底上形成的n型半导体材料层和形成在n型半导体材料上方的p型半导体材料层。 在p型和n型半导体材料之间形成p-n结。 当电流流过p-n结时，选择p型和n型半导体材料在p-n结处发光。 LED模块包括连接到p型半导体材料的多个电触点和连接到n型半导体材料的至少一个电触点。 电触点被配置为使电流通过p-n结中的多个区域，使得多个区域具有较高的电流密度并且发射比多个区域外的区域更亮的光。

公开(公告)号：US20080049699A1

公开(公告)日：2008-02-28

申请号：US11509406

申请日：2006-08-24

Applicant: Gang Li ,  Ming Lu ,  Jialin Zou

Inventor： Gang Li ,  Ming Lu ,  Jialin Zou

IPC: H04B7/216

CPC classification number: H04L1/0025 ,  H04L1/0027 ,  H04L1/1671

Abstract: In an H-ARQ system, when the AN is receiving packet data traffic on the RL from an AT and is generating ACKs and NAKs according to the ability of the AN to properly decode such data, the AN gates-off a DRCLock bit within in a sub-packet duration in which an ACK is transmitted on the FL MAC channel. When it receives an ACK, the AT ignores the non-transmitted DRCLock bit in a current sub-packet duration, and assumes that the DRC channel is “good”. When the AN sends a NAK to the AT, it also sends the DRCLock bit. When the AT receives a NAK in a sub-packet duration, it reads and processes whatever DRCLock bit is received during that sub-packet duration. When no data traffic is transmitted on the RL traffic channel, corresponding DRCLock bits are not gated-off by the AN and are transmitted to the AT. The AT then processes the received DRCLock bits. In an alternative embodiment, transmission of DRCLock is totally eliminated.

Abstract translation: 在H-ARQ系统中，当AN正在从AT接收RL上的分组数据流量时，根据AN对这些数据进行正确解码的能力产生ACK和NAK，AN将关闭一个DRCLock位 在FL MAC信道上发送ACK的子分组持续时间。 当接收到ACK时，AT忽略当前子包持续时间内未发送的DRCLock位，并假定DRC信道为“良好”。 当AN向AT发送NAK时，它还发送DRCLock位。 当AT在子分组持续时间内接收到NAK时，它读取并处理在该子分组持续时间期间接收的任何DRCLock比特。 当在RL业务信道上没有传输数据业务时，相应的DRCLock比特不被AN门控，并被发送给AT。 AT然后处理接收到的DRCLock位。 在替代实施例中，完全消除了DRCLock的传输。

公开(公告)号：US07135257B2

公开(公告)日：2006-11-14

申请号：US10693989

申请日：2003-10-22

Applicant: Ming Lu ,  Bin-Chang Chang ,  Li-Wei Kung

Inventor： Ming Lu ,  Bin-Chang Chang ,  Li-Wei Kung

IPC: G01F9/00 ,  G03C5/00

CPC classification number: G03F1/30 ,  G03F1/28

Abstract: A phase shift mask comprises a transparent substrate having a patterned opaque material layer formed thereupon to form a non-transmissive region of the transparent substrate and an adjoining transmissive region of the transparent substrate. A pit is formed within the transmissive region of the transparent substrate. The pit has a stepped sidewall such as to provide the phase shift mask with enhanced optical performance. The phase shift mask may be fabricated employing a self aligned method.

Abstract translation: 相移掩模包括具有在其上形成的图案化不透明材料层的透明基板，以形成透明基板的非透射区域和透明基板的相邻透射区域。 在透明基板的透射区域内形成凹坑。 凹坑具有阶梯式侧壁，以提供具有增强的光学性能的相移掩模。 可以使用自对准方法来制造相移掩模。

公开(公告)号：US09333231B2

公开(公告)日：2016-05-10

申请号：US14043035

申请日：2013-10-01

Applicant: Jing Cheng ,  Chia-wen Chen ,  Steven Francis Schnittger ,  Ming Lu

Inventor： Jing Cheng ,  Chia-wen Chen ,  Steven Francis Schnittger ,  Ming Lu

IPC: A61K36/725 ,  A61K8/97 ,  A61K8/99 ,  A61Q19/00 ,  A61K36/752 ,  A61K36/756 ,  A61K36/804 ,  A61K36/8998 ,  A61K36/068 ,  A61K36/074 ,  A61K36/076 ,  A61K36/10 ,  A61K36/16 ,  A61K36/185 ,  A61K36/23 ,  A61K36/235 ,  A61K36/236 ,  A61K36/258 ,  A61K36/28 ,  A61K36/41 ,  A61K36/535 ,  A61K36/539 ,  A61K36/65 ,  A61K36/704 ,  A61K36/06 ,  A61K36/69

CPC classification number: A61K36/725 ,  A61K8/97 ,  A61K8/99 ,  A61K36/06 ,  A61K36/068 ,  A61K36/074 ,  A61K36/076 ,  A61K36/10 ,  A61K36/16 ,  A61K36/185 ,  A61K36/23 ,  A61K36/235 ,  A61K36/236 ,  A61K36/258 ,  A61K36/28 ,  A61K36/41 ,  A61K36/535 ,  A61K36/539 ,  A61K36/65 ,  A61K36/69 ,  A61K36/704 ,  A61K36/752 ,  A61K36/756 ,  A61K36/804 ,  A61K36/8998 ,  A61K2800/85 ,  A61Q19/00

Abstract: The present invention relates to topical compositions containing fermented extracts of Traditional Chinese Medicinal (TCM) ingredients for improving the appearance and skin condition of the user. The topical compositions of the present invention are tailored for different users of different skin compositions according to TCM principles. The fermented TCM extracts are characterized by reduced odor and/or color in comparison with unfermented TCM extracts and are therefore more suitable for use in cosmetic products.

Abstract translation: 本发明涉及含有用于改善使用者的外观和皮肤状况的中药（TCM）成分的发酵提取物的局部组合物。 根据TCM原理，本发明的局部组合物针对不同皮肤组合物的不同使用者而定制。 与未发酵的TCM提取物相比，发酵的TCM提取物的特征在于减少气味和/或颜色，因此更适合用于化妆品。