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129 条记录 (耗时 0.03 秒)

    Modulatable power transmission clutch and a marine transmission
    82.
    发明授权
    Modulatable power transmission clutch and a marine transmission 有权
    可调式动力传动离合器和海上变速箱

    公开(公告)号：US06666312B2

    公开(公告)日：2003-12-23

    申请号：US10128755

    申请日：2002-04-24

    申请人： Gerald Matranga ,  Andrew Clark

    发明人： Gerald Matranga ,  Andrew Clark

    IPC分类号： F16D2510

    CPC分类号： B63H23/30 ,  F16D25/0638 ,  F16D25/14 ,  F16D48/02 ,  F16D48/0206 ,  F16D2048/0209 ,  F16D2048/0221 ,  F16D2048/0266 ,  F16D2500/1045 ,  F16D2500/1105 ,  F16D2500/3146 ,  F16D2500/7041

    摘要： A transmission housing having a modulatable power transmission therein which includes a clutch having interleaved clutch plates and having a central power transmitting shaft extending axially through the clutch. The clutch includes a fluid operated movable piston for effecting clutch operation by compression of the plates. The piston has a smaller piston area and a larger piston area, the smaller piston area has fluid flow directed to it at a variable fluid pressure whereby the clutch is modulatable. The larger piston area is adapted to have fluid flow directed thereto to effect maximum and unmodulatable engagement of the clutch. A spring loaded normally closed trigger valve controls fluid flow to the larger piston area in response to fluid pressure above a predetermined amount at the smaller piston area. The trigger valve is mounted on the outside of the transmission housing and is readily accessible for adjustment, for example. The trigger valve is normally closed so that pressure fluid is directed to the smaller piston area at a variable fluid pressure whereby the clutch is modulatable. When the valve is open by fluid pressure over a predetermined amount, the valve permits fluid flow to the larger piston area to effect maximum and unmodulatable engagement of the clutch for full clutch capacity.

    摘要翻译： 一种其中具有可调节动力传递的变速器壳体，其包括具有交错离合器片的离合器，并具有轴向延伸穿过离合器的中心动力传递轴。 离合器包括流体操作的可移动活塞，用于通过压板来实现离合器操作。 活塞具有较小的活塞面积和较大的活塞面积，较小的活塞面积以可变流体压力流向其中，从而离合器是可调节的。 较大的活塞面积适于使流体流动引导到其上以实现离合器的最大和不可调制的接合。 弹簧加载的常闭触发阀响应于较小活塞区域处的预定量的流体压力控制流入较大活塞面积的流体。 触发阀安装在变速器壳体的外侧，并且例如易于调节。 触发阀常闭，使得压力流体以可变的流体压力被引导到较小的活塞区域，由此离合器是可调节的。 当阀门通过流体压力超过预定量打开时，阀门允许流体流向较大的活塞区域，以实现离合器的最大和不可调制的接合以实现完全离合器的容量。

    Aerosolized active agent delivery
    83.
    发明授权
    Aerosolized active agent delivery 有权
    气雾剂活性剂输送

    公开(公告)号：US06655379B2

    公开(公告)日：2003-12-02

    申请号：US09266720

    申请日：1999-03-11

    申请人： Andrew Clark ,  George H. Foulds

    发明人： Andrew Clark ,  George H. Foulds

    IPC分类号： A61M1600

    CPC分类号： A61M15/00 ,  A61K9/0073 ,  A61M15/002

    摘要： The present invention is directed to methods and devices for delivering an active agent formulation to the lung of a human patient. The active agent formulation may be in dry powder form, it may be nebulized, or it may be in admixture with a propellant. The active agent formulation is delivered to a patient at an inspiratory flow rate of less than 17 liters per minute. The bioavailability of the active agent was found to increase at these flow rates when compared to inspiratory flow rates of 17 liters per minute or more.

    摘要翻译： 本发明涉及用于将活性剂制剂递送到人类患者的肺的方法和装置。 活性剂制剂可以是干粉形式，它可以是雾化的，或者它可以与推进剂混合。 活性剂制剂以小于17升/分钟的吸气流速输送给患者。 当与每分钟17升/分钟的吸气流速相比时，发现活性剂的生物利用度在这些流速下增加。

    Distractor straps for use with distractor apparatuses
    86.
    发明授权
    Distractor straps for use with distractor apparatuses 有权
    牵引器带用于牵引器装置

    公开(公告)号：US08845568B2

    公开(公告)日：2014-09-30

    申请号：US13435040

    申请日：2012-03-30

    申请人： Andrew Clark ,  David Chella ,  Jesse Drake

    发明人： Andrew Clark ,  David Chella ,  Jesse Drake

    IPC分类号： A61F5/04 ,  A61F5/37

    CPC分类号： A61F5/3776 ,  A61F5/04

    摘要： Distractor straps for use with distractor apparatuses are disclosed. In one embodiment, a distractor strap includes a cinch strap having a free end and a second end. The second end of the cinch strap includes an adjustment mechanism receiving the free end of the cinch strap such that the cinch strap forms a closed loop. A diameter of the closed loop is adjustable with the adjustment mechanism. The distractor strap further includes a cross strap comprising a first loop, a second loop, and strapping connecting the first loop and the second loop. The cinch strap is positioned in the first loop and the second loop such that the cross strap extends across the diameter of the closed loop formed by the cinch strap and the cross strap and the cinch strap are slidable with respect to one another.

    摘要翻译： 公开了用于牵引器装置的牵引带。 在一个实施例中，牵引带包括具有自由端和第二端的束带。 束带的第二端包括接收束带的自由端的调节机构，使得束带形成闭环。 闭环的直径可用调节机构调节。 牵引带还包括交叉带，其包括第一回路，第二回路和连接第一回路和第二回路的捆扎带。 系带位于第一环和第二环中，使得交叉带横跨由带束带形成的闭环的直径延伸，并且交叉带和带束带可相对于彼此滑动。

    Capsule package with moisture barrier
    87.
    发明授权
    Capsule package with moisture barrier 有权
    胶囊包装防潮

    公开(公告)号：US08777011B2

    公开(公告)日：2014-07-15

    申请号：US10313419

    申请日：2002-12-06

    申请人： Scot Cheu ,  William Leung ,  Mei-Chang Kuo ,  Andrew Clark

    发明人： Scot Cheu ,  William Leung ,  Mei-Chang Kuo ,  Andrew Clark

    IPC分类号： B65D83/04

    CPC分类号： B65D81/24 ,  B65D81/2015 ,  B65D81/2038

    摘要： A package for storing an aerosolizable pharmaceutical formulation comprises a capsule adapted to contain the aerosolizable pharmaceutical formulation, and a moisture barrier around the capsule. The moisture barrier comprises a material that is resistant to moisture passage, whereby the moisture barrier reduces the amount of moisture in contact with the aerosolizable pharmaceutical formulation so that the aerosolizable pharmaceutical formulation may be aerosolized when the capsule is opened. In one version, the moisture barrier comprises a metal.

    摘要翻译： 用于储存可雾化药物制剂的包装包括适于容纳可雾化药物制剂的胶囊和胶囊周围的防潮屏障。 防潮层包括耐潮湿通道的材料，由此防潮剂减少与可雾化药物制剂接触的水分量，使得当胶囊打开时可雾化的药物制剂可以雾化。 在一个版本中，防潮层包括金属。

    TREATMENT FOR PEANUT ALLERGY
    88.
    发明申请
    TREATMENT FOR PEANUT ALLERGY 有权
    PEANUT过敏症治疗

    公开(公告)号：US20140093541A1

    公开(公告)日：2014-04-03

    申请号：US14005789

    申请日：2012-03-16

    申请人： Andrew Clark ,  Pamela Ewan

    发明人： Andrew Clark ,  Pamela Ewan

    IPC分类号： C07K14/415

    CPC分类号： C07K14/415 ,  A61K39/35 ,  A61K2039/542 ,  A61K2039/545

    摘要： The present invention relates to oral immunotherapy for the desensitisation of patients who are hypersensitive to peanut allergen. The immunotherapy comprises increasing the oral dose daily dose of peanut protein administered to the patient at intervals of at least 2 weeks in a series of increments from an initial dose to a maximum dose, the series of dose increments including 2 mg, 5 mg, 12.5 mg, 25 mg, 50 mg, 100 mg, 200 mg, 400 mg and 800 mg; administering a daily oral dose of the maximum dose of peanut protein for at least 2 years and then administering a weekly oral dose of the maximum dose of peanut protein for at least 2 years.

    摘要翻译： 本发明涉及对花生过敏原过敏的患者的脱敏的口服免疫治疗。 免疫疗法包括以从初始剂量到最大剂量的一系列增量，以至少2周的间隔增加施用于患者的花生蛋白的口服剂量日剂量，所述剂量增量包括2mg，5mg，12.5 mg，25mg，50mg，100mg，200mg，400mg和800mg; 每日口服剂量的最大剂量的花生蛋白至少2年，然后每周口服剂量的最大剂量的花生蛋白质至少2年。

    IV MATERIAL PHOTONIC DEVICE ON DBR
    89.
    发明申请
    IV MATERIAL PHOTONIC DEVICE ON DBR 审中-公开
    IV物理光电器件在DBR上

    公开(公告)号：US20140077240A1

    公开(公告)日：2014-03-20

    申请号：US13621413

    申请日：2012-09-17

    申请人： Radek Roucka ,  Michael Lebby ,  Scott Semans ,  Andrew Clark

    发明人： Radek Roucka ,  Michael Lebby ,  Scott Semans ,  Andrew Clark

    IPC分类号： H01L31/0232 ,  H01L33/46

    CPC分类号： H01L31/0232 ,  H01L31/02165 ,  H01L31/02327 ,  H01L31/056 ,  H01L31/1812 ,  H01L33/10 ,  H01L33/34 ,  H01L33/46 ,  Y02E10/52

    摘要： A photonic structure including a substrate of either crystalline silicon or germanium and a multilayer distributed Bragg reflector (DBR) positioned on the substrate. The DBR includes material substantially crystal lattice matching the DBR to the substrate. The DBR includes a plurality of pairs of layers of material including any combination of IV materials and any rare earth oxide (REO). A photonic device including multilayers of single crystal IV material positioned on the DBR and including material substantially crystal lattice matching the DBR to the photonic device.

    摘要翻译： 包括晶体硅或锗的衬底和位于衬底上的多层分布式布拉格反射器（DBR）的光子结构。 DBR包括与DBR相匹配的基本晶格的材料。 DBR包括多对材料层，包括IV材料和任何稀土氧化物（REO）的任何组合。 一种光子器件，包括位于DBR上的单晶IV材料的多层，并且包括与DBR与光子器件匹配的基本上晶格的材料。

    System and method for forecasting realized volatility via wavelets and non-linear dynamics
    90.
    发明授权
    System and method for forecasting realized volatility via wavelets and non-linear dynamics 有权
    通过小波和非线性动力学预测实现波动率的系统和方法

    公开(公告)号：US08515850B2

    公开(公告)日：2013-08-20

    申请号：US13220115

    申请日：2011-08-29

    申请人： Andrew Clark ,  Jeff Kenyon

    发明人： Andrew Clark ,  Jeff Kenyon

    IPC分类号： G06Q40/00

    CPC分类号： G06Q40/04 ,  G06Q40/06

    摘要： The system and method described herein may be used to forecast realized volatility via wavelets and non-linear dynamics. In particular, a volatility time series that includes daily volatility values associated with a security may be decomposed into wavelets via multi-resolution analysis and dynamical properties associated with the individual wavelets may be analyzed to identify deterministic and non-deterministic wavelets and produce a volatility forecast derived from a fit computed on the deterministic wavelets. For example, the wavelets may be analyzed to discover time delay, Theiler, and embedding dimension values associated therewith, which may be used to project volatility values associated with each wavelet. The projected volatility values associated with each wavelet may then be summed to produce a volatility forecast associated with the security.

    摘要翻译： 本文描述的系统和方法可用于通过小波和非线性动力学预测实现的波动性。 特别地，包括与安全性相关联的每日波动值的波动性时间序列可以通过多分辨率分析被分解为小波，并且可以分析与各个小波相关联的动力特性以识别确定性和非确定性小波并产生波动性预测 从确定性小波计算的拟合得出。 例如，可以分析小波以发现与之相关的时间延迟，Theiler和嵌入维度值，其可用于投影与每个小波相关联的波动率值。 然后可以将与每个小波相关联的预测波动率相加以产生与安全性相关联的波动性预测。