System and process for determining and analysing surface property parameters of substance based on kinetic method

    公开(公告)号:US09719953B2

    公开(公告)日:2017-08-01

    申请号:US14359502

    申请日:2012-01-20

    IPC分类号: G01N27/26 G01R29/24

    CPC分类号: G01N27/26 G01R29/24

    摘要: A system and process for determining and analyzing surface property parameters of a substance based on kinetic method is provided. The system comprises a sample processing system and a detection system. The sample processing system includes a reactor (3), a collector for liquid to be tested (5), and a container for liquid to be tested (6). The detection system includes a detecting electrode (13), a concentration and activity operator, a kinetic data processor, a surface property operation module, and a result output module. The process comprises: having the substance to be tested to be treated with an electrolyte solution, measuring activity of liquid to be tested upon reaction at a pre-set time interval, and processing with the kinetic data processor and the surface property operation module, so as to obtain surface property parameters of the substance to be tested. The present invention adopts kinetic method of ion exchange to overcome the issues associated with long reaction equilibrium time, not easy to determine equilibrium and not easy to accurately determine the value of m. Five parameters of the substance surface property can be calculated with only intercept and gradient of the linear regression equation obtained from the kinetic data, and the total amount of surface charge can also be directly determined.

    Apparatus and Methods for Single-Particle Isolation and Single-Particle Measurement
    83.
    发明申请
    Apparatus and Methods for Single-Particle Isolation and Single-Particle Measurement 审中-公开
    单粒子分离和单粒子测量的装置和方法

    公开(公告)号:US20160375439A1

    公开(公告)日:2016-12-29

    申请号:US15130930

    申请日:2016-04-16

    IPC分类号: B01L3/00 G01N15/14 G01N33/50

    摘要: Particles, such as cells, are isolated for conducting single-particle measurement. Isolation of rare cells, such as circulating tumor cells (CTCs), from blood is technically challenging because they are small in numbers. An integrated microfluidic biochip, dubbed as CTC chip, was designed and fabricated for conducting tumor cell isolation. As CTCs are usually multidrug resistance (MDR), the effect of MDR inhibitors on chemotherapeutic drug accumulation in the isolated single tumor cell is measured. In this invention, label-free isolation of the rare tumor cells was conducted based on cell size difference. The major advantages of the CTC chip are the ability of fast cell isolation, followed by multiple rounds of single-cell measurement, suggesting a potential assay for detecting the drug responses based on the liquid biopsy of cancer patients.

    摘要翻译: 隔离颗粒,如细胞,进行单粒子测量。 从血液中分离罕见细胞,如循环肿瘤细胞(CTC),在技术上是具有挑战性的,因为它们的数量很少。 被设计和制造用于进行肿瘤细胞分离的集成微流体生物芯片,被称为CTC芯片。 由于CTC通常是多药耐药性(MDR),测量MDR抑制剂对分离的单个肿瘤细胞中化疗药物积累的影响。 在本发明中,基于细胞大小差异进行稀有肿瘤细胞的无标记分离。 CTC芯片的主要优点是快速细胞分离的能力,随后进行多轮单细胞测量,表明基于癌症患者的液体活检检测药物反应的潜在测定。

    Substance surface property parameter measurement method and substance surface property parameter analysis system thereof
    84.
    发明授权
    Substance surface property parameter measurement method and substance surface property parameter analysis system thereof 有权
    物质表面性质参数测量方法及物质表面性质参数分析系统

    公开(公告)号:US09157889B2

    公开(公告)日:2015-10-13

    申请号:US13125028

    申请日:2009-10-13

    IPC分类号: G01N21/00 G01N27/60 G06F11/30

    CPC分类号: G01N27/60

    摘要: A method for measuring surface property parameters of a material comprises: performing saturation processing on a surface of a material; mixing the material which has been processed by saturation with an indicating electrolyte solution; after the mixture solution achieves an balance by ion exchange, measuring the balanced concentration values of positive ions of the indicating electrolyte and H+ in the mixture solution; according to the balanced concentration values of positive ions of the indicating electrolyte, calculating surface potential of the material; and according to the surface potential of the material, calculating specific surface area and surface charge density of the material; according to surface charge density of the material, calculating surface electric field intensity; according to surface charge density and specific surface area of the material, calculating total surface charge of the material. A system for measuring surface property parameters of a material can be based on the method.

    摘要翻译: 一种用于测量材料的表面性质参数的方法包括:对材料的表面进行饱和处理; 将已经饱和处理的材料与指示性电解质溶液混合; 在混合溶液通过离子交换达到平衡后,测量混合溶液中指示电解质的正离子和H +的平衡浓度值; 根据指示电解质的正离子的平衡浓度值,计算材料的表面电位; 并根据材料的表面电位,计算材料的比表面积和表面电荷密度; 根据材料的表面电荷密度,计算表面电场强度; 根据材料的表面电荷密度和比表面积,计算材料的总表面电荷。 用于测量材料的表面性质参数的系统可以基于该方法。

    Method for link adaptation and apparatus thereof
    85.
    发明授权
    Method for link adaptation and apparatus thereof 有权
    链路自适应方法及其装置

    公开(公告)号:US08954053B2

    公开(公告)日:2015-02-10

    申请号:US13258578

    申请日:2010-06-30

    摘要: A method for link adaptation includes: classifying a radio channel; setting a set of link adaptation modes; and selecting a corresponding link adaptation mode according to a radio channel type. An apparatus for link adaptation includes: a classification module for performing a classification on a radio channel; a setting module for setting a set of link adaptation modes; and a mode selection module for selecting a corresponding link adaptation mode from the setting module according to a radio channel type of the classification. The present invention accordingly selects effective link adaptation modes in accordance with different types of radio channels, and is able to ensure to implement the maximum system throughput in different fading channels and maintain the stable and reliable link quality.

    摘要翻译: 一种用于链路自适应的方法包括:对无线电信道进行分类; 设置一组链路自适应模式; 以及根据无线电信道类型选择相应的链路适配模式。 一种用于链路自适应的装置包括:分类模块,用于在无线电信道上执行分类; 用于设置一组链路自适应模式的设置模块; 以及模式选择模块,用于根据分类的无线电信道类型从设置模块中选择相应的链路自适应模式。 因此,本发明根据不同类型的无线电信道选择有效的链路自适应模式,并且能够确保在不同衰落信道中实现最大系统吞吐量,并保持稳定可靠的链路质量。

    Ultrathin, Molecular-Sieving Graphene Oxide Membranes for Separations Along with Their Methods of Formation and Use
    86.
    发明申请
    Ultrathin, Molecular-Sieving Graphene Oxide Membranes for Separations Along with Their Methods of Formation and Use 有权
    超薄,分子筛石墨烯氧化膜与其形成和使用方法一起分离

    公开(公告)号:US20140230653A1

    公开(公告)日:2014-08-21

    申请号:US14180724

    申请日:2014-02-14

    申请人: Miao Yu Hang Li

    发明人: Miao Yu Hang Li

    IPC分类号: B01D71/06 B01D67/00

    摘要: Methods for forming an ultrathin GO membrane are provided. The method can include: dispersing a single-layered graphene oxide powder in deionized water to form a single-layered graphene oxide dispersion; centrifuging the graphene oxide dispersion to remove aggregated graphene oxide material from the single-layered graphene oxide dispersion; thereafter, diluting the single-layered graphene oxide dispersion by about ten times or more through addition of deionized water to the graphene oxide dispersion; and thereafter, passing the single-layered graphene oxide dispersion through a substrate such that a graphene oxide membrane is formed on the substrate. Filtration membranes are also provided and can include: a graphene oxide membrane having a thickness of about 1.8 nm to about 180 nm, with the graphene oxide membrane comprises about 3 to about 30 layers of graphene oxide flakes.

    摘要翻译: 提供了形成超薄GO膜的方法。 该方法可以包括:将单层石墨烯氧化物粉末分散在去离子水中以形成单层氧化石墨烯分散体; 离心氧化石墨烯分散体以从单层氧化石墨烯分散体去除聚集的石墨烯氧化物材料; 此后,通过向石墨烯氧化物分散体中加入去离子水将单层石墨烯氧化物分散体稀释约十倍或更多; 然后使单层氧化石墨烯分散体通过基板,使得在基板上形成石墨烯氧化膜。 还提供了过滤膜,并且可以包括:具有约1.8nm至约180nm厚度的石墨烯氧化物膜,石墨烯氧化物膜包含约3至约30层的氧化石墨烯薄片。

    VIBRATION WELDING SYSTEM WITH THIN FILM SENSOR
    87.
    发明申请
    VIBRATION WELDING SYSTEM WITH THIN FILM SENSOR 有权
    具有薄膜传感器的振动焊接系统

    公开(公告)号:US20130306216A1

    公开(公告)日:2013-11-21

    申请号:US13474891

    申请日:2012-05-18

    IPC分类号: B32B37/06 B23K20/10 B32B41/00

    摘要: A vibration welding system includes an anvil, a welding horn, a thin film sensor, and a process controller. The anvil and horn include working surfaces that contact a work piece during the welding process. The sensor measures a control value at the working surface. The measured control value is transmitted to the controller, which controls the system in part using the measured control value. The thin film sensor may include a plurality of thermopiles and thermocouples which collectively measure temperature and heat flux at the working surface. A method includes providing a welder device with a slot adjacent to a working surface of the welder device, inserting the thin film sensor into the slot, and using the sensor to measure a control value at the working surface. A process controller then controls the vibration welding system in part using the measured control value.

    摘要翻译: 振动焊接系统包括砧座,焊接喇叭,薄膜传感器和过程控制器。 砧座和喇叭包括在焊接过程中接触工件的工作表面。 传感器测量工作表面的控制值。 测量的控制值被发送到控制器,控制器部分地使用测量的控制值来控制系统。 薄膜传感器可以包括多个热电堆和热电偶,其共同测量工作表面处的温度和热通量。 一种方法包括:向焊接设备提供邻近焊接设备的工作表面的槽,将薄膜传感器插入槽中,并使用传感器来测量工作表面上的控制值。 然后,过程控制器部分地使用测量的控制值来控制振动焊接系统。

    AUTOMATIC SLIDE LOADING DEVICE FOR MICRO ARRAY SCANNER AND ITS METHODS OF USE
    88.
    发明申请
    AUTOMATIC SLIDE LOADING DEVICE FOR MICRO ARRAY SCANNER AND ITS METHODS OF USE 审中-公开
    用于微阵列扫描仪的自动幻灯片加载装置及其使用方法

    公开(公告)号:US20130203611A1

    公开(公告)日:2013-08-08

    申请号:US13814196

    申请日:2011-08-05

    IPC分类号: G01N21/64 B25J11/00

    摘要: An automatic slide loading device for microarray scanner comprises slide holders (1), a carrier device (2) and a positioning chamber (3), wherein the slide holder (1) can hold microarray slides (6) and the slide holder (1) is placed out of the scanning platform of the microarray scanner when the microarray scanner is in off work state, wherein the carrier device (2) is connected to the positioning chamber (3) and the carrier device (2) can load the slide holder (1) into the positioning chamber (3), wherein the positioning chamber (3) is placed above the scanning platform of the microarray scanner and is used to precisely locate the working surface of the microarray slides (6) in the slide holder (1).

    摘要翻译: 一种用于微阵列扫描器的自动滑块装载装置,包括滑动架(1),载体装置(2)和定位室(3),其中滑动架(1)可以容纳微阵列滑块(6)和滑动架(1) 当微阵列扫描仪处于关闭状态时,放置在微阵列扫描仪的扫描平台之外,其中载体装置(2)连接到定位室(3),并且载体装置(2)可以装载滑动架( 1)进入定位室(3),其中定位室(3)放置在微阵列扫描仪的扫描平台上方,并用于精确地定位载玻片保持器(1)中的微阵列滑块(6)的工作表面, 。

    Extracting Search-Focused Key N-Grams and/or Phrases for Relevance Rankings in Searches
    89.
    发明申请
    Extracting Search-Focused Key N-Grams and/or Phrases for Relevance Rankings in Searches 审中-公开
    提取搜索关键的N-gram和/或短语相关性排名搜索

    公开(公告)号:US20130173610A1

    公开(公告)日:2013-07-04

    申请号:US13339532

    申请日:2011-12-29

    申请人: Yunhua Hu Hang Li

    发明人: Yunhua Hu Hang Li

    IPC分类号: G06F17/30

    CPC分类号: G06F16/951

    摘要: An n-gram and/or phrase extraction model may be trained based at least in part on search-focused information mined from a search-query log. The n-gram and/or phrase extraction model may extract key n-grams and/or phrases from retrieved electronic documents based at least in part on features and/or characteristics of the key n-grams and/or phrases and based at least in part on features and/or characteristics of the search-focused information. The extracted key n-grams and/or phrases may be weighted. A relevancy ranking model may be trained based at least in part on the information extracted by the n-gram and/or phrase extraction model. The relevancy ranking model may provide a relevancy ranking score for electronic documents listed in a search result based at least in part on weights of extracted key n-grams and/or phrases.

    摘要翻译: 可以至少部分地基于从搜索查询日志开始的以搜索为重点的信息来训练n-gram和/或短语提取模型。 至少部分地基于关键n克和/或短语的特征和/或特征,n字和/或短语提取模型可以从检索到的电子文档中提取密钥n-gram和/或短语,并且至少基于 部分以搜索为重点的信息的特征和/或特征。 提取的键n-gram和/或短语可以被加权。 可以至少部分地基于由n-gram和/或短语提取模型提取的信息来训练相关性排名模型。 相关性排名模型可以至少部分地基于所提取的关键n-gram和/或短语的权重来提供在搜索结果中列出的电子文档的相关性排名分数。

    Cooling device for cooling electronic components
    90.
    发明授权
    Cooling device for cooling electronic components 有权
    用于冷却电子元件的冷却装置

    公开(公告)号:US08477497B2

    公开(公告)日:2013-07-02

    申请号:US12949783

    申请日:2010-11-19

    IPC分类号: H05K7/20

    摘要: A cooling device for cooling electronic components includes a base plate, a power source, and a cooling module. The cooling module includes a cooling sheet and a thermal conductive base. The cooling sheet includes a hot surface and a cooling surface. The thermal conductive base is located above the cooling surface of the cooling sheet, and configured to support electronic components on a printed circuit board and transfer heat between the electronic components and the cooling surface. When the cooling sheet is powered on, the cooling surface is in a constant state of low temperature. Due to the heat transfer between the cooling surface and the thermal conductive base, heat from the electronic components can be transferred from the thermal conductive base to the cooling surface continuously.

    摘要翻译: 用于冷却电子部件的冷却装置包括基板,电源和冷却模块。 冷却模块包括冷却片和导热基座。 冷却片包括热表面和冷却表面。 导热基座位于冷却片的冷却面的上方,构成为将印刷电路板上的电子部件支撑在电子部件与冷却面之间传递热量。 当冷却片通电时,冷却表面处于恒定的低温状态。 由于冷却表面和导热基底之间的热传递,来自电子部件的热量可以从导热基底连续传递到冷却表面。