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    Modular intraocular lens designs and methods
    71.
    发明授权
    Modular intraocular lens designs and methods 有权
    模块化眼内透镜设计和方法

    公开(公告)号：US09289287B2

    公开(公告)日：2016-03-22

    申请号：US13969115

    申请日：2013-08-16

    申请人： CLARVISTA MEDICAL, INC. ,  THE REGENTS OF THE UNIVERSITY OF COLORADO, a body corporate

    发明人： Malik Y. Kahook ,  Naresh Mandava ,  Glenn Sussman ,  Paul McLean ,  Robert E. Atkinson

    IPC分类号： A61F2/16

    CPC分类号： A61F2/1648 ,  A61F2/16 ,  A61F2/1613 ,  A61F2/1662 ,  A61F9/0017 ,  A61F9/007 ,  A61F9/00736 ,  A61F2002/1681 ,  A61F2002/1683 ,  A61F2002/1689 ,  A61F2002/169 ,  A61F2002/16902 ,  A61F2220/0025 ,  A61F2250/006

    摘要： A modular IOL system including intraocular primary and secondary components, which, when combined, form an intraocular optical correction device, wherein the secondary component is placed on the primary component within the perimeter of the capsulorhexis, thus avoiding the need to touch or otherwise manipulate the capsular bag. The secondary component may be manipulated, removed, and/or exchanged for a different secondary component for correction or modification of the optical result, on an intra-operative or post-operative basis, without the need to remove the primary component and without the need to manipulate the capsular bag. The primary component may have haptics extending therefrom for centration in the capsular bag, and the secondary component may exclude haptics, relying instead on attachment to the primary component for stability. Such attachment may include actuatable interlocking members.

    摘要翻译： 包括眼内主要和次要组件的模块化IOL系统，当组合时，其组合形成眼内光学校正装置，其中次要部件被放置在胶囊切口的周边内的主要部件上，因此避免了触摸或以其他方式操纵 囊袋。 次要组件可以被操纵，移除和/或交换以用于不同的辅助部件，用于在术中或手术后的基础上校正或修改光学结果，而不需要去除主要部件并且不需要 操纵囊袋。 主要部件可以具有从其延伸的触觉件，用于在囊袋中心分离，并且次要部件可以排除触觉件，而是依赖于连接到主要部件以获得稳定性。 这种附件可以包括可致动的互锁构件。

    INTRAOCULAR LENS
    72.
    发明申请
    INTRAOCULAR LENS 审中-公开
    内窥镜

    公开(公告)号：US20160074153A1

    公开(公告)日：2016-03-17

    申请号：US14843118

    申请日：2015-09-02

    申请人： ART, LIMITED

    发明人： Takayuki Akahoshi ,  Michael Southard

    IPC分类号： A61F2/16

    CPC分类号： A61F2/16 ,  A61F2002/1683 ,  A61F2220/0008 ,  A61F2220/0016

    摘要： A toric intraocular lens is configured for enhanced stability after implantation into a capsular bag of an eye. The intraocular lens has one or more haptics extending from the lens, with stabilization enhanced by configuring the lens to include at least one engagement element configured to cooperate with the interior to the capsular bag to resist relative rotation of the lens. In one aspect of the invention, the engagement element can be provided in the form of one or more rotation-inhibiting projections provided on the lens body and/or the haptics of the lens. In another aspect of the invention, the lens includes an anterior surface which is configured to provide enhanced frictional engagement of the intraocular lens with the interior of the eye. The anterior surface of the lens can be roughened in order to provide the desired frictional engagement.

    摘要翻译： 复曲面眼内透镜被配置成在植入眼袋之后增强稳定性。 眼内透镜具有从透镜延伸的一个或多个触觉件，通过将透镜配置为包括至少一个接合元件，其被配置成与囊袋的内部协作以抵抗透镜的相对旋转而增强了稳定性。 在本发明的一个方面中，接合元件可以设置在设置在透镜体和/或透镜的触觉件上的一个或多个防旋转突起的形式。 在本发明的另一方面，透镜包括前表面，其被配置为提供眼内透镜与眼睛内部的增强的摩擦接合。 透镜的前表面可以被粗糙化以便提供所需的摩擦接合。

    REAL-TIME SURGICAL REFERENCE INDICIUM APPARATUS AND METHODS FOR INTRAOCULAR LENS IMPLANTATION
    74.
    发明申请
    REAL-TIME SURGICAL REFERENCE INDICIUM APPARATUS AND METHODS FOR INTRAOCULAR LENS IMPLANTATION 审中-公开
    实时外科手术参考指标及手术镜片植入方法

    公开(公告)号：US20160051360A1

    公开(公告)日：2016-02-25

    申请号：US14929801

    申请日：2015-11-02

    申请人： Ashok B. Tripathi

    发明人： Ashok B. Tripathi

    IPC分类号： A61F2/16 ,  A61B19/00

    CPC分类号： A61B90/37 ,  A61B2034/107 ,  A61B2090/365 ,  A61F2/16

    摘要： A system, method, and apparatus for performing intraocular lens implantation using real-time surgical reference indicium are disclosed. An example method includes recording a patient specific pre-operative still image of an eye prior to cyclorotation of the eye when a patient lies down for surgery and generating at least one real-time multidimensional visualization of at least a portion of the eye for display. The method further includes using the patient specific pre-operative still image to at least produce at least one virtual surgical reference indicium including an ocular natural vertical axis of the eye and align the at least one virtual surgical reference indicium to the eye in conjunction with the real-time multidimensional visualization of at least a portion of the eye. The patient specific pre-operative still image is captured under a dilation condition selected from the group consisting of natural dilation, chemical dilation, and no dilation.

    摘要翻译： 公开了一种使用实时手术参考标记进行眼内透镜植入的系统，方法和装置。 示例性方法包括当患者躺在手术下时在眼睛的旋转之前记录患者特定的眼睛的手术前静止图像，并且生成眼睛的至少一部分的至少一个实时多维可视化以进行显示。 该方法还包括使用患者特定的术前静止图像至少产生至少一个虚拟手术参考标记，其包括眼睛的眼睛自然垂直轴线，并将至少一个虚拟手术参考标记与眼睛对准 至少一部分眼睛的实时多维可视化。 在选自自然扩张，化学扩张和无扩张的扩张条件下捕获患者特异性手术前静止图像。

    METHOD AND SYSTEM FOR IMPROVING VISION OF AN EYE WITH MACULAR DEGENERATION
    75.
    发明申请
    METHOD AND SYSTEM FOR IMPROVING VISION OF AN EYE WITH MACULAR DEGENERATION 审中-公开
    用于改善眼睛变形的眼睛的方法和系统

    公开(公告)号：US20160015262A1

    公开(公告)日：2016-01-21

    申请号：US14522686

    申请日：2014-10-24

    申请人： David M. Lieberman ,  Jonathan Grierson

    发明人： David M. Lieberman ,  Jonathan Grierson

    IPC分类号： A61B3/00 ,  G02C7/02 ,  A61F2/16 ,  A61B3/107 ,  A61F9/008 ,  A61F2/14

    CPC分类号： G02C7/027 ,  A61F2/145 ,  A61F2/16 ,  A61F9/00802 ,  A61F2009/00872 ,  A61F2009/00882 ,  G02C7/04 ,  G02C2202/10

    摘要： Methods and apparatus are disclosed for diagnosing vision and improving vision, for example by reducing or eliminating the effects of macular degeneration, in a manner which does not interfere with the natural shape of the cornea or its orientation relative to the remainder of the eye, but which changes its surface curvature appropriately to achieve the required correction of vision. The focus of sub-regions of the cornea is adjusted so that different regions focus at a controlled distance about a reference axis. This can be accomplished by shaping the cornea (e.g. through ablation) or by applying an appropriate contact lens or other optical lens.

    摘要翻译： 公开了用于诊断视力和改善视力的方法和装置，例如通过减少或消除黄斑变性的影响，以不影响角膜的自然形状或其相对于眼睛的其余部分的取向的方式，但是 其适当地改变其表面曲率以实现视觉的所需校正。 调整角膜的子区域的焦点，使得不同的区域围绕参考轴线处于受控的距离。 这可以通过使角膜（例如通过消融）成形或通过施加适当的隐形眼镜或其它光学透镜来实现。

    LIQUID CRYSTAL OPTICAL DEVICE WITH ADVANCED ELECTRIC FIELD CONTROL CAPABILITY
    77.
    发明申请
    LIQUID CRYSTAL OPTICAL DEVICE WITH ADVANCED ELECTRIC FIELD CONTROL CAPABILITY 有权
    具有先进电场控制能力的液晶光学器件

    公开(公告)号：US20160000557A1

    公开(公告)日：2016-01-07

    申请号：US14653574

    申请日：2013-12-18

    申请人： LENSVECTOR INC.

    发明人： Tigran GALSTIAN ,  Karen ASATRYAN ,  Vladimir PRESNIAKOV ,  Aram BAGRAMYAN ,  Amir TORK ,  Armen ZOHRABYAN ,  Simon CAREAU

    IPC分类号： A61F2/16 ,  G02B13/00 ,  G02F1/29 ,  G02F1/1343 ,  G02F1/1337

    CPC分类号： A61F2/1627 ,  A61F2/16 ,  A61F2/1648 ,  A61F2210/0076 ,  G02B1/16 ,  G02B13/0075 ,  G02F1/1337 ,  G02F1/134309 ,  G02F1/13439 ,  G02F1/29

    摘要： A liquid crystal optical device is provided, including a layered structure including at least two support substrates. An external hole patterned control electrode is provided on one of the substrates and has an aperture. An internal hole patterned control electrode is provided on one of the substrates within the aperture, the internal and outer control electrodes being separated by a gap, which forms part of the aperture. A weakly conductive material is provided on one of the substrates over the aperture. A planar transparent electrode is provided on another one of the substrates. An alignment surface is provided on the substrates over the electrodes. A layer of liquid crystal material is contained by the substrates and in contact with the alignment surface of the substrates. A floating transparent electrode is provided on a side of one of the substrates opposite the outer and the internal hole patterned electrode.

    摘要翻译： 提供了一种液晶光学器件，其包括包括至少两个支撑衬底的层状结构。 一个外部孔图案化控制电极设置在其中一个基板上并且具有孔。 孔内图案化的控制电极设置在孔内的一个基板上，内部和外部控制电极被形成孔的一部分的间隙分开。 在孔上的一个基底上提供弱导电材料。 平面透明电极设置在另一个基板上。 在电极上的基板上设置对准表面。 液晶材料层由基板包含并与基板的对准表面接触。 浮置的透明电极设置在与外部和内部孔图案化电极相对的一个基板的一侧上。

    WATER SOLUBLE SILICONE MATERIAL
    78.
    发明申请
    WATER SOLUBLE SILICONE MATERIAL 审中-公开
    水溶性硅胶材料

    公开(公告)号：US20150368404A1

    公开(公告)日：2015-12-24

    申请号：US14765054

    申请日：2014-01-31

    申请人： MOMENTIVE PERFORMANCE MATERIALS INC.

    发明人： Weihong Lang ,  Wen P. Liao ,  Susan Nye ,  Kenrick M. Lewis

    IPC分类号： C08G77/44 ,  G02B1/04 ,  C08L83/10

    CPC分类号： C08G77/44 ,  A61B2017/00942 ,  A61F2/14 ,  A61F2/16 ,  A61L27/18 ,  A61L29/06 ,  C08F283/12 ,  C08F290/068 ,  C08G77/46 ,  C08L83/10 ,  G02B1/043 ,  C08F230/08 ,  C08F220/54 ,  C08F226/10 ,  C08F220/20 ,  C08F220/56

    摘要： A water soluble silicone macromer comprising a siloxane backbone having grafted thereto a suitable number of hydrophilic groups to render the macromer water soluble, the macromer comprising a polymerizable functional group grafted to the siloxane backbone. In one aspect, the present invention provides a water soluble silicone macromer having a structure of Formula (1): where M is a hydrophilic group or segment; L is a hydrophilic or hydrophobic linkage; N is a hydrophilic or hydrophobic group or segment. Q is a polymerizable functional group; x is zero or an integer greater than zero; y is zero or an integer greater than zero; v is zero or an integer greater than zero; and z is greater than zero, with the proviso that both y and v are not zero.

    摘要翻译： 包含硅氧烷主链的水溶性硅氧烷大分子单体，其具有接枝到其上的合适数量的亲水基团以使大分子单体水溶性，大分子单体包含接枝到硅氧烷主链的可聚合官能团。 一方面，本发明提供具有式（1）结构的水溶性硅氧烷大分子单体：其中M是亲水基团或链段; L是亲水或疏水键; N是亲水或疏水基团或片段。 Q是可聚合官能团; x为零或大于零的整数; y为零或大于零的整数; v为零或大于零的整数; 并且z大于零，条件是y和v都不为零。